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A. Boraston · SciRah

Researcher profile · Semantic Scholar

A. Boraston

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A. Boraston — researcher profile on SciRah

h-index: 56
Works: 403
Citations: 12K

Most-cited papers

Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes.
W. Abbott, O. Alber, E. Bayer, J. Berrin +97 more
2018Glycobiology192 citations Open access
Semantic Scholar
Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont
B. Pluvinage, J. Grondin, Carolyn Amundsen, L. Klassen +10 more
2018Nature Communications101 citations Open access
Semantic Scholar
(p)ppGpp and the Stringent Response: An Emerging Threat to Antibiotic Therapy.
J. Hobbs, A. Boraston
2019ACS Infectious Diseases93 citations
Semantic Scholar
Insights into the κ/ι-carrageenan metabolism pathway of some marine Pseudoalteromonas species
A. Hettle, J. Hobbs, B. Pluvinage, C. Vickers +11 more
2019Communications Biology66 citations Open access
Semantic Scholar
Endo-fucoidan hydrolases from glycoside hydrolase family 107 (GH107) display structural and mechanistic similarities to α-l-fucosidases from GH29
C. Vickers, Feng Liu, K. Abe, O. Salama-Alber +5 more
2018Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Glycan‐metabolizing enzymes in microbe–host interactions: the Streptococcus pneumoniae paradigm
J. Hobbs, B. Pluvinage, A. Boraston
2018FEBS Letters55 citations
Semantic Scholar
Metabolism of a hybrid algal galactan by members of the human gut microbiome
C. Robb, J. Hobbs, B. Pluvinage, G. Reintjes +13 more
2022Nature Chemical Biology49 citations
Semantic Scholar
The Molecular Basis of Polysaccharide Sulfatase Activity and a Nomenclature for Catalytic Subsites in this Class of Enzyme.
A. Hettle, C. Vickers, C. Robb, Feng Liu +3 more
2018Structure46 citations Open access
Semantic Scholar
The Glycoprotease CpaA Secreted by Medically Relevant Acinetobacter Species Targets Multiple O-Linked Host Glycoproteins
M. F. Haurat, Nichollas E. Scott, Gisela Di Venanzio, Juvenal Lopez +4 more
2020mBio43 citations Open access
Semantic Scholar
Sulfatases: Critical Enzymes for Algal Polysaccharide Processing
A. Hettle, C. Vickers, A. Boraston
2022Frontiers in Plant Science37 citations Open access
Semantic Scholar
The gastrointestinal pathogen Campylobacter jejuni metabolizes sugars with potential help from commensal Bacteroides vulgatus
Jolene M. Garber, H. Nothaft, B. Pluvinage, M. Stahl +12 more
2020Communications Biology35 citations Open access
Semantic Scholar
The glycoconjugate-degrading enzymes of Clostridium perfringens: tailored catalysts for breaching the intestinal mucus barrier.
Kristin E. Low, Steven P. Smith, D. W. Abbott, A. Boraston
2020Glycobiology33 citations
Semantic Scholar
Architecturally complex O-glycopeptidases are customized for mucin recognition and hydrolysis
B. Pluvinage, E. Ficko-Blean, I. Noach, C. Stuart +5 more
2021Proceedings of the National Academy of Sciences of the United States of America32 citations Open access
Semantic Scholar
Structural analysis of broiler chicken small intestinal mucin O-glycan modification by Clostridium perfringens.
Jaclyn L. MacMillan, Sara D. Vicaretti, Benjamin Noyovitz, Xiaohui Xing +9 more
2019Poultry Science29 citations Open access
Semantic Scholar
Clinical Mutations That Partially Activate the Stringent Response Confer Multidrug Tolerance in Staphylococcus aureus
D. Bryson, A. Hettle, A. Boraston, J. Hobbs
2019Antimicrobial Agents and Chemotherapy28 citations Open access
Semantic Scholar
A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond
Brendon J. Medley, Leif Leclaire, Nicole K. Thompson, Keira E. Mahoney +6 more
2022Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Biochemical Reconstruction of a Metabolic Pathway from a Marine Bacterium Reveals Its Mechanism of Pectin Depolymerization
J. Hobbs, A. Hettle, C. Vickers, A. Boraston
2018Applied and Environmental Microbiology26 citations Open access
Semantic Scholar
Properties of a family 56 carbohydrate-binding module and its role in the recognition and hydrolysis of β-1,3-glucan
A. Hettle, Alexander Fillo, K. Abe, P. Massel +4 more
2017Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Structural and functional analysis of four family 84 glycoside hydrolases from the opportunistic pathogen Clostridium perfringens.
B. Pluvinage, P. Massel, Kristyn Burak, A. Boraston
2019Glycobiology22 citations Open access
Semantic Scholar
Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens
J. Hobbs, B. Pluvinage, M. Robb, Steven P. Smith +1 more
2019Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens
J. Grondin, D. Duan, Alyssa C. Kirlin, K. Abe +9 more
2017PLoS ONE16 citations Open access
Semantic Scholar
A high-throughput screening platform for enzymes active on mucin-type O-glycoproteins
Jacob F. Wardman, L. Sim, Jennifer Liu, Teresa A. Howard +5 more
2023Nature Chemical Biology15 citations
Semantic Scholar
Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase
C. E. Stevens, Ashley T. Deventer, Paul R. Johnston, Phillip T. Lowe +2 more
2025bioRxiv11 citations Open access
Semantic Scholar
Molecular Characterization of Clinical Rel Mutations and Consequences for Resistance Expression and Fitness in Staphylococcus aureus
Ashley T. Deventer, D. Bryson, Mathew Shortill, A. Boraston +1 more
2022Antimicrobial Agents and Chemotherapy11 citations Open access
Semantic Scholar
Structural evidence for a proline-specific glycopeptide recognition domain in an O-glycopeptidase.
I. Noach, A. Boraston
2020Glycobiology11 citations Open access
Semantic Scholar
Analysis of chondroitin degradation by components of a Bacteroides caccae polysaccharide utilization locus
Bernadette Alvarez, Olivia Canil, Kristin E. Low, A. Hettle +2 more
2025Journal of Biological Chemistry10 citations
Semantic Scholar
A “terminal” case of glycan catabolism: Structural and enzymatic characterization of the sialidases of Clostridium perfringens
Brendon J. Medley, Kristin E. Low, J. Irungu, Linus Kipchumba +9 more
2024Journal of Biological Chemistry10 citations Open access
Semantic Scholar
The structure of a family 110 glycoside hydrolase provides insight into the hydrolysis of α-1,3-galactosidic linkages in λ-carrageenan and blood group antigens
B. E. McGuire, A. Hettle, C. Vickers, D. King +2 more
2020Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Molecular analysis of an enigmatic Streptococcus pneumoniae virulence factor: The raffinose-family oligosaccharide utilization system
J. Hobbs, E. P. Meier, B. Pluvinage, Mackenzie A Mey +1 more
2019Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Pharmacological Chaperones for GCase That Switch Conformation with pH Enhance Enzyme Levels in Gaucher Animal Models.
Andrés Santana, K. Robinson, C. Vickers, Matthew Deen +8 more
2022Angewandte Chemie8 citations
Semantic Scholar
Iminosugar-C-glycosides work as pharmacological chaperones of NAGLU, a glycosidase involved in MPS IIIB rare disease.
Sha Zhu, Y. Jagadeesh, A. Tran, Shuki Imaeda +12 more
2021Chemistry7 citations
Semantic Scholar
Two complementary alpha-fucosidases fromStreptococcus pneumoniaepromote complete degradation of host-derived carbohydrate antigens.
J. Hobbs, B. Pluvinage, M. Robb, Steven P. Smith +1 more
20196 citations
Semantic Scholar
The structure of PfGH50B, an agarase from the marine bacterium Pseudoalteromonas fuliginea PS47.
B. Pluvinage, C. Robb, R. Jeffries, A. Boraston
2020Acta Crystallographica Section F Structural Biology Communications5 citations Open access
Semantic Scholar
Insights into the kappa / iota-carrageenan metabolism pathway of some marinePseudoalteromonasspecies.
A. Hettle, J. Hobbs, B. Pluvinage, C. Vickers +11 more
20195 citations
Semantic Scholar
The complete λ-carrageenan depolymerization cascade from a marine Pseudoalteromonad revealed by structural analysis of the enzymes
C. Vickers, A. Hettle, J. Hobbs, S. Shapiro-Ward +7 more
2025bioRxiv4 citations Open access
Semantic Scholar
Distribution of microbial carrageenan foraging pathways reveals a widespread latent trait within the ruminant intestinal microbiome
J. Tingley, T. O. Andersen, L. Mihalynuk, Xiaohui Xing +14 more
2026Nature Communications3 citations Open access
Semantic Scholar
The structure of a pectin-active family 1 polysaccharide lyase from the marine bacterium Pseudoalteromonas fuliginea
J. Hobbs, A. Boraston
2024Acta Crystallographica Section F Structural Biology Communications3 citations Open access
Semantic Scholar
A dual-color FRET assay for detection and quantitative analysis of O-glycopeptidases.
Olivia Canil, L. Mihalynuk, Nicole K. Thompson, Warren W. Wakarchuk +1 more
2026Methods in Enzymology2 citations
Semantic Scholar
The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae
Emily Knudson-Goerner, A. Boraston
2025Acta Crystallographica Section F Structural Biology Communications2 citations Open access
Semantic Scholar
Global distribution of microbial carrageenan foraging pathways reveals widespread latent traits within the genetic “dark matter” of ruminant intestinal microbiomes
J. Tingley, T. Andersen, L. Mihalynuk, X. Xing +14 more
2025bioRxiv2 citations Open access
Semantic Scholar
Substrate recognition and cleavage by mucin degrading O-glycopeptidases from the gut microbe Bacteroides caccae
B. Pluvinage, Katherine Bourdon, Olivia Canil, Ashley T. Deventer +5 more
2025bioRxiv2 citations Open access
Semantic Scholar
Separation and Visualization of Glycans by Fluorophore-Assisted Carbohydrate Electrophoresis.
M. Robb, J. Hobbs, A. Boraston
2023Methods in molecular biology2 citations
Semantic Scholar
The structure of a family 110 glycoside hydrolase provides insight into the hydrolysis of α-1,3-galactosidic linkages in λ-carrageenan and blood group antigens.
B. E. McGuire, A. Hettle, C. Vickers, D. King +2 more
2020Journal of Biological Chemistry2 citations Open access
Semantic Scholar
Microbial enzymes display sophisticated mechanisms to depolymerize industrially relevant algal polysaccharides.
Emily Knudson-Goerner, A. Boraston
2026Current Opinion in Chemical Biology1 citations Open access
Semantic Scholar
A Fluorogenic Disaccharide Substrate for α-Mannosidases Enables High-Throughput Screening and Identification of an Inhibitor of the GH92 Virulence Factor from Streptococcus pneumoniae.
Sandeep Bhosale, Matthew Deen, Cameron Proceviat, A. Hettle +7 more
2023ACS Chemical Biology1 citations
Semantic Scholar
Chemical tools for inhibition and activity-based profiling of glucocerebrosidase in vitro and in vivo.
Shusheng Wang, Omid Tavassoly, M. A. Chowdhury, Leanne Carter +16 more
2026Cell Chemical Biology0 citations Open access
Semantic Scholar
Clinical Rel mutations that increase basal (p)ppGpp promote conjugal transfer of staphylococcal resistance plasmids
Ashley T. Deventer, Ava Sutherland, Daria Biernacka, Paul R. Johnston +4 more
2026Microbiology0 citations Open access
Semantic Scholar
Polysaccharides characterization of two seaweeds from the Pacific Northwest and evolution of microbial pathways responsible for their consumption in ruminants
D. W. Abbott, J. Tingley, A. Ferrillo, T. O. Andersen +23 more
2026Planta Medica0 citations Open access
Semantic Scholar
Functional conservation of divergent peptidase_M60 O-glycopeptidases in enterococcus
L. Mihalynuk, B. Pluvinage, Olivia Canil, Nicole K. Thompson +2 more
2026Glycobiology0 citations Open access
Semantic Scholar
Clinical stringent response activation promotes conjugal transfer of staphylococcal resistance plasmids
Ashley T. Deventer, Ava Sutherland, Daria Biernacka, Paul R. Johnston +4 more
2025bioRxiv0 citations Open access
Semantic Scholar

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