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E. Park · SciRah

Researcher profile · Semantic Scholar

E. Park

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E. Park — researcher profile on SciRah

h-index: 25
Works: 90
Citations: 3,034

Most-cited papers

Mechanisms of Sec61/SecY-mediated protein translocation across membranes.
E. Park, T. Rapoport
2012Annual Review of Biophysics373 citations
Semantic Scholar
Structural and Mechanistic Insights into Protein Translocation.
T. Rapoport, Long Li, E. Park
2017Annual Review of Cell and Developmental Biology310 citations Open access
Semantic Scholar
Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism
Byung-Gil Lee, E. Park, Kyung-Eun Lee, H. Jeon +5 more
2010Nature Structural &Molecular Biology222 citations
Semantic Scholar
Crystal structure of a substrate-engaged SecY protein-translocation channel
Long Li, E. Park, Jing-Jing J. Ling, J. Ingram +2 more
2016Nature182 citations Open access
Semantic Scholar
Structure of the SecY channel during initiation of protein translocation
E. Park, J. Ménétret, J. Gumbart, S. Ludtke +4 more
2013Nature168 citations Open access
Semantic Scholar
Cryo-EM structure of the mitochondrial protein-import channel TOM complex at near-atomic resolution
K. Tucker, E. Park
2019Nature Structural & Molecular Biology160 citations Open access
Semantic Scholar
Structure of a CLC chloride ion channel by cryo-electron microscopy
E. Park, E. Campbell, R. MacKinnon
2016Nature142 citations Open access
Semantic Scholar
Lysosomal GPCR-like Protein LYCHOS Signals Cholesterol Sufficiency to mTORC1
Hijai R. Shin, Y. R. Citron, Lei Wang, Laura Tribouillard +16 more
2022Science125 citations Open access
Semantic Scholar
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase
Michael J. McKenna, S. Sim, A. Ordureau, Lianjie Wei +3 more
2020Science123 citations Open access
Semantic Scholar
Preserving the membrane barrier for small molecules during bacterial protein translocation
E. Park, T. Rapoport
2011Nature112 citations Open access
Semantic Scholar
Ribosome binding of a single copy of the SecY complex: implications for protein translocation.
J. Ménétret, Julia Schaletzky, W. Clemons, Andrew R Osborne +8 more
2007Molecules and Cells111 citations Open access
Semantic Scholar
Single copies of Sec61 and TRAP associate with a non-translating mammalian ribosome
J. Ménétret, R. Hegde, Mike Aguiar, S. Gygi +3 more
2008Structure105 citations Open access
Semantic Scholar
Role of the GYVG Pore Motif of HslU ATPase in Protein Unfolding and Translocation for Degradation by HslV Peptidase*
E. Park, Young Min Rho, O. Koh, Sung Won Ahn +7 more
2005Journal of Biological Chemistry98 citations Open access
Semantic Scholar
Structure of the CLC-1 chloride channel from Homo sapiens
E. Park, R. MacKinnon
2018eLife84 citations Open access
Semantic Scholar
Structural basis of mitochondrial protein import by the TIM23 complex
S. Sim, Yuanyuan Chen, Diane L. Lynch, J. Gumbart +1 more
2023Nature82 citations Open access
Semantic Scholar
Structure of the posttranslational Sec protein-translocation channel complex from yeast
S. Itskanov, E. Park
2018Science82 citations Open access
Semantic Scholar
Structure of the substrate-engaged SecA-SecY protein translocation machine
Cheng-Ying Ma, Xiaofei Wu, Dongjie Sun, E. Park +4 more
2019Nature Communications71 citations Open access
Semantic Scholar
A common mechanism of Sec61 translocon inhibition by small molecules
S. Itskanov, Laurie Wang, T. Junne, R. Sherriff +7 more
2022bioRxiv69 citations Open access
Semantic Scholar
Mechanism of Protein Translocation by the Sec61 Translocon Complex.
S. Itskanov, E. Park
2022Cold Spring Harbor Perspectives in Biology59 citations
Semantic Scholar
Structural basis of SspB-tail recognition by the zinc binding domain of ClpX.
E. Park, Byung-Gil Lee, S. Hong, Hyung-Wook Kim +2 more
2007Journal of Molecular Biology59 citations
Semantic Scholar
Stepwise gating of the Sec61 protein-conducting channel by Sec63 and Sec62
S. Itskanov, Katie M Kuo, J. Gumbart, E. Park
2021Nature Structural & Molecular Biology55 citations Open access
Semantic Scholar
Bacterial protein translocation requires only one copy of the SecY complex in vivo
E. Park, T. Rapoport
2012Journal of Cell Biology52 citations Open access
Semantic Scholar
Structural basis of polyamine transport by human ATP13A2 (PARK9)
S. Sim, Sören von Bülow, G. Hummer, E. Park
2021bioRxiv50 citations Open access
Semantic Scholar
Crystal structure of the Bowman-Birk inhibitor from barley seeds in ternary complex with porcine trypsin.
E. Park, Jeom-A Kim, Hyung-Wook Kim, Y. S. Kim +1 more
2004Journal of Molecular Biology31 citations
Semantic Scholar
Probing the Functional Importance of the Hexameric Ring Structure of RNase PH*
Jung Choi, E. Park, J. H. Kim, S. Chang +1 more
2004Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Binding of MG132 or Deletion of the Thr Active Sites in HslV Subunits Increases the Affinity of HslV Protease for HslU ATPase and Makes This Interaction Nucleotide-independent*
E. Park, J. Lee, S. Eom, J. Seol +1 more
2008Journal of Biological Chemistry19 citations Open access
Semantic Scholar
P5-ATPases: Structure, substrate specificities, and transport mechanisms.
S. Sim, E. Park
2023Current Opinion in Structural Biology18 citations Open access
Semantic Scholar
HslVU ATP-dependent Protease Utilizes Maximally Six among Twelve Threonine Active Sites during Proteolysis*
J. Lee, E. Park, Minjee Jeong, Y. Jeon +3 more
2009Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Biochemical and structural characterization of 5'-methylthioadenosine nucleosidases from Arabidopsis thaliana.
E. Park, Woo-Suk Choi, Seung-ick Oh, Kyung-nam Kim +2 more
2009Biochemical and Biophysical Research Communications - BBRC9 citations
Semantic Scholar
Structural alteration in the pore motif of the bacterial 20S proteasome homolog HslV leads to uncontrolled protein degradation.
E. Park, J. Lee, H. M. Yoo, B. Ha +5 more
2013Journal of Molecular Biology6 citations
Semantic Scholar
Diffraction Structural Biology Synchrotron Radiation a Degradation Signal Recognition in Prokaryotes
E. Park, H. Song
6 citations
Semantic Scholar
Discovery of a Highly Potent and Broadly Effective EGFR and HER2 Exon 20 Insertion Mutant Inhibitor
E. Park, M. Eck
20184 citations
Semantic Scholar
Sec61/SecY-Mediated Protein Translocation Across Membranes
E. Park, T. Rapoport
20123 citations
Semantic Scholar
Nucleotide triphosphates inhibit the degradation of unfolded proteins by HslV peptidase.
J. Lee, E. Park, O. Bang, S. Eom +3 more
2007Molecules and Cells3 citations Open access
Semantic Scholar
Crystal structure of 5'-methylthioadenosine nucleosidase from Arabidopsis thaliana
E. Park, Byung-Gil Lee, B. Jeong, H. Song
20062 citations
Semantic Scholar
Crystal structures of EGFR in complex with Mig6
E. Park, Nayoung K. D. Kim, Z. Yi, Ahye Cho +10 more
20151 citations
Semantic Scholar
Cryo-EM and photocrosslinking studies reveal the mechanism of mitochondrial protein import by the TIM complex.
E. Park
2023Biophysical Journal0 citations Open access
Semantic Scholar
Cryo-EM structure of the Sec complex from T. lanuginosus, Sec62-lacking mutant (Delta Sec62)
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double mutant, class without Sec62
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class without Sec62
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation 1 (C1)
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from yeast, Sec63 FN3 and residues 210-216 mutated
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class without Sec62
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 1 (C1)
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation 2 (C2)
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62, conformation 2 (C2)
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from T. lanuginosus, wild-type, class without Sec62
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Cryo-EM structure of the Sec complex from T. lanuginosus, wild-type, class with Sec62, plug-open conformation
S. Itskanov, E. Park
20210 citations
Semantic Scholar
Crystal structure of the BRAF:MEK1 kinases in complex with AMPPNP and CH5126766
K. Li, G. G. Del-Pino, B. Ha, E. Park +1 more
20200 citations
Semantic Scholar
Crystal structure of the BRAF:MEK1 kinases in complex with AMPPNP and Cobimetinib
K. Li, G. G. Del-Pino, B. Ha, E. Park +1 more
20200 citations
Semantic Scholar

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