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R. McIntyre · SciRah

Researcher profile · Semantic Scholar

R. McIntyre

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R. McIntyre — researcher profile on SciRah

h-index: 21
Works: 39
Citations: 4,095

Most-cited papers

Mouse genomic variation and its effect on phenotypes and gene regulation
T. Keane, L. Goodstadt, P. Danecek, Michael A. White +37 more
2011Nature1,560 citations Open access
Semantic Scholar
Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes
Jacqueline K. White, Anna-Karin B. Gerdin, N. Karp, E. Ryder +126 more
2013Cell503 citations Open access
Semantic Scholar
PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice
George Poulogiannis, R. McIntyre, Maria Dimitriadi, J. Apps +7 more
2010Proceedings of the National Academy of Sciences of the United States of America243 citations Open access
Semantic Scholar
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi Anemia
Gerry P. Crossan, L. van der Weyden, I. V. Rosado, Frédéric Langevin +9 more
2011Nature Genetics218 citations Open access
Semantic Scholar
Quantifying the contribution of recessive coding variation to developmental disorders
H. Martin, W. Jones, R. McIntyre, G. Sanchez-Andrade +35 more
2017Science192 citations Open access
Semantic Scholar
Somatic Evolution in Non-neoplastic IBD-Affected Colon
S. Olafsson, R. McIntyre, T. Coorens, T. Butler +15 more
2020Cell179 citations Open access
Semantic Scholar
High levels of RNA-editing site conservation amongst 15 laboratory mouse strains
P. Danecek, Christoffer Nellåker, R. McIntyre, J. Buendia-Buendia +6 more
2012Genome Biology164 citations Open access
Semantic Scholar
Genome-wide association of multiple complex traits in outbred mice by ultra low-coverage sequencing
J. Nicod, R. Davies, Na Cai, C. Hassett +38 more
2016Nature Genetics133 citations Open access
Semantic Scholar
The activating mutation R201C in GNAS promotes intestinal tumourigenesis in ApcMin/+ mice via activation of Wnt and ERK1/2 MAPK pathways
Catherine H. Wilson, R. McIntyre, Mark J. Arends, David J. Adams
2010Oncogene110 citations Open access
Semantic Scholar
The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation.
A. Nijnik, S. Clare, C. Hale, C. Raisen +14 more
2012Blood102 citations Open access
Semantic Scholar
Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome
R. McIntyre, Pavithra Lakshminarasimhan Chavali, O. Ismail, D. Carragher +19 more
2012PLoS Genetics98 citations Open access
Semantic Scholar
Mouse models of colorectal cancer as preclinical models
R. McIntyre, Simon J. A. Buczacki, M. Arends, David John Adams
2015Bioessays88 citations Open access
Semantic Scholar
A high-throughput in vivo micronucleus assay for genome instability screening in mice
G. Balmus, N. Karp, B. Ng, S. Jackson +2 more
2014Nature Protocols71 citations Open access
Semantic Scholar
Genetic determinants of micronucleus formation in vivo
D. Adams, B. Barlas, R. McIntyre, I. Salguero +82 more
2024Nature55 citations Open access
Semantic Scholar
Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation
Catherine H. Wilson, Catriona Crombie, L. van der Weyden, George Poulogiannis +12 more
2012EMBO Journal54 citations Open access
Semantic Scholar
Mcph1-Deficient Mice Reveal a Role for MCPH1 in Otitis Media
Jing Chen, N. Ingham, S. Clare, C. Raisen +9 more
2013PLoS ONE53 citations Open access
Semantic Scholar
MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance
Matthew J. Sale, K. Balmanno, J. Saxena, Eiko Ozono +15 more
2019Nature Communications52 citations Open access
Semantic Scholar
Copy number variant detection in inbred strains from short read sequence data
J. Simpson, R. McIntyre, D. Adams, R. Durbin
2009Bioinform.52 citations Open access
Semantic Scholar
Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1
L. van der Weyden, M. Arends, A. Rust, George Poulogiannis +2 more
2012Molecular Cancer44 citations Open access
Semantic Scholar
Gut mucosa dissociation protocols influence cell type proportions and single-cell gene expression levels
W. U. Uniken Venema, Aarón D. Ramírez-Sánchez, E. Bigaeva, S. Withoff +8 more
2022Scientific Reports40 citations Open access
Semantic Scholar
Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity
L. van der Weyden, A. Rust, R. McIntyre, C. D. Robles-Espinoza +7 more
2012Oncogene31 citations Open access
Semantic Scholar
Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine
Nicola J. Wyatt, H. Watson, C. Anderson, Nicholas A. Kennedy +46 more
2024BMJ Open15 citations Open access
Semantic Scholar
Cancer gene discovery in the mouse.
R. McIntyre, L. van der Weyden, D. Adams
2012Current Opinion in Genetics and Development12 citations
Semantic Scholar
High levels of RNA-editing site conservation amongst 15 laboratory mouse strains
P. Danecek, Christoffer Nellåker, R. McIntyre, J. Buendia-Buendia +6 more
2012Genome Biology11 citations Open access
Semantic Scholar
A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice
R. McIntyre, J. Nicod, C. D. Robles-Espinoza, J. Maciejowski +9 more
2016G3: Genes, Genomes, Genetics9 citations Open access
Semantic Scholar
Jdp 2 downregulates Trp 53 transcription to promote leukaemogenesis in the context of Trp 53 heterozygosity
A. C. Rust, R. McIntyre, C. Robles-Espinoza, M. del Castillo Velasco-Herrera +6 more
20124 citations
Semantic Scholar
Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research
J. Alexander, Nicola J. Wyatt, S. Camuzeaux, E. Chekmeneva +22 more
2023Gut2 citations Open access
Semantic Scholar
The mutational profile and clonal landscape of the inflammatory bowel disease affected colon
S. Olafsson, R. McIntyre, T. Coorens, T. Butler +15 more
2019bioRxiv2 citations Open access
Semantic Scholar
Genetic screens in mice for genome integrity maintenance and cancer predisposition.
G. Balmus, R. McIntyre
2014Current Opinion in Genetics and Development2 citations
Semantic Scholar
OP14 Interpreting genome-wide association studies of Inflammatory Bowel Disease through the lens of single-cell sequencing
M. Krzak, L. Taylor, T. Alegbe, M. Ghouraba +10 more
2022Journal of Crohn's & Colitis1 citations
Semantic Scholar
Correction: Mcph1-Deficient Mice Reveal a Role for MCPH1 in Otitis Media
Jing Chen, N. Ingham, S. Clare, C. Raisen +9 more
2013PLoS ONE1 citations Open access
Semantic Scholar
Increased Tumorigenesis Associated with Loss of the Tumor Suppressor Gene Cadm
L. van der Weyden, M. J. Arends, A. Rust, George Poulogiannis +2 more
20121 citations
Semantic Scholar
Transcriptomic effects of rs4845604, an IBD and allergy-associated RORC variant, in stimulated ex vivo CD4+ T cells
Paul A. Wilson, Sara Santos Franco, Liu He, N. Galwey +10 more
2021PLoS ONE0 citations Open access
Semantic Scholar
DOP50 The landscape of somatic mutations in non-neoplastic IBD-affected colon
S. Olafsson, R. McIntyre, T. Coorens, T. Butler +14 more
20200 citations
Semantic Scholar
Peer Review #1 of "Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data (v0.1)"
Alexandre Coudray, A. Battenhouse, Phillip Bucher, V. Iyer +496 more
20180 citations Open access
Semantic Scholar
Explorer Mouse genomic variation and its effect on phenotypes and gene regulation
T. Keane, L. Goodstadt, P. Danecek, Michael A. White +37 more
20170 citations
Semantic Scholar
Genome-wide association of multiple complex traits in outbred mice by ultra low-1 coverage sequencing 2
J. Nicod, R. Davies, Na Cai, C. Hassett +42 more
20160 citations
Semantic Scholar
and lymphocyte differentiation The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis
Aaron Everitt, Lynda Mottram, C. Podrini, M. Lucas +8 more
20140 citations
Semantic Scholar
The critical role of histone H 2 A-deubiquitinase Mysm 1 in hematopoiesis
Ramírez-Solís, Jacqui White, D. Adams, R. Hancock +14 more
20120 citations
Semantic Scholar

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