Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

N. Vázquez-Laslop · SciRah

Researcher profile · Semantic Scholar

N. Vázquez-Laslop

Share profile

N. Vázquez-Laslop — researcher profile on SciRah

h-index: 39
Works: 104
Citations: 5,027

Most-cited papers

How macrolide antibiotics work
N. Vázquez-Laslop, A. Mankin
2018TIBS -Trends in Biochemical Sciences. Regular ed357 citations Open access
Semantic Scholar
Molecular mechanism of drug-dependent ribosome stalling.
N. Vázquez-Laslop, C.H. Thum, A. Mankin
2008Molecules and Cells273 citations Open access
Semantic Scholar
Increased Persistence in Escherichia coli Caused by Controlled Expression of Toxins or Other Unrelated Proteins
N. Vázquez-Laslop, Hyunwoo Lee, A. A. Neyfakh
2006Journal of Bacteriology244 citations
Semantic Scholar
A protein that activates expression of a multidrug efflux transporter upon binding the transporter substrates.
Maqbool Ahmed, C. Borsch, S. Taylor, N. Vázquez-Laslop +1 more
1994Journal of Biological Chemistry215 citations Open access
Semantic Scholar
Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated
Maqbool Ahmed, L. Lyass, P. Markham, S. Taylor +2 more
1995Journal of Bacteriology190 citations Open access
Semantic Scholar
An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome
T. Florin, C. Maracci, M. Graf, Prajwal Karki +7 more
2017Nature Structural &Molecular Biology170 citations Open access
Semantic Scholar
Programmed drug‐dependent ribosome stalling
H. Ramu, A. Mankin, N. Vázquez-Laslop
2009Molecular Microbiology166 citations Open access
Semantic Scholar
Retapamulin-assisted ribosome profiling reveals the alternative bacterial proteome
Sezen Meydan, J. Marks, D. Klepacki, Virag Sharma +6 more
2019bioRxiv162 citations Open access
Semantic Scholar
The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide
N. Vázquez-Laslop, H. Ramu, D. Klepacki, K. Kannan +1 more
2010EMBO Journal157 citations Open access
Semantic Scholar
Selective protein synthesis by ribosomes with a drug-obstructed exit tunnel.
K. Kannan, N. Vázquez-Laslop, A. Mankin
2012Cell154 citations Open access
Semantic Scholar
Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center
J. Marks, K. Kannan, E. Roncase, D. Klepacki +4 more
2016Proceedings of the National Academy of Sciences of the United States of America153 citations Open access
Semantic Scholar
Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center.
H. Ramu, N. Vázquez-Laslop, D. Klepacki, Qing Dai +3 more
2011Molecules and Cells143 citations Open access
Semantic Scholar
Molecular basis for erythromycin-dependent ribosome-stalling during translation of the ErmBL leader peptide
S. Arenz, H. Ramu, Pulkit Gupta, O. Berninghausen +4 more
2014Nature Communications142 citations Open access
Semantic Scholar
Drug-Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation
S. Arenz, Sezen Meydan, A. Starosta, O. Berninghausen +3 more
2014Molecules and Cells119 citations Open access
Semantic Scholar
Molecular Sieve Mechanism of Selective Release of Cytoplasmic Proteins by Osmotically Shocked Escherichia coli
N. Vázquez-Laslop, Hyunwoo Lee, Rong Hu, A. A. Neyfakh
2001Journal of Bacteriology118 citations Open access
Semantic Scholar
Efflux of the Natural Polyamine Spermidine Facilitated by the Bacillus subtilis Multidrug Transporter Blt*
D. Woolridge, N. Vázquez-Laslop, P. Markham, M. Chevalier +2 more
1997Journal of Biological Chemistry108 citations Open access
Semantic Scholar
Macrolide antibiotics allosterically predispose the ribosome for translation arrest
Shanmugapriya Sothiselvam, Bo Liu, Wei Han, H. Ramu +8 more
2014Proceedings of the National Academy of Sciences of the United States of America107 citations Open access
Semantic Scholar
Programmed ribosomal frameshifting generates a copper transporter and a copper chaperone from the same gene
Sezen Meydan, D. Klepacki, S. Karthikeyan, T. Margus +7 more
2017Molecules and Cells95 citations Open access
Semantic Scholar
A BROAD SPECTRUM LASSO PEPTIDE ANTIBIOTIC TARGETING THE BACTERIAL RIBOSOME
Manoj Jangra, Dmitrii Y. Travin, Elena V. Aleksandrova, Manpreet Kaur +11 more
2025Nature87 citations Open access
Semantic Scholar
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics
B. Beckert, Elodie C. Leroy, Shanmugapriya Sothiselvam, L. Bock +10 more
2021Nature Communications78 citations Open access
Semantic Scholar
Deregulation of translation due to post-transcriptional modification of rRNA explains why erm genes are inducible
Pulkit Gupta, Shanmugapriya Sothiselvam, N. Vázquez-Laslop, A. Mankin
2013Nature Communications76 citations Open access
Semantic Scholar
Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol
E. A. Syroegin, Laurin Flemmich, D. Klepacki, N. Vázquez-Laslop +2 more
2022Nature Structural & Molecular Biology74 citations Open access
Semantic Scholar
Regulation of gene expression by macrolide-induced ribosomal frameshifting
Pulkit Gupta, K. Kannan, A. Mankin, N. Vázquez-Laslop
2013Molecules and Cells71 citations Open access
Semantic Scholar
Context specific action of ribosomal antibiotics
N. Vázquez-Laslop, A. Mankin
2017Annual Review of Microbiology68 citations Open access
Semantic Scholar
Role of antibiotic ligand in nascent peptide-dependent ribosome stalling
N. Vázquez-Laslop, D. Klepacki, Debbie C. Mulhearn, H. Ramu +3 more
2011Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
Kinetics of drug–ribosome interactions defines the cidality of macrolide antibiotics
M. Svetlov, N. Vázquez-Laslop, A. Mankin
2017Proceedings of the National Academy of Sciences of the United States of America67 citations Open access
Semantic Scholar
Identifying the targets of aminoacyl-tRNA synthetase inhibitors by primer extension inhibition
C. Orelle, Teresa Szal, D. Klepacki, K. Shaw +2 more
2013Nucleic Acids Research62 citations Open access
Semantic Scholar
Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics
K. Tsai, V. Stojković, D. J. Lee, I. Young +6 more
2022Nature Structural & Molecular Biology56 citations Open access
Semantic Scholar
Dynamics of the context-specific translation arrest by chloramphenicol and linezolid
Junhong Choi, J. Marks, Jingji Zhang, Dong-Hua Chen +4 more
2019Nature Chemical Biology56 citations Open access
Semantic Scholar
Negamycin interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA
Y. Polikanov, Teresa Szal, Fuyan Jiang, Pulkit Gupta +5 more
2014Molecules and Cells55 citations Open access
Semantic Scholar
A fully orthogonal system for protein synthesis in bacterial cells
N. Aleksashin, Teresa Szal, Anne E. D’Aquino, Michael C. Jewett +2 more
2020Nature Communications54 citations Open access
Semantic Scholar
Mechanism of ligand recognition by BmrR, the multidrug-responding transcriptional regulator: mutational analysis of the ligand-binding site.
N. Vázquez-Laslop, P. Markham, A. A. Neyfakh
1999Biochemistry53 citations
Semantic Scholar
Inhibition of translation termination by the antimicrobial peptide Drosocin
Kyle Mangano, D. Klepacki, Irueosa Ohanmu, Chetana Baliga +7 more
2023Nature Chemical Biology49 citations
Semantic Scholar
Assembly and functionality of the ribosome with tethered subunits
N. Aleksashin, Margus Leppik, A. Hockenberry, D. Klepacki +4 more
2019Nature Communications47 citations Open access
Semantic Scholar
Structural basis for the tryptophan sensitivity of TnaC-mediated ribosome stalling
A. van der Stel, Emily R. Gordon, Arnab Sengupta, Allyson K. Martínez +7 more
2021Nature Communications46 citations Open access
Semantic Scholar
Nascent peptide assists the ribosome in recognizing chemically distinct small molecules
Pulkit Gupta, Bo Liu, D. Klepacki, Vrinda Gupta +3 more
2016Nature Chemical Biology46 citations Open access
Semantic Scholar
Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion*
K. Newberry, J. Huffman, Marshall C. Miller, N. Vázquez-Laslop +2 more
2008Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Identifying Small Open Reading Frames in Prokaryotes with Ribosome Profiling
N. Vázquez-Laslop, C. Sharma, A. Mankin, Allen R. Buskirk
2021Journal of Bacteriology43 citations Open access
Semantic Scholar
Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
Shijie Huang, N. Aleksashin, A. Loveland, D. Klepacki +8 more
2020Nature Communications41 citations Open access
Semantic Scholar
Genome-wide effects of the antimicrobial peptide apidaecin on translation termination in bacteria
Kyle Mangano, T. Florin, Xinhao Shao, D. Klepacki +5 more
2020bioRxiv38 citations Open access
Semantic Scholar
Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins
M. Almutairi, M. Svetlov, Douglas A. Hansen, N. Khabibullina +6 more
2017Nucleic Acids Research38 citations Open access
Semantic Scholar
Binding of macrolide antibiotics leads to ribosomal selection against specific substrates based on their charge and size
Shanmugapriya Sothiselvam, Sandro Neuner, L. Rigger, D. Klepacki +3 more
2016Cell Reports38 citations Open access
Semantic Scholar
The vacuolar ATPase ofNeurospora crassa
B. Bowman, N. Vázquez-Laslop, E. J. Bowman
1992Journal of Bioenergetics and Biomembranes38 citations
Semantic Scholar
Genes within Genes in Bacterial Genomes
Sezen Meydan, N. Vázquez-Laslop, A. Mankin
2018Microbiology spectrum36 citations
Semantic Scholar
Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan
Allyson K. Martínez, Emily R. Gordon, Arnab Sengupta, Nitin H. Shirole +9 more
2013Nucleic Acids Research35 citations Open access
Semantic Scholar
Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides
M. Almutairi, Sung Ryeol Park, S. Rose, Douglas A. Hansen +4 more
2015Proceedings of the National Academy of Sciences of the United States of America34 citations Open access
Semantic Scholar
Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms
Elena V. Aleksandrova, Cong-Xuan Ma, D. Klepacki, Faezeh Alizadeh +4 more
2024Nature Chemical Biology33 citations
Semantic Scholar
Context-specific action of macrolide antibiotics on the eukaryotic ribosome
M. Svetlov, Timm O. Koller, Sezen Meydan, Vaishnavi Shankar +6 more
2021Nature Communications33 citations Open access
Semantic Scholar
Recognition of multiple drugs by a single protein: a trivial solution of an old paradox.
N. Vázquez-Laslop, E. Zheleznova, P. Markham, Richard G. Brennan +1 more
2000Biochemical Society Transactions33 citations
Semantic Scholar
Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR)
G. Loughran, D. Andreev, I. Terenin, O. Namy +35 more
2025Nature Structural & Molecular Biology31 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

A. Mankin×38
Invite
A. Mankin — researcher profile on SciRah
D. Klepacki×23
Invite
D. Klepacki — researcher profile on SciRah
A. A. Neyfakh×6
Invite
A. A. Neyfakh — researcher profile on SciRah
H. Ramu×6
Invite
H. Ramu — researcher profile on SciRah

×6

Invite

Y. Polikanov — researcher profile on SciRah

Invite

D. Wilson — researcher profile on SciRah

Sezen Meydan×5

Invite

Sezen Meydan — researcher profile on SciRah

Pulkit Gupta×5

Invite

Pulkit Gupta — researcher profile on SciRah

Invite

Teresa Szal — researcher profile on SciRah

Invite

P. Markham — researcher profile on SciRah

Invite

K. Kannan — researcher profile on SciRah

Shanmugapriya Sothiselvam×4

Invite

Shanmugapriya Sothiselvam — researcher profile on SciRah