Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

J. Licht · SciRah

Researcher profile · Semantic Scholar

J. Licht

Share profile

J. Licht — researcher profile on SciRah

h-index: 81
Works: 357
Citations: 27K

Most-cited papers

Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator
Jung Kim, Yongik Lee, Xiao-Dong Lu, Bing Song +5 more
2018Cell Reports276 citations Open access
Semantic Scholar
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture
Nevin Yusufova, A. Kloetgen, Matt Teater, Adewola Osunsade +25 more
2020Nature214 citations Open access
Semantic Scholar
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
S. Hogg, Olga Motorna, L. Cluse, Timothy M. Johanson +38 more
2021Molecules and Cells156 citations Open access
Semantic Scholar
A Carcinogen-induced Mouse Model Recapitulates the Molecular Alterations of Human Muscle Invasive Bladder Cancer
D. Fantini, A. Glaser, Kalen Rimar, Yi-Duo Wang +17 more
2018Oncogene127 citations Open access
Semantic Scholar
Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
Ryosuke Shirasaki, G. Matthews, Sara Gandolfi, R. de Matos Simoes +35 more
2021Cell Reports92 citations Open access
Semantic Scholar
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma
Fernanda Faião-Flores, Michael F. Emmons, Michael A. Durante, F. Kinose +9 more
2019Clinical Cancer Research88 citations Open access
Semantic Scholar
A Mutation in Histone H2B Represents A New Class Of Oncogenic Driver
R. Bennett, Aditya Bele, Eliza C. Small, C. Will +14 more
2019Cancer Discovery83 citations Open access
Semantic Scholar
FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML
Yue Sheng, Chunjie Yu, Yin Liu, Chao Hu +8 more
2020Nature Communications82 citations Open access
Semantic Scholar
CTCF boundary remodels chromatin domain and drives aberrant HOX gene transcription in acute myeloid leukemia.
Hua-Cheng Luo, Fei Wang, Jie Zha, Haoli Li +15 more
2018Blood66 citations Open access
Semantic Scholar
HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy
Michael F. Emmons, Fernanda Faião-Flores, Ritin Sharma, R. Thapa +11 more
2019Cancer Research64 citations Open access
Semantic Scholar
USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism.
Johanna Melo-Cardenas, Yuanming Xu, Jun-Cheng Wei, Can Tan +9 more
2018Blood63 citations Open access
Semantic Scholar
Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2
R. Hanley, David Y. Nie, John R. Tabor, Feng-Ling Li +15 more
2023Journal of the American Chemical Society56 citations Open access
Semantic Scholar
Widespread microRNA degradation elements in target mRNAs can assist the encoded proteins
Lu Li, Peike Sheng, Tianqi Li, Christopher J. Fields +6 more
2021Genes & Development56 citations Open access
Semantic Scholar
An Activating Mutation of the NSD2 Histone Methyltransferase Drives Oncogenic Reprogramming in Acute Lymphocytic Leukemia
Alok Swaroop, Jon Oyer, C. Will, Xiaoxiao Huang +10 more
2018Oncogene51 citations Open access
Semantic Scholar
Piperlongumine (PL) conjugates induce targeted protein degradation
J. Pei, Yufeng Xiao, Xin-Gui Liu, Wan-Yi Hu +13 more
2022bioRxiv47 citations Open access
Semantic Scholar
Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma
Raquel Ordoñez, M. Kulis, N. Russiñol, V. Chapaprieta +35 more
2020Genome Research43 citations Open access
Semantic Scholar
Leveraging epigenetics to enhance the efficacy of immunotherapy
J. Licht, R. Bennett
2021Clinical Epigenetics42 citations Open access
Semantic Scholar
BAP1 Loss Promotes Suppressive Tumor Immune Microenvironment via Upregulation of PROS1 in Class 2 Uveal Melanomas
Christopher J. Kaler, J. Dollar, Anthony M. Cruz, J. Kuznetsoff +7 more
2022Cancers37 citations Open access
Semantic Scholar
Genome-Scale Functional Genomics Identify Genes Preferentially Essential for Multiple Myeloma Cells compared to other Neoplasias
R. de Matos Simoes, Ryosuke Shirasaki, Sondra Downey-Kopyscinski, G. Matthews +37 more
2023Nature Cancer35 citations
Semantic Scholar
High-throughput gene screen reveals modulators of nuclear shape
Andrew C Tamashunas, Vincent J Tocco, James H. Matthews, Qiao Zhang +8 more
2020Molecular Biology of the Cell35 citations Open access
Semantic Scholar
Twist-1 is upregulated by NSD2 and contributes to tumour dissemination and an epithelial-mesenchymal transition-like gene expression signature in t(4;14)-positive multiple myeloma
C. Cheong, K. Mrozik, D. Hewett, E. Bell +6 more
2020Cancer Letters34 citations Open access
Semantic Scholar
PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia.
Jian-Ping Li, Julia Hlavka-Zhang, Jonathan H. Shrimp, Crissandra Piper +16 more
2021Cancer Discovery33 citations Open access
Semantic Scholar
Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis–Top-Down Mass Spectrometry
Kevin Jooss, Luis F. Schachner, Rachel Watson, Zachary B. Gillespie +7 more
2021Analytical Chemistry32 citations Open access
Semantic Scholar
The mevalonate pathway is an actionable vulnerability of t(4;14)-positive multiple myeloma
Joseph Longo, P. Smirnov, Zhi-Hua Li, Emily Branchard +8 more
2020Leukemia32 citations Open access
Semantic Scholar
SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck
N. Nigam, B. Bernard, Samantha Sevilla, Sohyoung Kim +34 more
2023Cell Reports26 citations Open access
Semantic Scholar
MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma
Yue Jiang, Ruli Gao, Chun-Xia Cao, L. Forbes +12 more
2019Oral Oncology24 citations Open access
Semantic Scholar
HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers
V. Morozov, A. Riva, Sadia Sarwar, Wan-ju Kim +5 more
2023bioRxiv23 citations Open access
Semantic Scholar
Targeting EZH2 in Multiple Myeloma—Multifaceted Anti-Tumor Activity
M. Alzrigat, H. Jernberg-Wiklund, J. Licht
2018Epigenomes23 citations Open access
Semantic Scholar
Inhibition of cardiomyocyte Sprouty1 protects from cardiac ischemia–reperfusion injury
Tarja Alakoski, J. Ulvila, Raisa Yrjölä, Laura Vainio +4 more
2019Basic Research in Cardiology22 citations Open access
Semantic Scholar
Analysis of Biological Aging and Risks of All-Cause and Cardiovascular Disease–Specific Death in Cancer Survivors
Dongyu Zhang, C. Leeuwenburgh, Dao-Hong Zhou, Yan Gong +3 more
2022JAMA Network Open21 citations Open access
Semantic Scholar
Cancer disparities related to poverty and rurality for 22 top cancers in Florida
Jaclyn M Hall, Sarah M. Szurek, Hee-Kyeung Cho, Yi Guo +4 more
2022Preventive medicine reports19 citations Open access
Semantic Scholar
Defining the NSD2 interactome: PARP1 PARylation reduces NSD2 histone methyltransferase activity and impedes chromatin binding
Xiaoxiao Huang, Richard D. LeDuc, L. Fornelli, Alissa J. Schunter +3 more
2019Journal of Biological Chemistry18 citations Open access
Semantic Scholar
Cancer incidence after asthma diagnosis: Evidence from a large clinical research network in the United States
Yi Guo, Jiang Bian, Zhaoyi Chen, J. Fishe +5 more
2023Cancer Medicine16 citations Open access
Semantic Scholar
Targeting epigenetic mechanisms to overcome venetoclax resistance
G. Prado, C. Kaestner, J. Licht, R. Bennett
2021Biochimica et biophysica acta. Molecular cell research15 citations Open access
Semantic Scholar
Low muscle mass is associated with a higher risk of all-cause and cardiovascular disease-specific mortality in cancer survivors
Dongyu Zhang, Kori A. Spiropoulos, A. Wijayabahu, Demetra D. Christou +13 more
2022Nutrition (Burbank, Los Angeles County, Calif.)14 citations Open access
Semantic Scholar
DNMT3A harboring leukemia-associated mutations directs sensitivity to DNA damage at replication forks
Kartika Venugopal, Yang Feng, P. Nowialis, Huanzhou Xu +23 more
2021bioRxiv14 citations Open access
Semantic Scholar
HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma
S. Sriramareddy, Fernanda Faião-Flores, Michael F. Emmons, Biswarup Saha +7 more
2022Cancer Gene Therapy9 citations Open access
Semantic Scholar
Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia
Barry M. Zee, Kamrine E. Poels, Cong-Hui Yao, K. Kawabata +18 more
2021iScience9 citations Open access
Semantic Scholar
The role of sex and rurality in cancer fatalistic beliefs and cancer screening utilization in Florida
Yi Guo, Sarah M. Szurek, J. Bian, D. Braithwaite +2 more
2021Cancer Medicine9 citations Open access
Semantic Scholar
POU2AF1 As a Master Regulator of Oncogenic Transcription Factor Networks in Myeloma
R. de Matos Simoes, Ryosuke Shirasaki, Hui-Hui Tang, S. Yamano +17 more
20209 citations
Semantic Scholar
A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance of Acute Lymphoblastic Leukemia
Jian-Ping Li, C. Troche, Alok Swaroop, M. Kulis +8 more
2018Blood8 citations Open access
Semantic Scholar
First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival
M. Guijarro, Patrick C. Kellish, Peter E. Dib, Nicholas G. Paciaroni +17 more
2023JCI Insight7 citations Open access
Semantic Scholar
Identification of Piperlongumine (PL) as an new E3 ligase ligand to induce targeted protein degradation
J. Pei, Yufeng Xiao, Xin-Gui Liu, Wan-Yi Hu +14 more
20226 citations
Semantic Scholar
Acquired resistance to EZH2 inhibitor GSK343 promotes the differentiation of human DLBCL cell lines towards an ABC-like phenotype
Samuel E. J. Preston, Audrey Emond, Filippa Pettersson, Daphne Dupéré-Richer +9 more
2022Molecular Cancer Therapeutics6 citations Open access
Semantic Scholar
Oncogenesis by E2A-PBX1 in ALL: RUNX and more.
J. Licht
2020Blood6 citations
Semantic Scholar
NSD2-E1099K Mutation Leads to Glucocorticoid-Resistant B Cell Lymphocytic Leukemia in Mice
Jian-Ping Li, Crissandra Piper, Daphne Dupéré-Richer, Heidi Casellas Roman +7 more
20204 citations Open access
Semantic Scholar
Sprouty1 Controls Genitourinary Development via its N-Terminal Tyrosine.
M. Vaquero, Sara Cuesta, C. Anerillas, Gisela Altés +5 more
2019Journal of the American Society of Nephrology4 citations Open access
Semantic Scholar
Abstract PO-071: Simulation of colorectal cancer clinical trials using real-world data and machine learning
Zhaoyi Chen, Han-Si Zhang, T. George, M. Prosperi +5 more
20213 citations
Semantic Scholar
Functional Characterization of E3 Ligases and Their Regulators: Therapeutic Implications for Development of New Proteolysis-Targeting Chimeric Degraders of Oncoproteins
Ryosuke Shirasaki, Sara Gandolfi, R. de Matos Simoes, G. Matthews +33 more
2019Blood3 citations Open access
Semantic Scholar
Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias - Implications for the Biology and Therapeutic Targeting of Myeloma
R. de Matos Simoes, Ryosuke Shirasaki, Sondra Downey-Kopyscinski, G. Matthews +31 more
2019Blood3 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Bennett×11
Invite
R. Bennett — researcher profile on SciRah
Daphne Dupéré-Richer×7
Invite
Daphne Dupéré-Richer — researcher profile on SciRah
A. Riva×7
Invite
A. Riva — researcher profile on SciRah
Jian-Ping Li×7
Invite
Jian-Ping Li — researcher profile on SciRah

×5

Invite

N. Kelleher — researcher profile on SciRah

Ryosuke Shirasaki×5

Invite

Ryosuke Shirasaki — researcher profile on SciRah

Sara Gandolfi×5

Invite

Sara Gandolfi — researcher profile on SciRah

R. de Matos Simoes×5

Invite

R. de Matos Simoes — researcher profile on SciRah

Olga Dashevsky×5

Invite

Olga Dashevsky — researcher profile on SciRah

Hui-Hui Tang×5

Invite

Hui-Hui Tang — researcher profile on SciRah

Invite

M. Sheffer — researcher profile on SciRah

Sondra Downey-Kopyscinski×5

Invite

Sondra Downey-Kopyscinski — researcher profile on SciRah