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Ruth Wang · SciRah

Researcher profile · Semantic Scholar

Ruth Wang

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Ruth Wang — researcher profile on SciRah

h-index: 12
Works: 18
Citations: 1,187

Most-cited papers

Crystal structures of HIV-1 reverse transcriptase with etravirine (TMC125) and rilpivirine (TMC278): implications for drug design.
E. Lansdon, K. Brendza, Magdeleine Hung, Ruth Wang +5 more
2010Journal of Medicinal Chemistry226 citations
Semantic Scholar
Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer
D. Marshall, S. Lyman, S. McCauley, Maria I. Kovalenko +13 more
2015PLoS ONE195 citations Open access
Semantic Scholar
Cathepsin A Is the Major Hydrolase Catalyzing the Intracellular Hydrolysis of the Antiretroviral Nucleotide Phosphonoamidate Prodrugs GS-7340 and GS-9131
G. Birkuš, Ruth Wang, Xiao-Hong Liu, N. Kutty +6 more
2006Antimicrobial Agents and Chemotherapy171 citations Open access
Semantic Scholar
Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ
J. Somoza, David Koditek, A. Villaseñor, Nikolai Novikov +10 more
2015Journal of Biological Chemistry127 citations Open access
Semantic Scholar
Visualizing ATP-dependent RNA Translocation by the NS3 Helicase from HCV
T. Appleby, R. Anderson, O. Fedorova, A. Pyle +4 more
2010Journal of Molecular Biology118 citations Open access
Semantic Scholar
A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT
K. White, N. Margot, John K. Ly, James M. Chen +6 more
2005AIDS (London)81 citations Open access
Semantic Scholar
Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9
T. Appleby, A. Greenstein, Magdeleine Hung, Albert C. Liclican +10 more
2017Journal of Biological Chemistry78 citations Open access
Semantic Scholar
The A62V and S68G Mutations in HIV-1 Reverse Transcriptase Partially Restore the Replication Defect Associated With the K65R Mutation
E. Svarovskaia, Joy Y. Feng, N. Margot, Florence T. Myrick +7 more
2008Journal of Acquired Immune Deficiency Syndromes65 citations Open access
Semantic Scholar
Effects of the Translocation Status of Human Immunodeficiency Virus Type 1 Reverse Transcriptase on the Efficiency of Excision of Tenofovir
B. Marchand, K. White, John K. Ly, N. Margot +4 more
2007Antimicrobial Agents and Chemotherapy31 citations Open access
Semantic Scholar
Structural, biochemical and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase delta*
J. Somoza, David Koditek, Armando G. Villase, Nor +11 more
201528 citations
Semantic Scholar
The Macroscopic Rate of Nucleic Acid Translocation by Hepatitis C virus Helicase NS3h is Dependent on Both the Sugar and Base Moieties
A. Khaki, Cassandra Field, S. Malik, A. Niedziela-Majka +6 more
2010Journal of Molecular Biology28 citations Open access
Semantic Scholar
Protein Footprinting and X-ray Crystallography Reveal the Interaction of PD-L1 and a Macrocyclic Peptide
Ben Niu, T. Appleby, Ruth Wang, M. Morar +10 more
2019Biochemistry27 citations Open access
Semantic Scholar
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability
Andrew Mulato, E. Lansdon, R. Aoyama, J. Voigt +23 more
2024Antimicrobial Agents and Chemotherapy5 citations Open access
Semantic Scholar
Binding kinetics, potency, and selectivity of the hepatitis C virus NS3 protease inhibitors GS-9256 and vedroprevir.
Ona Barauskas, A. Corsa, Ruth Wang, Scott Hluhanich +5 more
2014Biochimica et Biophysica Acta5 citations
Semantic Scholar
Preparation of HCV NS3 and NS5B Proteins to Support Small‐Molecule Drug Discovery
Magdeleine Hung, Ruth Wang, Xiao-Hong Liu
2011Current Protocols in Pharmacology5 citations
Semantic Scholar
Combination Therapy of Selective MMP9 Inhibitor and JAK Inhibitor Is Effective to Induce Disease Control in Mouse DSS Model of Colitis: 593
Sunhwa Kim, B. Carr, L. Tong, M. Sobczyk +8 more
20160 citations
Semantic Scholar
Nucleic Acid Translocation By Hepatitis C Virus Helicase NS3h Is Dependent on Sugar and Base Moieties
Christopher J. Fischer, A. Khaki, Cassandra Field, S. Malik +6 more
20100 citations Open access
Semantic Scholar
Effects of the Translocation Status of Human Immunodeﬁciency Virus Type 1 Reverse Transcriptase on the Efﬁciency of Excision of Tenofovir (cid:1)
B. Marchand, K. White, John K. Ly, N. Margot +4 more
20070 citations
Semantic Scholar

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