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Yan Zhao · SciRah

Researcher profile · Semantic Scholar

Yan Zhao

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Yan Zhao — researcher profile on SciRah

h-index: 40
Works: 177
Citations: 5,707

Most-cited papers

METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance
Qiang Wang, Chen Chen, Q. Ding, Yan Zhao +10 more
2019Gut724 citations
Semantic Scholar
Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: a clinical and in vitro investigation.
Yan Zhao, Qin-Hao Guo, Jie-Jing Chen, Jun Hu +2 more
2014Oncology Report277 citations Open access
Semantic Scholar
Preclinical evaluation of a novel ATM inhibitor, KU59403, in vitro and in vivo in p53 functional and dysfunctional models of human cancer
M. Batey, Yan Zhao, S. Kyle, C. Richardson +5 more
2013Molecular Cancer Therapeutics151 citations Open access
Semantic Scholar
Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
M. Lamphier, W. Zheng, E. Latz, M. Spyvee +16 more
2014Molecular Pharmacology141 citations
Semantic Scholar
BRAF-activated long non-coding RNA contributes to colorectal cancer migration by inducing epithelial-mesenchymal transition
Qin-Hao Guo, Yan Zhao, Jie-Jing Chen, Jun Hu +3 more
2014Oncology Letters118 citations Open access
Semantic Scholar
BRAF-activated long non-coding RNA contributes to cell proliferation and activates autophagy in papillary thyroid carcinoma
Yong Wang, Qin-Hao Guo, Yan Zhao, Jie-Jing Chen +3 more
2014Oncology Letters117 citations Open access
Semantic Scholar
Multiple Functions and Mechanisms Underlying the Role of METTL3 in Human Cancers
Wen-Hui Zheng, Xiaoshen Dong, Yan Zhao, Shuo Wang +4 more
2019Frontiers in Oncology88 citations Open access
Semantic Scholar
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
M. Ladds, I. V. van Leeuwen, C. Drummond, S. Chu +42 more
2018Nature Communications86 citations Open access
Semantic Scholar
Circular RNA circTNPO3 Regulates Paclitaxel Resistance of Ovarian Cancer Cells by miR-1299/NEK2 Signaling Pathway
Bing Xia, Zi-Tong Zhao, Yin Wu, Ying Wang +2 more
2020Molecular Therapy: Nucleic Acids67 citations Open access
Semantic Scholar
Exosomal miRNA-205 promotes breast cancer chemoresistance and tumorigenesis through E2F1
Yan Zhao, Li Jin, Xiao-Yu Zhang
2021Aging66 citations Open access
Semantic Scholar
Long noncoding RNA LINC00152 promotes cell proliferation through competitively binding endogenous miR‐125b with MCL‐1 by regulating mitochondrial apoptosis pathways in ovarian cancer
Pu-Xiang Chen, Xiao-Ling Fang, Bing Xia, Yan Zhao +2 more
2018Cancer Medicine66 citations Open access
Semantic Scholar
Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy
Catherine E. Willoughby, Yan-Yan Jiang, H. Thomas, E. Willmore +19 more
2019Journal of Clinical Investigation56 citations Open access
Semantic Scholar
SDF-1/CXCR4 signaling up-regulates survivin to regulate human sacral chondrosarcoma cell cycle and epithelial–mesenchymal transition via ERK and PI3K/AKT pathway
Peng Yang, G. Wang, Hongjun Huo, Qiang Li +2 more
2014Medical Oncology53 citations
Semantic Scholar
Mortalin is a prognostic factor of gastric cancer with normal p53 function
K. Ando, E. Oki, Yan Zhao, Ayae Ikawa-Yoshida +7 more
2014Gastric Cancer52 citations Open access
Semantic Scholar
Prognostic relevance of KRAS and BRAF mutations in Japanese patients with colorectal cancer
R. Nakanishi, Jun Harada, M. Tuul, Yan Zhao +7 more
2013International Journal of Clinical Oncology48 citations
Semantic Scholar
Simultaneous targeting of glycolysis and oxidative phosphorylation as a therapeutic strategy to treat diffuse large B-cell lymphoma
R. A. Noble, H. Thomas, Yan Zhao, Lili Herendi +6 more
2022British Journal of Cancer47 citations Open access
Semantic Scholar
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.
G. Chessari, I. Hardcastle, J. Ahn, B. Anil +39 more
2021Journal of Medicinal Chemistry45 citations Open access
Semantic Scholar
Isoalantolactone Inhibits UM-SCC-10A Cell Growth via Cell Cycle Arrest and Apoptosis Induction
Min-Ju Wu, Hua Zhang, Jiehua Hu, Zhi-Yong Weng +6 more
2013PLoS ONE45 citations Open access
Semantic Scholar
In vitro neutralization of autocrine IL‑10 affects Op18/stathmin signaling in non‑small cell lung cancer cells.
Yan Zhao, Sangyan Chen, Fang-Yun Shen, D. Long +3 more
2018Oncology Report44 citations Open access
Semantic Scholar
MicroRNA-125a-5p enhances the sensitivity of esophageal squamous cell carcinoma cells to cisplatin by suppressing the activation of the STAT3 signaling pathway
Yan Zhao, Ke Ma, Shu-Jun Yang, Xiaosan Zhang +4 more
2018International Journal of Oncology43 citations Open access
Semantic Scholar
Upregulation of Limk1 caused by microRNA-138 loss aggravates the metastasis of ovarian cancer by activation of Limk1/cofilin signaling.
Pu-Xiang Chen, Meng-Jun Zeng, Yan Zhao, Xiao-Ling Fang
2014Oncology Report43 citations Open access
Semantic Scholar
Mechanism and biological significance of the overexpression of IFITM3 in gastric cancer.
Jun Hu, Shu-Wei Wang, Yan Zhao, Qin-Hao Guo +5 more
2014Oncology Report42 citations Open access
Semantic Scholar
Introduction of exogenous wild‑type p53 mediates the regulation of oncoprotein 18/stathmin signaling via nuclear factor‑κB in non‑small cell lung cancer NCI‑H1299 cells.
Sangyan Chen, Yan Zhao, Fang-Yun Shen, D. Long +2 more
2019Oncology Report40 citations Open access
Semantic Scholar
Structurally diverse MDM2–p53 antagonists act as modulators of MDR-1 function in neuroblastoma
Lin-Di Chen, Yan Zhao, G. Halliday, P. Berry +8 more
2014British Journal of Cancer40 citations Open access
Semantic Scholar
Hsa-miR-217 Inhibits the Proliferation, Migration, and Invasion in Non-small Cell Lung Cancer Cells Via Targeting SIRT1 and P53/KAI1 Signaling
Wenxia Jiang, Li-Li Hou, Juan Wei, Yi-Feng Du +3 more
2020Balkan Medical Journal37 citations Open access
Semantic Scholar
Targeted Knockdown of IQGAP1 Inhibits the Progression of Esophageal Squamous Cell Carcinoma In Vitro and In Vivo
Xiao-Xia Wang, Kang Wang, Xiao-Zhong Li, Liqin Zhai +7 more
2014PLoS ONE35 citations Open access
Semantic Scholar
Therapeutic effect of co-culture of rat bone marrow mesenchymal stem cells and degenerated nucleus pulposus cells on intervertebral disc degeneration.
M. Shi, Yan Zhao, Yue Sun, Da-Qi Xin +2 more
2021The spine journal34 citations
Semantic Scholar
CD13 Induces Autophagy to Promote Hepatocellular Carcinoma Cell Chemoresistance Through the P38/Hsp27/CREB/ATG7 Pathway
Yan Zhao, Hui Wu, X. Xing, Yuqian Ma +9 more
2020Journal of Pharmacology and Experimental Therapeutics34 citations Open access
Semantic Scholar
LncRNA NONHSAT141924 promotes paclitaxel chemotherapy resistance through p-CREB/Bcl-2 apoptosis signaling pathway in breast cancer
M. Gu, Wen-Hui Zheng, Ming-Di Zhang, Xiaoshen Dong +4 more
2020Journal of Cancer33 citations Open access
Semantic Scholar
Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma
Lin-Di Chen, F. Pastorino, P. Berry, Jennifer J. Bonner +10 more
2019International Journal of Cancer31 citations Open access
Semantic Scholar
LncRNA ZEB1‐AS1 down‐regulation suppresses the proliferation and invasion by inhibiting ZEB1 expression in oesophageal squamous cell carcinoma
Yan Zhao, Ning Wang, Xiaosan Zhang, Hong-Tao Liu +1 more
2019Journal of Cellular and Molecular Medicine30 citations Open access
Semantic Scholar
Expression and clinical significance of SALL4 and β-catenin in colorectal cancer
Li-Liang Hao, Yan Zhao, Zhen Wang, Hongzhuan Yin +7 more
2016Journal of Molecular Histology30 citations
Semantic Scholar
Equol Induces Mitochondria-Dependent Apoptosis in Human Gastric Cancer Cells via the Sustained Activation of ERK1/2 Pathway
Zhi-Ping Yang, Yan Zhao, Yahong Yao, Jun Li +2 more
2016Molecules and Cells30 citations Open access
Semantic Scholar
Notoginsenoside R1 protects oxygen and glucose deprivation‐induced injury by upregulation of miR‐21 in cardiomyocytes
Zeng-Jia Liu, Hai-yang Wang, Guoliang Hou, H. Cao +2 more
2018Journal of Cellular Biochemistry29 citations
Semantic Scholar
AZD1480, a JAK inhibitor, inhibits cell growth and survival of colorectal cancer via modulating the JAK2/STAT3 signaling pathway.
Shu-Wei Wang, Jun Hu, Qingming Guo, Yan Zhao +5 more
2014Oncology Report29 citations Open access
Semantic Scholar
BACH1 promotes the progression of esophageal squamous cell carcinoma by inducing the epithelial–mesenchymal transition and angiogenesis
Yan Zhao, Jia-Jia Gao, Xiufeng Xie, Peng Nan +3 more
2021Cancer Medicine28 citations Open access
Semantic Scholar
High salt induces P-glycoprotein mediated treatment resistance in breast cancer cells through store operated calcium influx
Duaa Babaer, Suneetha Amara, Michael T. Ivy, Yan Zhao +3 more
2018OncoTarget28 citations Open access
Semantic Scholar
BC-02 eradicates liver cancer stem cells by upregulating the ROS-dependent DNA damage.
Chunhui Dou, Chun-Yan Fang, Yan Zhao, Xiaoyan Fu +10 more
2017International Journal of Oncology25 citations Open access
Semantic Scholar
Autophagy contributes to falcarindiol-induced cell death in breast cancer cells with enhanced endoplasmic reticulum stress
T. Lu, M. Gu, Yan Zhao, Xin-Yu Zheng +1 more
2017PLoS ONE25 citations Open access
Semantic Scholar
Diaryl- and triaryl-pyrrole derivatives: inhibitors of the MDM2–p53 and MDMX–p53 protein–protein interactions
T. Blackburn, S. Ahmed, C. Coxon, Junfeng Liu +11 more
2013MedChemComm25 citations Open access
Semantic Scholar
Nigericin inhibits epithelial ovarian cancer metastasis by suppressing the cell cycle and epithelial−mesenchymal transition
Wen Wang, Yan Zhao, Shu-Juan Yao, Xiu-Juan Cui +5 more
2017Biochemistry (Moscow)22 citations
Semantic Scholar
CircVAPA exerts oncogenic property in non‐small cell lung cancer by the miR‐876‐5p/WNT5A axis
Yan Zhao, Qiang-Sheng Dai, Xiao-Hong Fu, Qian-Qi Chen +3 more
2021Journal of Gene Medicine21 citations
Semantic Scholar
lncRNA PART1, manipulated by transcriptional factor FOXP2, suppresses proliferation and invasion in ESCC by regulating the miR-18a-5p/SOX6 signaling axis
Yan Zhao, Qing Zhang, Hong-Tao Liu, Ning Wang +2 more
2021Oncology Report20 citations Open access
Semantic Scholar
Cholesterol Analogs with Degradation-resistant Alkyl Side Chains Are Effective Mycobacterium tuberculosis Growth Inhibitors*
D. J. Frank, Yan Zhao, S. Wong, D. Basudhar +2 more
2016Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Equol inhibits proliferation of human gastric carcinoma cells via modulating Akt pathway.
Zhi-Ping Yang, Yan Zhao, Fang Huang, Jie Chen +3 more
2015World Journal of Gastroenterology20 citations Open access
Semantic Scholar
MicroRNA-21 promotes cell metastasis in cervical cancer through modulating epithelial-mesenchymal transition
Ya-Ling Tang, Yan Zhao, Jing Ran, Yi-Feng Wang
2020Oncology Letters19 citations Open access
Semantic Scholar
TCF7L2 and EGR1 synergistic activation of transcription of LCN2 via an ERK1/2-dependent pathway in esophageal squamous cell carcinoma cells.
Yan Zhao, Qiaoxi Xia, Yan Liu, Wenjing Bai +11 more
2019Cellular Signalling19 citations
Semantic Scholar
Downregulation of RAI14 inhibits the proliferation and invasion of breast cancer cells
M. Gu, Wen-Hui Zheng, Ming-Di Zhang, Xiaoshen Dong +5 more
2019Journal of Cancer18 citations Open access
Semantic Scholar
Catalytic Activities of Tumor-Specific Human Cytochrome P450 CYP2W1 Toward Endogenous Substrates
Yan Zhao, Debin Wan, Jun Yang, B. Hammock +1 more
2016Drug Metabolism And Disposition18 citations Open access
Semantic Scholar
Aberrations of BUBR1 and TP53 gene mutually associated with chromosomal instability in human colorectal cancer.
Yan Zhao, K. Ando, E. Oki, Ayae Ikawa-Yoshida +6 more
2014Anticancer Research18 citations
Semantic Scholar

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