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J. Elias · SciRah

Researcher profile · Semantic Scholar

J. Elias

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J. Elias — researcher profile on SciRah

h-index: 85
Works: 315
Citations: 27K

Most-cited papers

Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2
Chuan H. He, C. Lee, C. Dela Cruz, Chang-Min Lee +12 more
2013Cell Reports284 citations Open access
Semantic Scholar
Chitinase 3–like 1 Suppresses Injury and Promotes Fibroproliferative Responses in Mammalian Lung Fibrosis
Yang Zhou, Hong-Hua Peng, Huan-Xing Sun, Xue-Yang Peng +16 more
2014Science Translational Medicine186 citations Open access
Semantic Scholar
Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer Disease pathogenesis
Brian V. Lananna, Celia A. McKee, M. King, J. Del-Aguila +10 more
2020Science Translational Medicine178 citations Open access
Semantic Scholar
Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis
Avignat S. Patel, J. Song, S. Chu, Kenji Mizumura +8 more
2015PLoS ONE172 citations Open access
Semantic Scholar
IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses
Chang-Min Lee, Chuan H. He, Adel M. Nour, Yang Zhou +9 more
2016Nature Communications128 citations Open access
Semantic Scholar
Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis.
R. Reilkoff, Hong-Hua Peng, L. Murray, Xue-Yang Peng +9 more
2013American Journal of Respiratory and Critical Care Medicine126 citations Open access
Semantic Scholar
Potential Role of Chitinase-3-like Protein 1 (CHI3L1/YKL-40) in Neurodegeneration and Alzheimer’s Disease
Kevin Connolly, Mikael Lehoux, R. O'Rourke, Benedetta Assetta +4 more
2022Alzheimer's & Dementia120 citations Open access
Semantic Scholar
Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function.
I. Schmidt, I. Hall, S. Kale, Sik Lee +8 more
2013Journal of the American Society of Nephrology112 citations Open access
Semantic Scholar
Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis
Do-Hyun Kim, Hong-Jai Park, Sang-Ho Lim, Ja-Hyun Koo +9 more
2018Nature Communications106 citations Open access
Semantic Scholar
Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-β1 Signaling
C. Lee, E. Herzog, Farida Ahangari, Yang Zhou +7 more
2012Journal of Immunology103 citations Open access
Semantic Scholar
Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis
S. Ryter, I. Rosas, C. Owen, F. Martinez +4 more
2018Annals of the American Thoracic Society98 citations Open access
Semantic Scholar
Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9
Daren Low, R. Subramaniam, Li Lin, T. Aomatsu +8 more
2015OncoTarget92 citations Open access
Semantic Scholar
Role of Chitinase 3-like-1 and Semaphorin 7a in Pulmonary Melanoma Metastasis
B. Ma, E. Herzog, C. Lee, Xue-Yang Peng +8 more
2014Cancer Research87 citations Open access
Semantic Scholar
Chitinase 3-like-1 regulates both visceral fat accumulation and asthma-like Th2 inflammation.
Farida Ahangari, A. Sood, B. Ma, S. Takyar +6 more
2015American Journal of Respiratory and Critical Care Medicine82 citations Open access
Semantic Scholar
Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis
L. Murray, D. Habiel, M. Hohmann, A. Camelo +18 more
2017JCI Insight79 citations Open access
Semantic Scholar
Suppression of NLRX1 in chronic obstructive pulmonary disease.
Min-Jong Kang, C. Yoon, Bo Hye Kim, Chang-Min Lee +14 more
2015Journal of Clinical Investigation74 citations Open access
Semantic Scholar
Fatty acid binding protein 4 regulates VEGF-induced airway angiogenesis and inflammation in a transgenic mouse model: implications for asthma.
E. Ghelfi, Chen-Wei Yu, H. Elmasri, Matthew Terwelp +7 more
2013American Journal of Pathology74 citations Open access
Semantic Scholar
Chitinase 3-like-1 and its receptors in Hermansky-Pudlak syndrome-associated lung disease.
Yang Zhou, Chuan H. He, E. Herzog, Xue-Yang Peng +8 more
2015Journal of Clinical Investigation71 citations Open access
Semantic Scholar
Modifiers of TGF-β1 effector function as novel therapeutic targets of pulmonary fibrosis
Chang-Min Lee, Jin Wook Park, Won-Kyung Cho, Yang Zhou +5 more
2014The Korean Journal of Internal Medicine70 citations Open access
Semantic Scholar
VEGF controls lung Th2 inflammation via the miR-1–Mpl (myeloproliferative leukemia virus oncogene)–P-selectin axis
S. Takyar, H. Vasavada, Jian-ge Zhang, Farida Ahangari +5 more
2013Journal of Experimental Medicine70 citations Open access
Semantic Scholar
Chitinase 3‐like 1 drives allergic skin inflammation via Th2 immunity and M2 macrophage activation
Eun Ji Kwak, Jung-Ye-On Hong, M. N. Kim, Soo-Yeon Kim +7 more
2019Clinical and Experimental Allergy63 citations Open access
Semantic Scholar
CHI3L1 regulates PD-L1 and anti-CHI3L1-PD-1 antibody elicits synergistic antitumor responses.
B. Ma, B. Akosman, S. Kamle, Chang-Min Lee +4 more
2021Journal of Clinical Investigation61 citations Open access
Semantic Scholar
AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites
L. Kim, Rimpei Morita, Y. Kobayashi, S. Eisenbarth +4 more
2015Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
Plasma Levels of the Proinflammatory Chitin‐Binding Glycoprotein YKL‐40, Variation in the Chitinase 3‐Like 1 Gene (CHI3L1), and Incident Cardiovascular Events
P. Ridker, D. Chasman, L. Rose, J. Loscalzo +1 more
2014Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease55 citations Open access
Semantic Scholar
In the Shadow of Fibrosis: Innate Immune Suppression Mediated by Transforming Growth Factor-β.
B. Thomas, Keiko Kan-o, K. Loveland, J. Elias +1 more
2016American Journal of Respiratory Cell and Molecular Biology51 citations
Semantic Scholar
IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension.
Won-Kyung Cho, Chang-Min Lee, Min-Jong Kang, Yan Huang +7 more
2013American Journal of Physiology - Lung cellular and Molecular Physiology48 citations Open access
Semantic Scholar
Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis*
P. Yoon, Jin Wook Park, Chang-Min Lee, Sung Hwan Kim +16 more
2016Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Role of Chitinase 3-Like-1 in Interleukin-18-Induced Pulmonary Type 1, Type 2, and Type 17 Inflammation; Alveolar Destruction; and Airway Fibrosis in the Murine Lung.
Min-Jong Kang, C. Yoon, Milang Nam, Do-Hyun Kim +3 more
2015American Journal of Respiratory Cell and Molecular Biology47 citations Open access
Semantic Scholar
Proteome-Wide Analysis using SOMAscan Identifies and Validates Chitinase-3-Like Protein 1 as a Risk and Disease Marker of Delirium Among Older Adults Undergoing Major Elective Surgery.
Sarinnapha M. Vasunilashorn, S. Dillon, N. Chan, T. Fong +10 more
2021The journals of gerontology. Series A, Biological sciences and medical sciences46 citations Open access
Semantic Scholar
Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization
Eun Gyul Kim, M. N. Kim, Jung-Ye-On Hong, Jae Woo Lee +6 more
2020Allergy Asthma and Immunology Research45 citations Open access
Semantic Scholar
Breast Regression Protein-39/Chitinase 3-Like 1 Promotes Renal Fibrosis after Kidney Injury via Activation of Myofibroblasts.
T. A. Montgomery, Leyuan Xu, S. Mason, Amirtha V. Chinnadurai +3 more
2017Journal of the American Society of Nephrology45 citations Open access
Semantic Scholar
Chitinase 3-like 1 synergistically activates IL6-mediated STAT3 phosphorylation in intestinal epithelial cells in murine models of infectious colitis
H. Tran, In-Ah Lee, Daren Low, A. Kamba +5 more
2014Inflammatory Bowel Diseases41 citations Open access
Semantic Scholar
Urine YKL-40 is associated with progressive acute kidney injury or death in hospitalized patients
I. Hall, Edward P. Stern, L. Cantley, J. Elias +1 more
2014BMC Nephrology38 citations Open access
Semantic Scholar
Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19
S. Kamle, B. Ma, Chuan H. He, B. Akosman +11 more
2021JCI Insight37 citations Open access
Semantic Scholar
Chitinase 3-like-1 contributes to acetaminophen-induced liver injury by promoting hepatic platelet recruitment
Shan Zhao, Lei-Ke Li, C. Atkins, Meng Wang +13 more
2021bioRxiv34 citations Open access
Semantic Scholar
Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3
Chang-Min Lee, Chuan H. He, Jin Wook Park, Jae Hyun Lee +15 more
2019Life Science Alliance34 citations Open access
Semantic Scholar
Lung Endothelial MicroRNA‐1 Regulates Tumor Growth and Angiogenesis
Asawari Korde, Lei Jin, Jian-ge Zhang, Anuradha Ramaswamy +12 more
2017American Journal of Respiratory and Critical Care Medicine33 citations Open access
Semantic Scholar
Chitinase 3‐like 1 protein plays a critical role in respiratory syncytial virus‐induced airway inflammation
Min Jung Kim, D. Shim, Hye-Ran Cha, Kuk-Young Moon +8 more
2018Allergy. European Journal of Allergy and Clinical Immunology32 citations Open access
Semantic Scholar
Laminin α1 is a genetic modifier of TGF-β1-stimulated pulmonary fibrosis.
Chang-Min Lee, S. Cho, Won-Kyung Cho, Jin Wook Park +7 more
2018JCI Insight31 citations Open access
Semantic Scholar
CHI3L1 enhances melanoma lung metastasis via regulation of T cell co-stimulators and CTLA-4/B7 axis
B. Ma, S. Kamle, B. Akosman, H. Khan +3 more
2022bioRxiv30 citations Open access
Semantic Scholar
N-Glycosylation Regulates Chitinase 3-like-1 and IL-13 Ligand Binding to IL-13 Receptor α2.
Chuan H. He, C. Lee, B. Ma, S. Kamle +2 more
2020American Journal of Respiratory Cell and Molecular Biology30 citations Open access
Semantic Scholar
YKL-40, a chitinase-like protein at the intersection of inflammation and remodeling.
C. Lee, C. Dela Cruz, E. Herzog, S. M. Rosenberg +2 more
2012American Journal of Respiratory and Critical Care Medicine29 citations
Semantic Scholar
Club cell-specific role of programmed cell death 5 in pulmonary fibrosis
Soo-yeon Park, Jung-Ye-On Hong, Soo-Ye-On Lee, Seung-Hyun Lee +9 more
2021Nature Communications28 citations Open access
Semantic Scholar
Cytokine ranking via mutual information algorithm correlates cytokine profiles with presenting disease severity in patients infected with SARS-CoV-2
Kelsey E. Huntington, Anna D. Louie, C. Lee, J. Elias +2 more
2021eLife28 citations Open access
Semantic Scholar
Future Research Directions in Asthma
W. Busse, S. Banks-Schlegel, Patricia J. Noel, H. Ortega +2 more
201227 citations
Semantic Scholar
Matrix metalloproteinase-targeted imaging of lung inflammation and remodeling
R. Golestani, Mahmoud Razavian, Yun-Peng Ye, Jia-Sheng Zhang +8 more
2016Journal of Nuclear Medicine26 citations Open access
Semantic Scholar
Increased Plasma YKL-40/Chitinase-3-Like-Protein-1 Is Associated with Endothelial Dysfunction in Obstructive Sleep Apnea
B. Jafari, J. Elias, V. Mohsenin
2014PLoS ONE25 citations Open access
Semantic Scholar
Chitinase-like proteins in lung injury, repair, and metastasis.
C. Lee, C. Dela Cruz, B. Ma, Farida Ahangari +4 more
2012Proceedings of the American Thoracic Society25 citations Open access
Semantic Scholar
Regulation and Role of Chitotriosidase during Lung Infection with Klebsiella pneumoniae
L. Sharma, A. Amick, Swathy O. Vasudevan, S. Lee +9 more
2018Journal of Immunology24 citations Open access
Semantic Scholar
Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection
Koen Breyne, Jonas Steenbrugge, K. Demeyere, C. Lee +5 more
2018Frontiers in Immunology24 citations Open access
Semantic Scholar

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