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Hua Fang · SciRah

Researcher profile · Semantic Scholar

Hua Fang

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Hua Fang — researcher profile on SciRah

h-index: 18
Works: 34
Citations: 1,455

Most-cited papers

VISTA is an acidic pH-selective ligand for PSGL-1
R. Johnston, L. Su, Jason Pinckney, D. Critton +32 more
2019Nature371 citations
Semantic Scholar
Biochemical and Genetic Characterizations of a Novel Human Immunodeficiency Virus Type 1 Inhibitor That Blocks gp120-CD4 Interactions
Qi Guo, H. Ho, I. Dicker, L. Fan +13 more
2003Journal of Virology170 citations Open access
Semantic Scholar
Development and Validation of a Rapid, Single-Step Reverse Transcriptase Loop-Mediated Isothermal Amplification (RT-LAMP) System Potentially to Be Used for Reliable and High-Throughput Screening of COVID-19
Ming-Hua Jiang, W. Pan, Amir Arasthfer, W. Fang +8 more
2020Frontiers in Cellular and Infection Microbiology138 citations Open access
Semantic Scholar
Envelope Conformational Changes Induced by Human Immunodeficiency Virus Type 1 Attachment Inhibitors Prevent CD4 Binding and Downstream Entry Events
H. Ho, L. Fan, B. Nowicka-Sans, Brian Mcauliffe +16 more
2006Journal of Virology106 citations Open access
Semantic Scholar
Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 5. An evolution from indole to azaindoles leading to the discovery of 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a drug candidate that demonstrates antiviral activity
Tao Wang, Z. Yin, Z. Zhang, J. A. Bender +22 more
2009Journal of Medicinal Chemistry94 citations Open access
Semantic Scholar
Genotypic correlates of susceptibility to HIV-1 attachment inhibitor BMS-626529, the active agent of the prodrug BMS-663068.
N. Zhou, B. Nowicka-Sans, Brian Mcauliffe, N. Ray +9 more
2014Journal of Antimicrobial Chemotherapy71 citations Open access
Semantic Scholar
In Vivo Efficacy of Anti-Glycoprotein 41, But Not Anti-Glycoprotein 120, Immunotoxins in a Mouse Model of HIV Infection 1
S. Pincus, Hua Fang, R. Wilkinson, Tamera K. Marcotte +2 more
2003Journal of Immunology56 citations Open access
Semantic Scholar
In Vivo Patterns of Resistance to the HIV Attachment Inhibitor BMS-488043
N. Zhou, B. Nowicka-Sans, Sharon Zhang, L. Fan +13 more
2010Antimicrobial Agents and Chemotherapy54 citations Open access
Semantic Scholar
Evolving Molecular Epidemiological Profile of Human Immunodeficiency Virus 1 in the Southwest Border of China
Ying-yu Chen, Song Chen, Jun Kang, Hua Fang +8 more
2014PLoS ONE36 citations Open access
Semantic Scholar
Humoral and cellular immunity to Plasmodium falciparum merozoite surface protein 1 and protection from infection with blood-stage parasites.
A. Moormann, P. Sumba, K. Chelimo, Hua Fang +6 more
2013Journal of Infectious Diseases36 citations Open access
Semantic Scholar
HCV NS5A replication complex inhibitors. Part 4. Optimization for genotype 1a replicon inhibitory activity.
D. S. St. Laurent, M. Serrano-Wu, M. Belema, Min Ding +19 more
2014Journal of Medicinal Chemistry33 citations
Semantic Scholar
In Vitro Effects of Anti-HIV Immunotoxins Directed against Multiple Epitopes on HIV Type 1 Envelope Glycoprotein 160
Seth H. Pincus, K. Wehrly, Robert L. Cole, Hua Fang +12 more
1996AIDS Research and Human Retroviruses32 citations
Semantic Scholar
Hepatitis C virus NS5A replication complex inhibitors. Part 6: Discovery of a novel and highly potent biarylimidazole chemotype with inhibitory activity toward genotypes 1a and 1b replicons.
M. Belema, V. Nguyen, J. Romine, D. S. St. Laurent +15 more
2014Journal of Medicinal Chemistry28 citations
Semantic Scholar
Discovery of a Potent Acyclic, Tripeptidic, Acyl Sulfonamide Inhibitor of Hepatitis C Virus NS3 Protease as a Back-up to Asunaprevir with the Potential for Once-Daily Dosing.
Li-Qiang Sun, E. Mull, B. Zheng, S. D'Andrea +52 more
2016Journal of Medicinal Chemistry24 citations Open access
Semantic Scholar
Molecular Tracing of Sexual HIV Type 1 Transmission in the Southwest Border of China
L. Bao, N. Vidal, Hua Fang, Wei Deng +7 more
2008AIDS Research and Human Retroviruses24 citations
Semantic Scholar
Suppression of HIV Replication by CD8+ Regulatory T-Cells in Elite Controllers
Wei Lu, Song Chen, Chun-Hui Lai, Mingyue Lai +7 more
2016Frontiers in Immunology23 citations Open access
Semantic Scholar
Influence of endosome-destabilizing peptides on efficacy of anti-HIV immunotoxins.
Vladimir V. Tolstikov, Robert L. Cole, Hua Fang, S. Pincus
1997Bioconjugate chemistry23 citations
Semantic Scholar
Improving Metabolic Stability with Deuterium: The Discovery of BMT-052, a Pan-genotypic HCV NS5B Polymerase Inhibitor.
Kyle Parcella, K. Eastman, Kap-Sun Yeung, Katharine A Grant-Young +21 more
2017ACS Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Increased sensitivity of HIV variants selected by attachment inhibitors to broadly neutralizing antibodies.
N. Zhou, L. Fan, H. Ho, B. Nowicka-Sans +12 more
2010Virology18 citations Open access
Semantic Scholar
Discovery of BMS-986144, a Third-Generation, Pan-Genotype NS3/4A Protease Inhibitor for the Treatment of Hepatitis C Virus Infection.
Li-Qiang Sun, E. Mull, S. D'Andrea, B. Zheng +33 more
2020Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
In vivo testing of anti-HIV immunotoxins.
Seth H. Pincus, Tamera K. Marcotte, Brent M. Forsyth, Hua Fang
2001Methods in molecular biology17 citations
Semantic Scholar
The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase.
K. Eastman, Kyle Parcella, Kap-Sun Yeung, Katharine A Grant-Young +27 more
2017MedChemComm14 citations Open access
Semantic Scholar
Unique insertion sequence and pattern of CD4 expression in variants selected with immunotoxins from human immunodeficiency virus type 1-infected T cells
Hua Fang, Seth H. Pincus
1995Journal of Virology12 citations Open access
Semantic Scholar
Protection against HIV-envelope-induced neuronal cell destruction by HIV attachment inhibitors
Sharon Zhang, L. Alexander, Tao Wang, M. Agler +5 more
2010Archives of Virology9 citations
Semantic Scholar
Processing of the envelope glycoprotein gp160 in immunotoxin-resistant cell lines chronically infected with human immunodeficiency virus type 1
Thomas D. Duensing, Hua Fang, David W. Dorward, Seth H. Pincus
1995Journal of Virology8 citations Open access
Semantic Scholar
Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase.
B. Zheng, S. D'Andrea, U. Hanumegowda, J. Knipe +18 more
2017Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
A Modified SCID Mouse Model of HIV Infection with Utility for Testing Anti-HIV Therapies
S. Pincus, Hua Fang, R. Wilkinson, W. Olson +1 more
2003AIDS Research and Human Retroviruses6 citations
Semantic Scholar
Use of Anti-HIV Immunotoxins as Probes of the Biology of HIV-Infected Cells
S. Pincus, J. Mcclure, Hua Fang
19945 citations Open access
Semantic Scholar
Spontaneous Activation of Human Immunodeficiency Virus Type 1 in an Immunotoxin-Resistant Variant T Cell Line
Hua Fang, Seth H. Pincus
1999AIDS Research and Human Retroviruses3 citations
Semantic Scholar
Structure-Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors.
Kap-Sun Yeung, Brett R. Beno, Kathy Mosure, Juliang Zhu +23 more
2018ACS Medicinal Chemistry Letters2 citations Open access
Semantic Scholar
Functionalized triazines as potent HCV entry inhibitors.
E. Mull, Li-Qiang Sun, Qian Zhao, Betsy J. Eggers +12 more
2017Bioorganic & Medicinal Chemistry Letters2 citations
Semantic Scholar
The results analysis of HIV antibody detection in different groups in Xishuangbanna in 2010
Jian-B. Shen, H. Dao, Jun Kang, Hua Fang +4 more
20110 citations
Semantic Scholar
a Mouse Model of HIV Infection Not Anti-Glycoprotein 120 , Immunotoxins in In Vivo Efficacy of Anti-Glycoprotein 41
S. Pincus, Hua Fang, R. Wilkinson, Tamera K. Marcotte +2 more
20030 citations
Semantic Scholar
Anti-HIV Immunotoxins
S. Pincus, Hua Fang, R. Wilkinson
20020 citations
Semantic Scholar

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