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I. Rosas · SciRah

Researcher profile · Semantic Scholar

I. Rosas

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I. Rosas — researcher profile on SciRah

h-index: 71
Works: 273
Citations: 18K

Most-cited papers

Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia
I. Rosas, N. Bräu, Michael Waters, R. Go +19 more
2021New England Journal of Medicine853 citations Open access
Semantic Scholar
Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis.
B. Moss, S. Ryter, I. Rosas
2021Annual Review of Pathology724 citations
Semantic Scholar
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis
T. Adams, J. Schupp, S. Poli, Ehab A. Ayaub +14 more
2020Science Advances707 citations Open access
Semantic Scholar
Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary Fibrosis
T. Adams, J. Schupp, S. Poli, Ehab A. Ayaub +14 more
2019bioRxiv387 citations Open access
Semantic Scholar
Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung
J. Schupp, T. Adams, C. Cosme, M. S. Raredon +26 more
2020bioRxiv337 citations Open access
Semantic Scholar
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C. Muus, M. Luecken, G. Eraslan, L. Sikkema +110 more
2021Nature Medicine326 citations Open access
Semantic Scholar
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells
C. Muus, M. Luecken, G. Eraslan, Avinash Waghray +100 more
2020bioRxiv255 citations Open access
Semantic Scholar
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases
I. Korsunsky, Kevin Wei, M. Pohin, E. Kim +31 more
2021bioRxiv222 citations Open access
Semantic Scholar
Methotrexate and rheumatoid arthritis associated interstitial lung disease
P. Juge, Joyce S. Lee, J. Lau, Letícia Kawano-Dourado +51 more
2020European Respiratory Journal221 citations Open access
Semantic Scholar
ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension
Lai Yung, Peiran Yang, S. Joshi, Z. Augur +16 more
2020Science Translational Medicine219 citations Open access
Semantic Scholar
Characterization of the COPD alveolar niche using single-cell RNA sequencing
M. Sauler, J. McDonough, T. Adams, N. Kothapalli +22 more
2022Nature Communications203 citations Open access
Semantic Scholar
Single-cell connectomic analysis of adult mammalian lungs
M. S. Raredon, T. Adams, Yasir Suhail, J. Schupp +14 more
2019Science Advances193 citations Open access
Semantic Scholar
Imaging Patterns are Associated with Interstitial Lung Abnormality Progression and Mortality.
R. Putman, G. Gudmundsson, G. Axelsson, Tomoyuki Hida +16 more
2019American Journal of Respiratory and Critical Care Medicine184 citations Open access
Semantic Scholar
Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-controlled, phase 2 study.
J. Solomon, S. Danoff, F. Woodhead, S. Hurwitz +24 more
2022The Lancet Respiratory Medicine159 citations Open access
Semantic Scholar
Expert consensus on the management of systemic sclerosis-associated interstitial lung disease
Franck Rahaghi, V. Hsu, R. Kaner, M. Mayes +20 more
2023Respiratory Research127 citations Open access
Semantic Scholar
Association of triglyceride-glucose index and lung health: a population-based study.
T. Wu, A. Fawzy, E. Brigham, M. McCormack +3 more
2021Chest117 citations Open access
Semantic Scholar
Tocilizumab and remdesivir in hospitalized patients with severe COVID-19 pneumonia: a randomized clinical trial
I. Rosas, G. Diaz, R. Gottlieb, S. Lobo +17 more
2021Intensive Care Medicine112 citations Open access
Semantic Scholar
Palmitic Acid-Rich High Fat Diet Exacerbates Experimental Pulmonary Fibrosis by Modulating Endoplasmic Reticulum Stress.
S. Chu, J. Villalba, Xiaoliang Liang, K. Xiong +10 more
2019American Journal of Respiratory Cell and Molecular Biology104 citations Open access
Semantic Scholar
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis.
T. Adams, J. Schupp, S. Poli, Ehab A. Ayaub +14 more
2020Science Advances99 citations Open access
Semantic Scholar
Overlap of Genetic Risk Between Interstitial Lung Abnormalities and Idiopathic Pulmonary Fibrosis.
B. Hobbs, R. Putman, T. Araki, M. Nishino +38 more
2019American Journal of Respiratory and Critical Care Medicine93 citations Open access
Semantic Scholar
Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models
Suraj U. Hettiarachchi, Yen-Hsing Li, Jyoti Roy, Fenghua Zhang +9 more
2020Science Translational Medicine84 citations
Semantic Scholar
Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis
Fenghua Zhang, Ehab A. Ayaub, Bingbing Wang, E. Puchulu-Campanella +11 more
2020EMBO Molecular Medicine73 citations Open access
Semantic Scholar
Interstitial Lung Disease in Relatives of Patients with Pulmonary Fibrosis.
G. Hunninghake, L. Quesada-Arias, N. Carmichael, J. M. Martinez Manzano +12 more
2020American Journal of Respiratory and Critical Care Medicine71 citations Open access
Semantic Scholar
Shorter telomere length following lung transplantation is associated with clinically significant leukopenia and decreased chronic lung allograft dysfunction-free survival
A. Courtwright, Anthony M Lamattina, Mai Takahashi, A. Trindade +6 more
2020ERJ Open Research59 citations Open access
Semantic Scholar
Single Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis
J. Schupp, S. Khanal, Jose L. Gomez, M. Sauler +12 more
2020medRxiv59 citations Open access
Semantic Scholar
Baseline Characteristics and Progression of a Spectrum of Interstitial Lung Abnormalities and Disease in Rheumatoid Arthritis.
Letícia Kawano-Dourado, T. Doyle, K. Bonfiglioli, M. Sawamura +10 more
2020Chest57 citations Open access
Semantic Scholar
Nintedanib and immunomodulatory therapies in progressive fibrosing interstitial lung diseases
V. Cottin, L. Richeldi, I. Rosas, M. Otaola +8 more
2021Respiratory Research56 citations Open access
Semantic Scholar
Comparative Profiling of Serum Protein Biomarkers in Rheumatoid Arthritis–Associated Interstitial Lung Disease and Idiopathic Pulmonary Fibrosis
D. Kass, M. Nouraie, M. Glassberg, N. Ramreddy +13 more
2020Arthritis & Rheumatology50 citations
Semantic Scholar
The Design and Rationale of the Trail1 Trial: A Randomized Double-Blind Phase 2 Clinical Trial of Pirfenidone in Rheumatoid Arthritis-Associated Interstitial Lung Disease
J. Solomon, S. Danoff, H. Goldberg, F. Woodhead +10 more
2019Advances in Therapy50 citations
Semantic Scholar
Understanding post-COVID-19 interstitial lung disease (ILD): a new fibroinflammatory disease entity
P. Mehta, I. Rosas, M. Singer
2022Intensive Care Medicine48 citations Open access
Semantic Scholar
CD148 Deficiency in Fibroblasts Promotes the Development of Pulmonary Fibrosis.
K. Tsoyi, Xiaoliang Liang, G. De Rossi, S. Ryter +14 more
2021American Journal of Respiratory and Critical Care Medicine48 citations Open access
Semantic Scholar
Detection and Early Referral of Patients With Interstitial Lung Abnormalities
G. Hunninghake, J. Goldin, M. Kadoch, J. Kropski +16 more
2021Chest43 citations Open access
Semantic Scholar
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity
L. Bùi, N. Winters, M. Chung, Chitra Joseph +17 more
2020Nature Communications42 citations Open access
Semantic Scholar
A Phase IIb Randomized Study of an Anti-αvβ6 Monoclonal Antibody in Idiopathic Pulmonary Fibrosis.
G. Raghu, M. Mouded, D. Chambers, F. Martinez +17 more
2022American Journal of Respiratory and Critical Care Medicine41 citations
Semantic Scholar
Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial (COVACTA)
I. Rosas, N. Bräu, Michael Waters, R. Go +33 more
2022EClinicalMedicine36 citations Open access
Semantic Scholar
Fibroblasts positive for meflin have anti-fibrotic properties in pulmonary fibrosis
Y. Nakahara, N. Hashimoto, K. Sakamoto, A. Enomoto +16 more
2021European Respiratory Journal35 citations
Semantic Scholar
Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3
Chang-Min Lee, Chuan H. He, Jin Wook Park, Jae Hyun Lee +15 more
2019Life Science Alliance34 citations Open access
Semantic Scholar
Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and Acute Respiratory Distress Syndrome
J. Villalba, Caroline F. Hilburn, Michelle A. Garlin, Grant A Elliott +40 more
2022American Journal of Respiratory and Critical Care Medicine28 citations Open access
Semantic Scholar
Prognostic and Predictive Biomarkers in Patients With Coronavirus Disease 2019 Treated With Tocilizumab in a Randomized Controlled Trial*
Jennifer A. Tom, M. Bao, L. Tsai, Aditi Qamra +19 more
2021Critical Care Medicine28 citations Open access
Semantic Scholar
Suspected Interstitial Lung Disease in COPDGene.
J. A. Rose, A. Menon, T. Hino, Akinori Hata +13 more
2022American Journal of Respiratory and Critical Care Medicine27 citations
Semantic Scholar
Interstitial lung abnormalities are associated with decreased mean telomere length
R. Putman, G. Axelsson, S. Ash, J. Sanders +21 more
2022European Respiratory Journal24 citations Open access
Semantic Scholar
Serum Proteomic Profiling of Rheumatoid Arthritis-Interstitial Lung Disease With a Comparison to Idiopathic Pulmonary Fibrosis
Xiaoping Wu, Yu-Mi Jeong, S. P. de Frias, I. Easthausen +20 more
2022Thorax21 citations Open access
Semantic Scholar
TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF
Lan Wang, Wen-Yu Zhao, Cong Xia, Zhong-Zheng Li +6 more
2022International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Esomeprazole attenuates inflammatory and fibrotic response in lung cells through the MAPK/Nrf2/HO1 pathway
A. Ebrahimpour, Min Wang, Li Li, A. Jegga +8 more
2021Journal of Inflammation19 citations Open access
Semantic Scholar
Syndecan-2 regulates PAD2 to exert antifibrotic effects on RA-ILD fibroblasts
K. Tsoyi, A. Esposito, Bo Sun, R. Bowen +15 more
2022Scientific Reports18 citations Open access
Semantic Scholar
Metabolic Changes in Lymphangioleiomyomatosis Patients Treated with Sirolimus and Hydroxychloroquine.
Yan Tang, S. El-Chemaly, A. Taveira-Dasilva, H. Goldberg +5 more
2019Chest18 citations Open access
Semantic Scholar
GWAS Functional Variant rs2076295 Regulates Desmoplakin (DSP) Expression in Airway Epithelial Cells.
Y. Hao, S. Bates, H. Mou, J. Yun +15 more
2020American Journal of Respiratory and Critical Care Medicine17 citations Open access
Semantic Scholar
PAD2-mediated citrullination of Fibulin-5 promotes elastogenesis
Bo Sun, Beverly Tomita, A. Salinger, R. Tilvawala +8 more
2021Matrix Biology15 citations Open access
Semantic Scholar
Psychological impact of genetic and clinical screening for pulmonary fibrosis on asymptomatic first-degree relatives of affected individuals
N. Carmichael, J. M. Martinez Manzano, L. Quesada-Arias, Sergio de Frías Poli +13 more
2021Thorax15 citations Open access
Semantic Scholar
Mesenchymal Stromal Cell-Derived Syndecan-2 Regulates the Immune Response During Sepsis to Foster Bacterial Clearance and Resolution of Inflammation
Junwen Han, Yuan-Yuan Shi, G. Willis, J. Imani +13 more
2021The FEBS Journal15 citations Open access
Semantic Scholar

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S. Poli×13
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S. Poli — researcher profile on SciRah
T. Adams×11
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T. Adams — researcher profile on SciRah
J. Schupp×10
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J. Schupp — researcher profile on SciRah
S. El-Chemaly×10
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×9

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Ehab A. Ayaub — researcher profile on SciRah

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B. Raby — researcher profile on SciRah

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N. Kaminski — researcher profile on SciRah

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S. Chu — researcher profile on SciRah

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G. Washko — researcher profile on SciRah

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H. Hatabu — researcher profile on SciRah

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G. Hunninghake — researcher profile on SciRah

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K. Tsoyi — researcher profile on SciRah