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A. Nijnik · SciRah

Researcher profile · Semantic Scholar

A. Nijnik

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A. Nijnik — researcher profile on SciRah

h-index: 30
Works: 76
Citations: 5,139

Most-cited papers

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis.
E. Kaufmann, Joaquín Sanz, Jonathan Dunn, N. Khan +16 more
2018Cell1,096 citations
Semantic Scholar
DNA repair is limiting for haematopoietic stem cells during ageing
A. Nijnik, L. Woodbine, C. Marchetti, S. Dawson +12 more
2007Nature543 citations
Semantic Scholar
Modulating immunity as a therapy for bacterial infections
R. Hancock, A. Nijnik, D. Philpott
2012Nature Reviews Microbiology535 citations
Semantic Scholar
The roles of cathelicidin LL-37 in immune defences and novel clinical applications
A. Nijnik, R. Hancock
2009Current opinion in hematology296 citations
Semantic Scholar
M. tuberculosis Reprograms Hematopoietic Stem Cells to Limit Myelopoiesis and Impair Trained Immunity
N. Khan, J. Downey, Joaquín Sanz, E. Kaufmann +12 more
2020Cell252 citations Open access
Semantic Scholar
Synthetic Cationic Peptide IDR-1002 Provides Protection against Bacterial Infections through Chemokine Induction and Enhanced Leukocyte Recruitment
A. Nijnik, Laurence Madera, Shu-Hua Ma, Matthew Waldbrook +7 more
2010Journal of Immunology236 citations Open access
Semantic Scholar
Potential of immunomodulatory host defense peptides as novel anti-infectives
D. Easton, A. Nijnik, M. Mayer, R. Hancock
2009Trends in Biotechnology227 citations Open access
Semantic Scholar
Intracellular Receptor for Human Host Defense Peptide LL-37 in Monocytes1
N. Mookherjee, D. Lippert, P. Hamill, R. Falsafi +8 more
2009Journal of Immunology175 citations Open access
Semantic Scholar
Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections
A. Nijnik, R. Hancock
2009Emerging Health Threats Jour165 citations Open access
Semantic Scholar
Roles and mechanisms of BAP1 deubiquitinase in tumor suppression
Louis Masclef, Oumaima Ahmed, Benjamin Estavoyer, B. Larrivée +3 more
2021Cell Death and Differentiation152 citations Open access
Semantic Scholar
Manipulation of innate immunity by a bacterial secreted peptide: Lantibiotic nisin Z is selectively immunomodulatory
J. Kindrachuk, H. Jenssen, M. Elliott, A. Nijnik +10 more
2013Innate Immunity108 citations Open access
Semantic Scholar
The Role of Sphingosine-1-phosphate Transporter Spns2 in Immune System Function
A. Nijnik, S. Clare, C. Hale, Jing Chen +12 more
2012Journal of Immunology102 citations Open access
Semantic Scholar
The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation.
A. Nijnik, S. Clare, C. Hale, C. Raisen +14 more
2012Blood102 citations Open access
Semantic Scholar
Human Cathelicidin Peptide LL-37 Modulates the Effects of IFN-γ on APCs1
A. Nijnik, J. Pistolic, Aaron W. Wyatt, Sheena Tam +1 more
2009Journal of Immunology99 citations
Semantic Scholar
A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity.
J. Kindrachuk, H. Jenssen, M. Elliott, R. Townsend +6 more
2009Vaccine93 citations
Semantic Scholar
Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss
Jing Chen, N. Ingham, J. Kelly, S. Jadeja +10 more
2014PLoS Genetics66 citations Open access
Semantic Scholar
Signaling Pathways Mediating Chemokine Induction in Keratinocytes by Cathelicidin LL-37 and Flagellin
A. Nijnik, J. Pistolic, N. Filewod, R. Hancock
2012Journal of Innate Immunity61 citations Open access
Semantic Scholar
Repression of p53-target gene Bbc3/PUMA by MYSM1 is essential for the survival of hematopoietic multipotent progenitors and contributes to stem cell maintenance
Jad I. Belle, Jessica C Petrov, D. Langlais, F. Robert +5 more
2016Cell Death and Differentiation55 citations Open access
Semantic Scholar
p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency.
Jad I. Belle, D. Langlais, Jessica C Petrov, M. Pardo +3 more
2015Blood54 citations
Semantic Scholar
H2A-DUBbing the mammalian epigenome: expanding frontiers for histone H2A deubiquitinating enzymes in cell biology and physiology.
Jad I. Belle, A. Nijnik
2014International Journal of Biochemistry and Cell Biology45 citations
Semantic Scholar
Hematopoietic Cell Types: Prototype for a Revised Cell Ontology
A. Diehl, A. Augustine, J. Blake, L. Cowell +12 more
2009Journal of Biomedical Informatics43 citations Open access
Semantic Scholar
Increased Positive Selection of B1 Cells and Reduced B Cell Tolerance to Intracellular Antigens in c1q-Deficient Mice1
H. Ferry, P. Potter, T. Crockford, A. Nijnik +4 more
2007Journal of Immunology41 citations Open access
Semantic Scholar
Ubiquitin Specific Protease 21 Is Dispensable for Normal Development, Hematopoiesis and Lymphocyte Differentiation
Jaspreet Pannu, Jad I. Belle, Michael Förster, C. Duerr +6 more
2015PLoS ONE40 citations Open access
Semantic Scholar
Unbiased immune profiling reveals a natural killer cell-peripheral nerve axis in fibromyalgia
Vivek Verma, Gillian L. Drury, M. Parisien, A. Ö. Özdağ Acarlı +24 more
2021Pain37 citations Open access
Semantic Scholar
BRPF1 is essential for development of fetal hematopoietic stem cells.
Lin-Ya You, Lin Li, Jinfeng Zou, Kezhi Yan +4 more
2016Journal of Clinical Investigation36 citations Open access
Semantic Scholar
B-cell tolerance.
H. Ferry, Janson C. H. Leung, G. Lewis, A. Nijnik +3 more
2006Transplantation36 citations Open access
Semantic Scholar
Deubiquitinase MYSM1 in the Hematopoietic System and beyond: A Current Review
Amanda Fiore, Yue Liang, Y. Lin, Jacky Tung +3 more
2020International Journal of Molecular Sciences33 citations Open access
Semantic Scholar
Cathelicidin Peptide LL-37 Modulates TREM-1 Expression and Inflammatory Responses to Microbial Compounds
G. Amatngalim, A. Nijnik, P. Hiemstra, R. Hancock
2011Inflammation33 citations
Semantic Scholar
Spontaneous B cell hyperactivity in autoimmune-prone MRL mice.
A. Nijnik, H. Ferry, G. Lewis, Eleni Rapsomaniki +5 more
2006International Immunology33 citations
Semantic Scholar
Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome.
A. Nijnik, S. Dawson, T. Crockford, L. Woodbine +7 more
2009Journal of Clinical Investigation31 citations Open access
Semantic Scholar
Comparing the fine specificity of DNA binding by NF-kappaB p50 and p52 using principal coordinates analysis.
A. Nijnik, R. Mott, D. Kwiatkowski, I. Udalova
2003Nucleic Acids Research26 citations Open access
Semantic Scholar
Immunomodulatory approaches for prevention and treatment of infectious diseases.
A. Nijnik
2013Current Opinion in Microbiology25 citations
Semantic Scholar
Deubiquitinase MYSM1 Is Essential for Normal Fetal Liver Hematopoiesis and for the Maintenance of Hematopoietic Stem Cells in Adult Bone Marrow
Michael Förster, Jad I. Belle, Jessica C Petrov, E. Ryder +2 more
2015Stem Cells and Development24 citations
Semantic Scholar
A Loss-of-Function Mutation in the Integrin Alpha L (Itgal) Gene Contributes to Susceptibility to Salmonella enterica Serovar Typhimurium Infection in Collaborative Cross Strain CC042
Jing Zhang, Megan R. Teh, J. Kim, Megan M. Eva +6 more
2019Infection and Immunity23 citations Open access
Semantic Scholar
Hematologic dysfunction in cancer: Mechanisms, effects on antitumor immunity, and roles in disease progression
Viktoria Plackoska, Dania Shaban, A. Nijnik
2022Frontiers in Immunology22 citations Open access
Semantic Scholar
MYSM1 maintains ribosomal protein gene expression in hematopoietic stem cells to prevent hematopoietic dysfunction.
Jad I. Belle, HanChen Wang, Amanda Fiore, Jessica C Petrov +11 more
2020JCI Insight21 citations Open access
Semantic Scholar
An investigation of transmission ratio distortion in the central region of the human MHC
N. Hanchard, K. Rockett, I. Udalova, J. Wilson +6 more
2006Genes and Immunity20 citations
Semantic Scholar
p53-dependent induction of P2X7 on hematopoietic stem and progenitor cells regulates hematopoietic response to genotoxic stress
Lin-Tze Tung, HanChen Wang, Jad I. Belle, Jessica C Petrov +2 more
2021Cell Death and Disease19 citations Open access
Semantic Scholar
Regulation of B Lymphocyte Development by Histone H2A Deubiquitinase BAP1
Y. Lin, Yue Liang, HanChen Wang, Lin-Tze Tung +6 more
2021Frontiers in Immunology17 citations Open access
Semantic Scholar
Glutathione Metabolism Is a Regulator of the Acute Inflammatory Response of Monocytes to (1→3)-β-D-Glucan
R. Ramendra, Mathieu Mancini, Jose-Mauricio Ayala, Lin-Tze Tung +5 more
2021Frontiers in Immunology16 citations Open access
Semantic Scholar
Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III
N. Hanchard, M. Diakité, O. Koch, B. Keating +8 more
2006Immunogenetics14 citations
Semantic Scholar
A role for the histone H2A deubiquitinase MYSM1 in maintenance of CD8+ T cells
Michael Förster, Rupinder K Boora, Jessica C Petrov, Nassima Fodil +4 more
2017Immunology13 citations Open access
Semantic Scholar
MYSM1‐dependent checkpoints in B cell lineage differentiation and B cell–mediated immune response
Michael Förster, Kyo Farrington, Jessica C Petrov, Jad I. Belle +5 more
2017Journal of Leukocyte Biology11 citations
Semantic Scholar
Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma
Y. Lin, HanChen Wang, Amanda Fiore, Michael Förster +6 more
2021Journal of Cellular and Molecular Medicine9 citations Open access
Semantic Scholar
USP44 is dispensable for normal hematopoietic stem cell function, lymphocyte development, and B-cell-mediated immune response in a mouse model.
Y. Lin, M. Forster, Yue Liang, Mansen Yu +6 more
2019Experimental Hematology9 citations Open access
Semantic Scholar
Engineering tough blood clots for rapid haemostasis and enhanced regeneration
Shuai-Bing Jiang, Guang-Yu Bao, Zhen Yang, Jing Wu +12 more
2026Nature8 citations Open access
Semantic Scholar
Mysm1 expression in the bone marrow niche is not essential for hematopoietic maintenance.
Jessica C Petrov, A. Nijnik
2017Experimental Hematology8 citations Open access
Semantic Scholar
Host Defense Peptides: Bridging Antimicrobial and Immunomodulatory Activities
J. Kindrachuk, A. Nijnik, R. Hancock
20108 citations
Semantic Scholar
Dysregulation of B lymphocyte development in the SKG mouse model of rheumatoid arthritis
Joo Eun June Kim, Lin-Tze Tung, Roselyn Jiang, Mitra Yousefi +4 more
2023Immunology6 citations Open access
Semantic Scholar
Histone H2A deubiquitinases in the transcriptional programs of development and hematopoiesis: a consolidated analysis.
HanChen Wang, D. Langlais, A. Nijnik
2023International Journal of Biochemistry and Cell Biology6 citations
Semantic Scholar

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R. Hancock×13
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R. Hancock — researcher profile on SciRah
Jad I. Belle×11
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D. Langlais×10
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Jessica C Petrov×8
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HanChen Wang — researcher profile on SciRah

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