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Y. Ebina · SciRah

Researcher profile · Semantic Scholar

Y. Ebina

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Y. Ebina — researcher profile on SciRah

h-index: 37
Works: 79
Citations: 5,995

Most-cited papers

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling.
Y. Ebina, L. Ellis, K. Jarnagin, M. Edery +8 more
1985Cell1,247 citations
Semantic Scholar
IRS1-independent defects define major nodes of insulin resistance.
Kyle L. Hoehn, C. Hohnen-Behrens, A. Cederberg, Lindsay E. Wu +4 more
2008Cell Metabolism312 citations Open access
Semantic Scholar
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity.
Y. Ebina, E. Araki, Masanori Taira, F. Shimada +6 more
1987Proceedings of the National Academy of Sciences of the United States of America299 citations Open access
Semantic Scholar
Intra-islet insulin suppresses glucagon release via GABA-GABAA receptor system.
E. Xu, Mohan Kumar, Y. Zhang, W. Ju +9 more
2006Cell Metabolism298 citations
Semantic Scholar
Insulin-stimulated GLUT4 translocation is relevant to the phosphorylation of IRS-1 and the activity of PI3-kinase.
F. Kanai, K. Ito, M. Todaka, H. Hayashi +6 more
1993Biochemical and Biophysical Research Communications - BBRC256 citations
Semantic Scholar
Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes
S. Ugi, T. Imamura, H. Maegawa, K. Egawa +6 more
2004Molecular and Cellular Biology245 citations Open access
Semantic Scholar
GLUT4 translocation by insulin in intact muscle cells: detection by a fast and quantitative assay
Qinghua Wang, Zayna A. Khayat, K. Kishi, Y. Ebina +1 more
1998FEBS Letters231 citations
Semantic Scholar
Use of RNA Interference-mediated Gene Silencing and Adenoviral Overexpression to Elucidate the Roles of AKT/Protein Kinase B Isoforms in Insulin Actions*
Takashi Katome, T. Obata, Rie Matsushima, Norihisa Masuyama +5 more
2003Journal of Biological Chemistry220 citations Open access
Semantic Scholar
Complete nucleotide sequence of the metapyrocatechase gene on the TOI plasmid of Pseudomonas putida mt-2.
C. Nakai, H. Kagamiyama, Mitsuhiro Nozaki, T. Nakazawa +3 more
1983Journal of Biological Chemistry220 citations Open access
Semantic Scholar
Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway.
K. Kishi, N. Muromoto, Yutaka Nakaya, I. Miyata +3 more
1998Diabetes188 citations
Semantic Scholar
Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor
M. Taira, N. Hashimoto, F. Shimada, Y. Suzuki +5 more
1989154 citations
Semantic Scholar
Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue
D. Lauro, Y. Kido, A. Castle, M. Zarnowski +3 more
1998Nature Genetics140 citations
Semantic Scholar
GLUT-4myc ectopic expression in L6 myoblasts generates a GLUT-4-specific pool conferring insulin sensitivity.
A. Ueyama, Karen Yaworsky, Qinghua Wang, Y. Ebina +1 more
1999American Journal of Physiology. Endocrinology and Metabolism119 citations
Semantic Scholar
Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells.
Y. Ebina, M. Edery, L. Ellis, D. Standring +3 more
1985Proceedings of the National Academy of Sciences of the United States of America113 citations Open access
Semantic Scholar
LexA protein is a repressor of the colicin E1 gene.
Y. Ebina, Y. Takahara, Fumio Kishi, Atsushi Nakazawa +1 more
1983Journal of Biological Chemistry107 citations Open access
Semantic Scholar
Nucleotide sequence of the structural gene for colicin E1 and predicted structure of the protein.
M. Yamada, Y. Ebina, T. Miyata, T. Nakazawa +1 more
1982Proceedings of the National Academy of Sciences of the United States of America103 citations Open access
Semantic Scholar
Nucleotide sequence surrounding transcription initiation site of xylABC operon on TOL plasmid of Pseudomonas putida.
S. Inouye, Y. Ebina, Atsushi Nakazawa, T. Nakazawa
1984Proceedings of the National Academy of Sciences of the United States of America99 citations Open access
Semantic Scholar
Increased insulin sensitivity and hypoinsulinemia in APS knockout mice.
A. Minami, M. Iseki, K. Kishi, Miao Wang +15 more
2003Diabetes91 citations Open access
Semantic Scholar
Rapid stimulation of glucose transport by mitochondrial uncoupling depends in part on cytosolic Ca2+ and cPKC.
Zayna A. Khayat, T. Tsakiridis, A. Ueyama, R. Somwar +2 more
1998American Journal of Physiology - Cell Physiology85 citations
Semantic Scholar
Insulin-resistant diabetes associated with partial deletion of insulin-receptor gene.
F. Shimada, M. Taira, Y. Suzuki, N. Hashimoto +5 more
1990The Lancet79 citations
Semantic Scholar
ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells.
Yuki Izawa, M. Yoshizumi, Y. Fujita, Nermin Ali +7 more
2005Experimental Cell Research75 citations
Semantic Scholar
Deficiency of Cbl-b Gene Enhances Infiltration and Activation of Macrophages in Adipose Tissue and Causes Peripheral Insulin Resistance in Mice
K. Hirasaka, S. Kohno, J. Goto, Harumi Furochi +11 more
2007Diabetes70 citations Open access
Semantic Scholar
Isolation of TOL and RP4 recombinants by integrative suppression
T. Nakazawa, E. Hayashi, T. Yokota, Y. Ebina +1 more
1978Journal of Bacteriology70 citations Open access
Semantic Scholar
Association of stomatin (band 7.2b) with Glut1 glucose transporter.
Jin-Zhong Zhang, H. Hayashi, Y. Ebina, Rainer Prohaska +1 more
1999Archives of Biochemistry and Biophysics69 citations
Semantic Scholar
Site-directed mutagenesis studies on the iron-binding domain and the determinant for the substrate oxygenation site of porcine leukocyte arachidonate 12-lipoxygenase.
Hiroshi Suzuki, K. Kishimoto, T. Yoshimoto, Shozo Yamamoto +4 more
1994Biochimica et Biophysica Acta67 citations
Semantic Scholar
Human diabetes associated with a deletion of the tyrosine kinase domain of the insulin receptor.
M. Taira, N. Hashimoto, F. Shimada, Y. Suzuki +6 more
1989Science66 citations
Semantic Scholar
AMP-Activated Protein Kinase Is Activated by the Stimulations of Gq-Coupled Receptors
K. Kishi, T. Yuasa, A. Minami, M. Yamada +5 more
200063 citations
Semantic Scholar
Cloning of a Drosophila cDNA encoding a polypeptide similar to the human insulin receptor precursor.
Y. Nishida, M. Hata, Yasuaki Nishizuka, W. Rutter +1 more
1986Biochemical and Biophysical Research Communications - BBRC62 citations
Semantic Scholar
Transcriptional Activation of the Glut1 Gene in Response to Oxidative Stress in L6 Myotubes*
N. Kozlovsky, A. Rudich, R. Potashnik, Y. Ebina +2 more
1997Journal of Biological Chemistry61 citations Open access
Semantic Scholar
Shikonin stimulates glucose uptake in 3T3-L1 adipocytes via an insulin-independent tyrosine kinase pathway.
Reiko Kamei, Y. Kitagawa, M. Kadokura, Fumiyuki Hattori +4 more
2002Biochemical and Biophysical Research Communications - BBRC58 citations
Semantic Scholar
Insulin Enhances Macrophage Scavenger Receptor-mediated Endocytic Uptake of Advanced Glycation End Products*
H. Sano, T. Higashi, Kenshi Matsumoto, J. Melkko +6 more
1998Journal of Biological Chemistry58 citations Open access
Semantic Scholar
Insulin treatment stimulates the tyrosine phosphorylation of the alpha-type 85-kDa subunit of phosphatidylinositol 3-kinase in vivo.
H. Hayashi, S. Kamohara, Yasuhiko Nishioka, F. Kanai +5 more
1992Journal of Biological Chemistry58 citations Open access
Semantic Scholar
Cyclic AMP-dependent initiation and rho-dependent termination of colicin E1 gene transcription.
Y. Ebina, Atsushi Nakazawa
1983Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Soluble Insulin Receptor Ectodomain Is Elevated in the Plasma of Patients With Diabetes
T. Obata, I. Yokota, Kazuhiro Yokoyama, Eiji Okamoto +14 more
2007Diabetes42 citations Open access
Semantic Scholar
Gq-coupled Receptors Transmit the Signal for GLUT4 Translocation via an Insulin-independent Pathway*
K. Kishi, H. Hayashi, Li-Hong Wang, S. Kamohara +5 more
1996Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Direct participation of lexA protein in repression of colicin E1 synthesis
Y. Ebina, F. Kishi, Atsushi Nakazawa
1982Journal of Bacteriology39 citations Open access
Semantic Scholar
AMP-Activated protein kinase is activated by the stimulations of G(q)-coupled receptors.
K. Kishi, T. Yuasa, A. Minami, M. Yamada +5 more
2000Biochemical and Biophysical Research Communications - BBRC37 citations
Semantic Scholar
Organization of the lexA gene of Escherichia coli and nucleotide sequence of the regulatory region.
T. Miki, Y. Ebina, Fumio Kishi, A. Nakazawa
1981Nucleic Acids Research36 citations Open access
Semantic Scholar
The nucleotide sequence surrounding the promoter region of colicin E1 gene.
Y. Ebina, Fumio Kishi, T. Miki, H. Kagamiyama +2 more
1981Gene36 citations
Semantic Scholar
Transient Effect of Platelet-derived Growth Factor on GLUT4 Translocation in 3T3-L1 Adipocytes*
Li-Hong Wang, H. Hayashi, Y. Ebina
1999Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Platelet-derived growth factor stimulates glucose transport in skeletal muscles of transgenic mice specifically expressing platelet-derived growth factor receptor in the muscle, but it does not affect blood glucose levels.
T. Yuasa, Rei Kakuhata, K. Kishi, T. Obata +6 more
2004Diabetes28 citations Open access
Semantic Scholar
Effect of growth hormone on the translocation of GLUT4 and its relation to insulin-like and anti-insulin action.
Ichiro Yokota, H. Hayashi, J. Matsuda, T. Saijo +4 more
1998Biochimica et Biophysica Acta24 citations Open access
Semantic Scholar
Gi-mediated translocation of GLUT4 is independent of p85/p110α and p110γ phosphoinositide 3-kinases but might involve the activation of Akt kinase
Li-Hong Wang, H. Hayashi, K. Kishi, Lu-Ping Z. Huang +4 more
200022 citations Open access
Semantic Scholar
Reconstitution of Insulin Signaling Pathways in Rat 3Y1 Cells Lacking Insulin Receptor and Insulin Receptor Substrate-1
T. Imanaka, H. Hayashi, K. Kishi, Li-Hong Wang +4 more
1998Journal of Biological Chemistry20 citations Open access
Semantic Scholar
APS-mediated ubiquitination of the insulin receptor enhances its internalization, but does not induce its degradation.
K. Kishi, K. Mawatari, Kikuko Sakai-Wakamatsu, T. Yuasa +5 more
2007Endocrine journal19 citations Open access
Semantic Scholar
Frequency of Mutations of Insulin Receptor Gene in Japanese Patients With NIDDM
M. Kan, F. Kanai, M. Iida, H. Jinnouchi +14 more
1995Diabetes18 citations
Semantic Scholar
Gene expression in vitro of colicin El plasmid.
Y. Ebina, Fumio Kishi, T. Nakazawa, A. Nakazawa
1979Nucleic Acids Research18 citations Open access
Semantic Scholar
Development of in vitro model of insulin receptor cleavage induced by high glucose in HepG2 cells.
T. Yuasa, K. Amo, S. Ishikura, Hisao Nagaya +3 more
2014Biochemical and Biophysical Research Communications - BBRC17 citations
Semantic Scholar
The Rab GTPase-activating protein AS160 as a common regulator of insulin- and Galphaq-mediated intracellular GLUT4 vesicle distribution.
T. Yuasa, K. Uchiyama, Y. Ogura, Masafumi Kimura +7 more
2009Endocrine journal17 citations Open access
Semantic Scholar
Effects of losartan in combination with or without exercise on insulin resistance in Otsuka Long-Evans Tokushima Fatty rats.
K. Ishizawa, M. Yoshizumi, K. Tsuchiya, Eiko Takishita +6 more
2001European Journal of Pharmacology17 citations
Semantic Scholar

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