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J. Gertz · SciRah

Researcher profile · Semantic Scholar

J. Gertz

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J. Gertz — researcher profile on SciRah

h-index: 39
Works: 108
Citations: 12K

Most-cited papers

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia
Stephen G. Landt, G. Marinov, A. Kundaje, P. Kheradpour +43 more
2012Genome Research1,895 citations Open access
Semantic Scholar
Architecture of the human regulatory network derived from ENCODE data
M. Gerstein, A. Kundaje, M. Hariharan, Stephen G. Landt +52 more
2012Nature1,498 citations Open access
Semantic Scholar
Dynamic DNA methylation across diverse human cell lines and tissues
K. Varley, J. Gertz, K. Bowling, S. Parker +9 more
2013Genome Research709 citations Open access
Semantic Scholar
Widespread plasticity in CTCF occupancy linked to DNA methylation
Hao Wang, Matthew T. Maurano, H. Qu, K. Varley +10 more
2012Genome Research605 citations Open access
Semantic Scholar
MYC drives progression of small cell lung cancer to a variant neuroendocrine subtype with vulnerability to Aurora kinase inhibition
G. Mollaoglu, M. R. Guthrie, S. Böhm, J. Brägelmann +25 more
2017Cancer Cell536 citations Open access
Semantic Scholar
From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing
G. Marinov, B. Williams, K. Mccue, G. Schroth +3 more
2014Genome Research467 citations Open access
Semantic Scholar
MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate
A. Ireland, Alexi M. Micinski, D. W. Kastner, Bingqian Guo +18 more
2020Cancer Cell449 citations Open access
Semantic Scholar
A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology
Katrin P. Guillen, Maihi Fujita, A. Butterfield, Sandra D. Scherer +38 more
2022Nature Cancer376 citations Open access
Semantic Scholar
Distinct properties of cell type-specific and shared transcription factor binding sites
J. Gertz, Daniel Savic, K. Varley, E. Partridge +6 more
2013Molecules and Cells340 citations Open access
Semantic Scholar
Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation
J. Gertz, K. Varley, Timothy E. Reddy, K. Bowling +5 more
2011PLoS Genetics308 citations Open access
Semantic Scholar
Estrogen Signaling in Endometrial Cancer: a Key Oncogenic Pathway with Several Open Questions
Adriana C. Rodriguez, Zannel Blanchard, K. Maurer, J. Gertz
2019Hormones & cancer269 citations Open access
Semantic Scholar
CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice
Ya Guo, K. Monahan, Haiyang Wu, J. Gertz +5 more
2012Proceedings of the National Academy of Sciences of the United States of America261 citations Open access
Semantic Scholar
Post-mortem molecular profiling of three psychiatric disorders
R. Ramaker, K. Bowling, Brittany N. Lasseigne, M. Hagenauer +16 more
2016Genome Medicine197 citations Open access
Semantic Scholar
The lineage defining transcription factors SOX2 and NKX2-1 determine lung cancer cell fate and shape the tumor immune microenvironment
G. Mollaoglu, Alex Jones, S. Wait, A. Mukhopadhyay +17 more
2018Immunity190 citations Open access
Semantic Scholar
Recurrent read-through fusion transcripts in breast cancer
K. Varley, J. Gertz, Brian S. Roberts, Nicholas S. Davis +9 more
2014Breast Cancer Research and Treatment174 citations Open access
Semantic Scholar
Effects of sequence variation on differential allelic transcription factor occupancy and gene expression
Timothy E. Reddy, J. Gertz, Florencia Pauli, Katerina S. Kucera +10 more
2012Genome Research170 citations Open access
Semantic Scholar
GIGGLE: a search engine for large-scale integrated genome analysis
R. Layer, Brent S. Pedersen, Tonya DiSera, G. Marth +2 more
2017Nature Methods169 citations Open access
Semantic Scholar
MYC-driven small cell lung cancer is metabolically distinct and vulnerable to arginine depletion
Milind D. Chalishazar, S. Wait, Fang Huang, A. Ireland +17 more
2019Clinical Cancer Research152 citations Open access
Semantic Scholar
The Hypersensitive Glucocorticoid Response Specifically Regulates Period 1 and Expression of Circadian Genes
Timothy E. Reddy, J. Gertz, Gregory E. Crawford, M. Garabedian +1 more
2012Molecular and Cellular Biology142 citations Open access
Semantic Scholar
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner
J. Gertz, Timothy E. Reddy, K. Varley, M. Garabedian +1 more
2012Genome Research137 citations Open access
Semantic Scholar
Cooperative Dynamics of AR and ER Activity in Breast Cancer
Nicholas C. D'Amato, M. Gordon, Beatrice L Babbs, N. Spoelstra +10 more
2016Molecular Cancer Research122 citations Open access
Semantic Scholar
IκB kinase ε (IKKε) regulates the balance between type I and type II interferon responses
Sze-Ling Ng, Brad A. Friedman, Sonja Schmid, J. Gertz +3 more
2011Proceedings of the National Academy of Sciences of the United States of America118 citations Open access
Semantic Scholar
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers
J. Carleton, Kristofer C. Berrett, J. Gertz
2017Cell Systems103 citations Open access
Semantic Scholar
RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long‐term survival and reveals a role for ANGPTL4
Marie K. Kirby, R. Ramaker, J. Gertz, Nicholas S. Davis +12 more
2016Molecular Oncology94 citations Open access
Semantic Scholar
Early de novo DNA methylation and prolonged demethylation in the muscle lineage
Koji Tsumagari, Carl Baribault, Jolyon Terragni, K. Varley +9 more
2013Epigenetics93 citations Open access
Semantic Scholar
Transposase mediated construction of RNA-seq libraries.
J. Gertz, K. Varley, Nicholas S. Davis, B. Baas +4 more
2012Genome Research88 citations Open access
Semantic Scholar
Clinical and Genomic Crosstalk between Glucocorticoid Receptor and Estrogen Receptor α In Endometrial Cancer
Jeffery M. Vahrenkamp, Chieh‐Hsiang Yang, Adriana C. Rodriguez, A. Almomen +7 more
2017bioRxiv67 citations Open access
Semantic Scholar
Genomic regulation of invasion by STAT3 in triple negative breast cancer
Joy M. McDaniel, K. Varley, J. Gertz, Daniel Savic +18 more
2016OncoTarget67 citations Open access
Semantic Scholar
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells
Adriana C. Rodriguez, Jeffery M. Vahrenkamp, Kristofer C. Berrett, K. Clark +7 more
2019bioRxiv66 citations Open access
Semantic Scholar
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration
Niloofar Farhang, Matthew Ginley-Hidinger, Kristofer C. Berrett, J. Gertz +2 more
2019Human Gene Therapy60 citations Open access
Semantic Scholar
Environment-specific combinatorial cis-regulation in synthetic promoters
J. Gertz, B. Cohen
2009Molecular Systems Biology57 citations Open access
Semantic Scholar
Hotspot ESR1 mutations are multimodal and contextual modulators of breast cancer metastasis
Zhe-Qi Li, Yang Wu, Megan E. Yates, N. Tasdemir +35 more
2022Cancer Research51 citations Open access
Semantic Scholar
Estrogen receptor alpha mutations in breast cancer cells cause gene expression changes through constant activity and secondary effects
Spencer Arnesen, Zannel Blanchard, M. Williams, Kristofer C. Berrett +4 more
2020Cancer Research50 citations Open access
Semantic Scholar
CRISPR Epigenome Editing of AKAP150 in DRG Neurons Abolishes Degenerative IVD-Induced Neuronal Activation.
J. Stover, Niloofar Farhang, Kristofer C. Berrett, J. Gertz +2 more
2017Molecular Therapy45 citations Open access
Semantic Scholar
Brd4-bound enhancers drive cell-intrinsic sex differences in glioblastoma
Najla Kfoury, Zong-Tai Qi, B. Prager, Michael N. Wilkinson +9 more
2017Proceedings of the National Academy of Sciences of the United States of America42 citations Open access
Semantic Scholar
Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation
Daniel Savic, R. Ramaker, Brian S. Roberts, Emma C. Dean +6 more
2016Genome Medicine42 citations Open access
Semantic Scholar
Reciprocal regulation of pancreatic ductal adenocarcinoma growth and molecular subtype by HNF4α and SIX1/4
Soledad A. Camolotto, Veronika K. Belova, Luke A. Torre-Healy, Jeffery M. Vahrenkamp +7 more
2019Gut41 citations Open access
Semantic Scholar
Estrogen-independent molecular actions of mutant estrogen receptor 1 in endometrial cancer
Zannel Blanchard, Jeffery M. Vahrenkamp, Kristofer C. Berrett, Spencer Arnesen +1 more
2019Genome Research39 citations Open access
Semantic Scholar
Allele-specific distribution of RNA polymerase II on female X chromosomes.
Katerina S. Kucera, Timothy E. Reddy, Florencia Pauli, J. Gertz +3 more
2011Human Molecular Genetics39 citations Open access
Semantic Scholar
Steroid hormone receptor and infiltrating immune cell status reveals therapeutic vulnerabilities of ESR1 mutant breast cancer.
M. Williams, N. Spoelstra, Spencer Arnesen, Kathleen I. O'Neill +14 more
2020Cancer Research38 citations Open access
Semantic Scholar
A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer
Yan-Li Liu, Zhong Wu, Jin Zhou, D. K. Ramadurai +13 more
2021Nature Communications35 citations Open access
Semantic Scholar
Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites
Daniel Savic, Brian S. Roberts, J. Carleton, E. Partridge +5 more
2015Genome Research35 citations Open access
Semantic Scholar
NHR-14 loss of function couples intestinal iron uptake with innate immunity in C. elegans through PQM-1 signaling
Malini Rajan, Cole P. Anderson, Paul M. Rindler, S. Romney +3 more
2019eLife33 citations Open access
Semantic Scholar
Mapping genome-wide transcription factor binding sites in frozen tissues
Daniel Savic, J. Gertz, P. Jain, Gregory M. Cooper +1 more
2013Epigenetics & Chromatin32 citations Open access
Semantic Scholar
Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design
Lukas M. Weber, Ariel A. Hippen, Peter F. Hickey, Kristofer C. Berrett +4 more
2020bioRxiv31 citations Open access
Semantic Scholar
Synergistic CRISPRa-Regulated Chondrogenic Extracellular Matrix Deposition Without Exogenous Growth Factors
Niloofar Farhang, Bryton Davis, J. Weston, Matthew Ginley-Hidinger +2 more
2020Tissue Engineering. Part A25 citations Open access
Semantic Scholar
Research resource: enhanced genome-wide occupancy of estrogen receptor α by the cochaperone p23 in breast cancer cells.
N. Simpson, J. Gertz, Keren Imberg, R. Myers +1 more
2012Molecular Endocrinology23 citations Open access
Semantic Scholar
A Positive Feedback Loop Between TGFβ and Androgen Receptor Supports Triple-Negative Breast Cancer Anoikis Resistance.
Emmanuel Rosas, J. Roberts, Kathleen I. O'Neill, J. Christenson +6 more
2020Endocrinology20 citations Open access
Semantic Scholar
Improved survival among colon cancer patients with increased differentially expressed pathways
M. Slattery, J. Herrick, L. Mullany, J. Gertz +1 more
2015BMC Medicine20 citations Open access
Semantic Scholar
Comprehensive evaluation and efficient classification of BRCA1 RING domain missense substitutions.
K. Clark, A. Paquette, K. Tao, R. Bell +13 more
2022American Journal of Human Genetics19 citations Open access
Semantic Scholar

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