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Andrew Mulato · SciRah

Researcher profile · Semantic Scholar

Andrew Mulato

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Andrew Mulato — researcher profile on SciRah

h-index: 13
Works: 22
Citations: 1,895

Most-cited papers

Clinical targeting of HIV capsid protein with a long-acting small molecule
J. Link, M. Rhee, Winston C. Tse, Jim Zheng +69 more
2020Nature370 citations Open access
Semantic Scholar
Selective Intracellular Activation of a Novel Prodrug of the Human Immunodeficiency Virus Reverse Transcriptase Inhibitor Tenofovir Leads to Preferential Distribution and Accumulation in Lymphatic Tissue
William A. Lee, Gong-Xin He, E. Eisenberg, T. Cihlář +3 more
2005Antimicrobial Agents and Chemotherapy327 citations Open access
Semantic Scholar
NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS, 20(4–7), 641–648 (2001) HUMAN RENAL ORGANIC ANION TRANSPORTER 1 (hOAT1) AND ITS ROLE IN THE NEPHROTOXICITY OF ANTIVIRAL NUCLEOTIDE ANALOGS
T. Cihlář, Edmund S. Ho, Deborah C. Lin, Andrew Mulato
2003253 citations
Semantic Scholar
Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile
M. Tsiang, Gregg S. Jones, J. Goldsmith, Andrew Mulato +14 more
2016Antimicrobial Agents and Chemotherapy248 citations Open access
Semantic Scholar
A Highly Potent Long-Acting Small-Molecule HIV-1 Capsid Inhibitor with Efficacy in a Humanized Mouse Model
S. Yant, Andrew Mulato, Derek Hansen, Winston C. Tse +26 more
2019Nature Medicine140 citations Open access
Semantic Scholar
Nonsteroidal anti-inflammatory drugs efficiently reduce the transport and cytotoxicity of adefovir mediated by the human renal organic anion transporter 1.
Andrew Mulato, Edmund S. Ho, T. Cihlář
2000Journal of Pharmacology and Experimental Therapeutics138 citations Open access
Semantic Scholar
Activation of 9-[(R)-2-[[(S)-[[(S)-1-(Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl]-methoxy]propyl]adenine (GS-7340) and Other Tenofovir Phosphonoamidate Prodrugs by Human Proteases
G. Birkuš, N. Kutty, Gong-Xin He, Andrew Mulato +3 more
2008Molecular Pharmacology103 citations
Semantic Scholar
Suppression of HIV-1 protease inhibitor resistance by phosphonate-mediated solvent anchoring.
T. Cihlář, Gong-Xin He, Xiao-Hong Liu, James M. Chen +9 more
2006Journal of Molecular Biology65 citations
Semantic Scholar
Identification of NK Cell Subpopulations That Differentiate HIV-Infected Subject Cohorts with Diverse Levels of Virus Control
Christopher W. Pohlmeyer, Veronica D. Gonzalez, A. Irrinki, Ricardo Ramírez +11 more
2019Journal of Virology55 citations Open access
Semantic Scholar
Lenacapavir: A Novel, Potent, and Selective First-in-Class Inhibitor of HIV-1 Capsid Function Exhibits Optimal Pharmacokinetic Properties for a Long-Acting Injectable Antiretroviral Agent
Raju Subramanian, Jennifer Tang, Jim Zheng, Bing Lu +16 more
2023Molecular Pharmaceutics52 citations Open access
Semantic Scholar
TLR7 Agonist GS-9620 Is a Potent Inhibitor of Acute HIV-1 Infection in Human Peripheral Blood Mononuclear Cells
Rujuta A. Bam, Derek Hansen, A. Irrinki, Andrew Mulato +5 more
2016Antimicrobial Agents and Chemotherapy52 citations Open access
Semantic Scholar
In Vitro Characterization of GS-8374, a Novel Phosphonate-Containing Inhibitor of HIV-1 Protease with a Favorable Resistance Profile
C. Callebaut, Kirsten M. Stray, Tsai Luong, Matt Williams +15 more
2011Antimicrobial Agents and Chemotherapy34 citations Open access
Semantic Scholar
Discovery of Lenacapavir: First-in-Class Twice-Yearly Capsid Inhibitor for HIV‑1 Treatment and Pre-exposure Prophylaxis
E. Canales, Winston C. Tse, S. Schroeder, Chienhung Chou +43 more
2025Journal of Medicinal Chemistry16 citations Open access
Semantic Scholar
Simulating HIV Breakthrough and Resistance Development During Variable Adherence to Antiretroviral Treatment.
Andrew Mulato, Rima K. Acosta, Silvia Chang, Ross Martin +3 more
2020Journal of Acquired Immune Deficiency Syndromes11 citations
Semantic Scholar
Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence In Vitro
Rima K. Acosta, Michelle L. D'Antoni, Andrew Mulato, S. Yant +2 more
2022Antimicrobial Agents and Chemotherapy9 citations Open access
Semantic Scholar
GS-8374, a Novel Phosphonate HIV Protease Inhibitor with Potent In Vitro Antiretroviral Activity, Low Metabolic Toxicity, and Favorable Resistance Profile
C. Callebaut, Kirsten M. Stray, Tsai Luong, Lian-Hong Xu +6 more
20076 citations
Semantic Scholar
Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability
Andrew Mulato, E. Lansdon, R. Aoyama, J. Voigt +23 more
2024Antimicrobial Agents and Chemotherapy5 citations Open access
Semantic Scholar
Rapid In Vitro Evaluation of Antiretroviral Barrier to Resistance at Therapeutic Drug Levels
Andrew Mulato, Derek Hansen, A. Thielen, D. Porter +5 more
2016AIDS Research and Human Retroviruses5 citations
Semantic Scholar
72Activation of GS-7340 and Other Tenofovir Phosphonoamidate Prodrugs by Human Proteases
G. Birkuš, N. Kutty, Gong-Xin He, Andrew Mulato +3 more
20075 citations
Semantic Scholar
1448. Forgiveness of BIC/FTC/TAF: In Vitro Simulations of Intermittent Poor Adherence Find Limited HIV-1 Breakthrough and High Barrier to Resistance
Andrew Mulato, Rima K. Acosta, S. Yant, T. Cihlář +1 more
2020Open Forum Infectious Diseases2 citations Open access
Semantic Scholar
888. In Vitro Forgiveness of INSTI-Containing Regimens at Drug Concentrations Simulating Variable Adherence
Rima K. Acosta, Andrew Mulato, Michelle L. D'Antoni, S. Yant +2 more
2021Open Forum Infectious Diseases0 citations Open access
Semantic Scholar
Activation of 9-[( R )-2-[[( S )-[[( S )-1-(Isopropoxycarbonyl)ethyl]amino] (GS-7340) and Other Tenofovir Phosphonoamidate Prodrugs by Human Proteases
G. Birkuš, N. Kutty, Gong-Xin He, Andrew Mulato +3 more
20080 citations
Semantic Scholar

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Winston C. Tse×4

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Winston C. Tse — researcher profile on SciRah

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Jim Zheng — researcher profile on SciRah

Rujuta A. Bam×4

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Rujuta A. Bam — researcher profile on SciRah

S. Schroeder×4

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S. Schroeder — researcher profile on SciRah