S. Wert

Most-cited papers

ABCA3 gene mutations in newborns with fatal surfactant deficiency.
S. Shulenin, L. Nogee, T. Annilo, S. Wert +2 more
2004New England Journal of Medicine659 citations
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Diffuse lung disease in young children: application of a novel classification scheme.
G. Deutsch, L. Young, R. Deterding, Leland L. Fan +20 more
2007American Journal of Respiratory and Critical Care Medicine476 citations Open access
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Interleukin-1beta causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung.
U. Lappalainen, J. Whitsett, S. Wert, J. Tichelaar +1 more
2005American Journal of Respiratory Cell and Molecular Biology452 citations
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Alveolar Surfactant Homeostasis and the Pathogenesis of Pulmonary Disease
J. Whitsett, S. Wert, T. Weaver
2010Annual Review of Medicine444 citations Open access
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SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production.
Gang Chen, T. Korfhagen, Yan Xu, J. Kitzmiller +5 more
2009Journal of Clinical Investigation427 citations Open access
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Compensatory Roles of Foxa1 and Foxa2 during Lung Morphogenesis*
Hua-Jing Wan, S. Dingle, Yan Xu, V. Besnard +5 more
2005Journal of Biological Chemistry296 citations Open access
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GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis.
K. Uchida, D. Beck, Takashi Yamamoto, P. Berclaz +9 more
2007New England Journal of Medicine294 citations Open access
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SPDEF regulates goblet cell hyperplasia in the airway epithelium.
Kwon-Sik Park, T. Korfhagen, M. Bruno, J. Kitzmiller +5 more
2007Journal of Clinical Investigation293 citations Open access
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ABCA3 mutations associated with pediatric interstitial lung disease.
J. Bullard, S. Wert, J. Whitsett, M. Dean +1 more
2005American Journal of Respiratory and Critical Care Medicine290 citations Open access
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Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA
Takuji Suzuki, T. Sakagami, B. Rubin, L. Nogee +11 more
2008Journal of Experimental Medicine284 citations Open access
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Genetic Disorders of Surfactant Dysfunction
S. Wert, J. Whitsett, L. Nogee
2009Pediatric and Developmental Pathology254 citations Open access
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Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.
V. Besnard, S. Wert, W. Hull, J. Whitsett
2004Gene Expression Patterns228 citations
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Diseases of Pulmonary Surfactant Homeostasis
J. Whitsett, S. Wert, T. Weaver
2015Annual Review of Pathology227 citations Open access
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Transdifferentiation of ciliated cells during repair of the respiratory epithelium.
Kwon-Sik Park, James M. Wells, A. Zorn, S. Wert +3 more
2006American Journal of Respiratory Cell and Molecular Biology216 citations Open access
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R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
S. Bell, C. Schreiner, S. Wert, M. Mucenski +2 more
2008Development194 citations Open access
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Sox2 Is Required for Maintenance and Differentiation of Bronchiolar Clara, Ciliated, and Goblet Cells
David H. Tompkins, V. Besnard, Alexander W. Lange, S. Wert +4 more
2009PLoS ONE184 citations Open access
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A common mutation in the surfactant protein C gene associated with lung disease.
H. Cameron, M. Somaschini, P. Carrera, A. Hamvas +4 more
2005Jornal de Pediatria176 citations
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Heterogeneous pulmonary phenotypes associated with mutations in the thyroid transcription factor gene NKX2-1.
A. Hamvas, R. Deterding, S. Wert, F. White +12 more
2013Chest175 citations Open access
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Genotype-phenotype correlations for infants and children with ABCA3 deficiency.
J. Wambach, A. Casey, M. Fishman, D. Wegner +4 more
2014American Journal of Respiratory and Critical Care Medicine172 citations Open access
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Beta-catenin regulates differentiation of respiratory epithelial cells in vivo.
M. Mucenski, Jennifer M Nation, A. R. Thitoff, V. Besnard +6 more
2005American Journal of Physiology - Lung cellular and Molecular Physiology171 citations
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Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis
L. Plantier, B. Crestani, S. Wert, M. Dehoux +3 more
2011Thorax169 citations Open access
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Role of Sonic hedgehog in patterning of tracheal–bronchial cartilage and the peripheral lung
Leigh-Anne D. Miller, S. Wert, J. Clark, Yan Xu +2 more
2004Developmental Dynamics167 citations Open access
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Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy.
Takuji Suzuki, T. Sakagami, L. Young, B. Carey +11 more
2010American Journal of Respiratory and Critical Care Medicine156 citations Open access
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MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation.
S. Madala, S. Schmidt, C. Davidson, M. Ikegami +2 more
2012American Journal of Respiratory Cell and Molecular Biology155 citations Open access
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Genetic disorders influencing lung formation and function at birth.
J. Whitsett, S. Wert, B. Trapnell
2004Human Molecular Genetics154 citations
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Stat-3 is required for pulmonary homeostasis during hyperoxia.
I. Hokuto, M. Ikegami, Mitsuhiro Yoshida, K. Takeda +5 more
2004Journal of Clinical Investigation137 citations Open access
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Human GM-CSF Autoantibodies and Reproduction of Pulmonary Alveolar Proteinosis
T. Sakagami, K. Uchida, Takuji Suzuki, B. Carey +5 more
2009New England Journal of Medicine134 citations Open access
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Kruppel-like factor 5 is required for perinatal lung morphogenesis and function
Hua-Jing Wan, Feng-Ming Luo, S. Wert, Liqian Zhang +5 more
2008Development125 citations Open access
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Progressive lung disease and surfactant dysfunction with a deletion in surfactant protein C gene.
A. Hamvas, L. Nogee, F. White, P. Schuler +8 more
2004American Journal of Respiratory Cell and Molecular Biology124 citations Open access
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Sox2 activates cell proliferation and differentiation in the respiratory epithelium.
David H. Tompkins, V. Besnard, Alexander W. Lange, Angela R. Keiser +3 more
2011American Journal of Respiratory Cell and Molecular Biology123 citations Open access
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Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli.
Anne-Karina T. Perl, S. Wert, D. E. Loudy, Zhengyuan Shan +2 more
2005American Journal of Respiratory Cell and Molecular Biology113 citations Open access
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A Protocol for the Handling of Tissue Obtained by Operative Lung Biopsy: Recommendations of the chILD Pathology Co-Operative Group
C. Langston, K. Patterson, M. Dishop, Fredrick Askin +11 more
2006Pediatric and Developmental Pathology105 citations
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Expression of ABCA3 in Developing Lung and Other Tissues
M. Stahlman, V. Besnard, S. Wert, T. Weaver +5 more
2007Journal of Histochemistry and Cytochemistry100 citations Open access
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Genome-wide transcriptional profiling reveals connective tissue mast cell accumulation in bronchopulmonary dysplasia.
S. Bhattacharya, Diana Go, Daria Krenitsky, Heidie L. Huyck +7 more
2012American Journal of Respiratory and Critical Care Medicine99 citations Open access
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Patient-derived granulocyte/macrophage colony-stimulating factor autoantibodies reproduce pulmonary alveolar proteinosis in nonhuman primates.
T. Sakagami, D. Beck, K. Uchida, Takuji Suzuki +13 more
2010American Journal of Respiratory and Critical Care Medicine98 citations Open access
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Unexplained neonatal respiratory distress due to congenital surfactant deficiency.
M. Somaschini, L. Nogee, I. Sassi, O. Danhaive +6 more
2007Jornal de Pediatria82 citations
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Sox17 influences the differentiation of respiratory epithelial cells.
Kwon-Sik Park, James M. Wells, A. Zorn, S. Wert +1 more
2006Developmental Biology82 citations Open access
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Forkhead Box m1 transcription factor is required for perinatal lung function
T. Kalin, I-Ching Wang, L. Meliton, Yufang Zhang +7 more
2008Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
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Transcriptional Programs Controlling Perinatal Lung Maturation
Yan Xu, Yanhua Wang, V. Besnard, M. Ikegami +5 more
2012PLoS ONE75 citations Open access
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Sox17 is required for normal pulmonary vascular morphogenesis
Alexander W. Lange, H. Haitchi, T. LeCras, Anusha Sridharan +6 more
2014Developmental Biology74 citations Open access
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Forkhead Box M1 Transcriptional Factor is Required for Smooth Muscle Cells during Embryonic Development of Blood Vessels and Esophagus
V. Ustiyan, I-Ching Wang, X. Ren, Yufang Zhang +6 more
2009Developmental Biology73 citations Open access
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Pulmonary pathology in thyroid transcription factor-1 deficiency syndrome.
C. Galambos, H. Levy, Carolyn L. Cannon, S. Vargas +8 more
2010American Journal of Respiratory and Critical Care Medicine67 citations Open access
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Deletion of Scap in Alveolar Type II Cells Influences Lung Lipid Homeostasis and Identifies a Compensatory Role for Pulmonary Lipofibroblasts*
V. Besnard, S. Wert, M. Stahlman, A. Postle +3 more
2009Journal of Biological Chemistry67 citations Open access
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ABCA3 deficiency: neonatal respiratory failure and interstitial lung disease.
J. Bullard, S. Wert, L. Nogee
2006Seminars in Perinatology66 citations
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Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1.
V. Besnard, S. Wert, K. Kaestner, Jeffrey A. Whitsett
2005American Journal of Physiology - Lung cellular and Molecular Physiology63 citations
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Calcineurin/Nfat signaling is required for perinatal lung maturation and function.
V. Davé, Tawanna Childs, Yan Xu, M. Ikegami +6 more
2006Journal of Clinical Investigation60 citations Open access
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Comprehensive anatomic ontologies for lung development: A comparison of alveolar formation and maturation within mouse and human lung
Hua-Qin Pan, Gail H. Deutsch, S. Wert
2019Journal of Biomedical Semantics59 citations Open access
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Activation of Sterol-response Element-binding Proteins (SREBP) in Alveolar Type II Cells Enhances Lipogenesis Causing Pulmonary Lipotoxicity*
L. Plantier, V. Besnard, Yan Xu, M. Ikegami +4 more
2012Journal of Biological Chemistry57 citations Open access
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Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice.
V. Besnard, Yohei Matsuzaki, J. Clark, Yan Xu +7 more
2010American Journal of Physiology - Lung cellular and Molecular Physiology57 citations Open access
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Foxm1 Transcription Factor Is Critical for Proliferation and Differentiation of Clara Cells during Development of Conducting Airways
V. Ustiyan, S. Wert, M. Ikegami, I-Ching Wang +3 more
2012Developmental Biology55 citations Open access
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