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P. Nelson · SciRah

Researcher profile · Semantic Scholar

P. Nelson

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P. Nelson — researcher profile on SciRah

h-index: 103
Works: 456
Citations: 60K

Most-cited papers

Genomic correlates of clinical outcome in advanced prostate cancer
W. Abida, J. Cyrta, G. Heller, D. Prandi +39 more
2019Proceedings of the National Academy of Sciences of the United States of America1,265 citations Open access
Semantic Scholar
The long tail of oncogenic drivers in prostate cancer
J. Armenia, Stephanie A. M. Wankowicz, David Liu, Jian-Jiong Gao +35 more
2018Nature Genetics779 citations Open access
Semantic Scholar
Inactivation of CDK12 delineates a distinct immunogenic class of advanced prostate cancer
Yi-Mi Wu, M. Cieslik, Robert J. Lonigro, P. Vats +16 more
2018Cell547 citations Open access
Semantic Scholar
Genomic and phenotypic heterogeneity in prostate cancer
Michael C. Haffner, W. Zwart, M. Roudier, L. True +5 more
2020Nature reviews. Urology457 citations Open access
Semantic Scholar
TMPRSS2 and COVID-19: Serendipity or opportunity for intervention?
Konrad H. Stopsack, L. Mucci, E. Antonarakis, P. Nelson +1 more
2020Cancer Discovery354 citations Open access
Semantic Scholar
The role of lineage plasticity in prostate cancer therapy resistance
H. Beltran, Andrew Hruszkewycz, H. Scher, Jeffrey Hildesheim +28 more
2019Clinical Cancer Research345 citations Open access
Semantic Scholar
Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer.
M. Labrecque, I. Coleman, Lisha G. Brown, L. True +18 more
2019Journal of Clinical Investigation342 citations Open access
Semantic Scholar
Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer
A. Sharp, I. Coleman, W. Yuan, Cynthia Sprenger +18 more
2018Journal of Clinical Investigation341 citations Open access
Semantic Scholar
Structural alterations driving castration-resistant prostate cancer revealed by linked-read genome sequencing
S. Viswanathan, G. Ha, A. Hoff, J. Wala +26 more
2018Cell314 citations Open access
Semantic Scholar
Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress
Michael D Nyquist, Alexandra Corella, I. Coleman, N. De Sarkar +13 more
2020Cell Reports246 citations Open access
Semantic Scholar
Targeting the perivascular niche sensitizes disseminated tumour cells to chemotherapy
P. Carlson, A. Dasgupta, C. A. Grzelak, Jeanna Kim +12 more
2019Nature Cell Biology234 citations Open access
Semantic Scholar
Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling
L. Brady, M. Kriner, I. Coleman, C. Morrissey +11 more
2021Nature Communications209 citations Open access
Semantic Scholar
ONECUT2 is a Targetable Master Regulator of Lethal Prostate Cancer that Suppresses the Androgen Axis
Mirja Rotinen, S. You, Julie Yang, Simon G. Coetzee +18 more
2018Nature Medicine177 citations Open access
Semantic Scholar
Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging.
Denise P. Muñoz, S. Yannone, A. Daemen, Yu Sun +11 more
2019JCI Insight156 citations Open access
Semantic Scholar
ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer
Laura Cato, Jonas de Tribolet-Hardy, Irene Lee, Jaice T. Rottenberg +31 more
2019Cancer Cell151 citations Open access
Semantic Scholar
Association of Clonal Hematopoiesis in DNA Repair Genes With Prostate Cancer Plasma Cell-free DNA Testing Interference
K. Jensen, E. Konnick, M. Schweizer, Alexandra O. Sokolova +8 more
2020JAMA Oncology150 citations Open access
Semantic Scholar
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer
Sylvan C. Baca, D. Takeda, Ji-Heui Seo, Justin H. Hwang +37 more
2020Nature Communications139 citations Open access
Semantic Scholar
Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer
P. Cejas, Ying-Tian Xie, Alba Font-Tello, Klothilda Lim +34 more
2020Nature Communications137 citations Open access
Semantic Scholar
Activation of MAPK signaling by CXCR7 leads to enzalutamide resistance in prostate cancer
Shang-Ze Li, K. Fong, G. Gritsina, Ali Zhang +13 more
2019Cancer Research107 citations Open access
Semantic Scholar
Microsatellite instability in prostate cancer by PCR or next-generation sequencing
J. Hempelmann, Christina M. Lockwood, E. Konnick, M. Schweizer +7 more
2018Journal of Immunotherapy for Cancer106 citations Open access
Semantic Scholar
Mismatch repair deficiency in metastatic prostate cancer: Response to PD-1 blockade and standard therapies
L. Graham, B. Montgomery, Heather H. Cheng, Evan Y. Yu +5 more
2020PLoS ONE96 citations Open access
Semantic Scholar
Supraphysiological androgens suppress prostate cancer growth through androgen receptor-mediated DNA damage.
P. Chatterjee, M. Schweizer, Jared M. Lucas, I. Coleman +11 more
2019Journal of Clinical Investigation93 citations Open access
Semantic Scholar
Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene Mutations
M. Schweizer, E. Antonarakis, T. Bismar, Liana B. Guedes +14 more
2019JCO Precision Oncology93 citations Open access
Semantic Scholar
Role of androgen receptor splice variant 7 (AR-V7) in prostate cancer resistance to 2nd generation androgen receptor signaling inhibitors
Yezi Zhu, Susan L. Dalrymple, I. Coleman, S. Zheng +11 more
2020Oncogene92 citations Open access
Semantic Scholar
17-Gene Genomic Prostate Score Test Results in the Canary Prostate Active Surveillance Study (PASS) Cohort.
D. Lin, Ying-Ye Zheng, Jesse K. McKenney, Marshall D. Brown +17 more
2020Journal of Clinical Oncology82 citations Open access
Semantic Scholar
EZH2 cooperates with gain‐of‐function p53 mutants to promote cancer growth and metastasis
Yu Zhao, L. Ding, De-Jie Wang, Zhen-Qing Ye +16 more
2019EMBO Journal77 citations Open access
Semantic Scholar
Concordance of DNA Repair Gene Mutations in Paired Primary Prostate Cancer Samples and Metastatic Tissue or Cell-Free DNA.
M. Schweizer, S. Sivakumar, H. Tukachinsky, I. Coleman +6 more
2021JAMA Oncology74 citations Open access
Semantic Scholar
A MYC and RAS co-activation signature in localized prostate cancer drives bone metastasis and castration resistance
J. Arriaga, S. Panja, M. Alshalalfa, Junfei Zhao +22 more
2020Nature Cancer71 citations Open access
Semantic Scholar
Neoadjuvant-intensive androgen deprivation therapy selects for prostate tumor foci with diverse subclonal oncogenic alterations
A. Sowalsky, Huihui Ye, M. Bhasin, E. V. Van Allen +15 more
2018Cancer Research69 citations Open access
Semantic Scholar
Regulation of CEACAM5 and therapeutic efficacy of an anti-CEACAM5-SN38 antibody-drug conjugate in neuroendocrine prostate cancer
D. DeLucia, T. Cardillo, Lisa S. Ang, M. Labrecque +12 more
2020Clinical Cancer Research68 citations Open access
Semantic Scholar
Tailoring Intensity of Active Surveillance for Low-Risk Prostate Cancer Based on Individualized Prediction of Risk Stability.
M. Cooperberg, Ying-Ye Zheng, A. Faino, Lisa F. Newcomb +12 more
2020JAMA Oncology66 citations Open access
Semantic Scholar
The androgen receptor regulates a druggable translational regulon in advanced prostate cancer
Yuzhen Liu, Jessie L. Horn, Kalyan Banda, Asha Z. Goodman +20 more
2019Science Translational Medicine65 citations Open access
Semantic Scholar
Contribution of Adrenal Glands to Intra-tumor Androgens and Growth of Castration Resistant Prostate Cancer.
E. Mostaghel, Ai-Lin Zhang, Susana A. Hernandez, Brett T. Mark +15 more
2018Clinical Cancer Research62 citations Open access
Semantic Scholar
Upregulation of scavenger receptor B1 is required for steroidogenic and non-steroidogenic cholesterol metabolism in prostate cancer
Jacob A. Gordon, Jake W. Noble, A. Midha, F. Derakhshan +10 more
2019Cancer Research60 citations Open access
Semantic Scholar
BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program
Dae-Hwan Kim, Duan-Chen Sun, W. Storck, Katherine Welker Leng +32 more
2021Clinical Cancer Research58 citations Open access
Semantic Scholar
Refined Analysis of Prostate-specific Antigen Kinetics to Predict Prostate Cancer Active Surveillance Outcomes
M. Cooperberg, J. Brooks, A. Faino, Lisa F. Newcomb +12 more
2018European Urology57 citations Open access
Semantic Scholar
Resistance to androgen receptor signaling inhibition does not necessitate development of neuroendocrine prostate cancer
W. Brennen, Yezi Zhu, I. Coleman, Susan L. Dalrymple +17 more
2021JCI Insight56 citations Open access
Semantic Scholar
Multiplexed functional genomic analysis of 5’ untranslated region mutations across the spectrum of prostate cancer
Yiting Lim, Sonali Arora, Samantha L. Schuster, L. Corey +10 more
2021Nature Communications56 citations Open access
Semantic Scholar
Imaging Fibroblast Activation Protein Alpha improves diagnosis of metastatic Prostate Cancer with Positron Emission Tomography
Hallie M. Hintz, Joseph P. Gallant, D. V. Vander Griend, I. Coleman +2 more
2020Clinical Cancer Research53 citations Open access
Semantic Scholar
MAPK4 promotes prostate cancer by concerted activation of androgen receptor and AKT.
Tao Shen, Wei Wang, Wolong Zhou, I. Coleman +10 more
2021Journal of Clinical Investigation51 citations Open access
Semantic Scholar
Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts
Hung-Ming Lam, Holly M. Nguyen, M. Labrecque, Lisha G. Brown +11 more
2019European Urology51 citations Open access
Semantic Scholar
Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer
Joshua W. Russo, Ce Gao, Swati S. Bhasin, O. Voznesensky +10 more
2018Cancer Research50 citations Open access
Semantic Scholar
Dickkopf-1 Can Lead to Immune Evasion in Metastatic Castration-Resistant Prostate Cancer.
D. Wise, J. A. Schneider, J. Armenia, V. A. Febles +24 more
2020JCO Precision Oncology47 citations Open access
Semantic Scholar
Targeting RET Kinase in Neuroendocrine Prostate Cancer
Halena R. VanDeusen, Johnny R. Ramroop, K. Morel, S. Y. Bae +18 more
2020Molecular Cancer Research44 citations Open access
Semantic Scholar
Genomic distinctions between metastatic lower and upper tract urothelial carcinoma revealed through rapid autopsy.
B. Winters, N. De Sarkar, Sonali Arora, H. Bolouri +16 more
2019JCI Insight44 citations Open access
Semantic Scholar
The Aged Microenvironment Influences the Tumorigenic Potential of Malignant Prostate Epithelial Cells
D. Bianchi-Frias, M. Damodarasamy, Susana A. Hernandez, R. M. Gil da Costa +4 more
2018Molecular Cancer Research44 citations Open access
Semantic Scholar
Identification of Therapeutic Vulnerabilities in Small Cell Neuroendocrine Prostate Cancer
Alexandra Corella, Ma Victoria Andrea Cabiliza Ordonio, I. Coleman, Jared M. Lucas +12 more
2019Clinical Cancer Research42 citations Open access
Semantic Scholar
The Heterogeneity of Prostate Cancers Lacking AR Activity Will Require Diverse Treatment Approaches
M. Labrecque, J. Alumkal, I. Coleman, P. Nelson +1 more
2021Endocrine-Related Cancer40 citations Open access
Semantic Scholar
Polyclonal BRCA2 Reversion Mutations Detected in Circulating Tumor DNA After Platinum Chemotherapy in a Patient With Metastatic Prostate Cancer.
Heather H. Cheng, S. Salipante, P. Nelson, B. Montgomery +1 more
2018JCO Precision Oncology39 citations Open access
Semantic Scholar
A Novel Flavonoid Composition Targets Androgen Receptor Signaling and Inhibits Prostate Cancer Growth in Preclinical Models12
K. Mamouni, Shumin Zhang, Xin Li, Yanhua Chen +7 more
2018Neoplasia38 citations Open access
Semantic Scholar

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