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Brandon T. Hubbard · SciRah

Researcher profile · Semantic Scholar

Brandon T. Hubbard

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Brandon T. Hubbard — researcher profile on SciRah

h-index: 8
Works: 27
Citations: 360

Most-cited papers

Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis
Traci E. LaMoia, G. Butrico, Hasini A. Kalpage, L. Goedeke +10 more
2022Proceedings of the National Academy of Sciences of the United States of America80 citations Open access
Semantic Scholar
Systemic AAV9 gene therapy improves the lifespan of mice with Niemann-Pick disease, type C1
R. Chandler, Ian M. Williams, Alana L. Gibson, Cristin D. Davidson +5 more
2016Human Molecular Genetics68 citations Open access
Semantic Scholar
Promoterless, Nuclease‐Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia
R. Chandler, L. Venturoni, Jing Liao, Brandon T. Hubbard +10 more
2020Hepatology49 citations Open access
Semantic Scholar
SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat hearts
L. Goedeke, Yina Ma, R. Gaspar, Ali R. Nasiri +19 more
2024Journal of Clinical Investigation48 citations Open access
Semantic Scholar
The mitochondrial calcium uniporter regulates hepatic mitochondrial fat oxidation, and gluconeogenesis by increasing cytosolic calcium and CAMKII
Traci E. LaMoia, Brandon T. Hubbard, Mateus T Guerra, Ali R. Nasiri +9 more
2024Cell Metabolism26 citations Open access
Semantic Scholar
Q-Flux: A method to assess rates of hepatic mitochondrial succinate dehydrogenase, methylmalonyl-CoA mutase, and glutaminase fluxes in vivo
Brandon T. Hubbard, Traci E. LaMoia, L. Goedeke, R. C. Gaspar +4 more
2022Cell Metabolism22 citations Open access
Semantic Scholar
Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice
R. C. Gaspar, Kun Lyu, Brandon T. Hubbard, Brooks P. Leitner +11 more
2022Diabetologia20 citations Open access
Semantic Scholar
Systemic gene therapy for methylmalonic acidemia using the novel adeno-associated viral vector 44.9
R. Chandler, G. Di Pasquale, J. Sloan, Samantha McCoy +5 more
2022Molecular Therapy: Methods & Clinical Development14 citations Open access
Semantic Scholar
MAD2-dependent insulin receptor endocytosis regulates metabolic homeostasis.
Junhee Park, Catherin Hall, Brandon T. Hubbard, Traci E. LaMoia +10 more
2023Diabetes7 citations Open access
Semantic Scholar
Systemic AAV 9 gene therapy improves the lifespan of mice with Niemann-Pick disease , type C 1
R. Chandler, Ian M. Williams, Alana L. Gibson, Cristin D. Davidson +5 more
20167 citations
Semantic Scholar
Cideb knockdown in mice increases mitochondrial fat oxidation and reverses hepatic steatosis and insulin resistance by the plasma membrane sn-1,2-DAGs–PKCε–insulin receptor kinaseT1150 pathway
Jie Zheng, R. Gaspar, Ikki Sakuma, Brandon T. Hubbard +7 more
2025Diabetologia6 citations
Semantic Scholar
Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease.
Rafael Calais Gaspar, Ikki Sakuma, Ali R. Nasiri, Brandon T. Hubbard +8 more
2024American Journal of Physiology. Endocrinology and Metabolism6 citations Open access
Semantic Scholar
Adeno-Associated Viral Gene Therapy Using PHP.B:NPC1 Ameliorates Disease Phenotype in Mouse Model of Niemann-Pick C1 Disease
Alana L. Gibson, Cristin D. Davidson, R. Chandler, B. Deverman +5 more
20173 citations
Semantic Scholar
Hepatic ferredoxin reductase modulates mitochondrial function and iron homeostasis in metabolic dysfunction-associated steatotic liver disease
Tomoaki Tanaka, Ikki Sakuma, R. Gaspar, P. Luukkonen +15 more
2025Research Square2 citations
Semantic Scholar
220-LB: Glucagon Promotes Hepatic Autophagy by AMPK-Mediated mTORC1 Inhibition
Katrine D. Galsgaard, N. J. Wewer Albrechtsen, J. Holst, G. Shulman +6 more
20202 citations
Semantic Scholar
Insulin receptorT1160 phosphorylation mediates renal cortical insulin resistance but not excess gluconeogenesis from glycerol
Brandon T. Hubbard, Yumin Ma, R. Gaspar, Traci E. LaMoia +5 more
2026Nature Communications1 citations Open access
Semantic Scholar
1510-P: Lipid-Induced Renal Cortical Insulin Resistance Perturbs Gluconeogenic and Oxidative Metabolism via an sn-1,2-diacylglycerol-PKCe-Insulin Receptor Kinase Axis In Vivo
Brandon T. Hubbard, R. C. Gaspar, Dong-Yan Zhang, Mario Kahn +2 more
2023Diabetes1 citations
Semantic Scholar
1647-P: Coenzyme A Synthase Knockdown Increases Hepatic Mitochondrial Fat Oxidation and Reduces Hepatic Steatosis and Hepatic Insulin Resistance
R. Gaspar, Ikki Sakuma, Brandon T. Hubbard, Traci E. LaMoia +10 more
2025Diabetes0 citations
Semantic Scholar
1577-P: CIDEB Knockdown Promotes Increased Hepatic Mitochondrial Fat Oxidation and Reverses Hepatic Steatosis and Hepatic Insulin Resistance by the PKCε-Insulin Receptor Kinase Pathway
Jie Zheng, Ali R. Nasiri, R. Gaspar, Brandon T. Hubbard +8 more
2024Diabetes0 citations
Semantic Scholar
192-OR: Lipid-Induced Insulin Resistance in Brown Adipose Tissue Is Mediated by the sn-1,2 DAG-PKCe-IRKT1150 Phosphorylation Pathway
R. C. Gaspar, Brandon T. Hubbard, I. Sakuma, Traci E. LaMoia +2 more
2023Diabetes0 citations
Semantic Scholar
1558-P: The Mitochondrial Calcium Uniporter Regulates Hepatic Mitochondrial Oxidation and Intracellular Redox In Vivo
Traci E. LaMoia, Brandon T. Hubbard, M. Guerra, Russell Goodman +2 more
2023Diabetes0 citations
Semantic Scholar
224-OR: Antisense Oligonucleotide–Mediated Restriction of Mitochondrial Pyruvate Metabolism Limits DNL in High-Fat Fed C57BL6/J Mice
Jordan W. Strober, Lauren M. Paolella, Rebecca Suh, Brandon T. Hubbard +2 more
2022Diabetes0 citations
Semantic Scholar
195-OR: A Novel 13C5 Glutamine Tracer Method (Q Flux) Reveals a Key Role of Succinyl CoA Anaplerosis in Promoting Increased Rates of Hepatic Gluconeogenesis during Hyperglucagonemia
Brandon T. Hubbard, G. Shulman
2022Diabetes0 citations
Semantic Scholar
A Novel Mass-Isotopomer Method Assesses Hepatic Electron Transport Chain and Non-Canonical Anaplerotic Fluxes in vivo
Brandon T. Hubbard, Traci E. LaMoia, L. Goedeke, G. Shulman
2022Social Science Research Network0 citations Open access
Semantic Scholar
501-P: Lower Plasma Membrane Sn-1,2-Diacylglycerol Content and PKCepsilon/theta Activity Explain the Athlete’s Paradox
R. C. Gaspar, Kun Lyu, Brandon T. Hubbard, Brooks P. Leitner +11 more
2021Diabetes0 citations
Semantic Scholar
335-OR: Lipid-Induced Insulin Resistance in the Renal Cortex Is Associated with Plasma Membrane Sn-1,2-diacylglycerol Accumulation and PKCe Translocation
Brandon T. Hubbard, R. C. Gaspar, Dong-Yan Zhang, Mario Kahn +4 more
2021Diabetes0 citations
Semantic Scholar
168. Assaying Hepatic Correction Mediated by Varied AAV Vectors in a Knock-Out Transgenic Mouse Model of Methylmalonic Acidemia (MMA)
Brandon T. Hubbard, R. Chandler, C. Venditti
20160 citations Open access
Semantic Scholar

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Ali R. Nasiri×14
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Ali R. Nasiri — researcher profile on SciRah
Traci E. LaMoia×11
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Traci E. LaMoia — researcher profile on SciRah
G. Shulman×11
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G. Shulman — researcher profile on SciRah
Mario Kahn×11
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Mario Kahn — researcher profile on SciRah

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R. C. Gaspar — researcher profile on SciRah

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R. Gaspar — researcher profile on SciRah

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R. Chandler — researcher profile on SciRah

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C. Venditti — researcher profile on SciRah

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Ikki Sakuma — researcher profile on SciRah

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G. Cline — researcher profile on SciRah

Mark Perelis×5

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Mark Perelis — researcher profile on SciRah

Dong-Yan Zhang×5

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Dong-Yan Zhang — researcher profile on SciRah