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T. M. Kapoor · SciRah

Researcher profile · Semantic Scholar

T. M. Kapoor

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T. M. Kapoor — researcher profile on SciRah

h-index: 62
Works: 181
Citations: 15K

Most-cited papers

Microtubule attachment and spindle assembly checkpoint signaling at the kinetochore
Emily A. Foley, T. M. Kapoor
2012Nature reviews. Molecular cell biology638 citations Open access
Semantic Scholar
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex
James Chen, B. Malone, E. Llewellyn, M. Grasso +9 more
2020bioRxiv425 citations Open access
Semantic Scholar
Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein
Ari J. Firestone, Joshua S. Weinger, M. Maldonado, Kari Barlan +5 more
2012Nature408 citations Open access
Semantic Scholar
The Kinesin-4 Protein KIF7 Regulates Mammalian Hedgehog Signaling by Organizing the Cilia Tip Compartment
Mu He, R. Subramanian, F. Bangs, T. Omelchenko +3 more
2014Nature Cell Biology290 citations Open access
Semantic Scholar
Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase
Emily A. Foley, M. Maldonado, T. M. Kapoor
2011Nature Cell Biology277 citations Open access
Semantic Scholar
Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation
M. Maldonado, T. M. Kapoor
2011Nature Cell Biology201 citations Open access
Semantic Scholar
Marking and measuring single microtubules by PRC1 and kinesin-4
R. Subramanian, S. Ti, L. Tan, S. Darst +1 more
2013Cell171 citations Open access
Semantic Scholar
Using transcriptome sequencing to identify mechanisms of drug action and resistance
Sarah A. Wacker, Benjamin R. Houghtaling, O. Elemento, T. M. Kapoor
2012Nature Chemical Biology160 citations Open access
Semantic Scholar
Centrosome repositioning in T cells is biphasic and driven by microtubule end-on capture-shrinkage
Jason Yi, Xu-Feng Wu, Andrew H. Chung, James K. Chen +2 more
2013Journal of Cell Biology155 citations Open access
Semantic Scholar
Measuring pushing and braking forces generated by ensembles of kinesin-5 crosslinking two microtubules
Y. Shimamoto, S. Forth, T. M. Kapoor
2015Developmental Cell143 citations Open access
Semantic Scholar
Human β-tubulin isotypes can regulate microtubule protofilament number and stability
S. Ti, G. Alushin, T. M. Kapoor
2018Developmental Cell138 citations Open access
Semantic Scholar
The mechanics of microtubule networks in cell division
S. Forth, T. M. Kapoor
2017Journal of Cell Biology136 citations Open access
Semantic Scholar
Direct kinetochore–spindle pole connections are not required for chromosome segregation
Vitali Sikirzhytski, V. Magidson, J. B. Steinman, Jie He +9 more
2014Journal of Cell Biology123 citations Open access
Semantic Scholar
Insights into the micromechanical properties of the metaphase spindle
Y. Shimamoto, Yusuke T. Maeda, S. Ishiwata, A. Libchaber +1 more
2011Cell118 citations Open access
Semantic Scholar
Quantitative Chemical Proteomics Approach to Identify Posttranslational Modification-mediated Protein-protein Interactions
X. Li, Emily A. Foley, K. Molloy, Yinyin Li +2 more
2012Journal of the American Chemical Society116 citations Open access
Semantic Scholar
DrugTargetSeqR: a genomics- and CRISPR/Cas9-based method to analyze drug targets
Corynn Kasap, O. Elemento, T. M. Kapoor
2014Nature Chemical Biology112 citations Open access
Semantic Scholar
Asymmetric molecular architecture of the human γ-tubulin ring complex
M. Wieczorek, L. Urnavicius, S. Ti, K. Molloy +2 more
2019bioRxiv109 citations Open access
Semantic Scholar
Diacylglycerol promotes centrosome polarization in T cells via reciprocal localization of dynein and myosin II
Xin Liu, T. M. Kapoor, James K. Chen, M. Huse
2013Proceedings of the National Academy of Sciences of the United States of America106 citations Open access
Semantic Scholar
Mutations in human tubulin proximal to the kinesin binding site alter dynamic instability at microtubule plus- and minus-ends
S. Ti, M. C. Pamula, S. Howes, Christian Duellberg +6 more
2016Developmental Cell102 citations Open access
Semantic Scholar
Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response
R. Kleiner, P. Verma, K. Molloy, B. Chait +1 more
2015Nature Chemical Biology100 citations Open access
Semantic Scholar
The structured core of human β tubulin confers isotype-specific polymerization properties
M. C. Pamula, S. Ti, T. M. Kapoor
2016Journal of Cell Biology91 citations Open access
Semantic Scholar
Building Complexity: Insights into Self-organized Assembly of Microtubule-based Architectures
R. Subramanian, T. M. Kapoor
2012Developmental Cell87 citations Open access
Semantic Scholar
Asymmetric friction of non-motor MAPs can lead to their directional motion in active microtubule networks
S. Forth, K. Hsia, Y. Shimamoto, T. M. Kapoor
2014Cell83 citations Open access
Semantic Scholar
Reconstitution of the augmin complex provides insights into its architecture and function
K. Hsia, E. Wilson-Kubalek, A. Dottore, Q. Hao +5 more
2014Nature Cell Biology82 citations Open access
Semantic Scholar
Near-atomic cryo-EM structure of PRC1 bound to the microtubule
E. Kellogg, S. Howes, S. Ti, E. Ramírez-Aportela +3 more
2016Proceedings of the National Academy of Sciences of the United States of America73 citations Open access
Semantic Scholar
Chemical strategies to overcome resistance against targeted anticancer therapeutics
R. Pisa, T. M. Kapoor
2020Nature Chemical Biology72 citations Open access
Semantic Scholar
Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis
S. A. Kawashima, Zhen Chen, Yuki Aoi, Anupam Patgiri +3 more
2016Cell69 citations Open access
Semantic Scholar
A chemical proteomics approach to reveal direct protein-protein interactions in living cells
R. Kleiner, Lisa E. Hang, K. Molloy, B. Chait +1 more
2017Cell Chemical Biology67 citations Open access
Semantic Scholar
Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase
Keith J. Mickolajczyk, Patrick M. M. Shelton, M. Grasso, Xiaocong Cao +4 more
2020bioRxiv59 citations Open access
Semantic Scholar
Metaphase Spindle Assembly
T. M. Kapoor
2017Biology52 citations Open access
Semantic Scholar
High-resolution imaging reveals how the spindle midzone impacts chromosome movement
M. C. Pamula, Lina Carlini, S. Forth, P. Verma +5 more
2019Journal of Cell Biology51 citations Open access
Semantic Scholar
Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division
L. Tan, T. M. Kapoor
2011Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
MZT Proteins Form Multi-Faceted Structural Modules in the γ-Tubulin Ring Complex
M. Wieczorek, Tzu-Lun Huang, L. Urnavicius, K. Hsia +1 more
2020Cell Reports48 citations Open access
Semantic Scholar
Structural Insights into Mdn1, an Essential AAA Protein Required for Ribosome Biogenesis
Zhen Chen, Hiroshi Suzuki, Y. Kobayashi, A. Wang +4 more
2018Cell48 citations Open access
Semantic Scholar
Analyzing Fission Yeast Multidrug Resistance Mechanisms to Develop a Genetically Tractable Model System for Chemical Biology
S. A. Kawashima, Ai Takemoto, P. Nurse, T. M. Kapoor
2012Chemistry and Biology44 citations Open access
Semantic Scholar
Non-centrosomal microtubules at kinetochores promote rapid chromosome biorientation during mitosis in human cells
Fioranna Renda, Christopher E. Miles, I. Tikhonenko, Rebecca L. Fisher +4 more
2022Current Biology37 citations Open access
Semantic Scholar
Designing a chemical inhibitor of the AAA protein spastin using active site mutations
T. Cupido, R. Pisa, M. E. Kelley, T. M. Kapoor
2019Nature Chemical Biology37 citations Open access
Semantic Scholar
Examining post‐translational modification‐mediated protein–protein interactions using a chemical proteomics approach
Xia Li, Emily A. Foley, S. A. Kawashima, K. Molloy +3 more
2013Protein Science36 citations Open access
Semantic Scholar
Leveraging Chemotype-specific Resistance for Drug Target Identification and Chemical Biology
T. M. Kapoor, Randy M. Miller
2017TIPS - Trends in Pharmacological Sciences34 citations Open access
Semantic Scholar
Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function
M. Wieczorek, S. Ti, L. Urnavicius, K. Molloy +3 more
2020bioRxiv31 citations Open access
Semantic Scholar
Microtubules enhance mesoscale effective diffusivity in the crowded metaphase cytoplasm
Lina Carlini, G. Brittingham, L. Holt, T. M. Kapoor
2020Developmental Cell28 citations Open access
Semantic Scholar
Microneedle-based analysis of the micromechanics of the metaphase spindle assembled in Xenopus laevis egg extracts
Y. Shimamoto, T. M. Kapoor
2012Nature Protocols28 citations Open access
Semantic Scholar
Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity
Stephanie K. See, S. Hoogendoorn, Andrew H. Chung, Fan Ye +9 more
2015ACS Chemical Biology26 citations Open access
Semantic Scholar
Dissecting the first and the second meiotic divisions using a marker-less drug-hypersensitive fission yeast
Yuki Aoi, Masamitsu Sato, T. Sutani, K. Shirahige +2 more
2014Cell Cycle24 citations Open access
Semantic Scholar
Micromechanics of the vertebrate meiotic spindle examined by stretching along the pole-to-pole axis.
Jun Takagi, T. Itabashi, Kazuya Suzuki, Y. Shimamoto +2 more
2014Biophysical Journal23 citations Open access
Semantic Scholar
Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action
J. B. Steinman, C. Santarossa, Randy M. Miller, Lola Yu +18 more
2017eLife22 citations Open access
Semantic Scholar
Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
Sinduja K. Marx, Keith J. Mickolajczyk, Jonathan M. Craig, Christopher M Thomas +10 more
2023Nucleic Acids Research20 citations Open access
Semantic Scholar
Purification of Affinity Tag-free Recombinant Tubulin from Insect Cells
S. Ti, M. Wieczorek, T. M. Kapoor
2020STAR Protocols19 citations Open access
Semantic Scholar
A chemical biology strategy to analyze rheostat-like protein kinase-dependent regulation
S. A. Kawashima, Ai Takemoto, P. Nurse, T. M. Kapoor
2013Chemistry and Biology18 citations Open access
Semantic Scholar
Using ‘biased-privileged’ scaffolds to identify lysine methyltransferase inhibitors
Sudhir Kashyap, Joel S. Sandler, U. Peters, E. Martinez +1 more
2014Bioorganic & Medicinal Chemistry15 citations Open access
Semantic Scholar

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Y. Shimamoto×6
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S. A. Kawashima×6

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Emily A. Foley×4

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