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A. Boddy · SciRah

Researcher profile · Semantic Scholar

A. Boddy

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A. Boddy — researcher profile on SciRah

h-index: 39
Works: 203
Citations: 6,378

Most-cited papers

A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours
Ruth Plummer, R. Wilson, H. Calvert, A. Boddy +9 more
2011British Journal of Cancer366 citations Open access
Semantic Scholar
Phase 2 multicentre trial investigating intermittent and continuous dosing schedules of the poly(ADP-ribose) polymerase inhibitor rucaparib in germline BRCA mutation carriers with advanced ovarian and breast cancer
Y. Drew, J. Ledermann, G. Hall, D. Rea +13 more
2016British Journal of Cancer160 citations Open access
Semantic Scholar
Curcumin as a clinically-promising anti-cancer agent: pharmacokinetics and drug interactions
Jeffry Adiwidjaja, A. McLachlan, A. Boddy
2017Expert Opinion on Drug Metabolism & Toxicology154 citations
Semantic Scholar
Imagestream detection and characterisation of circulating tumour cells - A liquid biopsy for hepatocellular carcinoma?
L. Ogle, James G. Orr, Catherine E. Willoughby, C. Hutton +6 more
2016Journal of Hepatology116 citations Open access
Semantic Scholar
Efficacy of PARP inhibitor rucaparib in orthotopic glioblastoma xenografts is limited by ineffective drug penetration into the central nervous system
Karen E. Parrish, L. Cen, James W Murray, David Calligaris +10 more
2015Molecular Cancer Therapeutics82 citations Open access
Semantic Scholar
Formulation of Biologically-Inspired Silk-Based Drug Carriers for Pulmonary Delivery Targeted for Lung Cancer
Sally Yunsun Kim, Deboki Naskar, S. Kundu, D. Bishop +5 more
2015Scientific Reports59 citations Open access
Semantic Scholar
Interactions between natural products and cancer treatments: underlying mechanisms and clinical importance
W. J. Chan, Jeffry Adiwidjaja, A. McLachlan, A. Boddy +1 more
2023Cancer Chemotherapy and Pharmacology56 citations Open access
Semantic Scholar
Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma
G. Veal, J. Errington, Sophie E Rowbotham, Nicola A. Illingworth +5 more
2012Clinical Cancer Research56 citations Open access
Semantic Scholar
Cyclophosphamide pharmacokinetics and pharmacogenetics in children with B-cell non-Hodgkin's lymphoma
G. Veal, M. Cole, G. Chinnaswamy, J. Sludden +6 more
2016European Journal of Cancer54 citations Open access
Semantic Scholar
A Phase I Trial of AT9283 (a Selective Inhibitor of Aurora Kinases) in Children and Adolescents with Solid Tumors: A Cancer Research UK Study
L. Moreno, L. Marshall, A. Pearson, B. Morland +14 more
2014Clinical Cancer Research52 citations Open access
Semantic Scholar
Thiothymidine combined with UVA as a potential novel therapy for bladder cancer
S. Pridgeon, R. Heer, G. Taylor, D. Newell +5 more
2011British Journal of Cancer48 citations Open access
Semantic Scholar
High‐resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers
B. Dent, L. Ogle, R. O'Donnell, Nicholas Hayes +8 more
2015International Journal of Cancer47 citations Open access
Semantic Scholar
Characterisation of the Clinical Pharmacokinetics of Actinomycin D and the Influence of ABCB1 Pharmacogenetic Variation on Actinomycin D Disposition in Children with Cancer
C. R. Hill, M. Cole, J. Errington, G. Malik +2 more
2014Clinical Pharmacokinetics42 citations Open access
Semantic Scholar
Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years
Nina E. Kontny, G. Würthwein, Boos Joachim, A. Boddy +6 more
2013Cancer Chemotherapy and Pharmacology42 citations Open access
Semantic Scholar
Characterisation of the roles of ABCB1, ABCC1, ABCC2 and ABCG2 in the transport and pharmacokinetics of actinomycin D in vitro and in vivo
C. R. Hill, D. Jamieson, H. Thomas, C. Brown +2 more
2013Biochemical Pharmacology40 citations Open access
Semantic Scholar
Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics
Jeffry Adiwidjaja, A. Boddy, A. McLachlan
2020Frontiers in Pharmacology38 citations Open access
Semantic Scholar
Two minor NQO1 and NQO2 alleles predict poor response of breast cancer patients to adjuvant doxorubicin and cyclophosphamide therapy
D. Jamieson, N. Cresti, J. Bray, J. Sludden +7 more
2011Pharmacogenetics & Genomics38 citations Open access
Semantic Scholar
A Retinol Isotope Dilution Equation Predicts Both Group and Individual Total Body Vitamin A Stores in Adults Based on Data from an Early Postdosing Blood Sample
M. H. Green, J. Ford, J. B. Green, P. Berry +3 more
2016Journal of NutriLife37 citations Open access
Semantic Scholar
Pharmacogenetics of adjuvant breast cancer treatment with cyclophosphamide, epirubicin and 5-fluorouracil
D. Jamieson, J. Lee, N. Cresti, Rosanna K. Jackson +4 more
2014Cancer Chemotherapy and Pharmacology36 citations Open access
Semantic Scholar
Pharmacogenetics of genes across the doxorubicin pathway
D. Jamieson, A. Boddy
2011Expert Opinion on Drug Metabolism & Toxicology36 citations Open access
Semantic Scholar
Phase II trial of the poly(ADP-ribose) polymerase (PARP) inhibitor AG-014699 in BRCA 1 and 2-mutated, advanced ovarian and/or locally advanced or metastatic breast cancer.
Y. Drew, J. Ledermann, Andrew J. I. Jones, G. Hall +10 more
2011Journal of Clinical Oncology35 citations
Semantic Scholar
Is there scope for better individualisation of anthracycline cancer chemotherapy?
B. Sallustio, A. Boddy
2020British Journal of Clinical Pharmacology34 citations
Semantic Scholar
An LC/MS/MS method for stable isotope dilution studies of β-carotene bioavailability, bioconversion, and vitamin A status in humans[S]
Anthony Oxley, P. Berry, G. A. Taylor, Joseph Cowell +4 more
2014Journal of Lipid Research34 citations Open access
Semantic Scholar
Pharmacokinetic and pharmacodynamic study of doxorubicin in children with cancer: results of a “European Pediatric Oncology Off-patents Medicines Consortium” trial
M. Krischke, G. Hempel, S. Völler, N. André +7 more
2016Cancer Chemotherapy and Pharmacology31 citations Open access
Semantic Scholar
Chemotherapy in newborns and preterm babies.
G. Veal, A. Boddy
2012Seminars in Fetal & Neonatal Medicine29 citations Open access
Semantic Scholar
A phase I/II trial of AT9283, a selective inhibitor of aurora kinase in children with relapsed or refractory acute leukemia: challenges to run early phase clinical trials for children with leukemia
B. Vormoor, G. Veal, M. Griffin, A. Boddy +17 more
2017Pediatric Blood & Cancer28 citations Open access
Semantic Scholar
Plasma Retinol Kinetics and β-Carotene Bioefficacy Are Quantified by Model-Based Compartmental Analysis in Healthy Young Adults with Low Vitamin A Stores
M. H. Green, J. Ford, Anthony Oxley, J. B. Green +4 more
2016Journal of NutriLife28 citations Open access
Semantic Scholar
Physiologically Based Pharmacokinetic Modelling of Hyperforin to Predict Drug Interactions with St John’s Wort
Jeffry Adiwidjaja, A. Boddy, A. McLachlan
2019Clinical Pharmacokinetics26 citations Open access
Semantic Scholar
Precision dosing of targeted anticancer drugs—challenges in the real world
H. Kim, Jennifer H. Martin, A. McLachlan, A. Boddy
201726 citations
Semantic Scholar
Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer
Christopher S. Walsh, J. Bonner, T. Johnson, S. Neuhoff +4 more
2016British Journal of Clinical Pharmacology26 citations Open access
Semantic Scholar
Age-Dependent Pharmacokinetics of Doxorubicin in Children with Cancer
S. Völler, J. Boos, M. Krischke, G. Würthwein +3 more
2015Clinical Pharmacokinetics26 citations Open access
Semantic Scholar
Monte Carlo simulations of the clinical benefits from therapeutic drug monitoring of sunitinib in patients with gastrointestinal stromal tumours
S. C. Goulooze, P. Galettis, A. Boddy, Jennifer H. Martin
2016Cancer Chemotherapy and Pharmacology23 citations
Semantic Scholar
Pharmacokinetic and cytokine profiles of melanoma patients with dabrafenib and trametinib-induced pyrexia
H. Kim, J. Duong, Maria Gonzalez, G. Long +5 more
2019Cancer Chemotherapy and Pharmacology22 citations
Semantic Scholar
Role of UDP-Glucuronosyltransferase Isoforms in 13-cis Retinoic Acid Metabolism in Humans
Sophie E Rowbotham, Nicola A. Illingworth, A. Daly, G. Veal +1 more
2010Drug Metabolism And Disposition22 citations
Semantic Scholar
Pharmacokinetics of cyclophosphamide and its metabolites in paediatric patients receiving high-dose myeloablative therapy.
G. Chinnaswamy, J. Errington, A. Foot, A. Boddy +2 more
2011European Journal of Cancer21 citations
Semantic Scholar
Bioactive Compounds and Cancer
A. Boddy
201121 citations Open access
Semantic Scholar
Audit of Data Sharing by Pharmaceutical Companies for Anticancer Medicines Approved by the US Food and Drug Administration
Natansh D. Modi, A. Abuhelwa, R. Mckinnon, A. Boddy +7 more
2022JAMA Oncology19 citations Open access
Semantic Scholar
Physiologically-Based Pharmacokinetic Predictions of the Effect of Curcumin on Metabolism of Imatinib and Bosutinib: In Vitro and In Vivo Disconnect
Jeffry Adiwidjaja, A. Boddy, A. McLachlan
2020Pharmaceutical Research19 citations
Semantic Scholar
Potential for pharmacokinetic interactions between Schisandra sphenanthera and bosutinib, but not imatinib: in vitro metabolism study combined with a physiologically‐based pharmacokinetic modelling approach
Jeffry Adiwidjaja, A. Boddy, A. McLachlan
2020British Journal of Clinical Pharmacology18 citations Open access
Semantic Scholar
Genetic variants in the HER2 gene: Influence on HER2 overexpression and loss of heterozygosity in breast cancer.
N. Cresti, J. Lee, E. Rourke, D. Televantou +3 more
2016European Journal of Cancer17 citations
Semantic Scholar
Pharmacokinetics of carboplatin and etoposide in infant neuroblastoma patients
G. Veal, M. Cole, J. Errington, A. Pearson +4 more
2010Cancer Chemotherapy and Pharmacology17 citations Open access
Semantic Scholar
Minimization of the Preanalytical Error in Plasma Samples for Pharmacokinetic Analyses and Therapeutic Drug Monitoring - Using Doxorubicin as an Example
Nina E. Kontny, G. Hempel, J. Boos, A. Boddy +1 more
2011Therapeutic Drug Monitoring16 citations Open access
Semantic Scholar
Physiologically‐based pharmacokinetic model predictions of inter‐ethnic differences in imatinib pharmacokinetics and dosing regimens
Jeffry Adiwidjaja, A. S. Gross, A. Boddy, A. McLachlan
2021British Journal of Clinical Pharmacology15 citations
Semantic Scholar
A phase I pharmacokinetic and pharmacodynamic study of the oral mitogen-activated protein kinase kinase (MEK) inhibitor, WX-554, in patients with advanced solid tumours.
D. Jamieson, M. Griffin, J. Sludden, Y. Drew +18 more
2016European Journal of Cancer14 citations Open access
Semantic Scholar
Calpain‐1 is associated with adverse relapse free survival in breast cancer: a confirmatory study
Xuan Pu, S. Storr, Narmeen S. Ahmad, S. Chan +6 more
2016Histopathology13 citations Open access
Semantic Scholar
Physiologically based pharmacokinetic model predictions of natural product-drug interactions between goldenseal, berberine, imatinib and bosutinib
Jeffry Adiwidjaja, A. Boddy, A. McLachlan
2022European Journal of Clinical Pharmacology12 citations
Semantic Scholar
Genetic Polymorphisms Affecting Cardiac Biomarker Concentrations in Children with Cancer: an Analysis from the “European Paediatric Oncology Off-patents Medicines Consortium” (EPOC) Trial
Farina Hellmann, S. Völler, M. Krischke, D. Jamieson +4 more
2020European journal of drug metabolism and pharmacokinetics12 citations Open access
Semantic Scholar
Investigating the potential impact of dose banding for systemic anti-cancer therapy in the paediatric setting based on pharmacokinetic evidence
M. White-Koning, C. Osborne, A. Paci, A. Boddy +2 more
2018European Journal of Cancer12 citations Open access
Semantic Scholar
Wnt receptor gene FZD1 was associated with schizophrenia in genome-wide SNP analysis of the Australian Schizophrenia Research Bank cohort
Xiaoman Liu, Siew-Kee Low, J. Atkins, J. Wu +16 more
2019Australian and New Zealand journal of psychiatry (Print)11 citations
Semantic Scholar
Population pharmacokinetics of carboplatin, etoposide and melphalan in children: a re‐evaluation of paediatric dosing formulas for carboplatin in patients with normal or mild impairment of renal function
J. Duong, G. Veal, C. Nath, P. Shaw +3 more
2018British Journal of Clinical Pharmacology10 citations Open access
Semantic Scholar

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