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L. Bock · SciRah

Researcher profile · Semantic Scholar

L. Bock

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L. Bock — researcher profile on SciRah

h-index: 17
Works: 90
Citations: 1,507

Most-cited papers

Structure of the E. coli ribosome–EF-Tu complex at <3 Å resolution by Cs-corrected cryo-EM
N. Fischer, P. Neumann, A. Konevega, L. Bock +3 more
2015Nature356 citations Open access
Semantic Scholar
Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
P. Huter, S. Arenz, L. Bock, M. Graf +14 more
2017Molecules and Cells169 citations Open access
Semantic Scholar
Energy barriers and driving forces in tRNA translocation through the ribosome
L. Bock, C. Blau, G. Schröder, I. Davydov +5 more
2013Nature Structural &Molecular Biology164 citations Open access
Semantic Scholar
A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest
S. Arenz, L. Bock, M. Graf, C. Innis +4 more
2016Nature Communications113 citations Open access
Semantic Scholar
The pathway to GTPase activation of elongation factor SelB on the ribosome
N. Fischer, P. Neumann, L. Bock, C. Maracci +8 more
2016Nature108 citations Open access
Semantic Scholar
Automated cryo-EM structure refinement using correlation-driven molecular dynamics
M. Igaev, Carsten Kutzner, L. Bock, A. Vaiana +1 more
2019eLife84 citations Open access
Semantic Scholar
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics
B. Beckert, Elodie C. Leroy, Shanmugapriya Sothiselvam, L. Bock +10 more
2021Nature Communications78 citations Open access
Semantic Scholar
Structural conservation of antibiotic interaction with ribosomes
Helge Paternoga, C. Crowe-McAuliffe, L. Bock, Timm O. Koller +6 more
2023Nature Structural & Molecular Biology74 citations Open access
Semantic Scholar
Effects of cryo-EM cooling on structural ensembles
L. Bock, H. Grubmüller
2021Nature Communications71 citations Open access
Semantic Scholar
Thermodynamic control of −1 programmed ribosomal frameshifting
L. Bock, Neva Caliskan, Natalia Korniy, F. Peske +2 more
2019Nature Communications43 citations Open access
Semantic Scholar
Active role of elongation factor G in maintaining the mRNA reading frame during translation
Bee-Zen Peng, L. Bock, R. Belardinelli, F. Peske +2 more
2019Science Advances39 citations Open access
Semantic Scholar
Molecular simulations of the ribosome and associated translation factors.
L. Bock, M. Kolář, H. Grubmüller
2017Current Opinion in Structural Biology38 citations Open access
Semantic Scholar
Simulation of Complex Biomolecular Systems: The Ribosome Challenge.
L. Bock, Sara Gabrielli, M. Kolář, H. Grubmüller
2022Annual Review of Biophysics37 citations Open access
Semantic Scholar
Dynamic contact network between ribosomal subunits enables rapid large-scale rotation during spontaneous translocation
L. Bock, C. Blau, A. Vaiana, H. Grubmüller
2015Nucleic Acids Research35 citations Open access
Semantic Scholar
Chemomechanical regulation of SNARE proteins studied with molecular dynamics simulations.
L. Bock, Brian L. Hutchings, H. Grubmüller, D. Woodbury
2010Biophysical Journal24 citations Open access
Semantic Scholar
tRNA Dissociation from EF-Tu after GTP Hydrolysis: Primary Steps and Antibiotic Inhibition
M. Warias, H. Grubmüller, L. Bock
2019Biophysical Journal21 citations Open access
Semantic Scholar
Leptonemella species (Desmodoridae, Stilbonematinae), benthic marine nematodes with ectosymbiotic bacteria, from littoral sand of the North Sea island of Sylt: taxonomy and ecological aspects
F. Riemann, F. Thiermann, L. Bock
2003Helgoland Marine Research19 citations Open access
Semantic Scholar
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match.
L. Bock, M. Igaev, H. Grubmüller
2024Current Opinion in Structural Biology15 citations Open access
Semantic Scholar
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel
M. Kolář, G. Nagy, J. Kunkel, S. Vaiana +2 more
2021bioRxiv10 citations Open access
Semantic Scholar
A proposed mechanism for Vibrio export monitoring polypeptide folding in the ribosome exit tunnel
M. Kolář, G. Nagy, L. Bock, J. Kunkel +2 more
2022Biophysical Journal1 citations Open access
Semantic Scholar
Elongation factor G and bacterial resistance to aminoglycosides
Sara Gabrielli, H. Grubmuller, L. Bock
2022Biophysical Journal1 citations Open access
Semantic Scholar
Effects of cryo-EM Freezing on Structural Ensembles
H. Grubmuller, L. Bock
2021Biophysical Journal1 citations Open access
Semantic Scholar
tRNA dissociation from EF-Tu after GTP hydrolysis and Pi release: primary steps and antibiotic inhibition
M. Warias, H. Grubmüller, L. Bock
2019bioRxiv1 citations Open access
Semantic Scholar
Supplemental Information Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor
S. Arenz, L. Bock, M. Graf, L. Peil +6 more
20171 citations
Semantic Scholar
2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM
N. Fischer, P. Neumann, A. Konevega, L. Bock +3 more
20151 citations
Semantic Scholar
Dynamics and driving forces of macromolecular complexes.
L. Bock
20131 citations
Semantic Scholar
BPS2025 - Rest assured: Programmed translational stalling studied by means of MD simulations
Sara Gabrielli, L. Bock
2025Biophysical Journal0 citations Open access
Semantic Scholar
BPS2025 - Structural dynamics of ribosome-stalling peptides in the ribosomal exit tunnel uncovered by MD simulations
Ole Berendes, Sara Gabrielli, H. Grubmüller, L. Bock
2025Biophysical Journal0 citations Open access
Semantic Scholar
BPS2025 - Applying Bayes to PET-FCS data of cotranslational folding
A. D. de Maeyer, H. Grubmuller, L. Bock
2025Biophysical Journal0 citations Open access
Semantic Scholar
BPS2025 - Integrating single-molecule and ensemble measurements using a Bayesian approach to infer kinetic rates
L. Bock, Sakshi Jain, Panagiotis Poulis, Marina V. Rodnina +1 more
2025Biophysical Journal0 citations Open access
Semantic Scholar
Ribosome stalling in presence and absence of antibiotics studied by MD simulations
L. Bock, Sara Gabrielli, H. Grubmüller
2024Biophysical Journal0 citations
Semantic Scholar
Rest assured: Programmed translational stalling studied by MD simulations
Sara Gabrielli, Martin M. Morici, Keigo Fujiwara, Helge Paternoga +4 more
2024Biophysical Journal0 citations
Semantic Scholar
Effects of cryo-EM cooling on structural ensembles of biomolecules and their solvation shell.
H. Grubmüller, L. Bock
2023Biophysical Journal0 citations Open access
Semantic Scholar
Mechanisms of ribosome stalling and unstalling studied by MD simulations.
L. Bock, H. Grubmüller
2023Biophysical Journal0 citations Open access
Semantic Scholar
Elongation Factor G Mutations and Bacterial Resistance to Aminoglycosides
Sara Gabrielli, L. Bock, H. Grubmueller
20210 citations Open access
Semantic Scholar
Mechanism of the Activation of Ribosome Rescue Factor ArfB
L. Bock
20210 citations Open access
Semantic Scholar
Atomistic Simulations of the Human Proteasome Inhibited by a Covalent Ligand
M. Kolář, L. Bock, H. Grubmüller
2020High Performance Computing in Science and Engineering '200 citations Open access
Semantic Scholar
Kinetics and Thermodynamics of −1 Ribosomal Frameshifting
L. Bock, Neva Caliskan, Bee-Zen Peng, Natalia Korniy +4 more
20200 citations Open access
Semantic Scholar
Automated cryo-EM Structure Refinement using Correlation-Driven Molecular Dynamics
A. Vaiana, M. Igaev, L. Bock, Carsten Kutzner +1 more
2020Biophysical Journal0 citations Open access
Semantic Scholar
Thermodynamic Control of Ribosomal Frameshifting
L. Bock, Neva Caliskan, Natalia Korniy, F. Peske +2 more
2019Biophysical Journal0 citations Open access
Semantic Scholar
Automated cryo-EM structure 1 refinement using correlation-driven 2 molecular dynamics 3
M. Igaev, Carsten Kutzner, L. Bock, A. Vaiana +2 more
20190 citations
Semantic Scholar
The ribosome : a stunningly complex “ nanomachine ”
L. Bock, M. Kolář, A. Vaiana, H. Grubmüller
20180 citations
Semantic Scholar
Effects of cryo-EM freezing on the structural ensemble.
L. Bock, H. Grubmüller
20180 citations Open access
Semantic Scholar
Mechanisms of Sequence Dependent Translational Stalling
L. Bock, P. Huter, S. Arenz, M. Graf +3 more
20170 citations Open access
Semantic Scholar
Dynamics and Energetics of Elongation Factor SelB in the Ternary Complex and the Ribosome
L. Bock, N. Fischer, H. Stark, H. Grubmüller
20170 citations Open access
Semantic Scholar
Plat Torque Generation in the Bacterial Flagellar Motor
R. Berry, G. Oster, Harvey F. Chin, E. Karatekin +10 more
20170 citations
Semantic Scholar
Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA
S. Arenz, L. Bock, M. Graf, C. Innis +4 more
20160 citations
Semantic Scholar
ErmBL translation on the ribosome in the presence of erythromycin is stalled by inhibition of peptide bond formation.
L. Bock, S. Arenz, D. Wilson, H. Grubmüller +1 more
20160 citations Open access
Semantic Scholar
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the codon reading state (CR)
N. Fischer, P. Neumann, L. Bock, C. Maracci +8 more
20160 citations
Semantic Scholar
Structure of SelB-Sec-tRNASec bound to the 70S ribosome in the GTPase activated state (GA)
N. Fischer, P. Neumann, L. Bock, C. Maracci +8 more
20160 citations
Semantic Scholar

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H. Grubmüller×27
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H. Grubmüller — researcher profile on SciRah
M. Rodnina×12
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A. Vaiana×12
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H. Grubmueller×9
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S. Arenz — researcher profile on SciRah

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N. Fischer — researcher profile on SciRah

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H. Stark — researcher profile on SciRah

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M. Graf — researcher profile on SciRah

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Sara Gabrielli×7

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Sara Gabrielli — researcher profile on SciRah

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M. Kolář — researcher profile on SciRah

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P. Neumann — researcher profile on SciRah