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Ying Yan · SciRah

Researcher profile · Semantic Scholar

Ying Yan

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Ying Yan — researcher profile on SciRah

h-index: 35
Works: 120
Citations: 4,778

Most-cited papers

Rationale for co-targeting IGF-1R and ALK in ALK fusion positive lung cancer
C. Lovly, Nerina T. McDonald, Heidi Chen, S. Ortiz-Cuàran +35 more
2014Nature Medicine267 citations Open access
Semantic Scholar
Radiation-induced signaling pathways that promote cancer cell survival (Review)
Ashley L. Hein, M. Ouellette, Ying Yan
2014International Journal of Oncology182 citations Open access
Semantic Scholar
Longitudinal cell-free DNA analysis in patients with small cell lung cancer reveals dynamic insights into treatment efficacy and disease relapse
K. Almodovar, W. Iams, C. Meador, Zhi-Guo Zhao +9 more
2017Journal of Thoracic Oncology136 citations Open access
Semantic Scholar
SFK/FAK signaling attenuates osimertinib efficacy in both drug-sensitive and drug-resistant models of EGFR-mutant lung cancer
E. Ichihara, D. Westover, C. Meador, Ying Yan +10 more
2017Cancer Research124 citations Open access
Semantic Scholar
EGFR fusions as novel therapeutic targets in lung cancer
K. Konduri, Jean-Nicolas Gallant, Y. Chae, F. Giles +20 more
2016Cancer Discovery118 citations Open access
Semantic Scholar
Biological determinants of radioresistance and their remediation in pancreatic cancer
P. Seshacharyulu, M. Baine, J. Souchek, M. Menning +6 more
2017Biochimica et biophysica acta. Reviews on cancer109 citations Open access
Semantic Scholar
BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1
Zhen-Feng Zhang, Peng-Fei Ma, Y. Jing, Ying Yan +9 more
2016Theranostics100 citations Open access
Semantic Scholar
On-target resistance to the mutant-selective EGFR inhibitor osimertinib can develop in an allele specific manner dependent on the original EGFR activating mutation
Benjamin P. Brown, Yun-Kai Zhang, D. Westover, Ying Yan +11 more
2019Clinical Cancer Research95 citations Open access
Semantic Scholar
Telomerase Inhibitor Imetelstat (GRN163L) Limits the Lifespan of Human Pancreatic Cancer Cells
Katrina M. Burchett, Ying Yan, M. Ouellette
2014PLoS ONE81 citations Open access
Semantic Scholar
TLR9 expression in glioma tissues correlated to glioma progression and the prognosis of GBM patients
Chao Wang, Shou-Qiang Cao, Ying Yan, Qiao Ying +3 more
2010BMC Cancer74 citations Open access
Semantic Scholar
RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment
Ashley L. Hein, Carl M. Post, Y. Sheinin, Imayavaramban Lakshmanan +5 more
2016Oncogene71 citations Open access
Semantic Scholar
Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer
Peng-Fei Ma, Yu-Jie Fu, Mei-Chun Cai, Ying Yan +13 more
2017Nature Communications66 citations Open access
Semantic Scholar
PR55α subunit of protein phosphatase 2A supports the tumorigenic and metastatic potential of pancreatic cancer cells by sustaining hyperactive oncogenic signaling
Ashley L. Hein, P. Seshacharyulu, S. Rachagani, Y. Sheinin +5 more
2016Cancer Research65 citations Open access
Semantic Scholar
Structure–function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting
Z. Du, Benjamin P. Brown, Soyeon Kim, D. Ferguson +14 more
2021Nature Communications61 citations Open access
Semantic Scholar
RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation
Ying Yan, P. M. Greer, P. Cao, R. Kolb +1 more
2012Breast Cancer Research59 citations Open access
Semantic Scholar
Human age‑related cataracts: epigenetic suppression of the nuclear factor erythroid 2‑related factor 2‑mediated antioxidant system.
Yun-Xia Gao, Ying Yan, Tingfen Huang
2015Molecular Medicine Reports53 citations Open access
Semantic Scholar
Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer
P. Seshacharyulu, M. Ponnusamy, S. Rachagani, Imayavaramban Lakshmanan +4 more
2014OncoTarget48 citations Open access
Semantic Scholar
Quantitative Receptor-Based Imaging of Tumor Proliferation with the Sigma-2 Ligand [18F]ISO-1
K. Shoghi, Jin-Bin Xu, Yi Su, June He +10 more
2013PLoS ONE45 citations Open access
Semantic Scholar
Resveratrol-induced cytotoxicity in human Burkitt's lymphoma cells is coupled to the unfolded protein response
Ying Yan, Yan-Yan Gao, Bao-Qin Liu, Xiao-Fang Niu +2 more
2010BMC Cancer42 citations Open access
Semantic Scholar
PAX8 regulon in human ovarian cancer links lineage dependency with epigenetic vulnerability to HDAC inhibitors
Kaixuan Shi, Xiaobin Yin, Mei-Chun Cai, Ying Yan +8 more
2019eLife40 citations Open access
Semantic Scholar
Inhibition of BRCT(BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of Olaparib in breast cancer cells: A proof of concept study for synthetic lethal therapeutic option
Ziyan Y. Pessetto, Ying Yan, T. Bessho, A. Natarajan
2012Breast Cancer Research and Treatment39 citations Open access
Semantic Scholar
Proteasome inhibition induces a p38 MAPK pathway-dependent antiapoptotic program via Nrf2 in thyroid cancer cells.
Zhen-Xian Du, Ying Yan, Hai-yan Zhang, Bao-Qin Liu +4 more
2011Journal of Clinical Endocrinology and Metabolism39 citations
Semantic Scholar
Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation
Ying Yan, Ashley L. Hein, Asserewou Etekpo, Katrina M. Burchett +5 more
2014OncoTarget38 citations Open access
Semantic Scholar
PTD4‐apoptin protein therapy inhibits tumor growth in vivo
Jun Sun, Ying Yan, Xiao-Ting Wang, Xiao-Wen Liu +7 more
2009International Journal of Cancer36 citations Open access
Semantic Scholar
Osthole enhances antitumor activity and irradiation sensitivity of cervical cancer cells by suppressing ATM/NF-κB signaling
Yilin Che, Juan Li, Zong-Juan Li, Jing Li +4 more
2018Oncology Report35 citations Open access
Semantic Scholar
Novel HER3/MUC4 oncogenic signaling aggravates the tumorigenic phenotypes of pancreatic cancer cells
Imayavaramban Lakshmanan, P. Seshacharyulu, D. Haridas, S. Rachagani +8 more
2015OncoTarget35 citations Open access
Semantic Scholar
ERK1/2 Signaling Plays an Important Role in Topoisomerase II Poison-Induced G2/M Checkpoint Activation
R. Kolb, P. M. Greer, P. Cao, K. Cowan +1 more
2012PLoS ONE34 citations Open access
Semantic Scholar
PR55α regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells
Ashley L. Hein, Nichole D. Brandquist, Caroline Y. Ouellette, P. Seshacharyulu +4 more
2019Oncogenesis33 citations Open access
Semantic Scholar
Discovery and characterization of small molecule Rac1 inhibitors
Jamie L. Arnst, Ashley L. Hein, M. Taylor, Nick Palermo +6 more
2017OncoTarget28 citations Open access
Semantic Scholar
γ-Irradiation–Induced DNA Damage Checkpoint Activation Involves Feedback Regulation between Extracellular Signal-Regulated Kinase 1/2 and BRCA1
Ying Yan, C. P. Black, P. Cao, Jamie L Haferbier +4 more
2008Cancer Research27 citations Open access
Semantic Scholar
Anti-Inflammatory Effects of HDL in Mice With Rheumatoid Arthritis Induced by Collagen
Yun-Long Wang, Shu-Lai Lu, Guoqing Zhang, Shaofeng Wu +3 more
2018Frontiers in Immunology26 citations Open access
Semantic Scholar
Preparation and passive target of 5-fluorouracil solid lipid nanoparticles
B. Du, Ying Yan, Ying Li, Shu-yu Wang +1 more
2009Pharmaceutical development and technology (Print)26 citations
Semantic Scholar
Beyond PD-L1: B7-H6 emerges as a potential immunotherapy target in small cell lung cancer
P. Thomas, S. Groves, Yun-Kai Zhang, Jia Li +15 more
2021Journal of Thoracic Oncology23 citations Open access
Semantic Scholar
Blood-Based Surveillance Monitoring of Circulating Tumor DNA From Patients With SCLC Detects Disease Relapse and Predicts Death in Patients With Limited-Stage Disease
W. Iams, Prasad Kopparapu, Ying Yan, A. Muterspaugh +14 more
2020JTO Clinical and Research Reports23 citations Open access
Semantic Scholar
Implication of 14‐3‐3ε and 14‐3‐3θ/τ in proteasome inhibition‐induced apoptosis of glioma cells
Ying Yan, Ying Xu, Yan-Yan Gao, Z. Zong +3 more
2013Cancer Science23 citations Open access
Semantic Scholar
SPNS2 Downregulation Induces EMT and Promotes Colorectal Cancer Metastasis via Activating AKT Signaling Pathway
L. Lv, Qi-Yi Yi, Ying Yan, Fengmei Chao +1 more
2021Frontiers in Oncology20 citations Open access
Semantic Scholar
Suppression of MG132-mediated cell death by peroxiredoxin 1 through influence on ASK1 activation in human thyroid cancer cells.
Zhen-Xian Du, Ying Yan, Hai-yan Zhang, Bao-Qin Liu +5 more
2010Endocrine-Related Cancer19 citations
Semantic Scholar
Circulating Tumor DNA as a Biomarker of Radiographic Tumor Burden in SCLC
Jarrod T. Smith, A. Balar, D. Lakhani, C. Kluwe +18 more
2020JTO Clinical and Research Reports18 citations Open access
Semantic Scholar
Transcriptomic analysis by RNA‐seq reveals AP‐1 pathway as key regulator that green tea may rely on to inhibit lung tumorigenesis
Jing Pan, Qi Zhang, Dong-Hai Xiong, P. Vedell +8 more
2014Molecular Carcinogenesis18 citations
Semantic Scholar
Inhibition of poly(ADP‐ribose) polymerase (PARP) and ataxia telangiectasia mutated (ATM) on the chemosensitivity of mantle cell lymphoma to agents that induce DNA strand breaks
Radha M. Golla, Min Li, Yu-Lei Shen, M. Ji +5 more
2012Hematological Oncology18 citations
Semantic Scholar
Rac1 GTPase in pancreatic cancer
Ying Yan, M. Ouellette
2015Aging17 citations Open access
Semantic Scholar
Amyloid precursor-like protein 2 suppresses irradiation-induced apoptosis in Ewing sarcoma cells and is elevated in immune-evasive Ewing sarcoma cells
Haley L. Peters, Ying Yan, T. Nordgren, Christine E. Cutucache +2 more
2013Cancer Biology & Therapy17 citations Open access
Semantic Scholar
Effect and Mechanism of miR-26a-5p on Proliferation and Apoptosis of Hepatocellular Carcinoma Cells
Wenshuai Zhu, Ying Yan, Jiuchang Zhang, Yandong Tang +1 more
2020Cancer Management and Research15 citations Open access
Semantic Scholar
Sensitisation of human lung adenocarcinoma A549 cells to radiotherapy by Nimotuzumab is associated with enhanced apoptosis and cell cycle arrest in the G2/M phase
Shan Lin, Ying Yan, Yuan Liu, Chun-Zi Gao +3 more
2015Cell Biology International15 citations
Semantic Scholar
The OB-fold domain 1 of human POT1 recognizes both telomeric and non-telomeric DNA motifs
K. H. Choi, Amanda S Lakamp-Hawley, Carol Kolar, Ying Yan +2 more
2015Biochimie15 citations Open access
Semantic Scholar
A dominant negative c-jun mutant inhibits lung carcinogenesis in mice
J. Tichelaar, Ying Yan, Q. Tan, Yian Wang +7 more
2010Cancer Prevention Research15 citations Open access
Semantic Scholar
ΜiR-182-5p functions as a tumor suppressor to sensitize human ovarian cancer cells to cisplatin through direct targeting the cyclin dependent kinase 6 (CDK6).
L. Duan, Ying Yan, Guan Wang, Y. Xing +2 more
2020Journal of B.U.ON. : official journal of the Balkan Union of Oncology14 citations
Semantic Scholar
Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells
Katrina M. Burchett, Asserewou Etekpo, S. Batra, Ying Yan +1 more
2017OncoTarget14 citations Open access
Semantic Scholar
Rac1 is a novel therapeutic target in mantle cell lymphoma
T. Tian, Chengfeng Bi, Ashley L. Hein, Xuan Zhang +8 more
2018Blood Cancer Journal13 citations Open access
Semantic Scholar
The histone deacetylase inhibitor M344 as a multifaceted therapy for pancreatic cancer
S. Knoche, Gabrielle L Brumfield, Benjamin T. Goetz, Bailee H. Sliker +7 more
2022PLoS ONE12 citations Open access
Semantic Scholar

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