Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

D. Zechel · SciRah

Researcher profile · Semantic Scholar

D. Zechel

Share profile

D. Zechel — researcher profile on SciRah

h-index: 35
Works: 92
Citations: 4,180

Most-cited papers

Glycosidase mechanisms: anatomy of a finely tuned catalyst.
D. Zechel, S. Withers
1999Accounts of Chemical Research719 citations
Semantic Scholar
Phosphonate Biochemistry.
G. P. Horsman, D. Zechel
2017Chemical Reviews395 citations
Semantic Scholar
Utilization of Glyphosate as Phosphate Source: Biochemistry and Genetics of Bacterial Carbon-Phosphorus Lyase
B. Hove-Jensen, D. Zechel, B. Jochimsen
2014Microbiology and Molecular Reviews196 citations Open access
Semantic Scholar
Mapping the conformational itinerary of beta-glycosidases by X-ray crystallography.
G. Davies, V. Ducros, A. Varrot, D. Zechel
2003Biochemical Society Transactions157 citations
Semantic Scholar
Iminosugar glycosidase inhibitors: structural and thermodynamic dissection of the binding of isofagomine and 1-deoxynojirimycin to beta-glucosidases.
D. Zechel, A. Boraston, T. Gloster, Catherine M. Boraston +4 more
2003Journal of the American Chemical Society154 citations
Semantic Scholar
Dissection of nucleophilic and acid-base catalysis in glycosidases.
D. Zechel, S. Withers
2001Current Opinion in Chemical Biology128 citations
Semantic Scholar
An automated Genomes-to-Natural Products platform (GNP) for the discovery of modular natural products
Chad W. Johnston, M. Skinnider, M. Wyatt, Xiang Li +5 more
2015Nature Communications127 citations Open access
Semantic Scholar
Chloramphenicol biosynthesis: the structure of CmlS, a flavin-dependent halogenase showing a covalent flavin-aspartate bond.
K. Podzelinska, R. Latimer, Anupam Bhattacharya, L. Vining +2 more
2010Journal of Molecular Biology121 citations
Semantic Scholar
Glycosidase inhibition: an assessment of the binding of 18 putative transition-state mimics.
T. Gloster, P. Meloncelli, R. Stick, D. Zechel +2 more
2007Journal of the American Chemical Society121 citations
Semantic Scholar
Substrate distortion by a beta-mannanase: snapshots of the Michaelis and covalent-intermediate complexes suggest a B(2,5) conformation for the transition state.
V. Ducros, D. Zechel, G. Murshudov, H. Gilbert +4 more
2002Angewandte Chemie112 citations
Semantic Scholar
The E358S mutant of Agrobacterium sp. β‐glucosidase is a greatly improved glycosynthase
Christoph M. Mayer, D. Zechel, S. Reid, R. Warren +1 more
2000FEBS Letters103 citations
Semantic Scholar
Understanding how diverse beta-mannanases recognize heterogeneous substrates.
L. Tailford, V. Ducros, J. Flint, S. Roberts +8 more
2009Biochemistry102 citations Open access
Semantic Scholar
Pre-steady state kinetic analysis of an enzymatic reaction monitored by time-resolved electrospray ionization mass spectrometry.
D. Zechel, L. Konermann, Stephen G. Withers, D. J. Douglas
1998Biochemistry100 citations
Semantic Scholar
Five phosphonate operon gene products as components of a multi-subunit complex of the carbon-phosphorus lyase pathway
B. Jochimsen, S. Lolle, Fern R. McSorley, M. Nabi +3 more
2011Proceedings of the National Academy of Sciences of the United States of America84 citations Open access
Semantic Scholar
β-Mannosynthase: Synthesis of β-Mannosides with a Mutant β-Mannosidase.
O. Nashiru, D. Zechel, D. Stoll, Taraneh Mohammadzadeh +2 more
2001Angewandte Chemie81 citations
Semantic Scholar
Direct observation of the protonation state of an imino sugar glycosidase inhibitor upon binding.
A. Varrot, C. A. Tarling, J. Macdonald, R. Stick +3 more
2003Journal of the American Chemical Society73 citations
Semantic Scholar
PhnY and PhnZ comprise a new oxidative pathway for enzymatic cleavage of a carbon-phosphorus bond.
Fern R. McSorley, P. B. Wyatt, A. Martı́nez, E. Delong +2 more
2012Journal of the American Chemical Society71 citations
Semantic Scholar
Understanding How Diverse -Mannanases Recognise Heterogeneous Substrates.
L. Tailford, V. Ducros, J. Flint, S. Roberts +8 more
200967 citations
Semantic Scholar
A cryptic polyene biosynthetic gene cluster in Streptomyces calvus is expressed upon complementation with a functional bldA gene.
Lindsay Kalan, Arne Gessner, M. Thaker, N. Waglechner +5 more
2013Chemistry and Biology61 citations Open access
Semantic Scholar
Rational design of an aryl-C-glycoside catalyst from a natural product O-glycosyltransferase.
Johannes Härle, S. Günther, Benjamin Lauinger, Monika Weber +4 more
2011Chemistry and Biology61 citations Open access
Semantic Scholar
Anatomy of glycosynthesis: structure and kinetics of the Humicola insolens Cel7B E197A and E197S glycosynthase mutants.
V. Ducros, C. A. Tarling, D. Zechel, A. Brzozowski +5 more
2004Chemistry and Biology61 citations Open access
Semantic Scholar
Physiological role of phnP-specified phosphoribosyl cyclic phosphodiesterase in catabolism of organophosphonic acids by the carbon-phosphorus lyase pathway.
B. Hove-Jensen, Fern R. McSorley, D. Zechel
2011Journal of the American Chemical Society57 citations
Semantic Scholar
Thermal and Transition-Metal-Catalyzed Ring-Opening Polymerization (ROP) of [1]Silaferrocenophanes with Chlorine Substituents at Silicon: A Route to Tunable Poly(ferrocenylsilanes)
D. Zechel, K. Hultzsch, R. Rulkens, David Balaishis +5 more
199655 citations
Semantic Scholar
Mechanism, mutagenesis, and chemical rescue of a beta-mannosidase from cellulomonas fimi.
D. Zechel, S. Reid, D. Stoll, O. Nashiru +2 more
2003Biochemistry54 citations
Semantic Scholar
Enzymatic synthesis of carbon-fluorine bonds.
D. Zechel, S. Reid, O. Nashiru, Christoph D. Mayer +4 more
2001Journal of the American Chemical Society51 citations
Semantic Scholar
Structure and Kinetic Investigation of Streptococcus pyogenes Family GH38 α-Mannosidase
M. Suits, Yan-Ping Zhu, E. Taylor, J. Walton +3 more
2010PLoS ONE50 citations Open access
Semantic Scholar
Biological Control of Potato Common Scab With Rare Isatropolone C Compound Produced by Plant Growth Promoting Streptomyces A1RT
Arslan Sarwar, Z. Latif, Songya Zhang, Jing Zhu +2 more
2018Frontiers in Microbiology47 citations Open access
Semantic Scholar
Antitumor compounds from Streptomyces sp. KML-2, isolated from Khewra salt mines, Pakistan
Usman Aftab, D. Zechel, I. Sajid
2015Biological Research44 citations Open access
Semantic Scholar
Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates
L. V. van Staalduinen, Fern R. McSorley, K. Schiessl, Jacqueline Séguin +4 more
2014Proceedings of the National Academy of Sciences of the United States of America42 citations Open access
Semantic Scholar
Catabolism and Detoxification of 1-Aminoalkylphosphonic Acids: N-Acetylation by the phnO Gene Product
B. Hove-Jensen, Fern R. McSorley, D. Zechel
2012PLoS ONE40 citations Open access
Semantic Scholar
Crystal Structure of PhnH: an Essential Component of Carbon-Phosphorus Lyase in Escherichia coli
M. Adams, Yan Luo, B. Hove-Jensen, Shu-Mei He +3 more
2007Journal of Bacteriology40 citations Open access
Semantic Scholar
Secondary nucleotide messenger c-di-GMP exerts a global control on natural product biosynthesis in streptomycetes
Roman Makitrynskyy, O. Tsypik, D. Nuzzo, T. Paululat +2 more
2020Nucleic Acids Research38 citations Open access
Semantic Scholar
Biosynthesis of the Fluorinated Natural Product Nucleocidin in Streptomyces calvus Is Dependent on the bldA‐Specified Leu‐tRNAUUA Molecule
Xi-Ming Zhu, Stefanie Hackl, M. Thaker, Lindsay Kalan +11 more
2015ChemBioChem38 citations
Semantic Scholar
Synthesis, structural characterization, electrochemical properties and polymerization behaviour of the first silicon-bridged [1.1]ferrocenophane [{Fe(η-C5H4)2SiMe2}2]
D. Zechel, D. Foucher, J. Pudelski, G. Yap +2 more
199537 citations
Semantic Scholar
Characterization of covalently bonded proteins on poly(methyl methacrylate) by X-ray photoelectron spectroscopy.
G. W. Nelson, Megan Perry, Shu-Mei He, D. Zechel +1 more
2010Colloids and Surfaces B: Biointerfaces36 citations
Semantic Scholar
Structure of PhnP, a Phosphodiesterase of the Carbon-Phosphorus Lyase Pathway for Phosphonate Degradation*
K. Podzelinska, Shu-Mei He, Matthew Wathier, A. Yakunin +4 more
2009Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Novel WS9326A derivatives and one novel Annimycin derivative with antimalarial activity are produced by Streptomyces asterosporus DSM 41452 and its mutant
Songya Zhang, Jing Zhu, D. Zechel, C. Jessen-Trefzer +3 more
2017ChemBioChem30 citations Open access
Semantic Scholar
Accumulation of Intermediates of the Carbon-Phosphorus Lyase Pathway for Phosphonate Degradation in phn Mutants of Escherichia coli
B. Hove-Jensen, Tina J Rosenkrantz, D. Zechel, M. Willemoës
2009Journal of Bacteriology29 citations Open access
Semantic Scholar
Rebeccamycin and Staurosporine Biosynthesis: Insight into the Mechanisms of the Flavin‐Dependent Monooxygenases RebC and StaC
K. Groom, Anupam Bhattacharya, D. Zechel
2011ChemBioChem27 citations
Semantic Scholar
-Mannosynthase: Synthesis of -Mannosides with a Mutant -Mannosidase
O. Nashiru, D. Zechel, D. Stoll, Taraneh Mohammadzadeh +2 more
200126 citations
Semantic Scholar
Structure and mechanism of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway.
Shu-Mei He, Matthew Wathier, K. Podzelinska, M. Wong +5 more
2011Biochemistry24 citations
Semantic Scholar
Oxidative carbon backbone rearrangement in rishirilide biosynthesis.
O. Tsypik, Roman Makitrynskyy, Britta Frensch, D. Zechel +3 more
2020Journal of the American Chemical Society23 citations Open access
Semantic Scholar
Identification of Glu-120 as the catalytic nucleophile in Streptomyces lividans endoglucanase celB.
D. Zechel, Shou-Ming He, Claude Dupont, S. G. Withers
1998Biochemical Journal22 citations Open access
Semantic Scholar
Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis.
W. Offen, D. Zechel, S. Withers, H. Gilbert +1 more
2009Chemical Communications19 citations
Semantic Scholar
5.12 – Glycosyl Transferase Mechanisms
D. Zechel, S. Withers
199919 citations
Semantic Scholar
An Oxidative Pathway for Microbial Utilization of Methylphosphonic Acid as a Phosphate Source.
Simanga R. Gama, M. Vogt, Thomas Kalina, Kendall Hupp +3 more
2019ACS Chemical Biology18 citations
Semantic Scholar
Genome mining reveals the origin of a bald phenotype and a cryptic nucleocidin gene cluster in Streptomyces asterosporus DSM 41452.
Songya Zhang, Dennis Klementz, Jing Zhu, Roman Makitrynskyy +4 more
2019Journal of Biotechnology17 citations
Semantic Scholar
Changing Biosynthetic Profiles by Expressing bldA in Streptomyces Strains
Arne Gessner, Tanja Heitzler, Songya Zhang, Christine Klaus +5 more
2015ChemBioChem16 citations
Semantic Scholar
Biosynthesis of the Fungal Organophosphonate Fosfonochlorin Involves an Iron(II) and 2‐(Oxo)glutarate Dependent Oxacyclase
Simanga R. Gama, T. Stanković, Kendall Hupp, Ahmed Al Hejami +6 more
2021ChemBioChem14 citations Open access
Semantic Scholar
Rational design of hybrid natural products by utilizing the promiscuity of an amide synthetase.
Jing Zhu, Songya Zhang, D. Zechel, T. Paululat +1 more
2019ACS Chemical Biology13 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

S. Withers×12
Invite
S. Withers — researcher profile on SciRah
G. Davies×10
Invite
G. Davies — researcher profile on SciRah
A. Bechthold×10
Invite
A. Bechthold — researcher profile on SciRah
B. Hove-Jensen×9
Invite
B. Hove-Jensen — researcher profile on SciRah

Fern R. McSorley

×6

Invite

Fern R. McSorley — researcher profile on SciRah

Invite

V. Ducros — researcher profile on SciRah

Invite

Z. Jia — researcher profile on SciRah

Invite

H. Gilbert — researcher profile on SciRah

Invite

D. Stoll — researcher profile on SciRah

Songya Zhang×5

Invite

Songya Zhang — researcher profile on SciRah

Invite

O. Nashiru — researcher profile on SciRah

Invite

Jing Zhu — researcher profile on SciRah