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T. Mckay · SciRah

Researcher profile · Semantic Scholar

T. Mckay

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T. Mckay — researcher profile on SciRah

h-index: 25
Works: 78
Citations: 1,578

Most-cited papers

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming
Kate Hawkins, S. Joy, J. Delhove, Vassilios Kotiadis +8 more
2016Cell Reports153 citations Open access
Semantic Scholar
Notch Signaling Through Jagged‐1 Is Necessary to Initiate Chondrogenesis in Human Bone Marrow Stromal Cells but Must Be Switched off to Complete Chondrogenesis
Rachel A. Oldershaw, S. Tew, Amanda M. Russell, K. Meade +4 more
2008Stem Cells86 citations
Semantic Scholar
MicroRNA miR-107 is overexpressed in pituitary adenomas and inhibits the expression of aryl hydrocarbon receptor-interacting protein in vitro.
G. Trivellin, H. Butz, J. Delhove, S. Igreja +6 more
2012American Journal of Physiology. Endocrinology and Metabolism81 citations
Semantic Scholar
Antiproliferative and Antimigratory Effects of a Novel YAP–TEAD Interaction Inhibitor Identified Using in Silico Molecular Docking
Sarah A. Smith, R. Sessions, D. Shoemark, Christopher Williams +7 more
2019Journal of Medicinal Chemistry80 citations Open access
Semantic Scholar
Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway.
I. McNeish, S. Bell, T. Mckay, T. Tenev +2 more
2003Experimental Cell Research76 citations
Semantic Scholar
Shed syndecan-2 inhibits angiogenesis
G. De Rossi, Alun R. Evans, Emma Kay, A. Woodfin +3 more
2014Journal of Cell Science70 citations Open access
Semantic Scholar
The role of hypoxia in stem cell potency and differentiation.
Kate Hawkins, Tyson V. Sharp, T. Mckay
2013Regenerative medicine70 citations
Semantic Scholar
Survivin interacts with Smac/DIABLO in ovarian carcinoma cells but is redundant in Smac-mediated apoptosis.
I. McNeish, R. Lopes, S. Bell, T. Mckay +4 more
2005Experimental Cell Research63 citations Open access
Semantic Scholar
Cell signalling pathways underlying induced pluripotent stem cell reprogramming.
Kate Hawkins, S. Joy, T. Mckay
2014World Journal of Stem Cells59 citations Open access
Semantic Scholar
Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression
S. Buckley, S. Howe, V. Sheard, N. Ward +4 more
2008Gene Therapy59 citations
Semantic Scholar
BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity.
M. Munye, A. Shoemark, R. Hirst, J. Delhove +6 more
2017American Journal of Physiology - Lung cellular and Molecular Physiology49 citations Open access
Semantic Scholar
In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters
S. Buckley, J. Delhove, D. Perocheau, R. Karda +9 more
2015Scientific Reports48 citations Open access
Semantic Scholar
FGF signalling through Fgfr2 isoform IIIb regulates adrenal cortex development
L. Guasti, W. C. Candy Sze, T. Mckay, R. Grose +1 more
2013Molecular and Cellular Endocrinology46 citations Open access
Semantic Scholar
Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes
S. Tew, M. Peffers, T. Mckay, Emma T. Lowe +3 more
2009American Journal of Physiology - Cell Physiology46 citations Open access
Semantic Scholar
Procaspase 3 expression in ovarian carcinoma cells increases survivin transcription which can be countered with a dominant-negative mutant, survivin T34A; a combination gene therapy strategy
T. Mckay, S. Bell, T. Tenev, V. Stoll +3 more
2003Oncogene44 citations Open access
Semantic Scholar
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype
C. Soldati, I. Lopez-Fabuel, L. G. Wanderlingh, M. García-Macía +19 more
2021EMBO Molecular Medicine41 citations Open access
Semantic Scholar
Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy
C. Vink, J. Counsell, D. Perocheau, R. Karda +7 more
2017Molecular Therapy39 citations Open access
Semantic Scholar
Cigarette smoke extract profoundly suppresses TNFα-mediated proinflammatory gene expression through upregulation of ATF3 in human coronary artery endothelial cells
J. Teasdale, Georgina G. J. Hazell, A. M. Peachey, G. Sala-Newby +5 more
2017Scientific Reports38 citations Open access
Semantic Scholar
Luciferin Detection After Intranasal Vector Delivery Is Improved by Intranasal Rather Than Intraperitoneal Luciferin Administration
S. Buckley, S. Howe, A. Rahim, H. Buning +8 more
2008Human Gene Therapy37 citations
Semantic Scholar
Gene delivery of a mutant TGFβ3 reduces markers of scar tissue formation after cutaneous wounding.
S. Waddington, Rachel A Crossley, V. Sheard, S. Howe +5 more
2010Molecular Therapy34 citations Open access
Semantic Scholar
A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia
D. Foxler, Katherine S. Bridge, J. G. Foster, Paul Grevitt +23 more
2018EMBO Molecular Medicine32 citations Open access
Semantic Scholar
Functional Expression of Secreted Proteins from a Bicistronic Retroviral Cassette Based on Foot-and-Mouth Disease Virus 2A Can Be Position Dependent
D. Rothwell, Rachel A Crossley, J. Bridgeman, V. Sheard +5 more
2010Human Gene Therapy28 citations
Semantic Scholar
NF-κB Activity Initiates Human ESC-Derived Neural Progenitor Cell Differentiation by Inducing a Metabolic Maturation Program
Lorna M. Fitzpatrick, Kate Hawkins, J. Delhove, E. Fernandez +7 more
2018Stem Cell Reports27 citations Open access
Semantic Scholar
Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters
Duncan C. Miller, S. Harmer, Ariel H. B. Poliandri, M. Nobles +7 more
2017Stem Cell Research27 citations Open access
Semantic Scholar
Perinatal Gene Transfer to the Liver
T. Mckay, A. Rahim, S. Buckley, N. Ward +3 more
2011Current pharmaceutical design25 citations Open access
Semantic Scholar
Cellular models of Batten disease
Christopher Minnis, Christopher D. Thornton, Lorna M. Fitzpatrick, T. Mckay
2020Biochimica et Biophysica Acta - Molecular Basis of Disease20 citations Open access
Semantic Scholar
An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny
A. Roig-Merino, M. Urban, Matthias Bozza, Julia D. Peterson +8 more
2021Stem Cell Reports19 citations Open access
Semantic Scholar
Human feeder cell line for derivation and culture of hESc/hiPSc.
T. Mckay, M. Camarasa, Banu Iskender, Jin-Pei Ye +9 more
2011Stem Cell Research19 citations Open access
Semantic Scholar
Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells.
Ariel H. B. Poliandri, Duncan C. Miller, S. Howard, M. Nobles +6 more
2017Molecular and Cellular Endocrinology17 citations Open access
Semantic Scholar
Derivation of Man-1 and Man-2 research grade human embryonic stem cell lines
M. Camarasa, Robbie Kerr, Sharon F. Sneddon, Nicola Bates +7 more
2010In vitro Cellular & Developmental Biology-Animal16 citations Open access
Semantic Scholar
Secretin-mediated gene delivery, a specific targeting mechanism with potential for treatment of biliary and pancreatic disease in cystic fibrosis.
T. Mckay, Paul R. Reynolds, S. Jezzard, D. Curiel +1 more
2002Molecular Therapy16 citations Open access
Semantic Scholar
An In Vitro Whole-Organ Liver Engineering for Testing of Genetic Therapies
M. Lorvellec, A. Pellegata, Alice Maestri, Chiara Turchetta +15 more
2020iScience14 citations Open access
Semantic Scholar
Continual conscious bioluminescent imaging in freely moving somatotransgenic mice
R. Karda, D. Perocheau, N. Suff, J. Ng +8 more
2017Scientific Reports14 citations Open access
Semantic Scholar
Evidence for Contribution of CD4+CD25+ Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery
M. Nivsarkar, S. Buckley, A. Parker, D. Perocheau +4 more
2015Journal of Immunological Research13 citations Open access
Semantic Scholar
Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors
Christopher D. Thornton, S. Fielding, Kinga Karbowniczek, A. Roig-Merino +8 more
2021Molecular Therapy: Methods & Clinical Development10 citations Open access
Semantic Scholar
Epithelial cadherin regulates transition between the naïve and primed pluripotent states in mouse embryonic stem cells
Aseel M. Sharaireh, Lorna M. Fitzpatrick, Chris M Ward, T. Mckay +1 more
2020Stem Cells10 citations Open access
Semantic Scholar
Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice
J. Delhove, S. Buckley, D. Perocheau, R. Karda +4 more
2017Scientific Reports10 citations Open access
Semantic Scholar
A functional human motor unit platform engineered from human embryonic stem cells and immortalized skeletal myoblasts
Marwah Abd Al Samid, J. McPhee, J. Saini, T. Mckay +6 more
2018Stem Cells and Cloning : Advances and Applications9 citations Open access
Semantic Scholar
Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors
R. Karda, A. Rahim, Andrew M. S. Wong, N. Suff +14 more
2016Scientific Reports8 citations Open access
Semantic Scholar
Bioluminescence Monitoring of Promoter Activity In Vitro and In Vivo.
J. Delhove, R. Karda, Kate Hawkins, Lorna M. Fitzpatrick +2 more
2017Methods in molecular biology5 citations Open access
Semantic Scholar
Genome Editing in Stem Cells
Lorna M. Fitzpatrick, T. Mckay
2015Current Stem Cell Reports4 citations Open access
Semantic Scholar
MicroRNA miR-107 is overexpressed in pituitary adenomas and in vitro inhibits 1 the expression of aryl hydrocarbon receptor-interacting protein (AIP)
G. Trivellin, H. Butz, J. Delhove, S. Igreja +7 more
20124 citations
Semantic Scholar
Continual Conscious Bioluminescent Imaging in Freely Moving Mice.
Juan Antinao Diaz, A. Geard, Lorna M. Fitzpatrick, J. Delhove +4 more
2019Methods in molecular biology3 citations
Semantic Scholar
81. Modification of HEK 293 cell integrin expression profile allows convenient large-scale roller bottle production of lentiviral vectors
Manij Patel, D. Wilcox, Angela M. Giddings, T. Mckay +1 more
20043 citations Open access
Semantic Scholar
Non-invasive somatotransgenic bioimaging in living animals
J. Delhove, R. Karda, Lorna M. Fitzpatrick, S. Buckley +2 more
20202 citations Open access
Semantic Scholar
CLN7 mutation causes aberrant redistribution of protein isoforms and contributes to Batten disease pathobiology
Aseel M. Sharaireh, Marta Guevara-Ferrer, Saúl Herranz-Martín, M. García-Macía +16 more
2022bioRxiv1 citations Open access
Semantic Scholar
Non-invasive somatotransgenic bioimaging in living animals [version 1; peer review: 2 approved with reservations]
J. Delhove, R. Karda, Lorna M. Fitzpatrick, S. Buckley +2 more
20211 citations
Semantic Scholar
Generation of Light-Producing, Somatic-Transgenic Mice Using Lentivirus and Adeno-Associated Virus Vectors
R. Karda, D. Perocheau, S. Buckley, J. Delhove +7 more
20161 citations
Semantic Scholar
Novel LTR-1 Lentiviral Vectors Are Fully Functional Following the Removal of HIV-1 Gag-RRE Sequences
J. Counsell, C. Vink, D. Perocheau, R. Karda +8 more
20151 citations Open access
Semantic Scholar
134. Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Hypoxic Ischaemic Encephalopathy
R. Karda, J. Delhove, S. Buckley, A. Rahim +7 more
20151 citations Open access
Semantic Scholar

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