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D. Standring · SciRah

Researcher profile · Semantic Scholar

D. Standring

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D. Standring — researcher profile on SciRah

h-index: 33
Works: 83
Citations: 4,232

Most-cited papers

Insulin-like growth factor II receptor as a multifunctional binding protein
David O. Morgan, J. C. Edman, D. Standring, V. Fried +3 more
1987Nature793 citations
Semantic Scholar
Identification of BMS-200475 as a potent and selective inhibitor of hepatitis B virus
S. Innaimo, M. Seifer, G. Bisacchi, D. Standring +2 more
1997Antimicrobial Agents and Chemotherapy257 citations Open access
Semantic Scholar
RNA- and DNA-binding activities in hepatitis B virus capsid protein: a model for their roles in viral replication
T. Hatton, Si-Yao Zhou, D. Standring
1992Journal of Virology220 citations Open access
Semantic Scholar
In Vitro Inhibition of Hepadnavirus Polymerases by the Triphosphates of BMS-200475 and Lobucavir
M. Seifer, R. Hamatake, R. Colonno, D. Standring
1998Antimicrobial Agents and Chemotherapy197 citations Open access
Semantic Scholar
Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.
C. Pierra, A. Amador, S. Benzaria, E. Cretton-scott +9 more
2006Journal of Medicinal Chemistry191 citations
Semantic Scholar
Reduction of aryl azides by thiols: implications for the use of photoaffinity reagents.
J. V. Staros, H. Bayley, D. Standring, J. Knowles
1978Biochemical and Biophysical Research Communications - BBRC172 citations
Semantic Scholar
A signal peptide encoded within the precore region of hepatitis B virus directs the secretion of a heterogeneous population of e antigens in Xenopus oocytes.
D. Standring, J. Ou, F. Masiarz, W. Rutter
1988Proceedings of the National Academy of Sciences of the United States of America156 citations Open access
Semantic Scholar
Synthesis and biological evaluation of aryl-phospho-indole as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
François-René Alexandre, A. Amador, S. Bot, Catherine Caillet +11 more
2011Journal of Medicinal Chemistry146 citations
Semantic Scholar
Hepatitis B virus capsid particles are assembled from core-protein dimer precursors.
Si-Yao Zhou, D. Standring
1992Proceedings of the National Academy of Sciences of the United States of America136 citations Open access
Semantic Scholar
Propane-1,3-dithiol: A selective reagent for the efficient reduction of alkyl and aryl azides to amines
H. Bayley, D. Standring, J. Knowles
1979130 citations
Semantic Scholar
Transcription of hepatitis B virus by RNA polymerase II
Leslie B. Rall, D. Standring, Orgad Laub, W. Rutter
1983Molecular and Cellular Biology118 citations Open access
Semantic Scholar
Efficacy of the Carbocyclic 2′-Deoxyguanosine Nucleoside BMS-200475 in the Woodchuck Model of Hepatitis B Virus Infection
E. Genovesi, L. Lamb, I. Medina, D. Taylor +5 more
1998Antimicrobial Agents and Chemotherapy116 citations Open access
Semantic Scholar
Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells.
Y. Ebina, M. Edery, L. Ellis, D. Standring +3 more
1985Proceedings of the National Academy of Sciences of the United States of America113 citations Open access
Semantic Scholar
Assembly of viral particles in Xenopus oocytes: pre-surface-antigens regulate secretion of the hepatitis B viral surface envelope particle.
D. Standring, Jing-Hsiung Ou, W. Rutter
1986Proceedings of the National Academy of Sciences of the United States of America95 citations Open access
Semantic Scholar
Synthesis of hepatitis B surface antigen in mammalian cells: expression of the entire gene and the coding region
O. Laub, L. Rall, M. A. Truett, Y. Shaul +3 more
1983Journal of Virology90 citations Open access
Semantic Scholar
Transcription of the hepatitis B surface antigen gene in cultured murine cells initiates within the presurface region
D. Standring, W. Rutter, H. Varmus, D. Ganem
1984Journal of Virology82 citations Open access
Semantic Scholar
A micromolar pool of antigenically distinct precursors is required to initiate cooperative assembly of hepatitis B virus capsids in Xenopus oocytes
M. Seifer, Si-Yao Zhou, D. Standring
1993Journal of Virology62 citations Open access
Semantic Scholar
Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.
C. Dousson, François-René Alexandre, A. Amador, Séverine Bonaric +23 more
2016Journal of Medicinal Chemistry59 citations Open access
Semantic Scholar
A protease-sensitive hinge linking the two domains of the hepatitis B virus core protein is exposed on the viral capsid surface
M. Seifer, D. Standring
1994Journal of Virology55 citations Open access
Semantic Scholar
Rat preprocarboxypeptidase A: cDNA sequence and preliminary characterization of the gene.
C. Quinto, M. Quiroga, W. Swain, William C. Nikovits +4 more
1982Proceedings of the National Academy of Sciences of the United States of America55 citations Open access
Semantic Scholar
Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir.
M. Seifer, A. Patty, I. Serra, Bin Li +1 more
2009Antiviral Research54 citations
Semantic Scholar
Assembly and antigenicity of hepatitis B virus core particles.
M. Seifer, D. Standring
1995Intervirology48 citations
Semantic Scholar
Antiviral beta-L-nucleosides specific for hepatitis B virus infection.
D. Standring, E. Bridges, L. Placidi, A. Faraj +15 more
2001Antiviral Chemistry & Chemotherapy46 citations
Semantic Scholar
Virus-Specific Cofactor Requirement and Chimeric Hepatitis C Virus/GB Virus B Nonstructural Protein 3
N. Butkiewicz, N. Yao, W. Zhong, J. Wright-Minogue +9 more
2000Journal of Virology46 citations Open access
Semantic Scholar
Recombinant human hepatitis B virus reverse transcriptase is active in the absence of the nucleocapsid or the viral replication origin, DR1
M. Seifer, D. Standring
1993Journal of Virology46 citations Open access
Semantic Scholar
Cys residues of the hepatitis B virus capsid protein are not essential for the assembly of viral core particles but can influence their stability
Si-Yao Zhou, D. Standring
1992Journal of Virology40 citations Open access
Semantic Scholar
Characterization of hepatitis B virus capsid particle assembly in Xenopus oocytes
Si-Yao Zhou, Shu-Qing Yang, D. Standring
1992Journal of Virology39 citations Open access
Semantic Scholar
2′-C-Methyl Branched Pyrimidine Ribonucleoside Analogues: Potent Inhibitors of RNA Virus Replication
S. Benzaria, D. Bardiot, Tony Bouisset, Clément Counor +20 more
2007Antiviral Chemistry & Chemotherapy38 citations
Semantic Scholar
Sequence and phenotypic analysis for resistance monitoring in hepatitis C virus drug development: recommendations from the HCV DRAG.
A. Kwong, I. Nájera, J. Bechtel, S. Bowden +25 more
2011Gastroenterology37 citations Open access
Semantic Scholar
Production of hepatitis B virus nucleocapsidlike core particles in Xenopus oocytes: assembly occurs mainly in the cytoplasm and does not require the nucleus
Si-Yao Zhou, D. Standring
1991Journal of Virology37 citations Open access
Semantic Scholar
Phenotypic mixing between different hepadnavirus nucleocapsid proteins reveals C protein dimerization to be cis preferential
Chuan-Hsiung Chang, S. Zhou, D. Ganem, D. Standring
1994Journal of Virology36 citations Open access
Semantic Scholar
588 IN VITRO ANTIVIRAL ACTIVITY AND PHARMACOLOGY OF IDX184, A NOVEL AND POTENT INHIBITOR OF HCV REPLICATION
E. Cretton-scott, C. Périgaud, S. Peyrottes, L. Licklider +14 more
200835 citations
Semantic Scholar
Generation of Replication-Competent Hepatitis B Virus Nucleocapsids in Insect Cells
M. Seifer, R. Hamatake, M. Bifano, D. Standring
1998Journal of Virology35 citations Open access
Semantic Scholar
Yeast tRNA3Leu gene transcribed and spliced in a HeLa cell extract.
D. Standring, Alejandro Venegas, W. Rutter
1981Proceedings of the National Academy of Sciences of the United States of America30 citations Open access
Semantic Scholar
In Vitro Activity and Resistance Profile of Samatasvir, a Novel NS5A Replication Inhibitor of Hepatitis C Virus
J. Bilello, L. Lallos, J. McCarville, M. L. La Colla +6 more
2014Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar
The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.
François-René Alexandre, Eric Badaroux, J. Bilello, S. Bot +29 more
2017Bioorganic & Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Phosphorus-31 nuclear magnetic resonance of dihydroxyacetone phosphate in the presence of triosephosphate isomerase. The question of nonproductive binding of the substrate hydrate.
Martin R. Webb, D. Standring, J. Knowles
1977Biochemistry27 citations
Semantic Scholar
Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320.
C. Parsy, François-René Alexandre, Valérie Bidau, Florence Bonnaterre +21 more
2015Bioorganic & Medicinal Chemistry Letters23 citations
Semantic Scholar
514 HBV resistance determination from the telbivudine globe registration trial
D. Standring, M. Seifer, A. Patty, C. Chapron +4 more
200623 citations
Semantic Scholar
Hepatitis B virus p25 precore protein accumulates in Xenopus oocytes as an untranslocated phosphoprotein with an uncleaved signal peptide
Shu-Qing Yang, M. Walter, D. Standring
1992Journal of Virology22 citations Open access
Semantic Scholar
NM 283 has potent antiviral activity against genotype 1 chronic hepatitis C virus (HCV-1) infection in the chimpanzee
D. Standring, R. Lanford, T. Wright, R. Chung +14 more
200321 citations
Semantic Scholar
Hepatitis B virus encodes an RNA polymerase III transcript
D. Standring, Leslie B. Rall, Orgad Laub, W. Rutter
1983Molecular and Cellular Biology20 citations Open access
Semantic Scholar
Synthesis and studies of 3'-C-trifluoromethyl nucleoside analogues bearing adenine or cytosine as the base.
Frédéric Jeannot, G. Gosselin, D. Standring, Martin Bryant +4 more
2002Bioorganic & Medicinal Chemistry18 citations
Semantic Scholar
Photoaffinity labeling of lactate dehydrogenase by the carbene derived from the 3-diazirino analogue of nicotinamide adenine dinucleotide.
D. Standring, J. Knowles
1980Biochemistry18 citations
Semantic Scholar
67 POTENT ANTIVIRAL ACTIVITY OF SECOND GENERATION NUCLEOSIDE INHIBITORS, IDX102 AND IDX184, IN HCV-INFECTED CHIMPANZEES
D. Standring, R. Lanford, E. Cretton-scott, L. Licklider +8 more
200816 citations Open access
Semantic Scholar
Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.
Claire Pierra Rouvière, A. Amador, Eric Badaroux, Thierry Convard +19 more
2016Bioorganic & Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Design, synthesis and antiviral evaluation of 2'-C-methyl branched guanosine pronucleotides: the discovery of IDX184, a potent liver-targeted HCV polymerase inhibitor.
Gwenaëlle Sizun, C. Pierra, Jérôme Peyronnet, Eric Badaroux +10 more
2015Future Medicinal Chemistry12 citations
Semantic Scholar
Evaluation of the role of three candidate human kinases in the conversion of the hepatitis C virus inhibitor 2'-C-methyl-cytidine to its 5'-monophosphate metabolite.
N. Golitsina, F. Danehy, R. Fellows, E. Cretton-scott +1 more
2010Antiviral Research12 citations
Semantic Scholar
91 ANTIVIRAL ACTIVITY OF THE LIVER-TARGETED NUCLEOTIDE HCV POLYMERASE INHIBITOR IDX184 CORRELATES WITH TROUGH SERUM LEVELS OF THE NUCLEOSIDE METABOLITE IN HCV-INFECTED CHIMPANZEES
D. Standring, R. Lanford, B. Li, R. J. Panzo +4 more
200912 citations
Semantic Scholar
Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease.
C. Parsy, François-René Alexandre, G. Brandt, Catherine Caillet +17 more
2014Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar

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