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C. Nath · SciRah

Researcher profile · Semantic Scholar

C. Nath

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C. Nath — researcher profile on SciRah

h-index: 21
Works: 68
Citations: 1,477

Most-cited papers

A New Harmonized Approach to Estimate Busulfan Exposure Predicts Survival and Toxicity after Hematopoietic Cell Transplantation in Children and Young Adults: a Multicenter Retrospective Cohort Analysis
I. Bartelink, A. Lalmohamed, E. V. van Reij, C. Dvorak +28 more
2016The Lancet Haematology248 citations Open access
Semantic Scholar
Body Weight-Dependent Pharmacokinetics of Busulfan in Paediatric Haematopoietic Stem Cell Transplantation Patients
I. Bartelink, J. Boelens, R. Bredius, A. Egberts +8 more
2012Clinical Pharmacokinetics115 citations
Semantic Scholar
Population Pharmacokinetics of Liposomal Amphotericin B in Pediatric Patients with Malignant Diseases
Ying Hong, P. Shaw, C. Nath, S. Yadav +3 more
2006Antimicrobial Agents and Chemotherapy96 citations Open access
Semantic Scholar
Population pharmacokinetics of melphalan in patients with multiple myeloma undergoing high dose therapy.
C. Nath, Peter Shaw, J. Trotman, L. Zeng +10 more
2010British Journal of Clinical Pharmacology75 citations Open access
Semantic Scholar
Body weight-dependent pharmacokinetics of busulfan in pediatric hematopoietic stem cell transplantation patients: towards individualized dosing
I. Bartelink, J. J. Boelens, R. Bredius, A. Egberts +8 more
201368 citations
Semantic Scholar
High melphalan exposure is associated with improved overall survival in myeloma patients receiving high dose melphalan and autologous transplantation.
C. Nath, J. Trotman, C. Tiley, P. Presgrave +9 more
2016British Journal of Clinical Pharmacology57 citations Open access
Semantic Scholar
Pre-existing antibodies against polyethylene glycol reduce asparaginase activities on first administration of pegylated E. coli asparaginase in children with acute lymphocytic leukemia
Al-Sheikh Khalil, G. Würthwein, Jana Golitsch, G. Hempel +15 more
2020Haematologica53 citations Open access
Semantic Scholar
Not too little, not too much—just right! (Better ways to give high dose melphalan)
Peter Shaw, C. Nath, H. Lazarus
2014Bone Marrow Transplantation51 citations Open access
Semantic Scholar
Busulphan in blood and marrow transplantation: dose, route, frequency and role of therapeutic drug monitoring.
C. Nath, P. Shaw
2007Current Clinical Pharmacology48 citations
Semantic Scholar
Amphotericin B in Children with Malignant Disease: a Comparison of the Toxicities and Pharmacokinetics of Amphotericin B Administered in Dextrose versus Lipid Emulsion
C. Nath, P. Shaw, Robyn Gunning, A. McLachlan +1 more
1999Antimicrobial Agents and Chemotherapy45 citations Open access
Semantic Scholar
Variability in the pharmacokinetics of intravenous busulphan given as a single daily dose to paediatric blood or marrow transplant recipients.
C. Nath, J. Earl, N. Pati, K. Stephen +1 more
2008British Journal of Clinical Pharmacology44 citations Open access
Semantic Scholar
Population pharmacokinetics of amphotericin B in children with malignant diseases.
C. Nath, A. McLachlan, Peter Shaw, Robyn Gunning +1 more
2001British Journal of Clinical Pharmacology40 citations Open access
Semantic Scholar
Association between the magnitude of intravenous busulfan exposure and development of hepatic veno-occlusive disease in children and young adults undergoing myeloablative allogeneic hematopoietic cell transplantation.
T. Bognàr, I. Bartelink, T. Egberts, C. Rademaker +25 more
2022Transplantation and Cellular Therapy39 citations Open access
Semantic Scholar
Population pharmacokinetics of melphalan in paediatric blood or marrow transplant recipients.
C. Nath, P. Shaw, Kay Montgomery, J. Earl
2007British Journal of Clinical Pharmacology35 citations Open access
Semantic Scholar
Population pharmacokinetics of mycophenolic acid in children and young people undergoing blood or marrow and solid organ transplantation.
L. Zeng, E. Y. L. Blair, C. Nath, P. Shaw +7 more
2010British Journal of Clinical Pharmacology31 citations Open access
Semantic Scholar
Increasing the dosage of vincristine
S. Kellie, P. Koopmans, J. Earl, C. Nath +3 more
2004Cancer28 citations Open access
Semantic Scholar
Melphalan pharmacokinetics in children with malignant disease: influence of body weight, renal function, carboplatin therapy and total body irradiation.
C. Nath, P. Shaw, Kay Montgomery, J. Earl
2005British Journal of Clinical Pharmacology26 citations Open access
Semantic Scholar
Population Pharmacokinetics of Acyclovir in Children and Young People with Malignancy after Administration of Intravenous Acyclovir or Oral Valacyclovir
L. Zeng, C. Nath, E. Y. L. Blair, P. Shaw +4 more
2009Antimicrobial Agents and Chemotherapy25 citations Open access
Semantic Scholar
Precision dosing of intravenous busulfan in pediatric hematopoietic stem cell transplantation: Results from a multicenter population pharmacokinetic study
Khalil Ben Hassine, T. Nava, Y. Théorêt, C. Nath +9 more
2021CPT: Pharmacometrics & Systems Pharmacology23 citations Open access
Semantic Scholar
An isocratic fluorescence HPLC assay for the monitoring of l-asparaginase activity and l-asparagine depletion in children receiving E. colil-asparaginase for the treatment of acute lymphoblastic leukaemia.
C. Nath, Luciano Dallapozza, A. Eslick, A. Misra +2 more
2009Biomedical chromotography23 citations
Semantic Scholar
HPLC-UV assay for monitoring total and unbound mycophenolic acid concentrations in children.
L. Zeng, C. Nath, Peter Shaw, J. Earl +1 more
2009Biomedical chromotography23 citations
Semantic Scholar
Fetal Oxygen Saturation Monitoring in Labour: An Analysis of 118 Cases
Christine East, Kimble R. Dunster, P. Colditz, C. Nath +1 more
1997Australian and New Zealand journal of obstetrics and gynaecology22 citations
Semantic Scholar
Plasma protein distribution and its impact on pharmacokinetics of liposomal amphotericin B in paediatric patients with malignant diseases
Ying Hong, P. Shaw, Bruce N. Tattam, C. Nath +3 more
2007European Journal of Clinical Pharmacology21 citations
Semantic Scholar
Busulphan given as four single daily doses of 150 mg/m2 is safe and effective in children of all ages
Peter Shaw, C. Nath, A. Berry, J. Earl
2004Bone Marrow Transplantation20 citations
Semantic Scholar
Association of busulfan exposure and outcomes after HCT for patients with an inborn error of immunity
T. Bognàr, Moises Garcia-Rosa, A. Lalmohamed, T. Gungor +34 more
2024Blood Advances19 citations Open access
Semantic Scholar
Therapeutic Drug Monitoring of Asparaginase Activity—Method Comparison of MAAT and AHA Test Used in the International AIEOP-BFM ALL 2009 Trial
C. Lanvers-Kaminsky, A. Rüffer, G. Würthwein, J. Gerss +12 more
2017Therapeutic Drug Monitoring19 citations
Semantic Scholar
HPLC-fluorescence assay for acyclovir in children.
L. Zeng, C. Nath, P. Shaw, J. Earl +1 more
2008Biomedical chromotography19 citations
Semantic Scholar
An HPLC–PDA method for determination of alectinib concentrations in the plasma of an adolescent
Samiuela Lee, C. Nath, Ben W R Balzer, C. Lewis +3 more
2020Acta Chromatographica15 citations Open access
Semantic Scholar
Amphotericin B Dose Optimization in Children with Malignant Diseases
C. Nath, A. McLachlan, P. Shaw, J. Coakley +1 more
2007Chemotherapy13 citations
Semantic Scholar
Development and Validation of a High Pressure Liquid Chromatography-UV Method for the Determination of Treosulfan and Its Epoxy Metabolites in Human Plasma and Its Application in Pharmacokinetic Studies.
S. Koyyalamudi, U. Kuzhiumparambil, C. Nath, J. Byrne +4 more
2015Journal of Chromatographic Science12 citations
Semantic Scholar
Interpretation of alpha-fetoprotein concentrations in cerebrospinal fluid of infants
J. Coakley, S. Kellie, C. Nath, A. Munas +1 more
2005Annals of Clinical Biochemistry12 citations Open access
Semantic Scholar
Impact of Antibodies Against Polyethylene Glycol on the Pharmacokinetics of PEGylated Asparaginase in Children with Acute Lymphoblastic Leukaemia: A Population Pharmacokinetic Approach
Christian Siebel, C. Lanvers-Kaminsky, J. Alten, P. Smisek +4 more
2021European journal of drug metabolism and pharmacokinetics10 citations Open access
Semantic Scholar
Population pharmacokinetics of carboplatin, etoposide and melphalan in children: a re‐evaluation of paediatric dosing formulas for carboplatin in patients with normal or mild impairment of renal function
J. Duong, G. Veal, C. Nath, P. Shaw +3 more
2018British Journal of Clinical Pharmacology10 citations Open access
Semantic Scholar
The impact of age and renal function on the pharmacokinetics and protein binding characteristics of fludarabine in paediatric and adult patients undergoing allogeneic haematopoietic stem cell transplantation conditioning
C. Nath, Sebastian P. A. Rosser, Kiran K Nath, Jason Chung +5 more
2024European Journal of Clinical Pharmacology9 citations Open access
Semantic Scholar
Pharmacokinetics of cyclosporin in children with stable renal transplants
J. Tam, J. Earl, N. Willis, Jill E. Farquhar +3 more
2000Pediatric nephrology (Berlin, West)9 citations
Semantic Scholar
Evaluation of treosulfan cumulative exposure in paediatric patients through population pharmacokinetics and dosing simulations
Sebastian P. A. Rosser, Samiuela Lee, Shruti Kohli, S. Keogh +6 more
2022British Journal of Clinical Pharmacology6 citations Open access
Semantic Scholar
Quantification of vincristine and tariquidar by LC-MS/MS in mouse whole blood using volumetric absorptive microsampling for pharmacokinetic applications.
Sebastian P. A. Rosser, C. Atkinson, C. Nath, J. Fletcher
2022Journal of Separation Science6 citations
Semantic Scholar
Therapeutic drug monitoring of asparaginase: intra-individual variability and predictivity in children with acute lymphoblastic leukemia treated with PEG-asparaginase in the AIEOP-BFM ALL 2009 study.
G. Würthwein, C. Lanvers-Kaminsky, J. Gerss, A. Möricke +9 more
2020Therapeutic Drug Monitoring6 citations
Semantic Scholar
Falsely low vancomycin results using the Abbott TDx
F. Wood, J. Earl, C. Nath, J. Coakley
2000Annals of Clinical Biochemistry6 citations
Semantic Scholar
Alectinib is effective, safe and tolerable in an adolescent with stage IVB ALK-rearranged adenocarcinoma of the lung
Ben W R Balzer, C. Loo, E. Wegner, C. Nath +5 more
2018Pediatric Hematology & Oncology5 citations Open access
Semantic Scholar
The pharmacokinetics and pharmacodynamics of busulfan when combined with melphalan as conditioning in adult autologous stem cell transplant recipients
A. Willcox, E. Wong, C. Nath, B. Janson +6 more
2018Annals of Hematology5 citations
Semantic Scholar
Studying the Optimal Intravenous Busulfan Exposure in Pediatric Allogeneic Hematopoietic Cell Transplantation (alloHCT) to Improve Clinical Outcomes: A Multicenter Study
A. Lalmohamed, I. Bartelink, L. van Reij, C. Dvorak +19 more
20155 citations Open access
Semantic Scholar
Higher Melphalan Exposure Is Associated with Improved Overall Survival for Myeloma Patients Undergoing Autologous Transplant
P. Shaw, C. Nath, I. Nivison-Smith, D. Joshua +5 more
20125 citations Open access
Semantic Scholar
ATRA administration in the critically ill patient.
P. Shaw, M. Atkins, C. Nath, J. Earl
1995Leukemia5 citations
Semantic Scholar
Validation of a liquid chromatography-tandem mass spectrometry method for simultaneous quantification of N,N-dimethylacetamide and N-monomethylacetamide in paediatric plasma.
Sebastian P. A. Rosser, A. McLachlan, G. Hempel, J. Chung +3 more
2023Journal of Separation Science4 citations Open access
Semantic Scholar
Melphalan exposure and outcome in obese and non-obese adults with myeloma. A study of pharmacokinetics and pharmacodynamics
C. Nath, J. Trotman, I. Nivison-Smith, H. Gurney +7 more
2020Bone Marrow Transplantation3 citations
Semantic Scholar
A New Harmonized Approach to Estimate Busulfan Exposure Predicts Survival and Toxicity after Hematopoietic Cell Transplantation in Children and Young Adults : a Multicenter Retrospective Cohort Analysis
I. Bartelink, A. Lalmohamed, E. V. van Reij, C. Dvorak +30 more
20173 citations
Semantic Scholar
Evaluation of Pharmacokinetic-Based Dose Predictions of High Dose Melphalan in Patients with Myeloma
J. Trotman, P. Shaw, C. Tiley, S. Ramanathan +6 more
20153 citations
Semantic Scholar
Outcomes from hematopoietic stem cell transplantation following treosulfan‐based conditioning: A clinical and pharmacokinetic analysis
Sebastian P. A. Rosser, Alice Brewer, Melissa Gabriel, Melanie Wong +5 more
2024Pediatric Transplantation2 citations
Semantic Scholar
Association study of candidate DNA-repair gene variants and acute graft versus host disease in pediatric patients receiving allogeneic hematopoietic stem-cell transplantation
C. Uppugunduri, P. H. Curtis, T. Nava, M. A. Rezgui +18 more
2021The Pharmacogenomics Journal2 citations Open access
Semantic Scholar

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