Researcher profile · Semantic Scholar

L. Krenning

h-index: 15
Works: 31
Citations: 1,562

Most-cited papers

The same, only different – DNA damage checkpoints and their reversal throughout the cell cycle
I. A. Shaltiel, L. Krenning, W. Bruinsma, R. Medema
2015Journal of Cell Science286 citations Open access
Semantic Scholar
Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent
M. Jost, Yuwen Chen, Luke A. Gilbert, M. Horlbeck +11 more
2017Molecules and Cells208 citations Open access
Semantic Scholar
Transient activation of p53 in G2 phase is sufficient to induce senescence.
L. Krenning, Femke M. Feringa, I. A. Shaltiel, J. van den Berg +1 more
2014Molecules and Cells193 citations Open access
Semantic Scholar
Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies
Nico Battich, J. Beumer, B. D. de Barbanson, L. Krenning +4 more
2020Science161 citations Open access
Semantic Scholar
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore
Julien Espeut, Dhanya K. Cheerambathur, L. Krenning, K. Oegema +1 more
2012Journal of Cell Biology157 citations Open access
Semantic Scholar
Life or Death after a Break: What Determines the Choice?
L. Krenning, J. van den Berg, R. Medema
2019Molecules and Cells90 citations Open access
Semantic Scholar
Chromosomes trapped in micronuclei are liable to segregation errors
Mar Soto, I. García-Santisteban, L. Krenning, R. Medema +1 more
2018Journal of Cell Science85 citations Open access
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Persistent repair intermediates induce senescence
F. M. Feringa, J. Raaijmakers, M. A. Hadders, C. Vaarting +4 more
2018Nature Communications70 citations Open access
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Recovery from a DNA‐damage‐induced G2 arrest requires Cdk‐dependent activation of FoxM1
Mónica Álvarez-Fernández, Vincentius A. Halim, L. Krenning, Melinda Aprelia +3 more
2010EMBO Reports64 citations Open access
Semantic Scholar
Resistance of Hypoxic Cells to Ionizing Radiation Is Mediated in Part via Hypoxia-Induced Quiescence
A. Menegakis, R. Klompmaker, C. Vennin, Aina Arbusà +6 more
2021Cells39 citations Open access
Semantic Scholar
Time-resolved single-cell sequencing identifies multiple waves of mRNA decay during the mitosis-to-G1 phase transition
L. Krenning, Stijn Sonneveld, M. Tanenbaum
2022eLife36 citations Open access
Semantic Scholar
Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent
M. Jost, Yuwen Chen, Luke A. Gilbert, M. Horlbeck +11 more
2020bioRxiv35 citations Open access
Semantic Scholar
Hypersensitivity to DNA damage in antephase as a safeguard for genome stability
Femke M. Feringa, L. Krenning, A. Koch, J. van den Berg +3 more
2016Nature Communications29 citations Open access
Semantic Scholar
Double-strand break toxicity is chromatin context independent
A. Friskes, Lisa Koob, L. Krenning, T. Severson +10 more
2022Nucleic Acids Research26 citations Open access
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A FOXO-dependent replication checkpoint restricts proliferation of damaged cells
M. Hornsveld, Femke M. Feringa, L. Krenning, J. van den Berg +6 more
2020bioRxiv20 citations Open access
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MND1 enables homologous recombination in somatic cells primarily outside the context of replication
Lisa Koob, A. Friskes, Louise van Bergen, Femke M. Feringa +8 more
2023Molecular Oncology14 citations Open access
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Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells
I. García-Santisteban, Alba Llopis, L. Krenning, Jon Vallejo-Rodríguez +3 more
2021BMC Biology14 citations Open access
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DNA end-resection in highly accessible chromatin produces a toxic break
J. van den Berg, S. Joosten, Yongsoo Kim, A. G. Manjón +8 more
2019bioRxiv12 citations Open access
Semantic Scholar
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity
Z. Pogacar, Jackie L. Johnson, L. Krenning, G. De Conti +14 more
2021bioRxiv11 citations Open access
Semantic Scholar
Time-resolved single-cell sequencing identifies multiple waves of mRNA decay during mitotic exit
L. Krenning, Stijn Sonneveld, M. Tanenbaum
2021bioRxiv6 citations Open access
Semantic Scholar
Performance of large scale pooled CRISPR screens is dependent on Cas9 expression levels
João M. Fernandes, C. Lieftink, K. Jastrzebski, L. Krenning +7 more
2021bioRxiv3 citations Open access
Semantic Scholar
Enter the nucleus to exit the cycle
L. Krenning, R. Medema
2014Cell Cycle3 citations Open access
Semantic Scholar
A novel lineage-tracing tool reveals that hypoxic tumor cells drive tumor relapse after radiotherapy
A. Menegakis, C. Vennin, J. Ient, A. J. Groot +13 more
2024Radiotherapy and Oncology2 citations Open access
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Combined Inactivation of Pocket Proteins and APC/CCdh1 by Cdk4/6 Controls Recovery from DNA Damage in G1 Phase
I. A. Shaltiel, Alba Llopis, Melinda Aprelia, R. Klompmaker +3 more
2021Cells2 citations Open access
Semantic Scholar
Early Cellular Responses to Tumor Treating Fields in Glioblastoma
Claire O'Leary, Gabriella Forte, Paul L. G. Slangen, C. V. van Heijningen +9 more
2026Neuro-Oncology Advances0 citations Open access
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OC-0511 Hypoxic tumour cells drive tumour relapse after radiotherapy as revealed by a novel tracing tool
A. Menegakis, C. Vennin, J. Ient, R. Klompmaker +8 more
2023Radiotherapy and Oncology0 citations
Semantic Scholar
CCRG-04. TARGETING THE CELL-CYCLE EFFECTS OF TUMOR TREATING FIELDS (TTFIELDS) TO INCREASE ITS EFFICACY
Paul L. G. Slangen, Basma Elbakary, Lotte W. H. G. van Mil, M. D. de Gooijer +5 more
2022Neuro-Oncology0 citations Open access
Semantic Scholar
MND1 enables repair of two-ended DNA double-strand breaks
Lisa Koob, A. Friskes, Louise van Bergen, Femke M. Feringa +7 more
2022bioRxiv0 citations Open access
Semantic Scholar
Author response: Time-resolved single-cell sequencing identifies multiple waves of mRNA decay during the mitosis-to-G1 phase transition
L. Krenning, Stijn Sonneveld, M. Tanenbaum
20210 citations Open access
Semantic Scholar
Centrosomes: Please keep your social distance!
L. Krenning, J. Raaijmakers, R. Medema
2021EMBO Journal0 citations Open access
Semantic Scholar
Cell cycle checkpoints: reversible when possible, irreversible when needed
L. Krenning
20150 citations
Semantic Scholar

×6

A. Friskes×5

Lisa Koob×4

C. Vennin×3