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G. Natsoulis · SciRah

Researcher profile · Semantic Scholar

G. Natsoulis

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G. Natsoulis — researcher profile on SciRah

h-index: 22
Works: 51
Citations: 2,607

Most-cited papers

Performance comparison of whole-genome sequencing platforms
Hugo Y. K. Lam, M. Clark, Rui Chen, Rong Chen +9 more
2011Nature Biotechnology324 citations Open access
Semantic Scholar
Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.
B. Ganter, S. Tugendreich, C. Pearson, E. Ayanoğlu +35 more
2005Journal of Biotechnology286 citations
Semantic Scholar
The HTS1 gene encodes both the cytoplasmic and mitochondrial histidine tRNA synthetases of S. cerevisiae.
G. Natsoulis, F. Hilger, G. Fink
1986Cell256 citations
Semantic Scholar
Convex optimization techniques for fitting sparse Gaussian graphical models
O. Banerjee, L. El Ghaoui, A. d'Aspremont, G. Natsoulis
2006International Conference on Machine Learning204 citations
Semantic Scholar
Hotspots for Unselected Tyl Transposition Events on Yeast Chromosome III Are near tRNA Genes and LTR Sequences
H. Ji, D. P. Moore, M. Blomberg, L. Braiterman +3 more
2003172 citations
Semantic Scholar
RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML.
Anna L. Brown, P. Arts, C. Carmichael, M. Babic +55 more
2020Blood Advances138 citations Open access
Semantic Scholar
Ultrasensitive detection of rare mutations using next-generation targeted resequencing
P. Flaherty, G. Natsoulis, Omkar Muralidharan, M. Winters +6 more
2011Nucleic Acids Research130 citations Open access
Semantic Scholar
Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer
L. Nadauld, Sarah Garcia, G. Natsoulis, J. Bell +13 more
2014Genome Biology129 citations Open access
Semantic Scholar
Classification of a large microarray data set: algorithm comparison and analysis of drug signatures.
G. Natsoulis, L. El Ghaoui, Gert R. G. Lanckriet, Alexander M. Tolley +6 more
2005Genome Research125 citations Open access
Semantic Scholar
A Gene Expression Signature that Predicts the Future Onset of Drug-Induced Renal Tubular Toxicity
M. Fielden, B. Eynon, G. Natsoulis, K. Jarnagin +2 more
2005Toxicologic pathology (Print)101 citations
Semantic Scholar
The liver pharmacological and xenobiotic gene response repertoire
G. Natsoulis, C. Pearson, J. Gollub, B. Eynon +8 more
2008Molecular Systems Biology84 citations Open access
Semantic Scholar
Robust Classification with Interval Data
L. El Ghaoui, Gert R. G. Lanckriet, G. Natsoulis
200376 citations
Semantic Scholar
New antiviral strategy using capsid-nuclease fusion proteins
G. Natsoulis, J. Boeke
1991Nature69 citations
Semantic Scholar
Ty1 transposition in Saccharomyces cerevisiae is nonrandom.
G. Natsoulis, W. Thomas, M. Roghmann, F. Winston +1 more
1989Genetics55 citations
Semantic Scholar
The products of the SPT10 and SPT21 genes of Saccharomyces cerevisiae increase the amplitude of transcriptional regulation at a large number of unlinked loci.
G. Natsoulis, C. Dollard, F. Winston, J. D. Boeke
1991The New biologist52 citations
Semantic Scholar
Efficient targeted resequencing of human germline and cancer genomes by oligonucleotide-selective sequencing
S. Myllykangas, Jason D. Buenrostro, G. Natsoulis, J. Bell +1 more
2011Nature Biotechnology50 citations Open access
Semantic Scholar
The SPT10 and SPT21 genes of Saccharomyces cerevisiae.
G. Natsoulis, F. Winston, J. D. Boeke
1994Genetics43 citations
Semantic Scholar
The RUNX1 database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy
Claire C. Homan, Sarah L. King-Smith, D. Lawrence, P. Arts +39 more
2021Haematologica40 citations Open access
Semantic Scholar
A Phase 2a Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Myelofibrosis
K. Pettit, A. Gerds, A. Yacoub, J. Watts +13 more
2019Blood38 citations Open access
Semantic Scholar
Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41
Claire C. Homan, M. Drazer, Kai Yu, D. Lawrence +61 more
2023Blood Advances36 citations Open access
Semantic Scholar
Doubling Ty1 element copy number in Saccharomyces cerevisiae: host genome stability and phenotypic effects.
J. D. Boeke, D. Eichinger, G. Natsoulis
1991Genetics33 citations
Semantic Scholar
A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Advanced Myelofibrosis
H. Gill, A. Yacoub, K. Pettit, T. Bradley +21 more
2021Blood22 citations Open access
Semantic Scholar
Identification of Novel LNK Mutations In Patients with Chronic Myeloproliferative Neoplasms and Related Disorders
Stephen T. Oh, Jacob M. Zahn, Carol D. Jones, Bing M. Zhang +12 more
201019 citations
Semantic Scholar
A Flexible Approach for Highly Multiplexed Candidate Gene Targeted Resequencing
G. Natsoulis, J. Bell, Hua Xu, Jason D. Buenrostro +7 more
2011PLoS ONE18 citations Open access
Semantic Scholar
A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Advanced Myelofibrosis (MF): Updated Results and Genomic Analyses
K. Pettit, H. Gill, A. Yacoub, T. Bradley +28 more
2022Blood14 citations Open access
Semantic Scholar
A cross-sample statistical model for SNP detection in short-read sequencing data
Omkar Muralidharan, G. Natsoulis, J. Bell, Daniel E. Newburger +4 more
2011Nucleic Acids Research12 citations Open access
Semantic Scholar
A programmable method for massively parallel targeted sequencing
E. Hopmans, G. Natsoulis, J. Bell, S. Grimes +2 more
2014Nucleic Acids Research11 citations Open access
Semantic Scholar
Detecting Mutations in Mixed Sample Sequencing Data Using Empirical Bayes
Omkar Muralidharan, G. Natsoulis, J. Bell, Hanlee P. Ji +1 more
201210 citations Open access
Semantic Scholar
P1051: A PHASE 2 STUDY OF IMG-7289 (BOMEDEMSTAT) IN PATIENTS WITH ADVANCED MYELOFIBROSIS
H. Gill, A. Yacoub, K. Pettit, T. Bradley +32 more
2022HemaSphere9 citations Open access
Semantic Scholar
Corrigendum: Performance comparison of whole-genome sequencing platforms
Hugo Y. K. Lam, M. Clark, Rui Chen, Rong Chen +9 more
2012Nature Biotechnology9 citations Open access
Semantic Scholar
Molecular Basis for Fungal Selectivity of Novel Antimitotic Compounds
T. Lila, T. Renau, L. Wilson, J. Philips +4 more
2003Antimicrobial Agents and Chemotherapy9 citations Open access
Semantic Scholar
Targeted sequencing library preparation by genomic DNA circularization
S. Myllykangas, G. Natsoulis, J. Bell, Hanlee P. Ji
2011BMC Biotechnology8 citations Open access
Semantic Scholar
Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1, GATA2 and DDX41
Anna L. Brown, Claire C. Homan, M. Drazer, Kai Yu +60 more
2022Blood6 citations
Semantic Scholar
Identification of Insertion Deletion Mutations from Deep Targeted Resequencing
G. Natsoulis, N. Zhang, K. Welch, J. Bell +1 more
2013Journal of Data Mining in Genomics & Proteomics6 citations Open access
Semantic Scholar
Chemogenomics – pharmacology with genomics tools
L. Browne, L. Furness, G. Natsoulis, C. Pearson +1 more
20025 citations
Semantic Scholar
Chemogenomics for Predictive Drug Assessment
L. Furness, C. Pearson, G. Natsoulis, Alan Engelberg +2 more
20034 citations
Semantic Scholar
The Human OligoGenome Resource: a database of oligonucleotide capture probes for resequencing target regions across the human genome
Daniel E. Newburger, G. Natsoulis, S. Grimes, J. Bell +3 more
2011Nucleic Acids Res.3 citations Open access
Semantic Scholar
SPT1O and SPT21 Are Required for Transcription of Particular Histone Genes in Saccharomyces cerevisiae
Catherine, Dollard, L. Stephanie, RICUPERO-HOVASSE +4 more
1 citations
Semantic Scholar
SPT 1 O and SPT 21 Are Required for Transcription of Particular Histone Genes in Saccharomyces cerevisiae
C. Dollard, Stephanie L. Ricupero-Hovasse, G. Natsoulis, J. Boeke +1 more
1 citations
Semantic Scholar
An Enhanced Sensitivity DNA Sequencing Protocol for the Detection in AML of Measurable Residual Disease (MRD) Applicable for All Mutations
H. Rienhoff, G. Natsoulis, Amber Jones, J. Peppe +3 more
2018Blood0 citations
Semantic Scholar
Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB
Anna L. Brown, M. Armstrong, D. Lawrence, Paul P. S. Wang +56 more
2018Blood0 citations
Semantic Scholar
Sheet 2 of 7 US 6 , 303 , 115 B 1 S . CERVISAE NULL MUTANTS COMPLEMENTED BY PATHOGEN ' S HOMOLOG
Stran Pools, G. Natsoulis, T. Mckelvey, ASSistant Examiner +1 more
20170 citations
Semantic Scholar
Abstract 3488: Surveying colorectal cancer genome for clinically actionable genomic amplifications with droplet digital PCR.
Rowza T. Rumma, Laura Miotke, L. Nadauld, G. Natsoulis +3 more
20130 citations
Semantic Scholar
Abstract 3165: Metastatic tumor evolution delineates clinically important oncogenic drivers in diffuse gastric cancer.
L. Nadauld, Sarah Garcia, G. Natsoulis, J. Bell +7 more
20130 citations
Semantic Scholar
Abstract 3232: Oligonucleotide-selective sequencing (OS-Seq): a rapid and efficient targeting technology for ultra-deep detection of cancer mutations and rearrangements.
E. Hopmans, G. Natsoulis, Jason D. Buenrostro, S. Grimes +2 more
20130 citations
Semantic Scholar
Abstract B6: Identification of novel mutations in the inhibitory adaptor protein LNK in patients with JAK2 V617F-negative and -positive chronic myeloproliferative neoplasms
Stephen T. Oh, Jacob M. Zahn, E. Simonds, J. Bell +12 more
20100 citations
Semantic Scholar
Classification of a large microarray data set : Algorithm comparison and analysis of drug signatures
G. Natsoulis, L. El Ghaoui, Gert R. G. Lanckriet, Alexander M. Tolley +6 more
20080 citations
Semantic Scholar
Inexpensive and automated predictive and mechanistic analysis of compound effects in vivo and in vitro using microarrays for discovery, lead optimization and preclinical safety assessment
J. Retief, G. Natsoulis, Alexander M. Tolley, B. Ganter +3 more
20060 citations
Semantic Scholar
308 Drugmatrix™ provides predictive chemogenomics solutions for safety assessment in drug discovery and development
P. Gee, Richard Mitchell, L. Browne, K. Kolaja +3 more
20030 citations
Semantic Scholar
The SPTlO and SPT 21 Genes of Saccharomyces cerevisiae
G. Natsoulis, F. Winston, J. Boeke
20020 citations
Semantic Scholar

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