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C. Fulcher · SciRah

Researcher profile · Semantic Scholar

C. Fulcher

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C. Fulcher — researcher profile on SciRah

h-index: 31
Works: 69
Citations: 11K

Most-cited papers

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
R. Caspi, Tomer Altman, Joseph M. Dale, K. Dreher +14 more
2009Nucleic Acids Res.2,158 citations Open access
Semantic Scholar
The BioCyc collection of microbial genomes and metabolic pathways
P. Karp, Richard Billington, R. Caspi, C. Fulcher +9 more
2019Briefings Bioinform.883 citations Open access
Semantic Scholar
The MetaCyc database of metabolic pathways and enzymes
R. Caspi, Richard Billington, C. Fulcher, I. Keseler +9 more
2017Nucleic Acids Res.868 citations Open access
Semantic Scholar
The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
R. Caspi, Richard Billington, Luciana Ferrer, Hartmut Foerster +11 more
2015Nucleic Acids Res.818 citations Open access
Semantic Scholar
The MetaCyc Database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases
R. Caspi, Hartmut Foerster, C. Fulcher, Pallavi Kaipa +9 more
2007Nucleic Acids Res.777 citations Open access
Semantic Scholar
The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of Pathway/Genome Databases
R. Caspi, Tomer Altman, Richard Billington, K. Dreher +16 more
2013Nucleic Acids Res.636 citations Open access
Semantic Scholar
EcoCyc: fusing model organism databases with systems biology
I. Keseler, A. Mackie, Martín Peralta-Gil, Alberto Santos-Zavaleta +20 more
2012Nucleic Acids Res.615 citations Open access
Semantic Scholar
EcoCyc: a comprehensive database of Escherichia coli biology
I. Keseler, J. Collado-Vides, Alberto Santos-Zavaleta, Martín Peralta-Gil +17 more
2010Nucleic Acids Res.531 citations Open access
Semantic Scholar
The EcoCyc database: reflecting new knowledge about Escherichia coli K-12
I. Keseler, A. Mackie, Alberto Santos-Zavaleta, Richard Billington +17 more
2016Nucleic Acids Res.510 citations Open access
Semantic Scholar
MetaCyc: a multiorganism database of metabolic pathways and enzymes
R. Caspi, Hartmut Foerster, C. Fulcher, R. Hopkinson +9 more
2005Nucleic Acids Res.495 citations Open access
Semantic Scholar
Proteolytic inactivation of human factor VIII procoagulant protein by activated human protein C and its analogy with factor V.
C. Fulcher, J. E. Gardiner, John H. Griffin, Theodore S. Zimmerman
1984Blood309 citations
Semantic Scholar
A major factor VIII binding domain resides within the amino-terminal 272 amino acid residues of von Willebrand factor.
Paul A. Foster, C. Fulcher, T. Marti, K. Titani +1 more
1987Journal of Biological Chemistry250 citations Open access
Semantic Scholar
Pathway Tools version 19.0 update: software for pathway/genome informatics and systems biology
P. Karp, Mario Latendresse, Suzanne M. Paley, Markus Krummenacker +10 more
2016Briefings Bioinform.240 citations Open access
Semantic Scholar
Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine.
Paul A. Foster, C. Fulcher, R. Houghten, T. Zimmerman
1990Blood190 citations Open access
Semantic Scholar
Pathway Tools version 23.0 update: software for pathway/genome informatics and systems biology
P. Karp, P. Midford, Richard Billington, Anamika Kothari +8 more
2019Briefings Bioinform.183 citations Open access
Semantic Scholar
FVIII inhibitor IgG subclass and FVIII polypeptide specificity determined by immunoblotting.
C. Fulcher, S. de Graaf Mahoney, T. Zimmerman
1987Blood174 citations Open access
Semantic Scholar
Localization of human factor FVIII inhibitor epitopes to two polypeptide fragments.
C. Fulcher, S. de Graaf Mahoney, J. Roberts, C. Kasper +1 more
1985Proceedings of the National Academy of Sciences of the United States of America159 citations Open access
Semantic Scholar
Characterization of the human factor VIII procoagulant protein with a heterologous precipitating antibody.
C. Fulcher, Theodore S. Zimmerman
1982Proceedings of the National Academy of Sciences of the United States of America159 citations Open access
Semantic Scholar
Localization of epitopes for human factor VIII inhibitor antibodies by immunoblotting and antibody neutralization.
D. Scandella, M. Mattingly, S. de Graaf, C. Fulcher
1989Blood146 citations Open access
Semantic Scholar
Inhibition of human natural cytotoxicity by macromolecular antiproteases.
D. Hudig, T. Haverty, C. Fulcher, Doug Redelman +1 more
1981Journal of Immunology133 citations Open access
Semantic Scholar
Epitope mapping of human factor VIII inhibitor antibodies by deletion analysis of factor VIII fragments expressed in Escherichia coli.
D. Scandella, S. Mahoney, M. Mattingly, D. Roeder +2 more
1988Proceedings of the National Academy of Sciences of the United States of America132 citations Open access
Semantic Scholar
An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor.
Paul A. Foster, C. Fulcher, R. Houghten, T. Zimmerman
1988Journal of Biological Chemistry122 citations Open access
Semantic Scholar
Thrombin proteolysis of purified factor viii procoagulant protein: correlation of activation with generation of a specific polypeptide.
C. Fulcher, J. Roberts, Theodore S. Zimmerman
1983Blood115 citations Open access
Semantic Scholar
Localization of the binding regions of a murine monoclonal anti-factor VIII antibody and a human anti-factor VIII alloantibody, both of which inhibit factor VIII procoagulant activity, to amino acid residues threonine351-serine365 of the factor VIII heavy chain.
P. A. Foster, C. Fulcher, R. Houghten, S. de Graaf Mahoney +1 more
1988Journal of Clinical Investigation89 citations Open access
Semantic Scholar
The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
R. Caspi, Tomer Altman, K. Dreher, C. Fulcher +14 more
2011Nucleic Acids Res.84 citations Open access
Semantic Scholar
The EcoCyc Database
P. Karp, Daniel S. Weaver, Suzanne M. Paley, C. Fulcher +18 more
2014EcoSal Plus57 citations Open access
Semantic Scholar
Immunoblot analysis shows changes in factor VIII inhibitor chain specificity in factor VIII inhibitor patients over time.
C. Fulcher, K. Lechner, S. de Graaf Mahoney
1988Blood51 citations
Semantic Scholar
Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopes.
C. Fulcher, J. Roberts, L. Holland, Theodore S. Zimmerman
1985Journal of Clinical Investigation49 citations Open access
Semantic Scholar
An arginine to cysteine amino acid substitution at a critical thrombin cleavage site in a dysfunctional factor VIII molecule.
M. Shima, J. Ware, Akira Yoshioka, Hiromu Fukui +1 more
1989Blood45 citations Open access
Semantic Scholar
Beyond the genome (BTG) is a (PGDB) pathway genome database: HumanCyc
Miles Trupp, Tomer Altman, C. Fulcher, R. Caspi +3 more
2010Genome Biology43 citations Open access
Semantic Scholar
Curation accuracy of model organism databases
I. Keseler, M. Skrzypek, Deepika Weerasinghe, Albert Y. Chen +7 more
2014Database J. Biol. Databases Curation32 citations Open access
Semantic Scholar
The EcoCyc Database
P. Karp, Kit-Ong Wai, Suzanne M. Paley, Richard Billington +15 more
2018EcoSal Plus27 citations
Semantic Scholar
Epitope mapping of human factor VIII inhibitor antibodies by site‐directed mutagenesis of a factor VIII polypeptide
J. Ware, M. J. Macdonald, M. Lo, S. de Graaf +1 more
1992Blood Coagulation and Fibrinolysis25 citations
Semantic Scholar
Purification of factor VIII by monoclonal antibody affinity chromatography.
T. Zimmerman, C. Fulcher
1988Seminars in hematology (Print)25 citations
Semantic Scholar
Localization of the binding site for a factor VIII activity neutralizing antibody to amino acid residues Asp1663-Ser1669.
M. Shima, C. Fulcher, S. de Graaf Mahoney, R. Houghten +1 more
1988Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Factor VIII/von Willebrand factor.
Theodore S. Zimmerman, Z. Ruggeri, C. Fulcher
1983Progress in hematology23 citations
Semantic Scholar
Immunochemistry of factor VIII:C inhibitor antibodies.
C. Fulcher
1991American Journal of Medicine22 citations
Semantic Scholar
A Synthetic Factor VIII Peptide of Eight Amino Acid Residues (1677-1684) Contains the Binding Region of an Anti-Factor VIII Antibody which Inhibits the Binding of Factor VIII to von Willebrand Factor
Paul A. Foster, C. Fulcher, R. Houghten, T. Zimmerman
1990Thrombosis and Haemostasis21 citations
Semantic Scholar
A murine monoclonal anti-factor VIII inhibitory antibody and two human factor VIII inhibitors bind to different areas within a twenty amino acid segment of the acidic region of factor VIII heavy chain.
Paul A. Foster, C. Fulcher, R. Houghten, Sytske de Graaf Mahoney +1 more
1990Blood Coagulation and Fibrinolysis16 citations
Semantic Scholar
BioCyc: Online Resource for Genome and Metabolic Pathway Analysis
R. Caspi, Richard Billington, Hartmut Foerster, C. Fulcher +10 more
2016The FASEB Journal15 citations Open access
Semantic Scholar
Isoelectric focusing of human von Willebrand factor in urea-agarose gels
C. Fulcher, Z. Ruggeri, T. Zimmerman
198312 citations
Semantic Scholar
Apparent molecular weight of purified human factor VIII procoagulant protein compared with purified and plasma factor VIII procoagulant protein antigen
M. Weinstein, C. Fulcher, Leslie E. Chute, Theodore S. Zimmerman
198312 citations
Semantic Scholar
BioCyc: A Genomic and Metabolic Web Portal with Multiple Omics Analytical Tools
R. Caspi, Richard Billington, C. Fulcher, I. Keseler +8 more
2019The FASEB Journal11 citations
Semantic Scholar
Isoelectric focusing of human von Willebrand factor in urea-agarose gels.
C. Fulcher, Z. Ruggeri, T. Zimmerman
1983Blood9 citations Open access
Semantic Scholar
Progress in vascular biology, hemostasis, and thrombosis
Z. Ruggeri, C. Fulcher, J. Ware
19914 citations
Semantic Scholar
A FACTOR VIII BINDING DOMAIN RESIDES WITHIN THE AMINO-TERMINAL 272 AMINO ACID RESIDUES OF VON WILLEBRAND FACTOR
P. A. Foster, C. Fulcher, T. Marti, K. Titani +1 more
1987Thrombosis and Haemostasis4 citations
Semantic Scholar
Structure and function of factor VIII procoagulant protein.
C. Fulcher, T. Zimmerman
1984Progress in clinical and biological research2 citations
Semantic Scholar
Apparent molecular weight of purified human factor VIII procoagulant protein compared with purified and plasma factor VIII procoagulant protein antigen.
M. Weinstein, C. Fulcher, Leslie E. Chute, Theodore S. Zimmerman
1983Blood2 citations
Semantic Scholar
BioCyc: Microbial Genomes and Cellular Networks: The BioCyc system helps scientists navigate the greatly expanding information space of genomes and metabolic information
P. Karp, I. Keseler, Tomer Altman, R. Caspi +9 more
20111 citations
Semantic Scholar
SYNTHETIC PEPTIDE PROBES OF FACTOR VIII IMMUNOLOGY AND FUNCTION
C. Fulcher, R. Houghten, S. de Graaf Mahoney, J. Roberts +1 more
1987Thrombosis and Haemostasis1 citations
Semantic Scholar

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