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I. Meulenbelt · SciRah

Researcher profile · Semantic Scholar

I. Meulenbelt

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I. Meulenbelt — researcher profile on SciRah

h-index: 55
Works: 307
Citations: 12K

Most-cited papers

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Hunna J. Watson, Zeynep Yilmaz, L. Thornton, Christopher Hübel +206 more
2019Nature Genetics804 citations Open access
Semantic Scholar
Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
C. Boer, K. Hatzikotoulas, L. Southam, L. Stefánsdóttir +151 more
2021Cell433 citations Open access
Semantic Scholar
Osteoarthritis as a disease of the cartilage pericellular matrix
F. Guilak, R. Nims, A. Dicks, Chia-Lung Wu +1 more
2018Matrix Biology410 citations Open access
Semantic Scholar
Metabolomics Profile in Depression: A Pooled Analysis of 230 Metabolic Markers in 5283 Cases With Depression and 10,145 Controls
M. Bot, Y. Milaneschi, Tahani Alshehri, N. Amin +72 more
2019Biological Psychiatry226 citations Open access
Semantic Scholar
RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage
Rodrigo Coutinho de Almeida, Yolande F M Ramos, A. Mahfouz, W. den Hollander +11 more
2018Annals of the Rheumatic Diseases169 citations Open access
Semantic Scholar
Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease
E. B. van den Akker, S. Trompet, J. Barkey Wolf, M. Beekman +36 more
2020Circulation Genomic and Precision Medicine88 citations Open access
Semantic Scholar
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets
M. Tuerlings, M. van Hoolwerff, E. Houtman, E. Suchiman +7 more
2020Arthritis & Rheumatology51 citations Open access
Semantic Scholar
Shared Genetic Risk between Eating Disorder and Substance Use-Related Phenotypes: Evidence from Genome-Wide Association Studies
Melissa A. Munn-Chernoff, E. Johnson, Yi-Ling Chou, J. Coleman +350 more
2020Addiction Biology50 citations Open access
Semantic Scholar
Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene
C. Boer, Michelle S. Yau, S. Rice, Rodrigo Coutinho de Almeida +13 more
2020Annals of the Rheumatic Diseases44 citations Open access
Semantic Scholar
An epigenome-wide view of osteoarthritis in primary tissues
P. Kreitmaier, M. Suderman, L. Southam, Rodrigo Coutinho de Almeida +6 more
2022American Journal of Human Genetics42 citations Open access
Semantic Scholar
Inhibition of KDM7A/B histone demethylases restores H3K79 methylation and protects against osteoarthritis
Reem Assi, C. Cherifi, F. Cornelis, Qiong-Fei Zhou +6 more
2023Annals of the Rheumatic Diseases39 citations Open access
Semantic Scholar
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Hunna J. Watson, Zeynep Yilmaz, L. Thornton, Christopher Hübel +206 more
2019Nature Genetics39 citations Open access
Semantic Scholar
ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone
F. Cornelis, S. Monteagudo, Laura-An K. A. Guns, W. den Hollander +6 more
2018Science Translational Medicine39 citations Open access
Semantic Scholar
High-impact FN1 mutation decreases chondrogenic potential and affects cartilage deposition via decreased binding to collagen type II
M. van Hoolwerff, A. Rodríguez-Ruiz, M. Bouma, H. Suchiman +7 more
2021Science Advances37 citations Open access
Semantic Scholar
Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants
E. Houtman, M. Tuerlings, J. Riechelman, E. Suchiman +6 more
2021Arthritis Research & Therapy35 citations Open access
Semantic Scholar
Cartilage from human-induced pluripotent stem cells: comparison with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells
A. Rodríguez-Ruiz, A. Dicks, M. Tuerlings, K. Schepers +8 more
2021Cell and Tissue Research35 citations Open access
Semantic Scholar
Annotating Transcriptional Effects of Genetic Variants in Disease‐Relevant Tissue: Transcriptome‐Wide Allelic Imbalance in Osteoarthritic Cartilage
W. den Hollander, I. Pulyakhina, C. Boer, N. Bomer +12 more
2019Arthritis & Rheumatology33 citations Open access
Semantic Scholar
Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration
Rodrigo Coutinho de Almeida, A. Mahfouz, H. Mei, E. Houtman +10 more
2020Rheumatology31 citations Open access
Semantic Scholar
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Hunna J. Watson, L. Thornton, Zeynep Yilmaz, J. Baker +173 more
2021Biological Psychiatry Global Open Science30 citations Open access
Semantic Scholar
Vitamin K antagonist anticoagulant usage is associated with increased incidence and progression of osteoarthritis
C. Boer, I. Szilagyi, N. Nguyen, T. Neogi +6 more
2021Annals of the Rheumatic Diseases30 citations Open access
Semantic Scholar
The role of TNFRSF11B in development of osteoarthritic cartilage
Alejandro Rodríguez Ruiz, M. Tuerlings, Ankita Das, R. D. de Almeida +4 more
2021Rheumatology29 citations Open access
Semantic Scholar
Elucidating Epigenetic Regulation by Identifying Functional cis‐Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage
M. van Hoolwerff, Paula I. Metselaar, M. Tuerlings, H. Suchiman +8 more
2020Arthritis & Rheumatology29 citations Open access
Semantic Scholar
Capturing Essential Physiological Aspects of Interacting Cartilage and Bone Tissue with Osteoarthritis Pathophysiology: A Human Osteochondral Unit‐on‐a‐Chip Model
M. Tuerlings, I. Boone, Hossein Eslami Amirabadi, M. Vis +7 more
2022Advanced Materials & Technologies26 citations Open access
Semantic Scholar
Human Osteochondral Explants: Reliable Biomimetic Models to Investigate Disease Mechanisms and Develop Personalized Treatments for Osteoarthritis
E. Houtman, M. van Hoolwerff, N. Lakenberg, E. Suchiman +4 more
2021Rheumatology and Therapy24 citations Open access
Semantic Scholar
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling
N. V. van Vliet, M. Bos, C. Thesing, L. Chaker +40 more
2021BMC Medicine22 citations Open access
Semantic Scholar
Mutation in the CCAL1 locus accounts for bidirectional process of human subchondral bone turnover and cartilage mineralization
A. Rodríguez-Ruiz, M. van Hoolwerff, Sara Sprangers, E. Suchiman +10 more
2022Rheumatology18 citations Open access
Semantic Scholar
Increased WISP1 expression in human osteoarthritic articular cartilage is epigenetically regulated and decreases cartilage matrix production.
M. V. D. van den Bosch, Yolande F M Ramos, W. den Hollander, N. Bomer +7 more
2019Rheumatology18 citations
Semantic Scholar
Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis
Amaya García de Vinuesa, G. Sánchez-Duffhues, E. Blaney-Davidson, A. V. van Caam +7 more
2021Journal of Pathology17 citations Open access
Semantic Scholar
Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls.
M. Verheul, G. Janssen, Arnoud H. de Ru, G. Stoeken-Rijsbergen +10 more
2020Clinical and Experimental Rheumatology17 citations
Semantic Scholar
Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis
Rodrigo Coutinho de Almeida, M. Tuerlings, Y. Ramos, W. den Hollander +5 more
2022medRxiv16 citations Open access
Semantic Scholar
ANP32A represses Wnt signaling across tissues thereby protecting against osteoarthritis and heart disease.
S. Monteagudo, F. Cornelis, Xiang-Dong Wang, A. de Roover +6 more
2022Osteoarthritis and Cartilage16 citations Open access
Semantic Scholar
The miRNA-mRNA interactome of murine induced pluripotent stem cell-derived chondrocytes in response to inflammatory cytokines
Alison K. Ross, R. D. de Almeida, Y. Ramos, Jie-Han Li +2 more
2020The FASEB Journal16 citations Open access
Semantic Scholar
Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants
M. van Hoolwerff, M. Tuerlings, Imke J L Wijnen, H. Suchiman +7 more
2022Rheumatology15 citations Open access
Semantic Scholar
Validity, reliability, responsiveness and feasibility of four hand mobility measures in hand osteoarthritis
F. Kroon, W. Damman, Rani Liu, J. Bijsterbosch +3 more
2018Rheumatology15 citations Open access
Semantic Scholar
Characterizing the secretome of licensed hiPSC-derived MSCs
Yolande F M Ramos, T. Tertel, G. Shaw, S. Staubach +8 more
2022Stem cell research & therapeutics14 citations Open access
Semantic Scholar
Involvement of epigenetics in osteoarthritis.
Rodrigo Coutinho de Almeida, Yolande F M Ramos, I. Meulenbelt
2017Baillière's Best Practice & Research : Clinical Rheumatology13 citations
Semantic Scholar
A human in vitro 3D neo-cartilage model to explore the response of OA risk genes to hyper-physiological mechanical stress
R. G. Timmermans, N. Bloks, M. Tuerlings, M. van Hoolwerff +7 more
2021Osteoarthritis and Cartilage Open12 citations Open access
Semantic Scholar
Variants of FOXO3 and RPA3 genes affecting IGF-1 levels alter the risk of development of primary osteoarthritis.
Iris C. M. Pelsma, K. Claessen, P. Slagboom, D. van Heemst +6 more
2020European Journal of Endocrinology11 citations Open access
Semantic Scholar
Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes
E. Houtman, M. Tuerlings, H. Suchiman, N. Lakenberg +9 more
2022Rheumatology9 citations Open access
Semantic Scholar
A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis
G. Katsoula, J. Steinberg, M. Tuerlings, Rodrigo Coutinho de Almeida +5 more
2022Human Molecular Genetics9 citations Open access
Semantic Scholar
Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers
Y. Ramos, Rodrigo Coutinho de Almeida, N. Lakenberg, E. Suchiman +4 more
2021Biomolecules9 citations Open access
Semantic Scholar
Predicting biological age based on the BBMRI-NL 1H-NMR metabolomics repository
E. B. van den Akker, S. Trompet, J. Barkey Wolf, M. Beekman +36 more
2019bioRxiv9 citations Open access
Semantic Scholar
The first international workshop on the epigenetics of osteoarthritis
I. Meulenbelt, N. Bhutani, W. den Hollander, S. Gay +6 more
2017Connective Tissue Research8 citations Open access
Semantic Scholar
RNA sequencing reveals interacting key determinants of osteoarthritis acting in subchondral bone and articular cartilage
M. Tuerlings, M. van Hoolwerff, E. Houtman, E. Suchiman +7 more
2020bioRxiv7 citations Open access
Semantic Scholar
Development of a human osteochondral construct on a microfluidic chip – to advance functional studies of osteoarthritis risk genes
M. Tuerlings, I. Boone, H. Amirabadi, J. D. den Toonder +2 more
20216 citations Open access
Semantic Scholar
CCN4/WISP1 Promotes Migration of Human Primary Osteoarthritic Chondrocytes
R. G. Timmermans, A. Blom, N. Bloks, R. Nelissen +5 more
2022Cartilage5 citations Open access
Semantic Scholar
Mechanical stress and inflammation have opposite effects on Wnt signaling in human chondrocytes
R. G. Timmermans, A. Blom, R. Nelissen, D. Broekhuis +4 more
2023Journal of Orthopaedic Research4 citations Open access
Semantic Scholar
Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis
M. Tuerlings, M. van Hoolwerff, Jessica M. van Bokkum, H. Suchiman +8 more
2021Rheumatology4 citations Open access
Semantic Scholar
Censoring exosomal crosstalk in osteoarthritis
I. Meulenbelt, Y. Ramos, S. R. Baglio, D. Pegtel
2021Nature Aging3 citations
Semantic Scholar
Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation
Laura M. Huckins, Amanda Dobbyn, Whitney Mcfadden, D. Ruderfer +213 more
2018bioRxiv3 citations Open access
Semantic Scholar

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