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W. Feniuk · SciRah

Researcher profile · Semantic Scholar

W. Feniuk

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W. Feniuk — researcher profile on SciRah

h-index: 43
Works: 121
Citations: 7,368

Most-cited papers

Proposals for the classification and nomenclature of functional receptors for 5-hydroxytryptamine.
P. Bradley, G. Engel, W. Feniuk, J. Fozard +5 more
1986Neuropharmacology1,265 citations
Semantic Scholar
Classification and nomenclature of somatostatin receptors.
Daniel Hoyer, Graeme I. Bell, M. Berelowitz, J. Epelbaum +7 more
1995TIPS - Trends in Pharmacological Sciences553 citations Open access
Semantic Scholar
GR43175, a selective agonist for the 5‐HT1‐like receptor in dog isolated saphenous vein
P. Humphrey, W. Feniuk, M. Perren, H. E. Connor +3 more
1988British Journal of Pharmacology307 citations Open access
Semantic Scholar
Mode of action of the anti-migraine drug sumatriptan.
P. P. A. Humphrey, W. Feniuk
1991TIPS - Trends in Pharmacological Sciences246 citations
Semantic Scholar
5‐HT1‐like receptors mediate 5‐hydroxytryptamine‐induced contraction of human isolated basilar artery
Andrew A. Parsons, Eric T. Whalley, W. Feniuk, H. Connor +1 more
1989British Journal of Pharmacology176 citations Open access
Semantic Scholar
GR127935: a potent and selective 5-HT1D receptor antagonist.
M. Skingle, D. Beattie, D. Scopes, S. J. Starkey +3 more
1995Behavioural Brain Research174 citations Open access
Semantic Scholar
Preclinical studies on the anti-migraine drug, sumatriptan.
P. P. A. Humphrey, W. Feniuk, A. Marriott, R. J. N. Tanner +2 more
1991European Neurology172 citations
Semantic Scholar
5-Hydroxytryptamine contracts human coronary arteries predominantly via 5-HT2 receptor activation.
H. Connor, W. Feniuk, P. P. A. Humphrey
1989European Journal of Pharmacology160 citations
Semantic Scholar
The selective carotid arterial vasoconstrictor action of GR43175 in anaesthetized dogs
W. Feniuk, P. Humphrey, M. Perren
1989British Journal of Pharmacology152 citations Open access
Semantic Scholar
A Randomized, Double-Blind Comparison of Sumatriptan and Cafergot in the Acute Treatment of Migraine
P. P. A. Humphrey, W. Feniuk, A. Marriott, R. J. N. Tanner +14 more
1991146 citations
Semantic Scholar
Single-nucleotide polymorphism alleles in the insulin receptor gene are associated with typical migraine.
Linda C. McCarthy, D. Hosford, J. Riley, M. I. Bird +36 more
2001Genomics142 citations
Semantic Scholar
Characterization of 5‐HT receptors mediating contraction of canine and primate basilar artery by use of GR43175, a selective 5‐HT1‐like receptor agonist
H. Connor, W. Feniuk, P. Humphrey
1989British Journal of Pharmacology139 citations Open access
Semantic Scholar
Serotonin and Migraine
P. P. A. Humphrey, W. Feniuk, M. Perren, Isabel J. M. Beresford +2 more
1990Annals of the New York Academy of Sciences128 citations
Semantic Scholar
The Pharmacology of the Novel 5-HT1-Like Receptor Agonist, GR43175
P. Humphrey, W. Feniuk, M. Perren, H. Connor +1 more
1989Cephalalgia127 citations
Semantic Scholar
Sumatriptan An Oral Dose-Defining Study
P. Humphrey, W. Feniuk, A. Marriott, R. J. N. Tanner +14 more
1991124 citations
Semantic Scholar
Naratriptan
H. Connor, W. Feniuk, D. Beattie, PC North +3 more
1997Cephalalgia120 citations
Semantic Scholar
Evaluation of a multiple-dose regimen of oral sumatriptan for the acute treatment of migraine. The Oral Sumatriptan International Multiple-Dose Study Group.
P. P. A. Humphrey, W. Feniuk, A. Marriott, R. J. N. Tanner +14 more
1991European Neurology99 citations
Semantic Scholar
Evolution of a novel series of [(N,N-dimethylamino)propyl]- and piperazinylbenzanilides as the first selective 5-HT1D antagonists.
J. Clitherow, D. Scopes, M. Skingle, C. Jordan +6 more
1994Journal of Medicinal Chemistry95 citations Open access
Semantic Scholar
Self-treatment of acute migraine with subcutaneous sumatriptan using an auto-injector device. The Sumatriptan Auto-Injector Study Group.
P. P. A. Humphrey, W. Feniuk, A. Marriott, R. J. N. Tanner +14 more
1991European Neurology94 citations
Semantic Scholar
Effects of the 5-HT1D receptor antagonist GR127935 on extracellular levels of 5-HT in the guinea-pig frontal cortex as measured by microdialysis.
M. Skingle, Andrew J. Sleight, W. Feniuk
1995Neuropharmacology79 citations
Semantic Scholar
Characterization of the prostanoid receptor types involved in mediating calcitonin gene‐related peptide release from cultured rat trigeminal neurones
David W. Jenkins, W. Feniuk, P. P. A. Humphrey
2001British Journal of Pharmacology74 citations Open access
Semantic Scholar
5‐Carboxamidotryptamine is a selective agonist at 5‐hydroxytryptamine receptors mediating vasodilatation and tachycardia in anaesthetized cats
H. E. Connor, W. Feniuk, P. P. A. Humphrey, M. Perren
1986British Journal of Pharmacology72 citations Open access
Semantic Scholar
The selective closure of feline carotid arteriovenous anastomoses (AVAs) by GR43175
M. Perren, W. Feniuk, P. Humphrey
1989Cephalalgia71 citations
Semantic Scholar
Adenosine A(1) receptor-mediated inhibition of protein kinase A-induced calcitonin gene-related peptide release from rat trigeminal neurons.
Alan M. Carruthers, Lynda A. Sellers, David W. Jenkins, Emma M. Jarvie +2 more
2001Molecular Pharmacology68 citations
Semantic Scholar
A rational approach to identifying a fundamentally new drug for the treatment of migraine
P. P. A. Humphrey, E. Apperley, W. Feniuk, M. Perren
199060 citations
Semantic Scholar
Further characterization of the 5‐HT receptor mediating vascular relaxation and elevation of cyclic AMP in porcine isolated vena cava
M. J. Sumner, W. Feniuk, P. Humphrey
1989British Journal of Pharmacology57 citations Open access
Semantic Scholar
Activated G Protein-coupled Receptor Induces Tyrosine Phosphorylation of STAT3 and Agonist-selective Serine Phosphorylation via Sustained Stimulation of Mitogen-activated Protein Kinase
L. A. Sellers, W. Feniuk, P. Humphrey, H. Lauder
1999Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Selective somatostatin sst(2) receptor blockade with the novel cyclic octapeptide, CYN-154806.
W. Feniuk, Emma M. Jarvie, J. Luo, P. A. Humphrey
2000Neuropharmacology54 citations Open access
Semantic Scholar
A Placebo-Controlled Study of Intranasal Sumatriptan for the Acute Treatment of Migraine
P. P. A. Humphrey, W. Feniuk, A. Marriott, R. J. N. Tanner +14 more
199154 citations
Semantic Scholar
Stimulation of central 5-HT1D receptors causes hypothermia in the guinea-pig
M. Skingle, G. A. Higgins, W. Feniuk
1994Journal of Psychopharmacology53 citations
Semantic Scholar
Vascular 5‐HT1‐like receptors that mediate contraction of the dog isolated saphenous vein and carotid arterial vasoconstriction in anaesthetized dogs are not of the 5‐HT1A or 5‐HT1D subtype
M. Perren, W. Feniuk, P. P. A. Humphrey
1991British Journal of Pharmacology53 citations Open access
Semantic Scholar
5-Carboxamidotryptamine: a potent agonist mediating relaxation and elevation of cyclic AMP in the isolated neonatal porcine vena cava.
Michael A. Trevethick, W. Feniuk, P. P. A. Humphrey
1986Life Science53 citations
Semantic Scholar
Molecular cloning and functional characterization of a rat somatostatin sst2(b) receptor splice variant
M. Schindler, E. J. Kidd, Alan M. Carruthers, M. Wyatt +4 more
1998British Journal of Pharmacology49 citations Open access
Semantic Scholar
Effect of Sumatriptan, a Selective 5-HT1-like Receptor Agonist, on Pial Vessel Diameter in Anaesthetised Cats
H. Connor, C. M. Stubbs, W. Feniuk, P. Humphrey
1992Journal of Cerebral Blood Flow and Metabolism49 citations
Semantic Scholar
Role of endothelium in haemoglobin-induced contraction of dog basilar artery.
H. Connor, W. Feniuk
1987European Journal of Pharmacology47 citations
Semantic Scholar
Characterization of human recombinant somatostatin sst5 receptors mediating activation of phosphoinositide metabolism
G. Wilkinson, W. Feniuk, P. P. A. Humphrey
1997British Journal of Pharmacology46 citations Open access
Semantic Scholar
Influence of the endothelium on contractile effects of 5‐hydroxytryptamine and selective 5‐HT agonists in canine basilar artery
H. Connor, W. Feniuk
1989British Journal of Pharmacology46 citations Open access
Semantic Scholar
Characterization of somatostatin receptors in guinea‐pig isolated ileum, vas deferens and right atrium
W. Feniuk, J. Dimech, P. P. A. Humphrey
1993British Journal of Pharmacology43 citations Open access
Semantic Scholar
Anti‐Migraine Drugs in Development: Advances in Serotonin Receptor Pharmacology
P. Humphrey, W. Feniuk, M. Perren
1990Headache42 citations
Semantic Scholar
A quantitative autoradiographical study on the distribution of somatostatin sst2 receptors in the rat central nervous system using [125I]-BIM-23027.
Stanley Way, W. Feniuk, E. Kidd, P. A. Humphrey
1996Neuropharmacology40 citations
Semantic Scholar
Activation of adenylate cyclase by human recombinant sst5 receptors expressed in CHO‐K1 cells and involvement of Gαs proteins
Alan M. Carruthers, Andrea J. Warner, A. Michel, W. Feniuk +1 more
1999British Journal of Pharmacology39 citations Open access
Semantic Scholar
Somatostatin‐Induced Contraction of Human Isolated Saphenous Vein Involves sst2 Receptor‐Mediated Activation of L‐Type Calcium Channels
J. Dimech, W. Feniuk, R. Latimer, P. Humphrey
1995Journal of Cardiovascular Pharmacology39 citations Open access
Semantic Scholar
The development of a highly selective 5‐HT1 receptor agonist, sumatriptan, for the treatment of migraine
W. Feniuk, P. P. A. Humphrey
199238 citations
Semantic Scholar
Potent antagonism by BIM‐23056 at the human recombinant somatostatin sst5 receptor
G. Wilkinson, R. Thurlow, Lynda A. Sellers, J. Coote +2 more
1996British Journal of Pharmacology36 citations Open access
Semantic Scholar
Studies on the mechanism of 5‐HT1 receptor‐induced smooth muscle contraction in dog saphenous vein
M. J. Sumner, W. Feniuk, Julie D. McCormick, P. P. A. Humphrey
1992British Journal of Pharmacology36 citations Open access
Semantic Scholar
An investigation into the mechanisms of the cardiovascular effects of 5-hydroxytryptamine in conscious normotensive and DOCA-salt hypertensive rats.
D. W. Dalton, W. Feniuk, P. P. A. Humphrey
1986Journal of autonomic pharmacology36 citations
Semantic Scholar
Somatostatin5 receptor-mediated [35S]guanosine-5'-O-(3-thio)triphosphate binding: agonist potencies and the influence of sodium chloride on intrinsic activity.
Andrea J. Williams, A. Michel, W. Feniuk, P. P. A. Humphrey
1997Molecular Pharmacology35 citations
Semantic Scholar
Study of an Adenosine A1 Receptor Agonist on Trigeminally Evoked Dural Blood Vessel Dilation in the Anaesthetized Rat
AC Honey, PA Bland-Ward, H. Connor, W. Feniuk +1 more
2002Cephalalgia34 citations
Semantic Scholar
The pivotal role of phosphoinositide-3 kinase in the human somatostatin sst(4) receptor-mediated stimulation of p44/p42 mitogen-activated protein kinase and extracellular acidification.
K. Smalley, W. Feniuk, Lynda A. Sellers, P. P. A. Humphrey
1999Biochemical and Biophysical Research Communications - BBRC33 citations
Semantic Scholar
Analysis of the 5‐HT receptors mediating contractions in the rabbit isolated renal artery
S. Tadipatri, D. Heuven-Nolsen, W. Feniuk, P. R. Saxena
1991British Journal of Pharmacology33 citations Open access
Semantic Scholar

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