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Siraj M. Ali · SciRah

Researcher profile · Semantic Scholar

Siraj M. Ali

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Siraj M. Ali — researcher profile on SciRah

h-index: 89
Works: 674
Citations: 46K

Most-cited papers

Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies.
A. Necchi, D. Raggi, A. Gallina, R. Madison +20 more
2019European Urology307 citations
Semantic Scholar
AENEAS: A Randomized Phase III Trial of Aumolertinib Versus Gefitinib as First-Line Therapy for Locally Advanced or MetastaticNon–Small-Cell Lung Cancer With EGFR Exon 19 Deletion or L858R Mutations
Shun Lu, Xiao-Rong Dong, H. Jian, Jian-Hua Chen +55 more
2022Journal of Clinical Oncology263 citations Open access
Semantic Scholar
Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma
M. Gounder, N. Agaram, S. Trabucco, V. Robinson +39 more
2022Nature Communications185 citations Open access
Semantic Scholar
Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma
C. Ang, S. Klempner, Siraj M. Ali, R. Madison +7 more
2019OncoTarget160 citations Open access
Semantic Scholar
Pan-Cancer Analysis of BRCA1 and BRCA2 Genomic Alterations and Their Association With Genomic Instability as Measured by Genome-Wide Loss of Heterozygosity
E. Sokol, D. Pavlick, Hossein Khiabanian, G. Frampton +11 more
2020JCO Precision Oncology149 citations Open access
Semantic Scholar
Prospective Comprehensive Genomic Profiling of Primary and Metastatic Prostate Tumors
J. Chung, N. Dewal, E. Sokol, P. Mathew +14 more
2019JCO Precision Oncology144 citations Open access
Semantic Scholar
Clinicopathologic Characteristics of BRG1-Deficient Non-Small Cell Lung Cancer.
I. Dagogo-Jack, A. Schrock, M. Kem, Nicholas A. Jessop +6 more
2020Journal of Thoracic Oncology108 citations Open access
Semantic Scholar
Comprehensive Genomic Profiling of Upper-tract and Bladder Urothelial Carcinoma.
A. Necchi, R. Madison, S. Pal, J. Ross +8 more
2020European Urology Focus95 citations Open access
Semantic Scholar
On-target resistance to the mutant-selective EGFR inhibitor osimertinib can develop in an allele specific manner dependent on the original EGFR activating mutation
Benjamin P. Brown, Yun-Kai Zhang, D. Westover, Ying Yan +11 more
2019Clinical Cancer Research95 citations Open access
Semantic Scholar
Comparative Genomic Profiling of Refractory and Metastatic Penile and Nonpenile Cutaneous Squamous Cell Carcinoma: Implications for Selection of Systemic Therapy
J. Jacob, E. Ferry, L. Gay, J. Elvin +15 more
2019Journal of Urology85 citations
Semantic Scholar
Clinicopathologic Features and Response to Therapy of NRG1 Fusion–Driven Lung Cancers: The eNRGy1 Global Multicenter Registry
A. Drilon, M. Duruisseaux, Ji-Youn Han, M. Ito +32 more
2021Journal of Clinical Oncology70 citations Open access
Semantic Scholar
An Open-label Randomized Phase 2 study of Durvalumab Alone or in Combination with Tremelimumab in Patients with Advanced Germ Cell Tumors (APACHE): Results from the First Planned Interim Analysis.
A. Necchi, P. Giannatempo, D. Raggi, L. Mariani +8 more
2019European Urology65 citations
Semantic Scholar
Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
D. Zingg, J. Bhin, Julia Yemelyanenko, S. Kas +44 more
2022Nature63 citations Open access
Semantic Scholar
The Genomics of Colorectal Cancer in Populations with African and European Ancestry.
P. Myer, Jessica K. Lee, R. Madison, K. Pradhan +14 more
2022Cancer Discovery61 citations Open access
Semantic Scholar
Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting
Z. Du, Benjamin P. Brown, Soyeon Kim, D. Ferguson +14 more
2021Nature Communications61 citations Open access
Semantic Scholar
Comprehensive Assessment of Immuno-oncology Biomarkers in Adenocarcinoma, Urothelial Carcinoma, and Squamous-cell Carcinoma of the Bladder.
A. Necchi, R. Madison, D. Raggi, J. Jacob +19 more
2020European Urology58 citations
Semantic Scholar
Characterization of Clinical Cases of Malignant PEComa via Comprehensive Genomic Profiling of DNA and RNA
Saranya Akumalla, R. Madison, D. Lin, A. Schrock +10 more
2020Oncology57 citations
Semantic Scholar
Positive Association Between Location of Melanoma, Ultraviolet Signature, Tumor Mutational Burden, and Response to Anti–PD-1 Therapy
L. Dousset, F. Poizeau, C. Robert, S. Mansard +24 more
2021JCO Precision Oncology56 citations Open access
Semantic Scholar
Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer
S. Nanjo, Wei Wu, N. Karachaliou, C. Blakely +24 more
2020bioRxiv54 citations Open access
Semantic Scholar
Genomic profiling of BCOR-rearranged uterine sarcomas reveals novel gene fusion partners, frequent CDK4 amplification and CDKN2A loss.
D. Lin, A. Hemmerich, C. Edgerly, D. Duncan +10 more
2020Gynecologic Oncology54 citations
Semantic Scholar
Responsiveness to immune checkpoint inhibitors versus other systemic therapies in RET-aberrant malignancies
A. Hegde, Alexander Y. Andreev-Drakhlin, J. Roszik, Le Huang +18 more
2020ESMO Open48 citations Open access
Semantic Scholar
Urothelial Cancers with Small Cell Variant Histology Have Confirmed High Tumor Mutational Burden, Frequent TP53 and RB Mutations, and a Unique Gene Expression Profile.
J. Hoffman-Censits, Woonyoung Choi, S. Pal, E. Trabulsi +11 more
2020European Urology Oncology42 citations
Semantic Scholar
Targetable gene fusions and aberrations in genitourinary oncology
F. Pederzoli, M. Bandini, L. Marandino, Siraj M. Ali +4 more
2020Nature reviews. Urology42 citations
Semantic Scholar
Genomic Characterization of Testicular Germ Cell Tumors Relapsing After Chemotherapy.
A. Necchi, G. Bratslavsky, R. Corona, J. Chung +15 more
2020European Urology Focus41 citations
Semantic Scholar
Predicting the pathologic complete response after neoadjuvant pembrolizumab in muscle-invasive bladder cancer.
M. Bandini, J. Ross, D. Raggi, A. Gallina +19 more
2020Journal of the National Cancer Institute40 citations Open access
Semantic Scholar
Clinical and immunological implications of frameshift mutations in lung cancer.
Y. Chae, P. Viveiros, G. Lopes, B. Sukhadia +21 more
2019Journal of Thoracic Oncology40 citations Open access
Semantic Scholar
CLINICAL AND GENOMIC CHARACTERISTICS OF SMALL CELL LUNG CANCER IN NEVER-SMOKERS: RESULTS FROM A RETROSPECTIVE MULTICENTER COHORT STUDY.
Anish Thomas, Idrees Mian, C. Tlemsani, L. Pongor +19 more
2020Chest37 citations Open access
Semantic Scholar
Unique mutation patterns in anaplastic thyroid cancer identified by comprehensive genomic profiling
Saad A. Khan, Ci Bo, Yang Xie, D. Gerber +10 more
2019Head and Neck34 citations Open access
Semantic Scholar
Genomic profiling of cell-free circulating tumor DNA in patients with colorectal cancer and its fidelity to the genomics of the tumor biopsy.
Gerald Li, D. Pavlick, J. Chung, T. Bauer +19 more
2019Journal of Gastrointestinal Oncology34 citations Open access
Semantic Scholar
Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
D. Zingg, J. Bhin, Julia Yemelyanenko, S. Kas +44 more
2022Nature33 citations Open access
Semantic Scholar
Cyclin Pathway Genomic Alterations Across 190,247 Solid Tumors: Leveraging Large‐Scale Data to Inform Therapeutic Directions
D. Jardim, S. Millis, J. Ross, M. Woo +2 more
2020The Oncologist33 citations Open access
Semantic Scholar
Targetable BRAF and RAF1 alterations in advanced pediatric cancers.
A. Rankin, A. Johnson, Alison Roos, G. Kannan +18 more
2020The Oncologist32 citations Open access
Semantic Scholar
FGFR2‐Altered Gastroesophageal Adenocarcinomas Are an Uncommon Clinicopathologic Entity with a Distinct Genomic Landscape
S. Klempner, R. Madison, V. Pujara, J. Ross +9 more
2019The Oncologist30 citations Open access
Semantic Scholar
Differential response to a combination of full-dose osimertinib and crizotinib in a patient with EGFR-mutant non-small cell lung cancer and emergent MET amplification
Viola W. Zhu, A. Schrock, Siraj M. Ali, S. Ou
2019Lung Cancer30 citations Open access
Semantic Scholar
Genomic Profiling of Combined Hepatocellular Cholangiocarcinoma Reveals Genomics Similar to Either Hepatocellular Carcinoma or Cholangiocarcinoma
K. Murugesan, Radwa Sharaf, M. Montesion, J. Moore +11 more
2021JCO Precision Oncology29 citations Open access
Semantic Scholar
Retrospective analysis of real-world data to determine clinical outcomes of patients with advanced non-small cell lung cancer following cell-free circulating tumor DNA genomic profiling.
R. Madison, A. Schrock, E. Castellanos, J. Gregg +7 more
2020Lung Cancer27 citations Open access
Semantic Scholar
The Pan‐Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA
U. Disel, R. Madison, K. Abhishek, J. Chung +30 more
2019The Oncologist27 citations Open access
Semantic Scholar
Urothelial cancer harbours EGFR and HER2 amplifications and exon 20 insertions
R. Madison, Sumati V. Gupta, Y. Elamin, D. Lin +10 more
2020BJU International24 citations
Semantic Scholar
Recurrent secondary genomic alterations in desmoplastic small round cell tumors
W. Chow, Jiing-kuan Yee, W. Tsark, Xi-Wei Wu +5 more
2020BMC Medical Genetics21 citations Open access
Semantic Scholar
Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib
Mohammed Hassan, E. Butler, Raphael A. Wilson, A. Roy +12 more
2019Cold Spring Harbor molecular case studies21 citations Open access
Semantic Scholar
Unfavourable cancer specific survival after neoadjuvant chemotherapy and radical cystectomy in bladder cancer patients with squamous-cell variant: A multi-institutional study
M. Bandini, F. Pederzoli, R. Madison, A. Briganti +17 more
2020Clinical Genitourinary Cancer20 citations Open access
Semantic Scholar
Optimized EGFR Blockade Strategies in EGFR Addicted Gastroesophageal Adenocarcinomas
S. Corso, F. Pietrantonio, M. Apicella, C. Migliore +38 more
2021Clinical Cancer Research18 citations Open access
Semantic Scholar
TNS1-ALK Fusion in a Recurrent, Metastatic Uterine Mesenchymal Tumor Originally Diagnosed as Leiomyosarcoma.
Jessica K. Lee, Arun S. Singh, Siraj M. Ali, D. Lin +1 more
2019Acta Medica Academica18 citations Open access
Semantic Scholar
Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors
J. Riess, Shaila Rahman, W. Kian, C. Edgerly +19 more
2021Translational Oncology17 citations Open access
Semantic Scholar
Real-world association of HER2/ERBB2 concordance with trastuzumab clinical benefit in advanced esophagogastric cancer.
S. Stein, J. Snider, Siraj M. Ali, R. Miksad +7 more
2021Future Oncology16 citations Open access
Semantic Scholar
Squamous Transformation of Prostate Adenocarcinoma: A Report of Two Cases With Genomic Profiling.
N. Dizman, M. Salgia, Siraj M. Ali, Hui-Qing Wu +3 more
2019Clinical Genitourinary Cancer14 citations
Semantic Scholar
265P Study of samuraciclib (CT7001), a first-in-class, oral, selective inhibitor of CDK7, in combination with fulvestrant in patients with advanced hormone receptor positive HER2 negative breast cancer (HR+BC)
S. Howell, M. Krebs, S. Lord, L. Kenny +16 more
2021Annals of Oncology11 citations Open access
Semantic Scholar
Comprehensive Landscape of Cyclin Pathway Gene Alterations and Co-occurrence with FGF/FGFR Aberrations Across Urinary Tract Tumors
D. Jardim, S. Millis, J. Ross, S. Lippman +2 more
2022The Oncologist9 citations Open access
Semantic Scholar
Tumor mutational burden and response to programmed cell death protein 1 inhibitors in a case series of patients with metastatic desmoplastic melanoma.
L. Boussemart, A. Johnson, A. Schrock, S. Pal +11 more
2019Journal of American Academy of Dermatology9 citations Open access
Semantic Scholar
NRG1 fusion-positive lung cancers: Clinicopathologic profile and treatment outcomes from a global multicenter registry.
M. Duruisseaux, Stephen V. Liu, Ji-Youn Han, V. Gounant +14 more
2019Journal of Clinical Oncology9 citations
Semantic Scholar

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