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W. Zwart · SciRah

Researcher profile · Semantic Scholar

W. Zwart

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W. Zwart — researcher profile on SciRah

h-index: 51
Works: 240
Citations: 11K

Most-cited papers

The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer
Theresa E. Hickey, L. Selth, K. Chia, G. Laven-Law +20 more
2021Nature Medicine216 citations Open access
Semantic Scholar
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer
Alastair Davies, Shaghayegh Nouruzi, Dwaipayan Ganguli, Takeshi Namekawa +28 more
2021Nature Cell Biology140 citations Open access
Semantic Scholar
MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling
Dario Zimmerli, Chiara S. Brambillasca, Francien Talens, J. Bhin +25 more
2022Nature Communications121 citations Open access
Semantic Scholar
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair
A. Shafi, C. McNair, Jennifer J. McCann, M. Alshalalfa +16 more
2021Nature Communications116 citations Open access
Semantic Scholar
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer
S. Preković, K. Schuurman, I. Mayayo-Peralta, A. G. Manjón +26 more
2021Nature Communications75 citations Open access
Semantic Scholar
Drug-induced epigenomic plasticity reprograms circadian rhythm regulation to drive prostate cancer towards androgen-independence
S. Linder, M. Hoogstraat, S. Stelloo, Nils Eickhoff +32 more
2021medRxiv62 citations Open access
Semantic Scholar
Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer
Stanley Zhou, James R. Hawley, Fraser Soares, G. Grillo +24 more
2020Nature Communications61 citations Open access
Semantic Scholar
The 5-Hydroxymethylcytosine Landscape of Prostate Cancer
Martin Sjöström, S. Zhao, S. Levy, Meng Zhang +60 more
2022Cancer Research55 citations Open access
Semantic Scholar
Duality of glucocorticoid action in cancer: tumor-suppressor or oncogene?
I. Mayayo-Peralta, W. Zwart, S. Preković
2021Endocrine-Related Cancer53 citations Open access
Semantic Scholar
Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
Lisa N Chesner, Fanny Polesso, J. Graff, Jessica E. Hawley +36 more
2024Cancer Discovery50 citations Open access
Semantic Scholar
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer
Tiziano Bernasocchi, G. El Tekle, M. Bolis, Azzurra Mutti +28 more
2020Nature Communications41 citations Open access
Semantic Scholar
Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer
Shuang G. Zhao, M. Bootsma, Stanley Zhou, Raunak Shrestha +42 more
2024Nature Genetics40 citations Open access
Semantic Scholar
Comprehensive characterization of pre- and post-treatment samples of breast cancer reveal potential mechanisms of chemotherapy resistance
M. Hoogstraat, E. Lips, I. Mayayo-Peralta, L. Mulder +9 more
2022npj Breast Cancer37 citations Open access
Semantic Scholar
Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation
Joana Silva, F. Alkan, S. Ramalho, Goda Snieckute +11 more
2022Nature Communications32 citations Open access
Semantic Scholar
Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer
Meixia Che, Aashi Chaturvedi, S. Munro, Samuel P. Pitzen +30 more
2021Nature Communications30 citations Open access
Semantic Scholar
Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation
Sylvan C. Baca, Cassandra Singler, Soumya Zacharia, Ji-Heui Seo +19 more
2022Nature Genetics29 citations Open access
Semantic Scholar
Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation
Sylvan C. Baca, Cassandra Singler, Soumya Zacharia, Ji-Heui Seo +17 more
2021bioRxiv29 citations Open access
Semantic Scholar
The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-Cell Transcriptomics
Joseph C. Siefert, B. Cioni, M. Muraro, M. Alshalalfa +8 more
2021Molecular Cancer Research28 citations Open access
Semantic Scholar
HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia
S. Gregoricchio, Lélia Polit, Michela Esposito, J. Berthelet +12 more
2022Nucleic Acids Research27 citations Open access
Semantic Scholar
Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer
G. Grillo, Tina Keshavarzian, S. Linder, C. Arlidge +14 more
2023Cancer Discovery26 citations Open access
Semantic Scholar
Double-strand break toxicity is chromatin context independent
A. Friskes, Lisa Koob, L. Krenning, T. Severson +10 more
2022Nucleic Acids Research26 citations Open access
Semantic Scholar
Comparative transcriptomics reveals a mixed basal, club, and hillock epithelial cell identity in castration-resistant prostate cancer
Samuel P. Pitzen, A. Rudenick, Yinjie Qiu, Weijie Zhang +26 more
2025Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
Radium-223 Treatment of Patients with Metastatic Castration Resistant Prostate Cancer: Biomarkers for Stratification and Response Evaluation
K. van der Zande, W. Oyen, W. Zwart, A. Bergman
2021Cancers24 citations Open access
Semantic Scholar
Breast adipocyte size associates with ipsilateral invasive breast cancer risk after ductal carcinoma in situ
M. Almekinders, M. Schaapveld, B. Thijssen, L. Visser +12 more
2021npj Breast Cancer23 citations Open access
Semantic Scholar
Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity
S. Preković, Theofilos Chalkiadakis, Merel Roest, D. Roden +21 more
2023EMBO Molecular Medicine22 citations Open access
Semantic Scholar
Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential
J. Kneppers, T. Severson, Joseph C. Siefert, P. Schol +18 more
2022Nature Communications18 citations Open access
Semantic Scholar
TRIMming Down Hormone-Driven Cancers: The Biological Impact of TRIM Proteins on Tumor Development, Progression and Prognostication
Eleonora Pauletto, Nils Eickhoff, Nuno Padrão, C. Blattner +1 more
2021Cells18 citations Open access
Semantic Scholar
A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer
S. Palit, Jeroen van Dorp, D. Vis, C. Lieftink +5 more
2021Scientific Reports18 citations Open access
Semantic Scholar
Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells
Dorien Clarisse, S. Preković, P. Vlummens, Eleni Staessens +8 more
2023Cellular and Molecular Life Sciences17 citations Open access
Semantic Scholar
Radiogenomics Analysis Linking Multiparametric MRI and Transcriptomics in Prostate Cancer
Catarina Dinis Fernandes, A. Schaap, J. Kant, P. van Houdt +9 more
2023Cancers17 citations Open access
Semantic Scholar
Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.
Daniëlle Bianchi, Razvan Borza, E. Dezan, Guizela Huelsz-Prince +16 more
2025Science16 citations Open access
Semantic Scholar
Perturbations in 3D genome organization can promote acquired drug resistance.
A. G. Manjón, Stefano G. Manzo, S. Preković, Leon Potgeter +14 more
2023Cell Reports16 citations Open access
Semantic Scholar
Estrogen Receptor on the move: Cistromic plasticity and its implications in breast cancer.
I. Mayayo-Peralta, S. Preković, W. Zwart
2020Molecular Aspects of Medicine16 citations
Semantic Scholar
Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer
T. Severson, X. Qiu, M. Alshalalfa, Martin Sjöström +7 more
2022Clinical Epigenetics15 citations Open access
Semantic Scholar
Integrated analysis of pain, health-related quality of life, and analgesic use in patients with metastatic castration-resistant prostate cancer treated with Radium-223
S. Badrising, R. Louhanepessy, V. van der Noort, J. Kieffer +17 more
2021Prostate Cancer and Prostatic Diseases14 citations Open access
Semantic Scholar
Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases
T. Severson, Yanyun Zhu, A. D. De Marzo, T. Jones +8 more
2021Molecular Oncology14 citations Open access
Semantic Scholar
PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription
I. Mayayo-Peralta, S. Gregoricchio, K. Schuurman, Selçuk Yavuz +15 more
2022bioRxiv13 citations Open access
Semantic Scholar
Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties
M. V. van Genderen, J. Kneppers, Anniek Zaalberg, E. Bekers +3 more
2023bioRxiv12 citations Open access
Semantic Scholar
PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription
I. Mayayo-Peralta, S. Gregoricchio, K. Schuurman, Selçuk Yavuz +15 more
2023Nucleic Acids Research11 citations Open access
Semantic Scholar
Homing in on a moving target: Androgen Receptor cistromic plasticity in prostate cancer.
Nils Eickhoff, A. Bergman, W. Zwart
2022Endocrinology11 citations Open access
Semantic Scholar
Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor-driven Programs.
S. Linder, T. Severson, K. V. D. van der Mijn, E. Nevedomskaya +9 more
2023European Urology10 citations Open access
Semantic Scholar
Compartmentalization of androgen receptors at endogenous genes in living cells
Selçuk Yavuz, Hélène Kabbech, J. van Staalduinen, S. Linder +11 more
2023Nucleic Acids Research9 citations Open access
Semantic Scholar
Perturbations in 3D genome organization can promote acquired drug resistance
A. G. Manjón, D. P. Hupkes, N. Liu, A. Friskes +8 more
2021bioRxiv9 citations Open access
Semantic Scholar
Estrogen receptor 1 chromatin profiling in human breast tumors reveals high inter-patient heterogeneity with enrichment of risk SNPs and enhancer activity at most-conserved regions
S. Joosten, S. Gregoricchio, S. Stelloo, Elif Yapıcı +14 more
2024Genome Research8 citations Open access
Semantic Scholar
Emerging frontiers in androgen receptor research for prostate Cancer: insights from the 2nd international androgen receptor Symposium
J. S. Israel, Laura‑Maria Marcelin, Christian Thomas, Eva Szczyrbová +13 more
2024Journal of experimental & clinical cancer research : CR7 citations Open access
Semantic Scholar
Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer
I. Mayayo-Peralta, Beatrice Faggion, L. Hoekman, B. Morris +10 more
2021Cancers7 citations Open access
Semantic Scholar
Endometrial tumorigenesis involves epigenetic plasticity demarcating non-coding somatic mutations and 3D-genome alterations
S. Gregoricchio, Aleksandar Kojic, M. Hoogstraat, K. Schuurman +10 more
2025Genome Biology6 citations Open access
Semantic Scholar
Whole genome sequencing of 378 prostate cancer metastases reveals tissue selectivity for mismatch deficiency with potential therapeutic implications
Daniel J. Vis, S. Palit, Marie Corradi, E. Cuppen +6 more
2025Genome Medicine6 citations Open access
Semantic Scholar
Low tristetraprolin expression activates phenotypic plasticity and primes transition to lethal prostate cancer in mice
K. Morel, Beatriz German, Anis A. Hamid, Jagpreet S Nanda +19 more
2024Journal of Clinical Investigation6 citations Open access
Semantic Scholar
Inhibiting the Glucocorticoid Receptor to Enhance Chemotherapy Response.
S. Preković, W. Zwart
2023Journal of Clinical Oncology6 citations
Semantic Scholar

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