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Corynn Kasap · SciRah

Researcher profile · Semantic Scholar

Corynn Kasap

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Corynn Kasap — researcher profile on SciRah

h-index: 11
Works: 37
Citations: 1,511

Most-cited papers

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
K. Roberts, Ryan D. Morin, Jing-Hui Zhang, M. Hirst +45 more
2012Cancer Cell720 citations Open access
Semantic Scholar
Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis.
N. Shah, Corynn Kasap, Christopher A. Weier, M. Balbas +4 more
2008Cancer Cell236 citations Open access
Semantic Scholar
Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations
M. Seeliger, Pratistha Ranjitkar, Corynn Kasap, Y. Shan +4 more
2009Cancer Research141 citations Open access
Semantic Scholar
DrugTargetSeqR: a genomics- and CRISPR/Cas9-based method to analyze drug targets
Corynn Kasap, O. Elemento, T. M. Kapoor
2014Nature Chemical Biology112 citations Open access
Semantic Scholar
The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance
Ian D. Ferguson, B. Patiño-Escobar, S. Tuomivaara, Y. Lin +25 more
2022Nature Communications92 citations Open access
Semantic Scholar
Preliminary Clinical Activity in a Phase I Trial of the BCR-ABL/IGF- 1R/Aurora Kinase Inhibitor XL228 in Patients with Ph++ Leukemias with Either Failure to Multiple TKI Therapies or with T315I Mutation
J. Cortes, R. Paquette, M. Talpaz, J. Pinilla +7 more
200850 citations
Semantic Scholar
Structural surfaceomics reveals an AML-specific conformation of integrin β2 as a CAR T cellular therapy target
Kamal Mandal, G. Wicaksono, Clinton Yu, Jarrett J. Adams +32 more
2023Nature Cancer40 citations Open access
Semantic Scholar
Targeting Drug-Resistant CML and Ph+-ALL with the Spectrum Selective Protein Kinase Inhibitor XL228.
N. Shah, Corynn Kasap, R. Paquette, J. Cortes +4 more
200724 citations
Semantic Scholar
Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma
Ian D. Ferguson, Y. Lin, C. Lam, H. Shao +16 more
2022Cell Chemical Biology15 citations Open access
Semantic Scholar
Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer
Kevin Chang, Henry Delavan, Elizabeth Yip, Corynn Kasap +22 more
2025Nature Communications13 citations
Semantic Scholar
Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells
Corynn Kasap, Adila Izgutdina, B. Patiño-Escobar, Amrik S. Kang +31 more
2024bioRxiv13 citations Open access
Semantic Scholar
Bladder cancer variants share aggressive features including a CA125+ cell state and targetable TM4SF1 expression
Heiko Yang, Hanbing Song, Elizabeth Yip, Tim Gilpatrick +15 more
2025Nature Communications12 citations Open access
Semantic Scholar
Assessing Large Language Models for Oncology Data Inference From Radiology Reports
Li-Ching Chen, T. Zack, Arda Demirci, Madhumita Sushil +5 more
2024medRxiv12 citations Open access
Semantic Scholar
Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
Corynn Kasap, Adila Izgutdina, B. Patiño-Escobar, Amrik S. Kang +41 more
2025Blood10 citations Open access
Semantic Scholar
Novel Chromosomal Rearrangements and Sequence Mutations in High-Risk Ph-Like Acute Lymphoblastic Leukemia
K. Roberts, Ryan D. Morin, Jing-Hui Zhang, M. Hirst +17 more
20119 citations
Semantic Scholar
Discovery and Development of CD70 As a Cellular Therapy Target in High Risk Multiple Myeloma
Corynn Kasap, Adila Izgutdina, Bonell Patiño Escobar, Y. Lin +16 more
2023Blood4 citations
Semantic Scholar
Structural Surfaceomics Reveals an AML-Specific Conformation of Integrin-β2 As an Immunotherapeutic Target
Kamal Mandal, G. Wicaksono, Clinton Yu, Jarrett J. Adams +24 more
2022Blood4 citations Open access
Semantic Scholar
Single Molecule Real Time (SMRT™) Sequencing Sensitively Detects Polyclonal and Compound BCR-ABL in Patients Who Relapse on Kinase Inhibitor Therapy,
Catherine C. Smith, Michael Brown, J. Chin, Corynn Kasap +7 more
20113 citations
Semantic Scholar
Bicistronic CAR T-cells Against CD70 & Active Integrin β2 Overcome Antigen Heterogeneity and Preserve Safety in Acute Myeloid Leukemia
Amrik S. Kang, Haley Johnson, Nicole Lei, J. Wong +13 more
2025bioRxiv2 citations Open access
Semantic Scholar
Abstract B074: Clinical inference of location and trajectory of pancreatic cancer from radiology reports using zero-shot LLM
T. Zack, Madhumita Sushil, Brenda Miao, Arda Demirci +4 more
2024Cancer Research2 citations
Semantic Scholar
P-103: Profiling the myeloma cell surface proteome reveals CCR10 as a potential immunotherapeutic target
B. Patiño-Escobar, Corynn Kasap, Ian D. Ferguson, Martina Hale +1 more
2021Clinical Lymphoma, Myeloma & Leukemia2 citations
Semantic Scholar
Functional multiomics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma
P. Choudhry, Corynn Kasap, B. Patiño-Escobar, O. Gugliemini +18 more
2021bioRxiv2 citations Open access
Semantic Scholar
Structural surfaceomics reveals an AML-specific conformation of Integrin-β2 as a CAR-T therapy target
Kamal Mandal, G. Wicaksono, Clinton Yu, Jarrett J. Adams +24 more
2022bioRxiv1 citations Open access
Semantic Scholar
Beyond the Gatekeeper: Imatinib- and Dasatinib-Resistant BCR-ABL/F317 Mutations Confer Cross-Resistance to VX-680 but Are Sensitive to a Structural Derivative of VX-680
Corynn Kasap, Nicholas T. Hertz, D. Makino, K. Shokat +2 more
20081 citations
Semantic Scholar
Abstract 2667: TM4SF1 as a novel tumor-associated antigen in biliary tract cancers targetable by immune effector cell therapy
Lorraine Nuniz, Julia H. Pham, Juliette Jacques, Josephine A. Hinneh +10 more
2026Cancer Research0 citations
Semantic Scholar
PA-324 Optimized Computationally Engineered CD70-Targeting Virus-Free CRISPR Knock-in CAR T Cells for High-Risk Multiple Myeloma
B. Patiño-Escobar, Daniel D. Waller, Corynn Kasap, Amrik S. Kang +11 more
2026Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
Effective imaging and treatment of Acute Myeloid Leukemia with radiotheranostics targeting the activated conformation of integrin-βeta2
Anju Wadhwa, Haley Johnson, K. Bobba, A. Bidkar +25 more
2025bioRxiv0 citations Open access
Semantic Scholar
Effective imaging and treatment of Acute Myeloid Leukemia with radiotheranostics targeting the activated conformation of integrin-βeta2
Anju Wadhwa, Haley Johnson, K. Bobba, A. Bidkar +25 more
2025Research Square0 citations
Semantic Scholar
Abstract 6405: Identification of molecular targets in bladder cancer variants using single-cell analysis
Heiko Yang, Hanbing Song, Paul Allegakoen, Kevin L. Lu +12 more
2024Cancer Research0 citations
Semantic Scholar
MP65-20 BLADDER CANCER PATIENT-DERIVED ORGANOIDS: A NEW FRONTIER FOR PERSONALIZED THERAPY
Heiko Yang, Hanbing Song, Paul Allegakoen, Kevin L. Lu +12 more
2024Journal of Urology0 citations
Semantic Scholar
Histologic variants in bladder cancer harbor aggressive molecular features including TM4SF1 expression and a CA125+ cell state
Heiko Yang, Hanbing Song, Elizabeth Yip, Kevin Chang +14 more
2024bioRxiv0 citations Open access
Semantic Scholar
HLA-Pan-DP CAR-T Demonstrates Cytotoxicity Against Multiple Hematological Malignancies
Hiroyuki Takamatsu, Emilio Ramos, B. Patiño-Escobar, Corynn Kasap +12 more
2024Blood0 citations
Semantic Scholar
Abstract PR008: Modulating the PPARγ pathway to augment NECTIN4-targeting chimeric antigen receptor (CAR) T cell therapy
Kevin Chang, Henry Delavan, Jun Zhu, Corynn Kasap +11 more
2024Clinical Cancer Research0 citations
Semantic Scholar
Abstract NG02: Polyclonal and heterogeneous resistance to targeted therapy in leukemia
Catherine C. Smith, A. Paguirigan, C. Chin, Michael P. Brown +8 more
20150 citations
Semantic Scholar
Abstract 1659: The mechanism of action of clinically effective dual Abl/Aurora kinase inhibitors does not involve BCR-ABL inhibition
J. Gajan, Corynn Kasap, N. Shah
20100 citations
Semantic Scholar
Src Thr338Ile inhibited in the DFG-Asp-Out conformation
M. Seeliger, Pratistha Ranjitkar, Corynn Kasap, Y. Shan +4 more
20090 citations
Semantic Scholar
Optimal Treatment for Patients after Dasatinib or Nilotinib: Comparison of Preclinical Activities of Approved and Promising Investigational Kinase Inhibitors Against BCR-ABL Kinase Domain Mutations That Confer Clinical Resistance to Dasatinib or Nilotinib.
Corynn Kasap, Christopher A. Weier, N. Shah
20070 citations
Semantic Scholar

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