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W. Clemons · SciRah

Researcher profile · Semantic Scholar

W. Clemons

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W. Clemons — researcher profile on SciRah

h-index: 24
Works: 106
Citations: 3,422

Most-cited papers

Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY
Kurt S. Cannon, E. Or, W. Clemons, Y. Shibata +1 more
2005Journal of Cell Biology178 citations Open access
Semantic Scholar
A large conformational change of the translocation ATPase SecA.
Andrew R Osborne, W. Clemons, T. Rapoport
2004Proceedings of the National Academy of Sciences of the United States of America161 citations Open access
Semantic Scholar
Ribosome binding of a single copy of the SecY complex: implications for protein translocation.
J. Ménétret, Julia Schaletzky, W. Clemons, Andrew R Osborne +8 more
2007Molecules and Cells111 citations Open access
Semantic Scholar
Bag6 complex contains a minimal tail-anchor–targeting module and a mock BAG domain
J. Mock, J. Chartron, Ma’ayan Zaslaver, Yue Xu +2 more
2014Proceedings of the National Academy of Sciences of the United States of America88 citations Open access
Semantic Scholar
Model for eukaryotic tail-anchored protein binding based on the structure of Get3
C. Suloway, J. Chartron, Ma’ayan Zaslaver, W. Clemons
2009Proceedings of the National Academy of Sciences of the United States of America88 citations Open access
Semantic Scholar
Modeling the Effects of prl Mutations on the Escherichia coli SecY Complex
Margaret A. Smith, W. Clemons, C. DeMars, A. Flower
2005Journal of Bacteriology87 citations Open access
Semantic Scholar
Comprehensive proteomic profiling of outer membrane vesicles from Campylobacter jejuni
K. Jang, M. Sweredoski, Robert L. J. Graham, Sonja Hess +1 more
2013Journal of Proteomics85 citations Open access
Semantic Scholar
The glove-like structure of the conserved membrane protein TatC provides insight into signal sequence recognition in twin-arginine translocation
S. Ramasamy, R. Abrol, C. Suloway, W. Clemons
2013Structure77 citations Open access
Semantic Scholar
Structural characterization of the Get4/Get5 complex and its interaction with Get3
J. Chartron, C. Suloway, Ma’ayan Zaslaver, W. Clemons
2010Proceedings of the National Academy of Sciences of the United States of America77 citations Open access
Semantic Scholar
USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation
Yanfen Liu, N. Soetandyo, Jin-gu Lee, Liping Liu +3 more
2014eLife74 citations Open access
Semantic Scholar
The complex process of GETting tail-anchored membrane proteins to the ER
J. Chartron, W. Clemons, C. Suloway
2012Current Opinion in Structural Biology72 citations Open access
Semantic Scholar
Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal a novel interaction that forms a conserved dynamic interface
J. Chartron, D. VanderVelde, W. Clemons
2012Cell Reports70 citations Open access
Semantic Scholar
A Structural Model of the Sgt2 Protein and Its Interactions with Chaperones and the Get4/Get5 Complex*
J. Chartron, G. M. Gonzalez, W. Clemons
2011Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Structural insight into the protein translocation channel.
W. Clemons, J. Ménétret, C. Akey, T. Rapoport
2004Current Opinion in Structural Biology58 citations
Semantic Scholar
Crystal structure of ATP-bound Get3-Get4-Get5 complex reveals regulation of Get3 by Get4
H. Gristick, M. Rao, J. Chartron, M. Rome +2 more
2014Nature Structural &Molecular Biology55 citations Open access
Semantic Scholar
Precise timing of ATPase activation drives targeting of tail-anchored proteins
M. Rome, M. Rao, W. Clemons, S. Shan
2013Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
The mechanism of the phage encoded protein antibiotic from ΦX174
Anna K. Orta, Nadia Riera, Yan-Cheng E. Li, Shiho Tanaka +3 more
2023Science43 citations Open access
Semantic Scholar
Tail‐anchor targeting by a Get3 tetramer: the structure of an archaeal homologue
Christian J. M. Suloway, M. Rome, W. Clemons
2011EMBO Journal42 citations Open access
Semantic Scholar
Minimal requirements for inhibition of MraY by lysis protein E from bacteriophage ΦX174
Shiho Tanaka, W. Clemons
2012Molecular Microbiology40 citations Open access
Semantic Scholar
The STI1‐domain is a flexible alpha‐helical fold with a hydrophobic groove
Michelle Y Fry, Shyam M. Saladi, W. Clemons
2021Protein Science29 citations Open access
Semantic Scholar
Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex*
J. Chartron, D. VanderVelde, M. Rao, W. Clemons
2012Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Ultrastructure and complex polar architecture of the human pathogen Campylobacter jejuni
Axel Müller, M. Beeby, A. Mcdowall, J. Chow +2 more
2014MicrobiologyOpen27 citations Open access
Semantic Scholar
Structure of the twin-arginine signal-binding protein DmsD from Escherichia coli.
S. Ramasamy, W. Clemons
2009Acta Crystallographica. Section F : Structural Biology and Crystallization Communications23 citations Open access
Semantic Scholar
Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35
J. Mock, Yue Xu, Yi-Hong Ye, W. Clemons
2017Proceedings of the National Academy of Sciences of the United States of America21 citations Open access
Semantic Scholar
Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2
K. Lin, Michelle Y Fry, Shyam M. Saladi, W. Clemons
2021Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Novel FR-900493 Analogues That Inhibit the Outgrowth of Clostridium difficile Spores
Katsuhiko Mitachi, H. Yun, S. Kurosu, Shakiba Eslamimehr +4 more
2018ACS Omega20 citations Open access
Semantic Scholar
A Link Between Integral Membrane Protein Expression and Simulated Integration Efficiency
Stephen S. Marshall, Michiel J. M. Niesen, Axel Müller, K. Tiemann +5 more
2016Cell Reports20 citations Open access
Semantic Scholar
Mechanism of Assembly of a Substrate Transfer Complex during Tail-anchored Protein Targeting*
H. Gristick, M. Rome, J. Chartron, M. Rao +3 more
2015Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor
Katsuhiko Mitachi, D. Mingle, Wendy Effah, A. Sánchez-Ruiz +5 more
2022Angewandte Chemie17 citations Open access
Semantic Scholar
Sequence-based features that are determinant for tail-anchored membrane protein sorting in eukaryotes
Michelle Y Fry, Shyam M. Saladi, Alexandre Cunha, W. Clemons
2021Traffic : the International Journal of Intracellular Transport17 citations Open access
Semantic Scholar
A Semi-Synthesis of an Anticancer DPAGT1 Inhibitor from a Muraymycin Biosynthetic Intermediate
Katsuhiko Mitachi, Shou M. Kurosu, Shakiba Eslamimehr, Maddie R. Lemieux +3 more
2019Organic Letters16 citations Open access
Semantic Scholar
A statistical model for improved membrane protein expression using sequence-derived features
Shyam M. Saladi, Nauman Javed, Axel Müller, W. Clemons
2018Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Improving membrane protein expression by optimizing integration efficiency
Michiel J. M. Niesen, Stephen S. Marshall, T. Miller, W. Clemons
2017Journal of Biological Chemistry13 citations Open access
Semantic Scholar
Intradimeric Walker A ATPases: Conserved Features of A Functionally Diverse Family.
A. O. Maggiolo, S. Mahajan, D. Rees, W. Clemons
2023Journal of Molecular Biology12 citations Open access
Semantic Scholar
DPAGT1 Inhibitors of Capuramycin Analogues and Their Antimigratory Activities of Solid Tumors
Katsuhiko Mitachi, Rita Kansal, K. Hevener, Cody D. Gillman +6 more
2020Journal of Medicinal Chemistry11 citations Open access
Semantic Scholar
Complexity in targeting membrane proteins
Michelle Y Fry, W. Clemons
2018Science11 citations
Semantic Scholar
Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa
L. S. Marmont, Anna K. Orta, Becca W. A. Baileeves, D. Sychantha +7 more
2024Nature Microbiology10 citations Open access
Semantic Scholar
Chemoenzymatic syntheses of water-soluble lipid I fluorescent probes
Katsuhiko Mitachi, Shajila Siricilla, Lada Klaić, W. Clemons +1 more
2015Tetrahedron Letters10 citations Open access
Semantic Scholar
A practical synthesis of a novel DPAGT1 inhibitor, aminouridyl phenoxypiperidinbenzyl butanamide (APPB) for in vivo studies
Katsuhiko Mitachi, Shou M. Kurosu, Cody D. Gillman, H. Yun +2 more
2019MethodsX6 citations Open access
Semantic Scholar
Substrate Tolerance of Bacterial Glycosyltransferase MurG: Novel Fluorescence-based Assays
Katsuhiko Mitachi, H. Yun, Cody D. Gillman, Karolina Skorupińska-Tudek +3 more
2019ACS Infectious Diseases6 citations Open access
Semantic Scholar
A Cationic Cysteine-Hydrazide as an Enrichment Tool for the Mass Spectrometric Characterization of Bacterial Free Oligosaccharides
K. Jang, R. Nani, Anastasia Kalli, S. Levin +4 more
2015Analytical and Bioanalytical Chemistry5 citations Open access
Semantic Scholar
Convergent MurJ flippase inhibition by phage lysis proteins.
Yan-Cheng E. Li, S. Antillon, Grace F. Baron, Karthik Chamakura +2 more
2026Nature4 citations
Semantic Scholar
Nucleotide- and metalloid-driven conformational changes in the arsenite efflux ATPase ArsA
Shivansh Mahajan, Ashley E. Pall, Yan-Cheng E. Li, T. Stemmler +2 more
2025bioRxiv4 citations Open access
Semantic Scholar
Structures of Get3d reveal a distinct architecture associated with the emergence of photosynthesis
Alexandra N. Barlow, Mallahalli S. Manu, Shyam M. Saladi, Paul T. Tarr +6 more
2023Journal of Biological Chemistry4 citations Open access
Semantic Scholar
New Insights of Muraymycin A1 and Its Analogs as DPAGT1 Inhibitors
Katsuhiko Mitachi, Deidre Daria, J. Kirsh, Wendy Effah +3 more
2025Bioorganic chemistry (Print)3 citations Open access
Semantic Scholar
The client-binding domain of the cochaperone Sgt2 has a helical-hand structure that binds a short hydrophobic helix
K. Lin, Michelle Y Fry, Shyam M. Saladi, W. Clemons
2019bioRxiv3 citations Open access
Semantic Scholar
Decoding sequence-level information to predict membrane protein expression
Shyam M. Saladi, Nauman Javed, Axel Müller, W. Clemons
2017bioRxiv3 citations Open access
Semantic Scholar
Structural biologists, let’s mind our colors
Shyam M. Saladi, A. O. Maggiolo, Kate Radford, W. Clemons
2020bioRxiv2 citations Open access
Semantic Scholar
Structures of bacterial and human phosphoglycosyltransferases bound to a common inhibitor inform selective therapeutics
Beebee Yusrah Kaudeer, J. Kirsh, Katsuhiko Mitachi, J. Ochoa +5 more
2025bioRxiv1 citations Open access
Semantic Scholar
Being Black in biophysics.
Gail A. Robertson, W. Clemons, Theanne N. Griffith
2023Biophysical Journal1 citations Open access
Semantic Scholar

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