S. Trompet

Most-cited papers

1. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

   A. Mahajan, C. Spracklen, Wei-Hua Zhang, M. Ng +345 more

   2022Nature Genetics616 citations Open access

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2. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

   Ken Suzuki, K. Hatzikotoulas, L. Southam, H. Taylor +360 more

   2024Nature540 citations Open access

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3. Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

   Jacob M. Keaton, Zoha Kamali, Tian Xie, A. Vaez +143 more

   2024Nature Genetics188 citations Open access

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4. Life expectancy associated with different ages at diagnosis of diabetes: 23 million person-years of observation

   S. Kaptoge, Srk Seshasai, L. Sun, M. Walker +223 more

   2023The Lancet Diabetes and Endocrinology115 citations Open access

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5. Sex differences in dementia risk and risk factors: Individual‐participant data analysis using 21 cohorts across six continents from the COSMIC consortium

   Jessica Gong, K. Harris, D. Lipnicki, É. Castro-Costa +54 more

   2023Alzheimer's & Dementia113 citations Open access

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6. Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries

   A. Mishra, R. Malik, T. Hachiya, Tuuli Jürgenson +198 more

   2022Nature113 citations Open access

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7. Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis

   C. Reith, David Preiss, L. Blackwell, J. Emberson +128 more

   2024The Lancet Diabetes and Endocrinology108 citations Open access

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8. Chemotherapy-Related Toxic Effects and Quality of Life and Physical Functioning in Older Patients

   J. Baltussen, N. D. de Glas, Y. van Holstein, M. van der Elst +12 more

   2023JAMA Network Open89 citations Open access

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9. Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications

   Rosalie B. T. M. Sterenborg, I. Steinbrenner, Yong Li, Melissa Bujnis +137 more

   2024Nature Communications59 citations Open access

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10. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

    S. Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka +496 more

    2022Genome Biology59 citations Open access

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11. The optimal healthy ranges of thyroid function defined by the risk of cardiovascular disease and mortality: systematic review and individual participant data meta-analysis

    Yan-Ning Xu, Arash Derakhshan, Ola Hysaj, Lea Wildisen +45 more

    2023The Lancet Diabetes and Endocrinology52 citations Open access

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12. Polygenic prediction of body mass index and obesity through the life course and across ancestries

    R. Smit, K. Wade, Qin Hui, J. Arias +496 more

    2025Nature Medicine51 citations Open access

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13. Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes

    Albert Henry, Xiaodong Mo, C. Finan, M. Chaffin +177 more

    2025Nature Genetics48 citations Open access

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14. Multiplex Apolipoprotein Panel Improves Cardiovascular Event Prediction and Cardiovascular Outcome by Identifying Patients Who Benefit From Targeted PCSK9 Inhibitor Therapy

    E. Reijnders, P. Bossuyt, J. Jukema, L. Ruhaak +14 more

    2025Arteriosclerosis, Thrombosis and Vascular Biology44 citations Open access

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15. Genetic insights into resting heart rate and its role in cardiovascular disease

    Y. J. van de Vegte, R. Eppinga, M. Yldau van der Ende, Y. Hagemeijer +188 more

    2023Nature Communications34 citations Open access

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16. Lifestyle and clinical risk factors in relation with the prevalence of diabetes in the Indonesian urban and rural populations: The 2018 Indonesian Basic Health Survey

    Farid Kurniawan, F. S. Sigit, S. Trompet, Em Yunir +5 more

    2024Preventive medicine reports33 citations Open access

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17. Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials

    C. Reith, L. Blackwell, J. Emberson, D. Preiss +131 more

    2026The Lancet28 citations Open access

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18. Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications

    Ken Suzuki, K. Hatzikotoulas, L. Southam, H. Taylor +347 more

    2023medRxiv27 citations Open access

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19. Towards optimal use of antithrombotic therapy of people with cancer at the end of life: A research protocol for the development and implementation of the SERENITY shared decision support tool.

    J. Goedegebuur, D. Abbel, S. Accassat, W. Achterberg +75 more

    2023Thrombosis Research26 citations Open access

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20. Toxicity in Older Patients with Cancer Receiving Immunotherapy: An Observational Study

    Estelle Tran Van Hoi, S. Trompet, Y. van Holstein, F. van den Bos +9 more

    2024Drugs & Aging24 citations Open access

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21. Lifestyle and incident dementia: A COSMIC individual participant data meta‐analysis

    Stephanie Van Asbroeck, S. Köhler, M. V. van Boxtel, D. Lipnicki +60 more

    2024Alzheimer's & Dementia24 citations Open access

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22. A genetic association study of circulating coagulation Factor VIII and von Willebrand Factor levels.

    P. D. de Vries, Paula Reventun, Michael R. Brown, Adam S. Heath +91 more

    2024Blood20 citations Open access

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23. Association of cognitive function with increased risk of cancer death and all-cause mortality: Longitudinal analysis, systematic review, and meta-analysis of prospective observational studies

    Somayeh Rostamian, S. le Cessie, K. Marijt, J. Jukema +5 more

    2022PLoS ONE17 citations Open access

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24. Adherence to the healthy lifestyle guideline in relation to the metabolic syndrome: Analyses from the 2013 and 2018 Indonesian national health surveys

    F. S. Sigit, S. Trompet, D. Tahapary, D. Harbuwono +3 more

    2022Preventive medicine reports17 citations Open access

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25. The impact of statin use on sepsis mortality.

    Mo-Han Li, R. Noordam, S. Trompet, E. M. Winter +4 more

    2024Journal of Clinical Lipidology16 citations Open access

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26. Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease

    William J. Young, J. Haessler, J. Benjamins, Linda Repetto +90 more

    2023Nature Communications16 citations Open access

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27. Increased 1H-NMR metabolomics-based health score associates with declined cognitive performance and functional independence in older adults at risk of cardiovascular disease

    M. Zonneveld, Nour Al Kuhaili, S. Mooijaart, P. Slagboom +3 more

    2023GeroScience16 citations Open access

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28. Weight loss, visit-to-visit body weight variability and cognitive function in older individuals

    M. Zonneveld, R. Noordam, B. Sabayan, D. Stott +5 more

    2023Age and Ageing14 citations Open access

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29. Author Correction: The power of genetic diversity in genome-wide association studies of lipids

    Sarah E. Graham, S. Clarke, Kuan-Han H. Wu, S. Kanoni +496 more

    2023Nature12 citations Open access

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30. Exploring the possible causal effects of cardiac blood biomarkers in dementia and cognitive performance: a Mendelian randomization study

    M. Zonneveld, S. Trompet, J. Jukema, R. Noordam

    2023GeroScience11 citations Open access

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31. Temporal dynamics of depressive symptoms and cognitive decline in the oldest old: dynamic time warp analysis of the Leiden 85-plus study

    A. J. C. van der Slot, A. Bertens, S. Trompet, S. Mooijaart +3 more

    2024Age and Ageing10 citations Open access

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32. NMR metabolomics-guided DNA methylation mortality predictors

    D. Bizzarri, M. Reinders, L. Kuiper, M. Beekman +71 more

    2024EBioMedicine10 citations Open access

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33. The performance of metabolomics-based prediction scores for mortality in older patients with solid tumors

    Y. van Holstein, S. Mooijaart, M. van Oevelen, F. V. van Deudekom +15 more

    2024GeroScience10 citations Open access

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34. Frailty and treatment decisions in older patients with vulvar cancer: A single-center cohort study.

    E. Gans, J. Portielje, O. Dekkers, C. D. de Kroon +7 more

    2023Journal of Geriatric Oncology10 citations Open access

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35. Cardiac Troponin, Cognitive Function, and Dementia: A Systematic Review

    M. Zonneveld, Denise Abbel, S. le Cessie, J. Jukema +2 more

    2023Aging and Disease9 citations Open access

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36. Normal range CAG repeat size variations in the HTT gene are associated with an adverse lipoprotein profile partially mediated by body mass index

    T. Faquih, N. A. Aziz, S. L. Gardiner, R. Li-Gao +8 more

    2023Human Molecular Genetics9 citations Open access

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37. Impact of immune-related adverse events on quality of life and physical functioning in older patients with solid tumors treated with immune checkpoint inhibitors.

    A. Özkan, K. de Joode, E. Kapiteijn, M. Slingerland +14 more

    2025European Journal of Cancer8 citations Open access

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38. Temporal changes in characteristics and external validity of randomized controlled trials in older people from 2012 to 2019

    Estelle van Eijk, Yanna M. van der Spek, F. V. van Deudekom, F. van den Bos +2 more

    2023BMC Geriatrics8 citations Open access

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39. Risk assessment and management strategies in older patients with acute pulmonary embolism.

    Dieuwke Luijten, D. Abbel, S. Cannegieter, Jeroen C. J. Eikenboom +8 more

    2024Journal of Thrombosis and Haemostasis7 citations Open access

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40. Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.

    J. Huffman, J. Nicholas, Julie Hahn, Adam S. Heath +132 more

    2024Blood7 citations Open access

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41. Predicting mortality and visualizing health care spending by predicted mortality in Danes over age 65

    A. V. Hansen, L. Mortensen, C. Ekstrøm, S. Trompet +1 more

    2023Scientific Reports7 citations Open access

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42. The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

    S. Trompet, I. Postmus, H. Warren, R. Noordam +13 more

    2022Frontiers in Pharmacology7 citations Open access

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43. Preparing for future pandemics: frailty associates with mortality in hospitalised older people during the entire COVID-19 pandemic, a Dutch multicentre cohort study

    B. V. van Raaij, R. Noordam, Rosalinde A. L. Smits, Veerle M. G. T. H. van der Klei +28 more

    2024European Geriatric Medicine6 citations Open access

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44. Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.

    J. Huffman, J. Nicolas, Julie Hahn, Adam S. Heath +132 more

    2023medRxiv6 citations Open access

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45. Prediction of incident heart failure in individuals without prior cardiovascular disease: the SCORE2-HF risk model

    Stephen Spencer J Tessa Wen Jennifer S Laura Mari Nordbø C Kaptoge Keene Reitsma Shi Lees Lõo Gynnild Chilala, S. Kaptoge, S. Keene, T. Reitsma +69 more

    2026European Heart Journal5 citations Open access

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46. Differences in characteristics and outcomes of older patients hospitalized for COVID-19 after introduction of vaccination

    Rosalinde A. L. Smits, B. V. van Raaij, S. Trompet, C. V. D. van der Linden +8 more

    2024European Geriatric Medicine5 citations Open access

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47. Pravastatin reduces all-cause mortality in elderly individuals at risk of liver fibrosis: Post hoc analysis of the PROSPER trial

    Vivian D. de Jong, W. Theel, Manuel Castro Cabezas, Diederick E. Grobbee +2 more

    2025JHEP Reports4 citations Open access

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48. Risk of cardiovascular disease in elderly subjects with obesity and liver fibrosis and the potential benefit of statin treatment

    W. Theel, Vivian D. de Jong, Manuel Castro Cabezas, Diederick E. Grobbee +2 more

    2024European Journal of Clinical Investigation4 citations Open access

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49. Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes.

    S. Kwak, R. Hernandez-Cancela, Daniel A. DiCorpo, David E. Condon +63 more

    2024Diabetes Care4 citations Open access

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50. The association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors: A systematic review.

    Y. van Holstein, P. Janne E. van den Berkmortel, S. Trompet, D. van Heemst +8 more

    2023Journal of Geriatric Oncology4 citations Open access

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