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E. Whalley · SciRah

Researcher profile · Semantic Scholar

E. Whalley

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E. Whalley — researcher profile on SciRah

h-index: 21
Works: 92
Citations: 1,432

Most-cited papers

Improved pharmacokinetic properties of a polyethylene glycol-modified form of interferon-beta-1a with preserved in vitro bioactivity.
R. Pepinsky, D. Lepage, A. Gill, A. Chakraborty +6 more
2001Journal of Pharmacology and Experimental Therapeutics136 citations
Semantic Scholar
Inhibition of α4 Integrin Protects Against Transient Focal Cerebral Ischemia in Normotensive and Hypertensive Rats
Jane K. Relton, K. Sloan, E. Frew, E. Whalley +2 more
200199 citations Open access
Semantic Scholar
CP-0597, a selective bradykinin B2 receptor antagonist, inhibits brain injury in a rat model of reversible middle cerebral artery occlusion.
J. Relton, V. Beckey, W. L. Hanson, E. Whalley
1997Stroke95 citations
Semantic Scholar
Differential effects of treatment with a small-molecule VLA-4 antagonist before and after onset of relapsing EAE.
B. Theien, C. Vanderlugt, C. Nickerson-Nutter, M. Cornebise +4 more
2003Blood73 citations Open access
Semantic Scholar
Vasomotor and permeability effects of bradykinin in the cerebral microcirculation.
M. Wahl, E. Whalley, A. Unterberg, L. Schilling +3 more
1996Immunopharmacology69 citations
Semantic Scholar
The Role of Bradykinin B1 and B2 Receptors for Secondary Brain Damage after Traumatic Brain Injury in Mice
Raimund Trabold, C. Erös, K. Zweckberger, J. Relton +6 more
2010Journal of Cerebral Blood Flow and Metabolism65 citations Open access
Semantic Scholar
Novel bicyclic piperazine derivatives of triazolotriazine and triazolopyrimidines as highly potent and selective adenosine A2A receptor antagonists.
Hai-Ruo Peng, G. Kumaravel, Gang Yao, Li Sha +10 more
2004Journal of Medicinal Chemistry61 citations Open access
Semantic Scholar
An Assessment of the Mechanistic Differences Between Two Integrin α4β1 Inhibitors, the Monoclonal Antibody TA-2 and the Small Molecule BIO5192, in Rat Experimental Autoimmune Encephalomyelitis
D. Leone, K. Giza, A. Gill, B. M. Dolinski +15 more
2003Journal of Pharmacology and Experimental Therapeutics60 citations
Semantic Scholar
Synthesis of alkyne derivatives of a novel triazolopyrazine as A(2A) adenosine receptor antagonists.
Gang Yao, Serajul Haque, Li Sha, G. Kumaravel +7 more
2005Bioorganic & Medicinal Chemistry Letters51 citations Open access
Semantic Scholar
CP-0127, a novel potent bradykinin antagonist, increases survival in rat and rabbit models of endotoxin shock.
E. Whalley, J. A. Solomon, D. M. Modafferi, K. A. Bonham +1 more
1992Agents and actions. Supplements46 citations
Semantic Scholar
Inhibition of alpha4 integrin protects against transient focal cerebral ischemia in normotensive and hypertensive rats.
J. Relton, K. Sloan, E. Frew, E. Whalley +2 more
2001Stroke43 citations
Semantic Scholar
Comparison of Three Different A1 Adenosine Receptor Antagonists on Infarct Size and Multiple Cycle Ischemic Preconditioning in Anesthetized Dogs
J. Auchampach, Xiaowei Jin, Jeannine M. Moore, Tina C. Wan +8 more
2004Journal of Pharmacology and Experimental Therapeutics42 citations
Semantic Scholar
The effect of kinin agonists and antagonists on the pain response of the human blister base
E. Whalley, S. Clegg, John M. Stewart, R. Vavrek
1987Naunyn-Schmiedeberg's Archives of Pharmacology42 citations
Semantic Scholar
Bradykinin receptor antagonists type 2 attenuate the inflammatory changes in peptidoglycan-induced acute arthritis in the Lewis rat
A. Uknis, R. D. de la Cadena, R. Janardham, R. Sartor +2 more
2001Inflammation Research41 citations
Semantic Scholar
Discovery and therapeutic potential of kinin receptor antagonists
E. Whalley, C. Figueroa, L. Gera, K. Bhoola
2012Expert Opinion on Drug Discovery39 citations
Semantic Scholar
Vascular smooth muscle response to fibrinogen degradation products and 5-hydroxytryptamine: possible role in cerebral vasospasm in man.
C. Forster, E. Whalley, J. Mohan, John Dutton
1980British Journal of Clinical Pharmacology26 citations Open access
Semantic Scholar
Protective Effect of Tonapofylline (BG9928), an Adenosine A1 Receptor Antagonist, against Cisplatin-Induced Acute Kidney Injury in Rats
A. Gill, K. Wortham, D. Costa, W. Davis +2 more
2009American Journal of Nephrology25 citations
Semantic Scholar
Angiotensin‐Converting Enzyme, Bradykinin, Angiotensin, and Cerebral Vessel Reactivity
E. Whalley, M. Wahl, C. A. Sampaio
1983HYPERTENSION24 citations Open access
Semantic Scholar
Design, Synthesis, and Analysis of a Polyethelene Glycol-Modified (PEGylated) Small Molecule Inhibitor of Integrin α4β1 with Improved Pharmaceutical Properties
R. Pepinsky, W.-C. Lee, M. Cornebise, A. Gill +14 more
2005Journal of Pharmacology and Experimental Therapeutics22 citations
Semantic Scholar
Cerebrovascular reactivity to angiotensin and angiotensin-converting enzyme activity in cerebrospinal fluid.
E. Whalley, M. Wahl
1988Brain Research22 citations
Semantic Scholar
Analysis of the mechanism of action of bradykinin on human basilar artery in vitro
E. Whalley, Y. O. Amure, R. Lye
1987Naunyn-Schmiedeberg's Archives of Pharmacology22 citations
Semantic Scholar
Cerebrovascular effects of prostanoids: in-vitro studies in feline middle cerebral and basilar artery.
E. Whalley, L. Schilling, M. Wahl
1989Prostaglandins21 citations
Semantic Scholar
Analysis of bradykinin receptor mediating relaxation of cat cerebral arteries in vivo and in vitro
E. Whalley, Michael Wahl
1983Naunyn-Schmiedeberg's Archives of Pharmacology20 citations
Semantic Scholar
Pharmacological profiles of the human and rabbit B1 receptors.
F. Gobeil, W. Neugebauer, X. K. Nguyen-Le, S. Nsa Allogho +4 more
1997Canadian Journal of Physiology and Pharmacology19 citations
Semantic Scholar
Effects of Prostanoids on Human and Rabbit Basilar Arteries Precontracted In Vitro
A. A. Parsons, E. Whalley
1989Cephalalgia19 citations
Semantic Scholar
The Vasoconstrictor Action of Sumatriptan on Human Isolated Dura Mater
P. Humphrey, W. Feniuk, M. Motevalian, A. A. Parsons +1 more
199118 citations
Semantic Scholar
Characterization of the 5-hydroxytryptamine receptor which mediates contraction of the human isolated basilar artery
A. A. Parsons, E. Whalley
1989Cephalalgia17 citations
Semantic Scholar
The influence of drugs on the kinin-forming system in relation to pregnancy and parturition in the rat.
J. Senior, E. Whalley
1976Journal of Reproduction and Fertility17 citations Open access
Semantic Scholar
Kinin receptors and angiotensin converting enzyme in rabbits basilar arteries
E. Whalley, Hans Fritz, R. Geiger
1983Naunyn-Schmiedeberg's Archives of Pharmacology16 citations
Semantic Scholar
Dual A1/A2B Receptor Blockade Improves Cardiac and Renal Outcomes in a Rat Model of Heart Failure with Preserved Ejection Fraction
S. Tofovic, E. Salah, G. Smits, E. Whalley +3 more
2016Journal of Pharmacology and Experimental Therapeutics15 citations Open access
Semantic Scholar
Analysis of the receptors mediating vascular actions of bradykinin
E. Whalley, I. A. Nwator, John M. Stewart, R. Vavrek
1987Naunyn-Schmiedeberg's Archives of Pharmacology15 citations
Semantic Scholar
Effect of antagonists for NK(2)and B(2) receptors on antigen-induced airway responses in allergic rabbits.
Francis Woisin, T. Matsumoto, G. Douglas, William E. Paul +2 more
2000Pulmonary Pharmacology & Therapeutics11 citations
Semantic Scholar
Endogenous B1 receptor mediated hypotension produced by contact system activation in the presence of endotoxemia.
A. Schmid, S. Eich-Rathfelder, E. Whalley, J. Cheronis +3 more
1998Immunopharmacology10 citations
Semantic Scholar
Comparison of various prostaglandins (PG's) on the in vitro longitudinal uterine smooth muscle of the rat and guinea-pig.
E. Whalley, Susan K. White
1980British Journal of Pharmacology10 citations
Semantic Scholar
Renal effects of BG9928, an A1 adenosine receptor antagonist, in rats and nonhuman primates
B. Ticho, E. Whalley, A. Gill, Frank Lutterodt +3 more
20039 citations
Semantic Scholar
CHANGES IN PLASMA KININOGEN LEVELS INDUCED BY CELLULOSE SULPHATE DURING PREGNANCY IN THE RAT
J. T. McCormick, J. Senior, E. Whalley
1974British Journal of Pharmacology8 citations Open access
Semantic Scholar
The effect of kinins on paw oedema and uterus in rats
E. Whalley, C. A. Sampaio, Hans Fritz, G. Edwards
1984Naunyn-Schmiedeberg's Archives of Pharmacology7 citations
Semantic Scholar
Effect of an intra-uterine micro-balloon on the duration of parturition in the rat.
E. Whalley, A. Riley
1977Journal of Endocrinology7 citations
Semantic Scholar
Variation in the oestrogen-progesterone ratio and its effect on plasma kininogen levels in the rat.
J. Senior, E. Whalley
1974Journal of Reproduction and Fertility7 citations Open access
Semantic Scholar
Further Studies on the Mechanism of the Antimigraine Action of Sumatriptan
P. Humphrey, W. Feniuk, M. Perren, M. Skingle +2 more
19896 citations
Semantic Scholar
The effect of kininase II inhibitors on the response of feline cerebral arteries to bradykinin and angiotensin
E. Whalley, M. Wahl
1983Pflügers Archiv6 citations
Semantic Scholar
Design, synthesis, and analysis of a polyethelene glycol-modified (PEGylated) small molecule inhibitor of integrin {alpha}4{beta}1 with improved pharmaceutical properties.
R. Pepinsky, W.-C. Lee, M. Cornebise, A. Gill +14 more
2005Journal of Pharmacology and Experimental Therapeutics5 citations
Semantic Scholar
Tachyphylaxis of the B1 kinin receptor in porcine endotoxin shock.
Sabine Eich-Rathfelder, E. Whalley, Michael Fautz, Felix Hohenbleicher +2 more
1997Immunopharmacology5 citations
Semantic Scholar
Metabolism of bradykinin and angiotensin I by human basilar artery and rabbit aorta
E. Whalley
1987Naunyn-Schmiedeberg's Archives of Pharmacology5 citations
Semantic Scholar
Analysis of the 5-hydroxytryptamine induced contraction of the human basilar arterial strip compared with the rat aortic strip in vitro
C. Forster, E. Whalley
1982Naunyn-Schmiedeberg's Archives of Pharmacology5 citations
Semantic Scholar
Observations on the effect of labetalol on pregnancy and parturition in normotensive rats.
E. Whalley
1980General Pharmacology5 citations
Semantic Scholar
The effect of aprotinin on luteolytic and uterine contractile mechanisms in the pregnant rat at term.
E. Whalley, A. Riley
1979Journal of Reproduction and Fertility4 citations Open access
Semantic Scholar
The effect of pseudopregnancy and 'pseudoparturition' on the kinin system in the rat.
J. Senior, E. Whalley
1974Journal of Reproduction and Fertility4 citations Open access
Semantic Scholar
Bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers.
J. Cheronis, E. Whalley, J. K. Blodgett
1992Agents and actions. Supplements3 citations
Semantic Scholar
Cerebrovascular effects of prostanoids
Michael Wahl, L. Schilling, E. Whalley
1989Naunyn-Schmiedeberg's Archives of Pharmacology3 citations
Semantic Scholar

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A. Gill×6
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D. Lepage×4
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A. Chakraborty×3

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J. Relton — researcher profile on SciRah

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L. Schilling — researcher profile on SciRah

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R. Petter — researcher profile on SciRah

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D. Leone — researcher profile on SciRah

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W.-C. Lee — researcher profile on SciRah