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E. Hack · SciRah

Researcher profile · Semantic Scholar

E. Hack

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E. Hack — researcher profile on SciRah

h-index: 16
Works: 39
Citations: 1,620

Most-cited papers

Biochemical and functional characterization of the interaction between pentraxin 3 and C1q
A. Nauta, B. Bottazzi, A. Mantovani, G. Salvatori +10 more
2003European Journal of Immunology386 citations
Semantic Scholar
Direct binding of C1q to apoptotic cells and cell blebs induces complement activation
A. Nauta, L. Trouw, M. R. Daha, O. Tijsma +6 more
2002European Journal of Immunology363 citations Open access
Semantic Scholar
International consensus on the diagnosis and management of pediatric patients with hereditary angioedema with C1 inhibitor deficiency
H. Farkas, I. Martínez-Saguer, K. Bork, T. Bowen +80 more
2016Allergy. European Journal of Allergy and Clinical Immunology189 citations Open access
Semantic Scholar
Long-term treatment of hereditary angioedema with attenuated androgens: a survey of a 13-year experience.
M. Cicardi, L. Bergamaschini, Massimo Cugno, E. Hack +2 more
1991Journal of Allergy and Clinical Immunology111 citations
Semantic Scholar
Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor.
Haiwang Tang, L. Ivanciu, N. Popescu, G. Peer +4 more
2007American Journal of Pathology95 citations Open access
Semantic Scholar
Intravenous clusterin administration reduces myocardial infarct size in rats
A. van Dijk, R. Vermond, P. Krijnen, L. J. Juffermans +10 more
2010European Journal of Clinical Investigation61 citations
Semantic Scholar
Plasma levels of C1- inhibitor complexes and cleaved C1- inhibitor in patients with hereditary angioneurotic edema.
M. Cugno, J. Nuijens, E. Hack, A. Eerenberg +3 more
1990Journal of Clinical Investigation58 citations Open access
Semantic Scholar
Heparin-protamine Complexes and C-reactive Protein Induce Activation of the Classical Complement Pathway: Studies in Patients Undergoing Cardiac Surgery and In Vitro
P. Bruins, H. Velthuis, A. Eerenberg-Belmer, A. Yazdanbakhsh +4 more
2000Thrombosis and Haemostasis51 citations
Semantic Scholar
Adrenocorticotropic hormone and cortisol levels in relation to inflammatory response and disease severity in children with meningococcal disease.
J. V. van Woensel, M. Biezeveld, Anne Marie Biesterbos Alders, A. Eerenberg +4 more
2001Journal of Infectious Diseases47 citations Open access
Semantic Scholar
Duraflo II coating of cardiopulmonary bypass circuits reduces complement activation, but does not affect the release of granulocyte enzymes : a European multicentre study.
E. Fosse, S. Thelin, J. Svennevig, Piet G. M. Jansen +11 more
1997European Journal of Cardio-Thoracic Surgery47 citations Open access
Semantic Scholar
Two-stage response to endotoxin infusion into normal human subjects: Correlation of blood phagocyte luminescence with clinical and laboratory markers of the inflammatory, hemostatic response
F. Taylor, P. A. Haddad, E. Hack, A. Chang +6 more
2001Critical Care Medicine42 citations
Semantic Scholar
CXCL4 Links Inflammation and Fibrosis by Reprogramming Monocyte-Derived Dendritic Cells in vitro
S. Silva-Cardoso, Weiyang Tao, C. Angiolilli, A. Lopes +11 more
2020Frontiers in Immunology41 citations Open access
Semantic Scholar
Embracing Complexity beyond Systems Medicine: A New Approach to Chronic Immune Disorders
A. Te Velde, Tjitske Bezema, A. V. van Kampen, A. Kraneveld +15 more
2016Frontiers in Immunology32 citations Open access
Semantic Scholar
Anti-inflammatoryy effects of a p38 Mitogen Activated Protein Kinasee inhibitor during human endotoxemia
J. Sebastiaan, Jeffrey Madwed Weijer, L. Carinaa, Abhya Bo +10 more
27 citations
Semantic Scholar
Clinical similarities among bradykinin-mediated and mast cell-mediated subtypes of non-hereditary angioedema: a retrospective study
K. Schulkes, M. T. van den Elzen, E. Hack, H. Otten +2 more
2015Clinical and Translational Allergy26 citations Open access
Semantic Scholar
The impact of heparin-coated circuits on hemodynamics during and after cardiopulmonary bypass.
R. de Vroege, R. Huybregts, W. van Oeveren, J. van Klarenbosch +6 more
2005Artificial Organs25 citations
Semantic Scholar
Anticoagulant and Membrane-degrading Effects of Secretory (Non-pancreatic) Phospholipase A2 Are Inhibited in Plasma
Didier Billy, Han Speijer, R. F. Zwaal, E. Hack +1 more
2002Thrombosis and Haemostasis10 citations
Semantic Scholar
Clinical studies of recombinant human C1 inhibitor in subjects with hereditary angioedema
J. Nuijens, R. Verdonk, M. V. van Doorn, K. Burggraaf +7 more
20054 citations Open access
Semantic Scholar
Cardioprotective effects of C1-inhibitor after coronary occlusion in dogs Comparison of effects in reperfused and non-reperfused hearts
A. Kleine, M. L. Mullers Boumans, B. Klaassen, A. Koenderman +2 more
20004 citations
Semantic Scholar
CXCL4 links inflammation and fibrosis through transcriptional and epigenetic reprogramming of monocyte-derived cells
S. Silva-Cardoso, Weiyang Tao, C. Angiolilli, A. Lopes +11 more
2019bioRxiv3 citations Open access
Semantic Scholar
Plasma Levels of C 1 Inhibitor Complexes and Cleaved C 1 Inhibitor in Patients with Hereditary Angioneurotic Edema
M. Cugno, J. Nuijens, E. Hack, A. Eerenberg +5 more
20131 citations
Semantic Scholar
Inflammatory Responses in Humans Endotoxin-Mediated Symptoms and IC14, an Anti-CD14 Antibody, Inhibits
T. Axtelle, F. Hoek, S. V. van Deventer, E. Hack +6 more
20011 citations
Semantic Scholar
Complement Dynamics and the Relation to Primary Graft Dysfunction After Clinical Lung Transplantation
R. Novysedlák, L. Bracke, J. Van Slambrouck, A. Barbarossa +15 more
2025The Journal of Heart and Lung Transplantation0 citations
Semantic Scholar
SAT0025 Cxcl4 alters transcriptomic and epigenetic imprinting of dendritic cells thereby driving fibrosis through extracellular matrix formation
S. Silva-Cardoso, Weiyang Tao, C. Angiolilli, A. Lopes +6 more
2018Saturday, 16 JUNE 20180 citations Open access
Semantic Scholar
Embracing Complexity beyond Systems Medicine
J. V. van Montfrans, L. Jans-Beken, A. Kraneveld, H. van Middendorp +15 more
20160 citations
Semantic Scholar
Manifestations locales au cours d’un processus systémique : modèle pathogénique de l’angiœdème à bradykinine (AOBK)
Z. Hofman, A. Relan, S. Zeerleede, C. Drouet +2 more
20150 citations
Semantic Scholar
meningococcal sepsis Cellular origin and procoagulant properties of microparticles in
G. Westendorp, E. Hack, R. Berckmans, Sarah McGregor +2 more
20130 citations
Semantic Scholar
84 Immuno-Safety of Recombinant Human C1 Inhibitor in Patients With Hereditary Angioedema: An Integrated Analysis
E. Hack, A. Relan, L. Kaufman, Rienk Pijpstra
2012The World Allergy Organization Journal0 citations Open access
Semantic Scholar
CHAPTER 11 Complement activation on cell-derived microparticles in myocardial infarction is mediated by immunoglobulin G and not C-reactive protein
P. Marc van der Zee, É. Bíró, K. Yung, R. D. de Winter +4 more
20080 citations
Semantic Scholar
Humann intravenous immunoglobulin preparations degranulate humann neutrophils in vitro
J. Teeling, E. D. de Groot, Anke J.M. Herenberg, G. V. van Mierlo +2 more
20070 citations
Semantic Scholar
The Effects of C1-esterase Inhibition on Cerebral Immune Activation in a Model of Cerebral Embolization in the Rat
Dieleman Jm, F. Delange, N. Diaz, H. Niessen +2 more
20040 citations
Semantic Scholar
UvA-DARE ( Digital Academic Repository ) Heparin coating of extracorporeal circuits inhibits contact activation suring cardiac operations
H. Velthuis, C. Baufreton, P. Jansen, C. Thijs +2 more
20040 citations
Semantic Scholar
sPLA2 potentiates binding of CRP to ischemically challenged cardiomyocytes
R. Nijmeijer, H. Niessen, C. Visser, Y. Lubbers +2 more
20020 citations Open access
Semantic Scholar
The influence of complement inhibition via the classical route on liver I/R injury
B. Heijnen, I. Straatsburg, T. Bos, E. Hack +1 more
20000 citations Open access
Semantic Scholar
COMPLEMENT ACTIVATION BY CRP: MECHANISMS AND POTENTIAL ROLE IN DISEASE.: 48
E. Hack
19990 citations Open access
Semantic Scholar
Cl‐inhibitor: From physiological targets to clinical application.: 283
E. Hack
19970 citations Open access
Semantic Scholar
C1-esterase inhibitor to reduce myocardial damage in acute myocardial infarction
T. Hermens, E. Hack
19940 citations
Semantic Scholar
Proteolytic Inactivation ofPlasmaClInhibitor inSepsis
J. Nuijens, A. Eerenberg-Belmer, C. Huijbregts, R. Felt-Bersma +3 more
19890 citations
Semantic Scholar
DETECTION OF INACTIVATED α2-MACROGLOBULIN (α2M) IN HUMAN PLASMA USING MONOCLONAL ANTIBODIES
J. Abbink, J. Nuijens, C. Huijbregts, E. Hack
1987Thrombosis and Haemostasis0 citations
Semantic Scholar

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