Annette Sievers

Most-cited papers

1. The ribosome as an entropy trap.

   Annette Sievers, Malte Beringer, M. Rodnina, R. Wolfenden

   2004Proceedings of the National Academy of Sciences of the United States of America351 citations Open access

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2. Transient CHO expression platform for robust antibody production and its enhanced N‐glycan sialylation on therapeutic glycoproteins

   Xiao-Tian Zhong, Wei-Jun Ma, Caryl L Meade, A. Tam +20 more

   2018Biotechnology progress (Print)44 citations

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3. Equilibrium of formation of the 6-carbanion of UMP, a potential intermediate in the action of OMP decarboxylase.

   Annette Sievers, R. Wolfenden

   2002Journal of the American Chemical Society42 citations

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4. Carbon isotope effect study on orotidine 5'-monophosphate decarboxylase: support for an anionic intermediate.

   Jeremy Van Vleet, L. Reinhardt, Brian G. Miller, Annette Sievers +1 more

   2008Biochemistry35 citations

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5. Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing

   Yan Weng, T. Ishino, Annette Sievers, Saswata Talukdar +22 more

   2018Scientific Reports31 citations Open access

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6. Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease

   Xiao-Tian Zhong, S. Jagarlapudi, Yan Weng, Mellisa Ly +27 more

   2020Journal of Biological Chemistry28 citations Open access

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7. The effective molarity of the substrate phosphoryl group in the transition state for yeast OMP decarboxylase.

   Annette Sievers, R. Wolfenden

   2005Bioorganic chemistry (Print)27 citations

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8. Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation

   E. Fung, Liya Kang, Diana Sapashnik, Susan Benard +18 more

   2021Scientific Reports22 citations Open access

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9. Novel synthesis and structural characterization of a high-affinity paramagnetic kinase probe for the identification of non-ATP site binders by nuclear magnetic resonance.

   F. Moy, Arthur Lee, L. K. Gavrin, Zhang-Bao Xu +6 more

   2010Journal of Medicinal Chemistry21 citations Open access

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10. Development of a long acting human growth hormone analog suitable for once a week dosing.

    M. Palanki, A. Bhat, Ben Bolanos, F. Brunel +9 more

    2013Bioorganic & Medicinal Chemistry Letters16 citations

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11. Genetic rearrangement during site specific integration event facilitates cell line development of a bispecific molecule

    Barbara Tevelev, H. Patel, K. Shields, Wei Wei +17 more

    2021Biotechnology progress (Print)14 citations Open access

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12. Exploring a role for flow-induced aggregation assays in platform formulation optimisation for antibody-based proteins.

    Leon F. Willis, Vishal M. Toprani, S. Wijetunge, Annette Sievers +6 more

    2023Journal of Pharmacy and Science6 citations Open access

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13. Erratum: The ribosome as an entropy trap (Proceedings of the National Academy of Sciences of the United States of America (May 25, 2004) 101, 21 (7897-7901))

    Annette Sievers, Malte Beringer, M. Rodnina, R. Wolfenden

    20042 citations

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14. In Vitro and In Vivo Potency Differences between AAVRh74var and AAV5 Vectors Encoding the Same High-Activity Human Factor IX Variant, FIX-R338L, Expression Cassette: Implications for Hemophilia B Gene Therapy

    Debra D Pittman, S. Rakhe, Lisa J Wilcox, D. Leblanc +4 more

    2024Blood0 citations

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