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S. Pierno · SciRah

Researcher profile · Semantic Scholar

S. Pierno

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S. Pierno — researcher profile on SciRah

h-index: 38
Works: 139
Citations: 3,899

Most-cited papers

Taurine: the appeal of a safe amino acid for skeletal muscle disorders
A. De Luca, S. Pierno, D. Camerino
2015Journal of Translational Medicine242 citations Open access
Semantic Scholar
Enhanced Dystrophic Progression in mdx Mice by Exercise and Beneficial Effects of Taurine and Insulin-Like Growth Factor-1
A. De Luca, S. Pierno, A. Liantonio, Michela Cetrone +6 more
2003Journal of Pharmacology and Experimental Therapeutics219 citations
Semantic Scholar
Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery
P. Imbrici, A. Liantonio, G. Camerino, M. De Bellis +8 more
2016Frontiers in Pharmacology146 citations Open access
Semantic Scholar
Redox homeostasis, oxidative stress and disuse muscle atrophy
M. Pellegrino, J. Desaphy, L. Brocca, S. Pierno +2 more
2011Journal of Physiology143 citations Open access
Semantic Scholar
A multidisciplinary evaluation of the effectiveness of cyclosporine a in dystrophic mdx mice.
A. De Luca, B. Nico, A. Liantonio, M. Didonna +16 more
2005American Journal of Pathology135 citations Open access
Semantic Scholar
Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb‐unloaded mice
L. Brocca, M. Pellegrino, J. Desaphy, S. Pierno +2 more
2010Experimental Physiology81 citations Open access
Semantic Scholar
Fluvastatin and Atorvastatin Affect Calcium Homeostasis of Rat Skeletal Muscle Fibers in Vivo and in Vitro by Impairing the Sarcoplasmic Reticulum/Mitochondria Ca2+-Release System
A. Liantonio, V. Giannuzzi, V. Cippone, G. Camerino +2 more
2007Journal of Pharmacology and Experimental Therapeutics81 citations Open access
Semantic Scholar
The alteration of calcium homeostasis in adult dystrophic mdx muscle fibers is worsened by a chronic exercise in vivo.
B. Fraysse, A. Liantonio, Michela Cetrone, R. Burdi +5 more
2004Neurobiology of Disease81 citations Open access
Semantic Scholar
Taurine and Skeletal Muscle Disorders
D. Camerino, D. Tricarico, S. Pierno, J. Desaphy +6 more
2004Neurochemical Research77 citations
Semantic Scholar
Decrease in resting calcium and calcium entry associated with slow‐to‐fast transition in unloaded rat soleus muscle
B. Fraysse, J. Desaphy, S. Pierno, A. De Luca +3 more
2003The FASEB Journal77 citations
Semantic Scholar
Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse.
S. Pierno, J. Desaphy, A. Liantonio, M. De Bellis +8 more
2002Brain : a journal of neurology77 citations
Semantic Scholar
Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles.
J. Desaphy, S. Pierno, A. Liantonio, V. Giannuzzi +8 more
2010Pharmacological Research75 citations Open access
Semantic Scholar
Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile.
J. Desaphy, S. Pierno, A. Liantonio, A. De Luca +7 more
2005Neurobiology of Disease74 citations Open access
Semantic Scholar
Skeletal muscle disuse induces fibre type-dependent enhancement of Na(+) channel expression.
J. Desaphy, S. Pierno, C. Léoty, A. L. George +2 more
2001Brain : a journal of neurology74 citations Open access
Semantic Scholar
Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin‐induced cachexia
E. Conte, G. Camerino, A. Mele, M. De Bellis +18 more
2017Journal of Cachexia, Sarcopenia and Muscle69 citations Open access
Semantic Scholar
Role of tumour necrosis factor α, but not of cyclo‐oxygenase‐2‐derived eicosanoids, on functional and morphological indices of dystrophic progression in mdx mice: a pharmacological approach
S. Pierno, B. Nico, R. Burdi, A. Liantonio +11 more
2007Neuropathology and Applied Neurobiology69 citations
Semantic Scholar
Effects of chronic treatment with statins and fenofibrate on rat skeletal muscle: a biochemical, histological and electrophysiological study
S. Pierno, M. Didonna, V. Cippone, A. De Luca +10 more
2006British Journal of Pharmacology61 citations Open access
Semantic Scholar
Alteration of excitation‐contraction coupling mechanism in extensor digitorum longus muscle fibres of dystrophic mdx mouse and potential efficacy of taurine
A. De Luca, S. Pierno, A. Liantonio, Michela Cetrone +4 more
2001British Journal of Pharmacology60 citations Open access
Semantic Scholar
Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance
S. Pierno, J. Desaphy, A. Liantonio, A. De Luca +5 more
2007Journal of Physiology59 citations Open access
Semantic Scholar
Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone.
B. Fraysse, J. Desaphy, Jean-François Rolland, S. Pierno +7 more
2006Neurobiology of Disease59 citations Open access
Semantic Scholar
Therapeutic approaches to ion channel diseases.
D. Camerino, J. Desaphy, D. Tricarico, S. Pierno +1 more
2008Advances in Genetics58 citations
Semantic Scholar
Statins and fenofibrate affect skeletal muscle chloride conductance in rats by differently impairing ClC‐1 channel regulation and expression
S. Pierno, G. Camerino, V. Cippone, Jean-François Rolland +7 more
2009British Journal of Pharmacology52 citations Open access
Semantic Scholar
Cardiovascular, neurological, and pulmonary events following vaccination with the BNT162b2, ChAdOx1 nCoV-19, and Ad26.COV2.S vaccines: An analysis of European data
L. Cari, Mahdieh Naghavi Alhosseini, P. Fiore, S. Pierno +4 more
2021Journal of Autoimmunity50 citations Open access
Semantic Scholar
Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.
A. Liantonio, M. Pusch, A. Picollo, P. Guida +6 more
2004Journal of the American Society of Nephrology49 citations Open access
Semantic Scholar
Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy
R. Capogrosso, P. Mantuano, K. Uaesoontrachoon, A. Cozzoli +14 more
2017The FASEB Journal48 citations Open access
Semantic Scholar
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function.
G. Fracchiolla, A. Laghezza, L. Piemontese, P. Tortorella +8 more
2009Journal of Medicinal Chemistry47 citations Open access
Semantic Scholar
Muscle loading modulates aquaporin‐4 expression in skeletal muscle
A. Frigeri, G. P. Nicchia, J. Desaphy, S. Pierno +3 more
2001The FASEB Journal47 citations
Semantic Scholar
Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin‐specific receptor
S. Pierno, A. De Luca, J. Desaphy, B. Fraysse +6 more
2003British Journal of Pharmacology44 citations Open access
Semantic Scholar
Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.
A. Liantonio, A. Accardi, G. Carbonara, G. Fracchiolla +8 more
2002Molecular Pharmacology44 citations
Semantic Scholar
Different ability of clenbuterol and salbutamol to block sodium channels predicts their therapeutic use in muscle excitability disorders.
J. Desaphy, S. Pierno, A. De Luca, P. Di Donna +1 more
2003Molecular Pharmacology42 citations
Semantic Scholar
Potential benefits of taurine in the prevention of skeletal muscle impairment induced by disuse in the hindlimb-unloaded rat
S. Pierno, A. Liantonio, G. Camerino, M. De Bellis +9 more
2011Amino Acids41 citations
Semantic Scholar
A long‐term treatment with taurine prevents cardiac dysfunction in mdx mice
A. Mele, P. Mantuano, M. De Bellis, Francesco Rana +10 more
2019Translational Research: The Journal of Laboratory and Clinical Medicine40 citations Open access
Semantic Scholar
Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase.
A. Cozzoli, A. Liantonio, E. Conte, M. Cannone +8 more
2014American Journal of Physiology - Cell Physiology38 citations Open access
Semantic Scholar
An olive oil-derived antioxidant mixture ameliorates the age-related decline of skeletal muscle function
S. Pierno, D. Tricarico, A. Liantonio, A. Mele +9 more
2014AGE38 citations Open access
Semantic Scholar
Statin or fibrate chronic treatment modifies the proteomic profile of rat skeletal muscle.
G. Camerino, M. Pellegrino, L. Brocca, C. Digennaro +3 more
2011Biochemical Pharmacology36 citations Open access
Semantic Scholar
Statin-Induced Myopathy: Translational Studies from Preclinical to Clinical Evidence
G. Camerino, N. Tarantino, I. Canfora, M. De Bellis +2 more
2021International Journal of Molecular Sciences34 citations Open access
Semantic Scholar
Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options
G. Camerino, A. Fonzino, E. Conte, M. De Bellis +9 more
2019Scientific Reports33 citations Open access
Semantic Scholar
Effects of Pleiotrophin Overexpression on Mouse Skeletal Muscles in Normal Loading and in Actual and Simulated Microgravity
G. Camerino, S. Pierno, A. Liantonio, M. De Bellis +16 more
2013PLoS ONE31 citations Open access
Semantic Scholar
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity
M. De Bellis, R. Carbonara, J. Roussel, A. Farinato +9 more
2017Neuropharmacology30 citations Open access
Semantic Scholar
Risk of Myopathy in Patients in Therapy with Statins: Identification of Biological Markers in a Pilot Study
G. Camerino, O. Musumeci, E. Conte, K. Musaraj +11 more
2017Frontiers in Pharmacology30 citations Open access
Semantic Scholar
Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin.
G. Camerino, M. De Bellis, E. Conte, A. Liantonio +12 more
2016Toxicology and Applied Pharmacology30 citations Open access
Semantic Scholar
New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse.
A. De Luca, S. Pierno, A. Liantonio, J. Desaphy +9 more
2004Neuromuscular Disorders30 citations
Semantic Scholar
BCAAs and Di-Alanine supplementation in the prevention of skeletal muscle atrophy: preclinical evaluation in a murine model of hind limb unloading.
P. Mantuano, Brigida Boccanegra, Gianluca Bianchini, E. Conte +8 more
2021Pharmacological Research28 citations Open access
Semantic Scholar
On the Metabolically Active Form of Metaglidasen: Improved Synthesis and Investigation of Its Peculiar Activity on Peroxisome Proliferator‐Activated Receptors and Skeletal Muscles
A. Laghezza, R. Montanari, A. Lavecchia, L. Piemontese +10 more
2015ChemMedChem27 citations Open access
Semantic Scholar
Paracrine Effects of IGF-1 Overexpression on the Functional Decline Due to Skeletal Muscle Disuse: Molecular and Functional Evaluation in Hindlimb Unloaded MLC/mIgf-1 Transgenic Mice
S. Pierno, G. Camerino, M. Cannone, A. Liantonio +12 more
2013PLoS ONE24 citations Open access
Semantic Scholar
Hypertriglyceridemia Therapy: Past, Present and Future Perspectives
I. Canfora, S. Pierno
2024International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation
G. Camerino, J. Desaphy, M. De Bellis, R. Capogrosso +12 more
2015PLoS ONE23 citations Open access
Semantic Scholar
Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness.
A. De Luca, S. Pierno, A. Liantonio, Diana Conte-Camerino
2002Neuromuscular Disorders23 citations
Semantic Scholar
Structural requisites of 2‐(p‐chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC‐1
A. Liantonio, A. De Luca, S. Pierno, M. Didonna +10 more
2003British Journal of Pharmacology22 citations Open access
Semantic Scholar
Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo.
J. Desaphy, A. Farinato, C. Altamura, M. De Bellis +11 more
2020Experimental Neurology19 citations
Semantic Scholar

Frequent co-authors

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A. De Luca×36
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A. De Luca — researcher profile on SciRah
A. Liantonio×33
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A. Liantonio — researcher profile on SciRah
J. Desaphy×27
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J. Desaphy — researcher profile on SciRah
D. Camerino×26
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D. Camerino — researcher profile on SciRah

×18

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G. Camerino — researcher profile on SciRah

M. De Bellis×16

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M. De Bellis — researcher profile on SciRah

C. Camerino×11

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C. Camerino — researcher profile on SciRah

Diana Conte-Camerino×10

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Diana Conte-Camerino — researcher profile on SciRah

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E. Conte — researcher profile on SciRah

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B. Fraysse — researcher profile on SciRah

D. Tricarico×8

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D. Tricarico — researcher profile on SciRah

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M. Didonna — researcher profile on SciRah