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C. Tintori · SciRah

Researcher profile · Semantic Scholar

C. Tintori

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C. Tintori — researcher profile on SciRah

h-index: 28
Works: 61
Citations: 1,987

Most-cited papers

Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors.
S. Pasquini, C. Mugnaini, C. Tintori, M. Botta +8 more
2008Journal of Medicinal Chemistry149 citations Open access
Semantic Scholar
Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents
A. Brai, R. Fazi, C. Tintori, Claudio Zamperini +14 more
2016Proceedings of the National Academy of Sciences of the United States of America105 citations Open access
Semantic Scholar
Homology Model-Based Virtual Screening for the Identification of Human Helicase DDX3 Inhibitors
R. Fazi, C. Tintori, A. Brai, L. Botta +4 more
2015Journal of Chemical Information and Modeling92 citations
Semantic Scholar
Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.
F. Carraro, A. Naldini, A. Pucci, Giada. A. Locatelli +13 more
2006Journal of Medicinal Chemistry85 citations Open access
Semantic Scholar
Identification of new aminoacid amides containing the imidazo[2,1-b]benzothiazol-2-ylphenyl moiety as inhibitors of tumorigenesis by oncogenic Met signaling.
Alessandro Furlan, F. Colombo, A. Kover, N. Issaly +14 more
2012European journal of medicinal chemistry78 citations Open access
Semantic Scholar
Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.
M. Radi, E. Dreassi, C. Brullo, Emmanuele Crespan +12 more
2011Journal of Medicinal Chemistry78 citations Open access
Semantic Scholar
Antiproliferative and proapoptotic activities of new pyrazolo[3,4‐d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells
A. Spreafico, S. Schenone, T. Serchi, Maurizio Orlandini +10 more
2008The FASEB Journal72 citations
Semantic Scholar
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines.
S. Schenone, C. Brullo, O. Bruno, F. Bondavalli +7 more
2008European journal of medicinal chemistry67 citations Open access
Semantic Scholar
Combining X-ray crystallography and molecular modeling toward the optimization of pyrazolo[3,4-d]pyrimidines as potent c-Src inhibitors active in vivo against neuroblastoma.
C. Tintori, A. L. Fallacara, M. Radi, Claudio Zamperini +13 more
2015Journal of Medicinal Chemistry65 citations Open access
Semantic Scholar
Exploration of novel thiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors.
Suvi Rajamaki, Anna Innitzer, C. Falciani, C. Tintori +5 more
2009Bioorganic & Medicinal Chemistry Letters57 citations Open access
Semantic Scholar
Synthesis and 3D QSAR of new pyrazolo[3,4-b]pyridines: potent and selective inhibitors of A1 adenosine receptors.
F. Manetti, S. Schenone, F. Bondavalli, C. Brullo +10 more
2005Journal of Medicinal Chemistry55 citations Open access
Semantic Scholar
4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling.
I. Trist, Giulio Nannetti, C. Tintori, A. L. Fallacara +11 more
2016Journal of Medicinal Chemistry53 citations Open access
Semantic Scholar
Targets Looking for Drugs: A Multistep Computational Protocol for the Development of Structure-Based Pharmacophores and Their Applications for Hit Discovery
C. Tintori, V. Corradi, Matteo Magnani, F. Manetti +1 more
2008Journal of Chemical Information and Modeling53 citations
Semantic Scholar
Identification of potent c-Src inhibitors strongly affecting the proliferation of human neuroblastoma cells.
M. Radi, C. Brullo, Emmanuele Crespan, C. Tintori +10 more
2011Bioorganic & Medicinal Chemistry Letters48 citations Open access
Semantic Scholar
Kuwanon‐L as a New Allosteric HIV‐1 Integrase Inhibitor: Molecular Modeling and Biological Evaluation
F. Esposito, C. Tintori, Riccardo Martini, F. Christ +12 more
2015ChemBioChem46 citations
Semantic Scholar
The anti-HIV activity of ADS-J1 targets the HIV-1 gp120.
Mercedes Armand-Ugón, I. Clotet-Codina, C. Tintori, F. Manetti +3 more
2005Virology43 citations Open access
Semantic Scholar
Docking, 3D-QSAR studies and in silico ADME prediction on c-Src tyrosine kinase inhibitors.
C. Tintori, Matteo Magnani, S. Schenone, M. Botta
2009European journal of medicinal chemistry42 citations Open access
Semantic Scholar
Development of an AlphaScreen-Based HIV-1 Integrase Dimerization Assay for Discovery of Novel Allosteric Inhibitors
J. Demeulemeester, C. Tintori, M. Botta, Z. Debyser +1 more
2012Journal of biomolecular screening39 citations Open access
Semantic Scholar
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant.
M. Radi, C. Tintori, Francesca Musumeci, C. Brullo +12 more
2013Journal of Medicinal Chemistry38 citations Open access
Semantic Scholar
Using insights into Pim1 structure to design new anticancer drugs.
S. Schenone, C. Tintori, M. Botta
2010Current pharmaceutical design37 citations
Semantic Scholar
Probing the binding site of abl tyrosine kinase using in situ click chemistry.
Cristina Peruzzotti, Stella Borrelli, M. Ventura, R. Pantano +8 more
2013ACS Medicinal Chemistry Letters36 citations Open access
Semantic Scholar
The Fight against the Influenza A Virus H1N1: Synthesis, Molecular Modeling, and Biological Evaluation of Benzofurazan Derivatives as Viral RNA Polymerase Inhibitors
M. Pagano, D. Castagnolo, M. Bernardini, Anna Lucia Fallacara +8 more
2014ChemMedChem34 citations Open access
Semantic Scholar
'Click' synthesis of a triazole-based inhibitor of Met functions in cancer cells.
F. Colombo, C. Tintori, Alessandro Furlan, Stella Borrelli +7 more
2012Bioorganic & Medicinal Chemistry Letters33 citations Open access
Semantic Scholar
Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family.
C. Tintori, A. Brai, Maria Chiara Dasso Lang, D. Deodato +13 more
2016Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors.
C. Tintori, Giuseppina La Sala, G. Vignaroli, L. Botta +21 more
2015Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Discovery of small molecule HIV-1 integrase dimerization inhibitors.
C. Tintori, J. Demeulemeester, L. Franchi, S. Massa +3 more
2012Bioorganic & Medicinal Chemistry Letters31 citations Open access
Semantic Scholar
High-throughput docking for the identification of new influenza A virus polymerase inhibitors targeting the PA-PB1 protein-protein interaction.
C. Tintori, I. Laurenzana, A. L. Fallacara, U. Kessler +3 more
2014Bioorganic & Medicinal Chemistry Letters30 citations Open access
Semantic Scholar
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides
C. Tintori, G. Iovenitti, E. Ceresola, R. Ferrarese +8 more
2018PLoS ONE29 citations Open access
Semantic Scholar
Natural Product Kuwanon‐L Inhibits HIV‐1 Replication through Multiple Target Binding
Riccardo Martini, F. Esposito, A. Corona, R. Ferrarese +9 more
2017ChemBioChem28 citations Open access
Semantic Scholar
Novel broad spectrum virucidal molecules against enveloped viruses
V. Cagno, C. Tintori, A. Civra, R. Cavalli +7 more
2018PLoS ONE27 citations Open access
Semantic Scholar
Protein-protein interactions and human cellular cofactors as new targets for HIV therapy.
C. Tintori, A. Brai, A. L. Fallacara, R. Fazi +2 more
2014Current opinion in pharmacology (Print)26 citations
Semantic Scholar
Novel Virtual Screening Protocol Based on the Combined Use of Molecular Modeling and Electron-Ion Interaction Potential Techniques To Design HIV-1 Integrase Inhibitors
C. Tintori, F. Manetti, Nevena Veljkovic, Vladimir Perović +7 more
2007Journal of Chemical Information and Modeling25 citations
Semantic Scholar
Toward novel HIV-1 integrase binding inhibitors: molecular modeling, synthesis, and biological studies.
C. Mugnaini, Suvi Rajamaki, C. Tintori, F. Corelli +5 more
2007Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB(2) cannabinoid receptor inverse agonists.
Mojgan Aghazadeh Tabrizi, P. Baraldi, G. Saponaro, A. Moorman +9 more
2013Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Computational studies of the interaction between the HIV‐1 integrase tetramer and the cofactor LEDGF/p75: Insights from molecular dynamics simulations and the Informational spectrum method
C. Tintori, Nevena Veljkovic, V. Veljkovic, M. Botta
2010Proteins: Structure, Function, and Bioinformatics23 citations Open access
Semantic Scholar
Substituted Pyrazolo[3,4‐b]pyridines as Potent A1 Adenosine Antagonists: Synthesis, Biological Evaluation, and Development of an A1 Bovine Receptor Model
T. Tuccinardi, S. Schenone, F. Bondavalli, C. Brullo +10 more
2008ChemMedChem23 citations
Semantic Scholar
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti‐HIV Agents
C. Tintori, I. Laurenzana, F. La Rocca, Federico Falchi +10 more
2013ChemMedChem22 citations
Semantic Scholar
Hck inhibitors as potential therapeutic agents in cancer and HIV infection.
Francesca Musumeci, Silvia Schenone, C. Brullo, Andrea Desogus +2 more
2015Current Medicinal Chemistry21 citations
Semantic Scholar
Inhibition of HIV‐1 Reverse Transcriptase Dimerization by Small Molecules
C. Tintori, A. Corona, F. Esposito, A. Brai +6 more
2016ChemBioChem19 citations Open access
Semantic Scholar
Investigation on the sucrose binding pocket of HIV-1 Integrase by molecular dynamics and synergy experiments.
C. Tintori, F. Esposito, F. Morreale, Riccardo Martini +2 more
2015Bioorganic & Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
Insight into the Allosteric Inhibition of Abl Kinase
A. L. Fallacara, C. Tintori, M. Radi, S. Schenone +1 more
2014Journal of Chemical Information and Modeling19 citations
Semantic Scholar
A Combination Strategy to Inhibit Pim‐1: Synergism between Noncompetitive and ATP‐Competitive Inhibitors
M. Mori, C. Tintori, Robert Christopher, M. Radi +10 more
2013ChemMedChem19 citations
Semantic Scholar
A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia
I. Laurenzana, A. Caivano, S. Trino, L. De Luca +13 more
2016OncoTarget18 citations Open access
Semantic Scholar
Bcr-Abl tyrosine kinase inhibitors: a patent review
Andrea Desogus, S. Schenone, C. Brullo, C. Tintori +1 more
2015Expert Opinion on Therapeutic Patents16 citations
Semantic Scholar
A Combination of Molecular Dynamics and Docking Calculations to Explore the Binding Mode of ADS-J1, a Polyanionic Compound Endowed with Anti-HIV-1 Activity
F. Manetti, C. Tintori, Mercedes Armand-Ugón, I. Clotet-Codina +4 more
2006Journal of Chemical Information and Modeling13 citations
Semantic Scholar
2-Aminothiazolones as Anti-HIV Agents That Act as gp120-CD4 Inhibitors
M. Tiberi, C. Tintori, E. Ceresola, R. Fazi +11 more
2014Antimicrobial Agents and Chemotherapy12 citations Open access
Semantic Scholar
A Versatile and Practical Synthesis toward the Development of Novel HIV‐1 Integrase Inhibitors
Marta Rinaldi, C. Tintori, L. Franchi, G. Vignaroli +7 more
2011ChemMedChem11 citations Open access
Semantic Scholar
Structure–Activity Relationships on Cinnamoyl Derivatives as Inhibitors of p300 Histone Acetyltransferase
V. N. Madia, R. Benedetti, M. L. Barreca, Liza Ngo +14 more
2017ChemMedChem10 citations Open access
Semantic Scholar
Computational Studies Identifying Entry Inhibitor Scaffolds Targeting the Phe 43 Cavity of HIV‐1 gp120
C. Tintori, Manikandan Selvaraj, R. Badia, B. Clotet +2 more
2013ChemMedChem10 citations
Semantic Scholar
Pharmacophoric models and 3D QSAR studies of the adenosine receptor ligands.
C. Tintori, F. Manetti, M. Botta
2010Current Topics in Medicinal Chemistry10 citations
Semantic Scholar

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