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D. Perocheau · SciRah

Researcher profile · Semantic Scholar

D. Perocheau

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D. Perocheau — researcher profile on SciRah

h-index: 20
Works: 57
Citations: 3,268

Most-cited papers

The exosome journey: from biogenesis to uptake and intracellular signalling
Sonam Gurung, D. Perocheau, Loukia Touramanidou, J. Baruteau
2021Cell communication and signaling : CCS1,605 citations Open access
Semantic Scholar
IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production
K. Blazek, Hayley L Eames, M. Weiss, A. Byrne +6 more
2015Journal of Experimental Medicine208 citations Open access
Semantic Scholar
IRF5 controls both acute and chronic inflammation
M. Weiss, A. Byrne, K. Blazek, David G. Saliba +4 more
2015Proceedings of the National Academy of Sciences of the United States of America146 citations Open access
Semantic Scholar
Fetal gene therapy for neurodegenerative disease of infants
Giulia Massaro, C. Mattar, Andrew M. S. Wong, E. Sirka +18 more
2018Nature Medicine145 citations Open access
Semantic Scholar
Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis
F. McCann, A. Palfreeman, Melanie R. Andrews, D. Perocheau +5 more
2010Arthritis Research & Therapy138 citations Open access
Semantic Scholar
IRF5 Is a Specific Marker of Inflammatory Macrophages In Vivo
M. Weiss, K. Blazek, A. Byrne, D. Perocheau +1 more
2013Mediators of Inflammation129 citations Open access
Semantic Scholar
Clinical applications for exosomes: Are we there yet?
D. Perocheau, Loukia Touramanidou, Sonam Gurung, P. Gissen +1 more
2021British Journal of Pharmacology111 citations Open access
Semantic Scholar
Selective Tumor Necrosis Factor Receptor I Blockade Is Antiinflammatory and Reveals Immunoregulatory Role of Tumor Necrosis Factor Receptor II in Collagen‐Induced Arthritis
F. McCann, D. Perocheau, Gerhard Ruspi, K. Blazek +5 more
2014Arthritis & Rheumatology111 citations
Semantic Scholar
TNF receptor 2 signaling prevents DNA methylation at the Foxp3 promoter and prevents pathogenic conversion of regulatory T cells
W. Tseng, Yi-Shu Huang, F. Clanchy, K. Mcnamee +6 more
2019Proceedings of the National Academy of Sciences of the United States of America78 citations Open access
Semantic Scholar
Age-Related Seroprevalence of Antibodies Against AAV-LK03 in a UK Population Cohort
D. Perocheau, S. Cunningham, Juhee Lee, Juan Antinao Diaz +8 more
2019Human Gene Therapy72 citations Open access
Semantic Scholar
Ascending Vaginal Infection Using Bioluminescent Bacteria Evokes Intrauterine Inflammation, Preterm Birth, and Neonatal Brain Injury in Pregnant Mice
N. Suff, R. Karda, Juan Antinao Diaz, J. Ng +7 more
2018American Journal of Pathology48 citations Open access
Semantic Scholar
In vivo bioimaging with tissue-specific transcription factor activated luciferase reporters
S. Buckley, J. Delhove, D. Perocheau, R. Karda +9 more
2015Scientific Reports48 citations Open access
Semantic Scholar
Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism
J. Ng, S. Barral, Carmen De La Fuente Barrigon, G. Lignani +27 more
2021Science Translational Medicine45 citations Open access
Semantic Scholar
Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer
J. Baruteau, D. Perocheau, J. Hanley, M. Lorvellec +18 more
2018Nature Communications45 citations Open access
Semantic Scholar
Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy
C. Vink, J. Counsell, D. Perocheau, R. Karda +7 more
2017Molecular Therapy39 citations Open access
Semantic Scholar
Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload
N. Plotegher, D. Perocheau, R. Ferrazza, Giulia Massaro +7 more
2019Cell Death and Differentiation37 citations Open access
Semantic Scholar
Safety and efficacy of an engineered hepatotropic AAV gene therapy for ornithine transcarbamylase deficiency in cynomolgus monkeys
J. Baruteau, S. Cunningham, B. Yilmaz, D. Perocheau +7 more
2021Molecular Therapy: Methods & Clinical Development33 citations Open access
Semantic Scholar
Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis
Yi-Shu Huang, W. Tseng, F. Clanchy, L. Topping +13 more
2021Proceedings of the National Academy of Sciences of the United States of America30 citations Open access
Semantic Scholar
Beclin‐1‐mediated activation of autophagy improves proximal and distal urea cycle disorders
Leandro R. Soria, Sonam Gurung, G. de Sabbata, D. Perocheau +15 more
2020bioRxiv30 citations Open access
Semantic Scholar
Cervical Gene Delivery of the Antimicrobial Peptide, Human β-Defensin (HBD)-3, in a Mouse Model of Ascending Infection-Related Preterm Birth
N. Suff, R. Karda, Juan Antinao Diaz, J. Ng +8 more
2019bioRxiv24 citations Open access
Semantic Scholar
Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors
Adrian Westhaus, Marti Cabanes-Creus, Kimberley Dilworth, Erhua Zhu +23 more
2022bioRxiv20 citations Open access
Semantic Scholar
Gene Therapy for Inherited Metabolic Diseases
B. Yilmaz, Sonam Gurung, D. Perocheau, J. Counsell +1 more
2020Journal of mother and child20 citations
Semantic Scholar
Targeting the respiratory muscles of fetal sheep for prenatal gene therapy for Duchenne muscular dystrophy.
B. Weisz, A. David, L. Gregory, D. Perocheau +7 more
2005American Journal of Obstetrics and Gynecology19 citations
Semantic Scholar
An In Vitro Whole-Organ Liver Engineering for Testing of Genetic Therapies
M. Lorvellec, A. Pellegata, Alice Maestri, Chiara Turchetta +15 more
2020iScience14 citations Open access
Semantic Scholar
Continual conscious bioluminescent imaging in freely moving somatotransgenic mice
R. Karda, D. Perocheau, N. Suff, J. Ng +8 more
2017Scientific Reports14 citations Open access
Semantic Scholar
The exosome journey: from biogenesis to uptake and intracellular signalling
Sonam Gurung, D. Perocheau, Loukia Touramanidou, J. Baruteau
2021Cell Communication and Signaling13 citations Open access
Semantic Scholar
Evidence for Contribution of CD4+CD25+ Regulatory T Cells in Maintaining Immune Tolerance to Human Factor IX following Perinatal Adenovirus Vector Delivery
M. Nivsarkar, S. Buckley, A. Parker, D. Perocheau +4 more
2015Journal of Immunological Research13 citations Open access
Semantic Scholar
mRNA therapy restores ureagenesis and corrects glutathione metabolism in argininosuccinic aciduria
Sonam Gurung, O. V. Timmermand, D. Perocheau, A. L. Gil-Martinez +21 more
2022bioRxiv10 citations Open access
Semantic Scholar
Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice
J. Delhove, S. Buckley, D. Perocheau, R. Karda +4 more
2017Scientific Reports10 citations Open access
Semantic Scholar
Generation of light-producing somatic-transgenic mice using adeno-associated virus vectors
R. Karda, A. Rahim, Andrew M. S. Wong, N. Suff +14 more
2016Scientific Reports8 citations Open access
Semantic Scholar
Re-structuring lentiviral vectors to express genomic RNA via cap-dependent translation
J. Counsell, Guillaume De Brabandere, R. Karda, Marc Moore +6 more
2020Molecular Therapy: Methods & Clinical Development6 citations Open access
Semantic Scholar
Ex vivo primary liver sections recapitulate disease phenotype and therapeutic rescue for liver monogenic diseases
D. Perocheau, Sonam Gurung, Loukia Touramanidou, C. Duff +9 more
2023bioRxiv3 citations Open access
Semantic Scholar
Correction: Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload
N. Plotegher, D. Perocheau, R. Ferrazza, Giulia Massaro +7 more
2019Cell Death and Differentiation2 citations Open access
Semantic Scholar
Argininosuccinic aciduria fosters neuronal nitrosative stress reversed by Asl gene transfer
J. Baruteau, D. Perocheau, J. Hanley, Eridan Rocha-Ferreira +16 more
2018bioRxiv1 citations Open access
Semantic Scholar
Novel LTR-1 Lentiviral Vectors Are Fully Functional Following the Removal of HIV-1 Gag-RRE Sequences
J. Counsell, C. Vink, D. Perocheau, R. Karda +8 more
20151 citations Open access
Semantic Scholar
134. Generation of Light-Emitting Somatic-Transgenic Mice for Disease Modelling of Hypoxic Ischaemic Encephalopathy
R. Karda, J. Delhove, S. Buckley, A. Rahim +7 more
20151 citations Open access
Semantic Scholar
Macrophage inhibitor clodronate enhances liver transduction of lentiviral but not AAV vectors or mRNA lipid nanoparticles in vivo
Loukia Touramanidou, Sonam Gurung, Claudiu A. Cozmescu, D. Perocheau +12 more
2023bioRxiv0 citations Open access
Semantic Scholar
Correction: Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload
N. Plotegher, D. Perocheau, R. Ferrazza, Giulia Massaro +7 more
2020Cell Death and Differentiation0 citations Open access
Semantic Scholar
Beclin-1-mediated activation of autophagy improves proximal and distal urea cycle disorders.
L. Soria, D. Perocheau, Giulia De Sabbata, A. Angelis +10 more
20200 citations
Semantic Scholar
Gene Therapy for Infantile Parkinsonism
J. Ng, S. Barral, Barrigon Cdlf., G. Lignani +25 more
20190 citations
Semantic Scholar
British Society for Gene and Cell Therapy Annual Conference Friday 27th April 2018 Regent's Conference Centre, London, UK www.bsgct.org
Natasha Myhill, M. Spindler, David Johnson, J. Bridgeman +71 more
2018Human Gene Therapy0 citations Open access
Semantic Scholar
Assessment of the Immunogenicity Against AAV with the LK03 Chimeric Capsid Variant in the Human Population
D. Perocheau, J. Baruteau, S. Waddington, S. Cunningham +3 more
20170 citations
Semantic Scholar
SAT0005 DNA methylation inhibitors produce sustained remission of arthritis in mice and promote regulatory T cell responses
W. Tseng, I.-S. Huang, F. Clanchy, K. Mcnamee +7 more
20170 citations
Semantic Scholar
GBA1 deficiency sensitises neurons to glutamate toxicity and causes calcium dyshomeostasis
Nicoletta Plotegher, D. Perocheau, Giulia Massaro, A. Rahim +2 more
20170 citations
Semantic Scholar
Rescue and Phenotypic Correction in Argininosuccinate Lyase-Deficient Mice by AAV8.ASL Transfer
J. Baruteau, D. Perocheau, J. Hanley, Eridan Rocha-Ferreira +13 more
20170 citations
Semantic Scholar
437. A Light-Producing Model of Infection-Related Preterm Birth
N. Suff, R. Karda, D. Perocheau, J. Delhove +5 more
20160 citations Open access
Semantic Scholar
AAV8-mediated gene therapy rescue of lethal Argininosuccinate lyase-deficient mice.
J. Baruteau, J. Hanley, S. Buckley, P. Gissen +9 more
20160 citations
Semantic Scholar
305. Generation of Light-Producing, Somatic-Transgenic Mice Using Lentivirus and Adeno-Associated Virus Vectors
R. Karda, D. Perocheau, S. Buckley, J. Delhove +7 more
20160 citations Open access
Semantic Scholar
Intravenously administered gene therapy for the treatment of neuronopathic Gaucher Disease
Giulia Massaro, D. Perocheau, S. Cuka, M. Hughes +5 more
20160 citations
Semantic Scholar
Evaluating Promoter Regulated Dopaminergic Neuron Targeting with AAV9 Delivered To the Neonatal Mouse
J. Ng, R. Karda, Giulia Massaro, E. Meyer +8 more
20150 citations Open access
Semantic Scholar

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