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L. Chaker · SciRah

Researcher profile · Semantic Scholar

L. Chaker

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L. Chaker — researcher profile on SciRah

h-index: 49
Works: 179
Citations: 7,200

Most-cited papers

The Rotterdam Study. Design update and major findings between 2020 and 2024
M. Ikram, Brenda C T Kieboom, W. Brouwer, G. Brusselle +14 more
2024European Journal of Epidemiology129 citations Open access
Semantic Scholar
GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer
Wei Zhou, B. Brumpton, O. Kabil, J. Gudmundsson +52 more
2020Nature Communications119 citations Open access
Semantic Scholar
Association of maternal thyroid function with gestational hypertension and preeclampsia: a systematic review and individual participant data meta-analysis
Freddy J. K. Toloza, Arash Derakhshan, Tuija Männistö, S. Bliddal +42 more
2022The Lancet Diabetes and Endocrinology116 citations Open access
Semantic Scholar
Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline
M. Gorski, Bettina Jung, Yong Li, P. Matías-García +127 more
2020Kidney International85 citations Open access
Semantic Scholar
Determinants of Serum Immunoglobulin Levels: A Systematic Review and Meta-Analysis
Samer R. Khan, A. C. van der Burgh, R. Peeters, P. V. van Hagen +2 more
2021Frontiers in Immunology79 citations Open access
Semantic Scholar
Thyroid Function and the Risk of Prediabetes and Type 2 Diabetes
O. H. Roa Dueñas, A. C. van der Burgh, T. Ittermann, S. Ligthart +3 more
2022Journal of Clinical Endocrinology and Metabolism78 citations Open access
Semantic Scholar
Determinants of the Evolution of Kidney Function With Age
A. C. van der Burgh, D. Rizopoulos, M. Ikram, E. Hoorn +1 more
2021Kidney International Reports65 citations Open access
Semantic Scholar
Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications
Rosalie B. T. M. Sterenborg, I. Steinbrenner, Yong Li, Melissa Bujnis +137 more
2024Nature Communications59 citations Open access
Semantic Scholar
Meta-analyses identify DNA methylation associated with kidney function and damage
P. Schlosser, A. Tin, P. Matías-García, C. Thio +109 more
2021Nature Communications59 citations Open access
Semantic Scholar
Hyperthyroidism.
L. Chaker, David S. Cooper, J. P. Walsh, Robin P. Peeters
2024The Lancet57 citations Open access
Semantic Scholar
Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts
Daniel A. DiCorpo, Jessica LeClair, Joanne B. Cole, C. Sarnowski +49 more
2022Diabetes Care56 citations Open access
Semantic Scholar
Thyroid function and mood disorders: a Mendelian Randomization study
Aleksander Kuś, A. D. Kjaergaard, E. Marouli, F. Del Greco M +10 more
2021Thyroid55 citations Open access
Semantic Scholar
The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis
Yan-Ning Xu, Arash Derakhshan, Ola Hysaj, Lea Wildisen +45 more
2023The Lancet Diabetes and Endocrinology52 citations Open access
Semantic Scholar
Determinants and Reference Ranges of Serum Immunoglobulins in Middle-Aged and Elderly Individuals: a Population-Based Study
Samer R. Khan, L. Chaker, M. Ikram, R. Peeters +2 more
2021Journal of Clinical Immunology51 citations Open access
Semantic Scholar
Hypothyroidism: A Review.
L. Chaker, Maria Papaleontiou
2025Journal of the American Medical Association (JAMA)50 citations Open access
Semantic Scholar
Thyroid function affects the risk of stroke via atrial fibrillation: a Mendelian Randomization study.
E. Marouli, Aleksander Kuś, F. Del Greco M, L. Chaker +4 more
2020Journal of Clinical Endocrinology and Metabolism48 citations Open access
Semantic Scholar
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies
M. Gorski, H. Rasheed, A. Teumer, Laurent F. Thomas +172 more
2022Kidney International44 citations Open access
Semantic Scholar
TSH and FT4 Reference Intervals in Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis
Joris A. J. Osinga, Arash Derakhshan, G. Palomaki, G. Ashoor +45 more
2022Journal of Clinical Endocrinology and Metabolism41 citations Open access
Semantic Scholar
Thyroid Function and the Risk of Fibrosis of the Liver, Heart, and Lung in Humans: A Systematic Review and Meta-Analysis
A. Bano, L. Chaker, T. Muka, F. Mattace-raso +4 more
2020Thyroid41 citations Open access
Semantic Scholar
Association of Thyroid Peroxidase Antibodies and Thyroglobulin Antibodies with Thyroid Function in Pregnancy: An Individual Participant Data Meta-Analysis
S. Bliddal, Arash Derakhshan, Yi Xiao, Liang-Miao Chen +36 more
2022Thyroid34 citations Open access
Semantic Scholar
Risk Factors for Thyroid Dysfunction in Pregnancy: An Individual Participant Data Meta-Analysis
Joris A. J. Osinga, Yin-Di Liu, Tuija Männistö, M. Vafeiadi +66 more
2024Thyroid31 citations Open access
Semantic Scholar
Thyroid Function and Physical Activity: A Population-Based Cohort Study
O. H. Roa Dueñas, C. Koolhaas, T. Voortman, Oscar H. Franco +3 more
2020Thyroid30 citations Open access
Semantic Scholar
The Cross-sectional and Longitudinal Association Between Thyroid Function and Depression: A Population-Based Study
O. H. Roa Dueñas, Amy Hofman, A. Luik, M. Medici +2 more
2023Journal of Clinical Endocrinology and Metabolism26 citations Open access
Semantic Scholar
Bidirectional Association Between Kidney Function and Atrial Fibrillation: A Population‐Based Cohort Study
A. C. van der Burgh, S. Geurts, M. Ikram, E. Hoorn +2 more
2022Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease26 citations Open access
Semantic Scholar
Determinants of surgical remission in prolactinomas: a systematic review and meta-analysis.
Kyla Wright, L. Chaker, Donato Pacione, Keren Sam +3 more
2021World Neurosurgery26 citations Open access
Semantic Scholar
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus
A. Tin, P. Schlosser, P. Matías-García, C. Thio +99 more
2021Nature Communications26 citations Open access
Semantic Scholar
TSH and FT4 Reference Interval Recommendations and Prevalence of Gestational Thyroid Dysfunction: Quantification of Current Diagnostic Approaches
Joris A. J. Osinga, Arash Derakhshan, U. Feldt-Rasmussen, Kun Huang +32 more
2023Journal of Clinical Endocrinology and Metabolism23 citations Open access
Semantic Scholar
The role of serum testosterone and dehydroepiandrosterone sulfate in kidney function and clinical outcomes in chronic kidney disease: a systematic review and meta-analysis
A. C. van der Burgh, Samer R. Khan, S. Neggers, E. Hoorn +1 more
2022Endocrine Connections23 citations Open access
Semantic Scholar
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling
N. V. van Vliet, M. Bos, C. Thesing, L. Chaker +40 more
2021BMC Medicine22 citations Open access
Semantic Scholar
Determinants and Clinical Implications of Thyroid Peroxidase Antibodies in Middle-Aged and Elderly Individuals: The Rotterdam Study
Samer R. Khan, R. Peeters, P. V. van Hagen, V. Dalm +1 more
2021Thyroid21 citations Open access
Semantic Scholar
Thyroid Status and Brain Circulation: The Rotterdam Study
L. Fani, Oscar Hernando Roa Dueñas, D. Bos, M. Vernooij +5 more
2021Journal of Clinical Endocrinology and Metabolism21 citations Open access
Semantic Scholar
Disentangling the association between kidney function and atrial fibrillation: A bidirectional Mendelian randomization study.
S. Geurts, A. C. van der Burgh, M. Bos, M. Ikram +5 more
2022International Journal of Cardiology19 citations Open access
Semantic Scholar
Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis
T. Korevaar, Arash Derakhshan, Peter N. Taylor, Marcel E. Meima +43 more
2020Obstetrical and Gynecological Survey19 citations Open access
Semantic Scholar
Association of gestational thyroid function and thyroid autoimmunity with gestational diabetes: a systematic review and individual participant meta-analysis.
Joris A. J. Osinga, Arash Derakhshan, Marianna Karachaliou, Kris G. Poppe +65 more
2025The Lancet Diabetes and Endocrinology18 citations Open access
Semantic Scholar
Serum sodium, cognition and incident dementia in the general population
A. C. van der Burgh, Anissa Pelouto, Sanne S. Mooldijk, A. Zandbergen +3 more
2023Age and Ageing18 citations Open access
Semantic Scholar
Association of Gestational Free and Total Triiodothyronine With Gestational Hypertension, Preeclampsia, Preterm Birth, and Birth Weight: An Individual Participant Data Meta-analysis
Arash Derakhshan, Tuija Männistö, Liang-Miao Chen, Joris A. J. Osinga +35 more
2023Journal of Clinical Endocrinology and Metabolism17 citations Open access
Semantic Scholar
The Association of Serum Immunoglobulins with Risk of Cardiovascular Disease and Mortality: the Rotterdam Study
Samer R. Khan, V. Dalm, M. Ikram, R. Peeters +3 more
2023Journal of Clinical Immunology16 citations Open access
Semantic Scholar
Urinary Prostaglandin E2 Excretion and the Risk of Cardiovascular and Kidney Disease
Frank Geurts, L. Chaker, A. C. van der Burgh, D. Cronin-Fenton +2 more
2024Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease13 citations Open access
Semantic Scholar
Association of habitual coffee consumption and kidney function: A prospective analysis in the Rotterdam Study.
A. C. van Westing, Carolina Ochoa-Rosales, A. C. van der Burgh, L. Chaker +3 more
2022Clinical Nutrition13 citations Open access
Semantic Scholar
Serum Immunoglobulins, Pneumonia Risk, and Lung Function in Middle-Aged and Older Individuals: A Population-Based Cohort Study
Samer R. Khan, Anna Vanoverschelde, L. Lahousse, R. Peeters +4 more
2022Frontiers in Immunology12 citations Open access
Semantic Scholar
Kidney function and the risk of sudden cardiac death in the general population
A. C. van der Burgh, B. Stricker, D. Rizopoulos, M. Ikram +2 more
2022Clinical Kidney Journal10 citations Open access
Semantic Scholar
Thyroid Function and Anthropometric Measures: A Systematic Review and Meta-Analysis.
O. H. Roa Dueñas, Yan-Ning Xu, M. Ikram, R. Peeters +2 more
2024Endocrine Practice8 citations Open access
Semantic Scholar
Circulating metabolites associated with kidney function decline and incident CKD: a multi-platform population-based study
A. C. van der Burgh, S. Geurts, Shahzad Ahmad, M. Ikram +3 more
2023Clinical Kidney Journal8 citations Open access
Semantic Scholar
Sex Differences in the Association Between Serum Testosterone and Kidney Function in the General Population
A. C. van der Burgh, E. Aribas, M. Ikram, M. Kavousi +3 more
2023Kidney International Reports8 citations Open access
Semantic Scholar
Branched-Chain Amino Acids, Alanine, and Thyroid Function: A Cross-Sectional, Nuclear Magnetic Resonance (NMR)-Based Approach from ELSA-Brasil
C. Janovsky, Vandrize Meneghini, W. Tebar, João Roberto Maciel Martins +11 more
2024Metabolites7 citations Open access
Semantic Scholar
Lifetime prevalence and associated factors of itch with skin conditions: Atopic dermatitis, psoriasis and dry skin in individuals aged over 50.
Juliette F. Bollemeijer, Kang Zheng, A. van der Meer, M. Ikram +8 more
2024Clincal and Experimental Dermatology7 citations Open access
Semantic Scholar
Trajectories of kidney function and risk of mortality
A. C. van der Burgh, S. Sedaghat, M. Ikram, E. Hoorn +1 more
2023International Journal of Epidemiology7 citations Open access
Semantic Scholar
Epigenome-Wide Association Study Reveals CpG Sites Associated with Thyroid Function and Regulatory Effects on KLF9
A. Weihs, L. Chaker, T. Martin, K. V. Braun +37 more
2023Thyroid7 citations Open access
Semantic Scholar
Associations between testosterone and knee and hand osteoarthritis among males and females from the general population.
I. Szilagyi, D. Schiphof, L. Chaker, C. Boer +5 more
2025Osteoarthritis and Cartilage6 citations Open access
Semantic Scholar
The Effect of Thiazide Diuretics on Urinary Prostaglandin E2 Excretion and Serum Sodium in the General Population
Frank Geurts, C. Rudolphi, Anissa Pelouto, A. C. van der Burgh +5 more
2024Journal of Clinical Endocrinology and Metabolism6 citations Open access
Semantic Scholar

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R. Peeters×18
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R. Peeters — researcher profile on SciRah
A. C. van der Burgh×14
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A. C. van der Burgh — researcher profile on SciRah
E. Hoorn×11
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E. Hoorn — researcher profile on SciRah
M. Kavousi×9
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A. Teumer — researcher profile on SciRah

Arash Derakhshan×9

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M. Ghanbari — researcher profile on SciRah

Tuija Männistö×8

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