Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Sukumaran · SciRah

Researcher profile · Semantic Scholar

S. Sukumaran

Share profile

S. Sukumaran — researcher profile on SciRah

h-index: 25
Works: 58
Citations: 1,972

Most-cited papers

Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing
Ji Li, N. Stagg, Jennifer Johnston, Michael J. Harris +20 more
2017Cancer Cell289 citations Open access
Semantic Scholar
Circadian rhythms: influence on physiology, pharmacology, and therapeutic interventions
Vivaswath S. Ayyar, S. Sukumaran
2021Journal of Pharmacokinetics and Pharmacodynamics159 citations Open access
Semantic Scholar
Circadian Rhythms in Gene Expression: Relationship to Physiology, Disease, Drug Disposition and Drug Action
S. Sukumaran, R. Almon, D. Dubois, W. Jusko
2010Advanced Drug Delivery Reviews145 citations Open access
Semantic Scholar
An anti-CD3/anti-CLL-1 bispecific antibody for the treatment of acute myeloid leukemia.
S. Leong, S. Sukumaran, Maria Hristopoulos, K. Totpal +19 more
2017Blood142 citations Open access
Semantic Scholar
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
Tianhe Sun, Zhiyu Huang, Wei-Ching Liang, Jianping Yin +31 more
2021Science Translational Medicine119 citations Open access
Semantic Scholar
An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma
H. Maun, J. Jackman, D. Choy, K. Loyet +46 more
2019Cell95 citations Open access
Semantic Scholar
Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action.
S. Sukumaran, W. Jusko, D. Dubois, R. Almon
2011Journal of applied physiology78 citations Open access
Semantic Scholar
An in vitro FcRn- dependent transcytosis assay as a screening tool for predictive assessment of nonspecific clearance of antibody therapeutics in humans
Shan Chung, V. Nguyen, Y. Lin, J. Lafrance-Vanasse +14 more
2019mAbs63 citations Open access
Semantic Scholar
Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology.
S. Sukumaran, B. Xue, W. Jusko, D. Dubois +1 more
2010Physiological Genomics62 citations Open access
Semantic Scholar
Adipose Tissue Deficiency and Chronic Inflammation in Diabetic Goto-Kakizaki Rats
B. Xue, S. Sukumaran, Jing Nie, W. Jusko +2 more
2011PLoS ONE60 citations Open access
Semantic Scholar
Pre‐clinical and translational pharmacology of a human interleukin‐22 IgG fusion protein for potential treatment of infectious or inflammatory diseases
E. Stefanich, J. Rae, S. Sukumaran, Jeff Lutman +8 more
2018Biochemical Pharmacology54 citations
Semantic Scholar
Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for THIOMAB™ Drug Conjugates
S. Sukumaran, K. Gadkar, Crystal Zhang, Sunil Bhakta +10 more
2014Pharmaceutical Research45 citations
Semantic Scholar
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members
Yanli Yang, Sherry H. Yeh, Shravan Madireddi, W. Matochko +18 more
2019mAbs44 citations Open access
Semantic Scholar
Glucocorticoid Effects on Adiponectin Expression
S. Sukumaran, D. Dubois, W. Jusko, R. Almon
2012Vitamins and hormones44 citations Open access
Semantic Scholar
A PK/PD Analysis of Circulating Biomarkers and Their Relationship to Tumor Response in Atezolizumab‐Treated non‐small Cell Lung Cancer Patients
Ida Netterberg, Chi-Chung Li, L. Molinero, N. Budha +4 more
2018Clinical pharmacology and therapy40 citations Open access
Semantic Scholar
Differential Muscle Gene Expression as a Function of Disease Progression in Goto-Kakizaki Diabetic Rats
Jing Nie, B. Xue, S. Sukumaran, W. Jusko +2 more
2011Molecular and Cellular Endocrinology39 citations Open access
Semantic Scholar
Evidence for a Glucocorticoid Receptor Beta Splice Variant in the Rat and Its Physiological Regulation in Liver
D. Dubois, S. Sukumaran, W. Jusko, R. Almon
2012Steroids37 citations Open access
Semantic Scholar
gPKPDSim: a SimBiology®-based GUI application for PKPD modeling in drug development
I. Hosseini, A. Gajjala, Daniela Bumbaca-Yadav, S. Sukumaran +3 more
2018Journal of Pharmacokinetics and Pharmacodynamics34 citations Open access
Semantic Scholar
Highly Multiplexed and Reproducible Ion-Current-Based Strategy for Large-Scale Quantitative Proteomics and the Application to Protein Expression Dynamics Induced by Methylprednisolone in 60 Rats
benjamin Nouri Nigjeh, S. Sukumaran, Cheng-Jian Tu, Jun Li +6 more
2014Analytical Chemistry34 citations Open access
Semantic Scholar
Exposing the molecular heterogeneity of glycosylated biotherapeutics
Luis F. Schachner, Christopher H. Mullen, Wilson Phung, Joshua D. Hinkle +16 more
2023bioRxiv33 citations Open access
Semantic Scholar
Preclinical and translational pharmacokinetics of a novel THIOMAB™ antibody-antibiotic conjugate against Staphylococcus aureus
R. Deng, Chenguang Zhou, Dong-Wei Li, Hao Cai +7 more
2019mAbs33 citations Open access
Semantic Scholar
Mechanistic Modeling of the Effects of Glucocorticoids and Circadian Rhythms on Adipokine Expression
S. Sukumaran, W. Jusko, D. Dubois, R. Almon
2011Journal of Pharmacology and Experimental Therapeutics33 citations Open access
Semantic Scholar
Characterization of JNJ-80948543, a Novel CD79bxCD20xCD3 Trispecific T-Cell Redirecting Antibody for the Treatment of B-Cell Non-Hodgkin Lymphoma
Anna Kuchnio, Danlin Yang, N. Vloemans, Cassandra L. Lowenstein +20 more
2022Blood30 citations Open access
Semantic Scholar
Functional Proteomic Analysis of Corticosteroid Pharmacodynamics in Rat Liver: Relationship to Hepatic Stress, Signaling, Energy Regulation, and Drug Metabolism
Vivaswath S. Ayyar, R. Almon, D. Dubois, S. Sukumaran +2 more
2017Journal of Proteomics26 citations Open access
Semantic Scholar
Variability in Zucker diabetic fatty rats: differences in disease progression in hyperglycemic and normoglycemic animals
Xi Wang, D. Dubois, S. Sukumaran, Vivaswath S. Ayyar +2 more
2014Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy26 citations Open access
Semantic Scholar
Circadian signatures in rat liver: from gene expression to pathways
Meric A. Ovacik, S. Sukumaran, R. Almon, D. Dubois +2 more
2010BMC Bioinformatics24 citations Open access
Semantic Scholar
Development and Translational Application of an Integrated, Mechanistic Model of Antibody-Drug Conjugate Pharmacokinetics
S. Sukumaran, Crystal Zhang, D. Leipold, Ola M. Saad +10 more
2016AAPS Journal22 citations
Semantic Scholar
Tandem Analysis of Transcriptome and Proteome Changes after a Single Dose of Corticosteroid: A Systems Approach to Liver Function in Pharmacogenomics
Kubra Kamisoglu, S. Sukumaran, benjamin Nouri Nigjeh, Cheng-Jian Tu +8 more
2015Omics21 citations Open access
Semantic Scholar
Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone Effects on iNOS mRNA Expression and Nitric Oxide During LPS-Induced Inflammation in Rats
S. Sukumaran, E. Lepist, D. Dubois, R. Almon +1 more
2012Pharmaceutical Research15 citations Open access
Semantic Scholar
Dose‐dependent inactivation of airway tryptase with a novel dissociating anti‐tryptase antibody (MTPS9579A) in healthy participants: A randomized trial
Sharon M. Rymut, S. Sukumaran, Gizette Sperinde, Meire C. D. Bremer +12 more
2021Clinical and Translational Science14 citations Open access
Semantic Scholar
Nonclinical safety assessment of a human interleukin‐22FC IG fusion protein demonstrates in vitro to in vivo and cross‐species translatability
Donna W. Lee, Shelly Zhong, R. Pai, J. Rae +10 more
2018Pharmacology Research & Perspectives14 citations Open access
Semantic Scholar
Effects of High Fat Feeding on Liver Gene Expression in Diabetic Goto-Kakizaki Rats
R. Almon, D. Dubois, S. Sukumaran, Xi Wang +3 more
2012Gene Regulation and Systems Biology14 citations Open access
Semantic Scholar
Meta-Modeling of Methylprednisolone Effects on Glucose Regulation in Rats
Jing Fang, S. Sukumaran, D. Dubois, R. Almon +1 more
2013PLoS ONE12 citations Open access
Semantic Scholar
Nonclinical Pharmacokinetics and Pharmacodynamics Characterization of Anti-CD79b/CD3 T Cell-Dependent Bispecific Antibody Using a Surrogate Molecule: A Potential Therapeutic Agent for B Cell Malignancies
Rajbharan Yadav, S. Sukumaran, T. Zabka, Jin-Ze Li +15 more
2022Pharmaceutics9 citations Open access
Semantic Scholar
Modeling Corticosteroid Pharmacogenomics and Proteomics in Rat Liver
Vivaswath S. Ayyar, S. Sukumaran, D. Dubois, R. Almon +1 more
2018Journal of Pharmacology and Experimental Therapeutics9 citations Open access
Semantic Scholar
Integrated systems modeling of severe asthma: Exploration of IL‐33/ST2 antagonism
K. Gadkar, Justin Feigelman, S. Sukumaran, M. Rodrigo +7 more
2022CPT: Pharmacometrics & Systems Pharmacology8 citations Open access
Semantic Scholar
An anti-CD 3 / anti – CLL-1 bispeci fi c antibody for the treatment of acute myeloid leukemia
S. Leong, S. Sukumaran, Maria Hristopoulos, K. Totpal +19 more
20168 citations
Semantic Scholar
An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.
H. Maun, J. Jackman, D. Choy, K. Loyet +46 more
2020Cell7 citations Open access
Semantic Scholar
Receptor/gene/protein-mediated signaling connects methylprednisolone exposure to metabolic and immune-related pharmacodynamic actions in liver
Vivaswath S. Ayyar, S. Sukumaran, D. Dubois, R. Almon +2 more
2018Journal of Pharmacokinetics and Pharmacodynamics7 citations Open access
Semantic Scholar
Anti-FcRH5/CD3 T Cell Dependent Bispecific Antibody (TDB) for the Treatment of Multiple Myeloma
Ji Li, N. Stagg, Jennifer Johnston, Michael J. Harris +18 more
20165 citations
Semantic Scholar
Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases.
Rajbharan Yadav, S. Sukumaran, Jeff Lutman, Mayur S. Mitra +17 more
2023Journal of Pharmacy and Science4 citations Open access
Semantic Scholar
Challenges with development of a pharmacokinetics assay to measure a variably glycosylated fusion protein.
Gizette Sperinde, Luna Liu, Keyang Xu, T. Bentley +6 more
2021Bioanalysis4 citations
Semantic Scholar
424 Nonclinical safety assessment of a humanized anti-OX40 agonist antibody, MOXR0916
R. Prell, W. Halpern, J. Beyer, J. Tarrant +12 more
20144 citations
Semantic Scholar
1598PTRANSLATIONAL PKPD OF DNIB0600A, AN ANTI-NAPI2B-VC-MMAE ADC IN OVARIAN AND NSCLC CANCERS.
Ke-Dan Lin, S. Sukumaran, J. Xu, Crystal Zhang +4 more
2014Annals of Oncology4 citations Open access
Semantic Scholar
A mechanistic PK/PD model to enable dose selection of the potent anti‐tryptase antibody (MTPS9579A) in patients with moderate‐to‐severe asthma
Sharon M. Rymut, Lindsay M. Henderson, Victor Poon, T. Staton +6 more
2023Clinical and Translational Science2 citations Open access
Semantic Scholar
Local Airway Concentration of Anti-Tryptase Antibody (MTPS9579A) Predicts Extent of Tryptase Disruption
Sharon M. Rymut, Kenta Yoshida, S. Sukumaran, Fang Cai +5 more
20201 citations Open access
Semantic Scholar
1846P Phase Ib, international, dose-escalation study to evaluate the safety, pharmacokinetics (PK) and efficacy of ST-617 a dithiolethione, for the attenuation of oral mucositis (OM) in patients receiving chemoradiation (CRT) for head & neck (H&N) cancer
D. Osei-Fofie, G. Landers, J. Wetter, P. Kraus +11 more
20201 citations Open access
Semantic Scholar
Late Breaking Abstract - Dose-dependent inactivation of airway tryptase with a novel dissociating anti-Tryptase antibody (MTPS9579A) in healthy volunteers
T. Staton, S. Sukumaran, Sharon M. Rymut, Gizette Sperinde +8 more
2019Airway pharmacology and treatment1 citations
Semantic Scholar
Pharmacokinetics/Pharmacodynamics and Disposition of Antibody-Drug Conjugates
S. Sukumaran, Ke-Dan Lin
20151 citations
Semantic Scholar
209 Pre-clinical and translational pharmacology, pharmacokinetics and pharmacodynamics for a humanized anti-OX40 antibody MOXR0916, a T-cell agonist in the treatment of solid tumors
S. Sukumaran, Jeong Kim, M. Huseni, J. Ruppel +6 more
20141 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Almon×18
Invite
R. Almon — researcher profile on SciRah
D. Dubois×18
Invite
D. Dubois — researcher profile on SciRah
W. Jusko×17
Invite
W. Jusko — researcher profile on SciRah
Crystal Zhang×7
Invite
Crystal Zhang — researcher profile on SciRah

×7

Invite

Ke-Dan Lin — researcher profile on SciRah

Invite

Jeff Lutman — researcher profile on SciRah

Invite

T. Staton — researcher profile on SciRah

S. Ramanujan×6

Invite

S. Ramanujan — researcher profile on SciRah

Invite

K. Totpal — researcher profile on SciRah

Diego A. Ellerman×5

Invite

Diego A. Ellerman — researcher profile on SciRah

Vivaswath S. Ayyar×5

Invite

Vivaswath S. Ayyar — researcher profile on SciRah

Gizette Sperinde×5

Invite

Gizette Sperinde — researcher profile on SciRah