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B. Evers · SciRah

Researcher profile · Semantic Scholar

B. Evers

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B. Evers — researcher profile on SciRah

h-index: 27
Works: 42
Citations: 4,599

Most-cited papers

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.
P. Derksen, Xiao-Ling Liu, Francis Saridin, H. van der Gulden +10 more
2006Cancer Cell632 citations Open access
Semantic Scholar
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
H. Gad, T. Koolmeister, A. Jemth, Saeed Eshtad +53 more
2014Nature491 citations
Semantic Scholar
CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes
B. Evers, K. Jastrzebski, J. Heijmans, Wipawadee Grernrum +2 more
2016Nature Biotechnology389 citations
Semantic Scholar
Inducing and exploiting vulnerabilities for the treatment of liver cancer
Cun Wang, S. Vegna, Haojie Jin, Bente Benedict +21 more
2019Nature374 citations Open access
Semantic Scholar
Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin
B. Evers, R. Drost, Eva Schut, M. de Bruin +11 more
2008Clinical Cancer Research333 citations Open access
Semantic Scholar
Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects
B. Evers, Jos Jonkers
2006Oncogene256 citations Open access
Semantic Scholar
High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.
Liqin Wang, Rodrigo Leite de Oliveira, Cun Wang, João M. Fernandes +8 more
2017Cell Reports205 citations Open access
Semantic Scholar
PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.
A. Prahallad, G. Heynen, G. Germano, S. Willems +8 more
2014Cell Reports168 citations Open access
Semantic Scholar
Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis
C. Desmet, T. Gallenne, A. Prieur, F. Reyal +16 more
2013Proceedings of the National Academy of Sciences of the United States of America167 citations Open access
Semantic Scholar
The Deubiquitinase USP28 Stabilizes LSD1 and Confers Stem-cell-like Traits to Breast Cancer Cells
Ya-Di Wu, Yi-Fan Wang, Xiuwei H. Yang, Tie-Bang Kang +4 more
2013Cell Reports167 citations Open access
Semantic Scholar
The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells
M. Barazas, S. Annunziato, S. Pettitt, I. de Krijger +16 more
2018Cell Reports150 citations Open access
Semantic Scholar
Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium.
A. Pietersen, B. Evers, Asheeta A. Prasad, Ellen Tanger +3 more
2008Current Biology137 citations Open access
Semantic Scholar
BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A
J. Puppe, R. Drost, Xiao-Ling Liu, S. Joosse +7 more
2009Breast Cancer Research131 citations Open access
Semantic Scholar
Targeting homologous recombination repair defects in cancer.
B. Evers, T. Helleday, J. Jonkers
2010TIPS - Trends in Pharmacological Sciences116 citations
Semantic Scholar
ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors
K. Berns, Joseph J. Caumanns, E. M. Hijmans, A. Gennissen +10 more
2018Oncogene93 citations Open access
Semantic Scholar
Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer.
Cun Wang, Haojie Jin, Dongmei Gao, C. Lieftink +7 more
2018Journal of Hepatology87 citations Open access
Semantic Scholar
A high throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors
B. Evers, Eva Schut, E. van der Burg, Tanya M. Braumuller +7 more
2009Clinical Cancer Research82 citations Open access
Semantic Scholar
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability
M. E. Geijer, Di Zhou, Kathiresan Selvam, Barbara Steurer +27 more
2021Nature Cell Biology81 citations Open access
Semantic Scholar
The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.
Lenka Oplustil O'Connor, S. Rulten, A. Cranston, R. Odedra +15 more
2016Cancer Research81 citations Open access
Semantic Scholar
A CRISPR screen identifies CDK7 as a therapeutic target in hepatocellular carcinoma
Cun Wang, Haojie Jin, Dongmei Gao, Liqin Wang +7 more
2018Cell Research62 citations Open access
Semantic Scholar
Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance
K. Berns, A. Sonnenblick, A. Gennissen, Sylvain Brohée +20 more
2016Clinical Cancer Research58 citations
Semantic Scholar
DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II
Barbara Steurer, R. C. Janssens, M. E. Geijer, Fernando Aprile-Garcia +9 more
2022Nature Communications56 citations Open access
Semantic Scholar
PC4 promotes genome stability and DNA repair through binding of ssDNA at DNA damage sites
O. Mortusewicz, B. Evers, T. Helleday
2016Oncogene53 citations Open access
Semantic Scholar
Mouse models of BRCA 1 and BRCA 2 deficiency : past lessons , current understanding and future prospects
B. Evers, Link
49 citations
Semantic Scholar
A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair
P. Herr, Cecilia Lundin, B. Evers, D. Ebner +7 more
2015Cell Discovery38 citations Open access
Semantic Scholar
Macrophage p53 controls macrophage death in atherosclerotic lesions of apolipoprotein E deficient mice.
L. Boesten, A. S. M. Zadelaar, A. van Nieuwkoop, Li-Hui Hu +8 more
2009Atherosclerosis31 citations
Semantic Scholar
Selective Inhibition of BRCA 2-Deficient MammaryTumor Cell Growth byAZD 2281 and Cisplatin
B. Evers, R. Drost, Eva Schut, M. de Bruin +11 more
200831 citations
Semantic Scholar
Chronic Low Dose Rate Ionizing Radiation Exposure Induces Premature Senescence in Human Fibroblasts that Correlates with Up Regulation of Proteins Involved in Protection against Oxidative Stress
O. Loseva, E. Shubbar, S. Haghdoost, B. Evers +2 more
2014Proteomes27 citations Open access
Semantic Scholar
Double-strand break toxicity is chromatin context independent
A. Friskes, Lisa Koob, L. Krenning, T. Severson +10 more
2022Nucleic Acids Research26 citations Open access
Semantic Scholar
A tissue reconstitution model to study cancer cell‐intrinsic and ‐extrinsic factors in mammary tumourigenesis
B. Evers, E. Speksnijder, Eva Schut, M. Ciampricotti +4 more
2010Journal of Pathology15 citations Open access
Semantic Scholar
Correction: Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
H. Gad, T. Koolmeister, A. Jemth, Saeed Eshtad +52 more
2017Nature8 citations Open access
Semantic Scholar
Pooled shRNA Screening in Mammalian Cells as a Functional Genomic Discovery Platform.
K. Jastrzebski, B. Evers, R. Beijersbergen
2016Methods in molecular biology4 citations
Semantic Scholar
Phospho-ERK is a response biomarker to a combination of sorafenib and MEK inhibition in liver cancer
Cun Wang, Haojie Jin, Dongmei Gao, B. Evers +6 more
2018bioRxiv3 citations Open access
Semantic Scholar
Abstract 3380: Synthetic lethal interaction betweenARID1Amutation and BET bromodomain inhibition in ovarian clear cell carcinoma
K. Berns, Joseph J. Caumanns, E. M. Hijmans, A. Gennissen +9 more
20172 citations
Semantic Scholar
The Good, the Bad, and the Ugly: in search of gold standards for assessing functional genetic screen quality
B. Evers, R. Bernards, R. Beijersbergen
2014Molecular Systems Biology2 citations Open access
Semantic Scholar
Correction to: Nature Cell Biology https://doi.org/10.1038/s41556-021-00692-z, published online 9 June 2021
M. E. Geijer, Di Zhou, Kathiresan Selvam, Barbara Steurer +27 more
2021Nature Cell Biology1 citations Open access
Semantic Scholar
Conditional mouse models of breast cancer
Xiao-Ling Liu, P. Derksen, B. Evers, H. Holstege +4 more
20051 citations
Semantic Scholar
A fluorescence-based sensor screen identifies MED12 as a potential microsatellite instability regulator in colon cancer
João M. Fernandes, S. Venkatesan, M. Dias, C. Lieftink +8 more
2023bioRxiv0 citations Open access
Semantic Scholar
The PARP inhibitor AZD 2461 is differentiated from olaparib for both PARP 3 activity and drug resistance
L. O'Connor, S. Rulten, A. Cranston, R. Odedra +15 more
20170 citations
Semantic Scholar
Novel compounds with specific toxicity against BRCA2 deficient tumor cells
B. Evers, Santiago Demajo-Meseguer, Eva Schut, B. Rodenko +3 more
20090 citations
Semantic Scholar
Bmi1 regulates stem cells but also proliferation and differentiation of committed cells in mammary gland epithelium
A. Pietersen, B. Evers, Asheeta A. Prasad, Ellen Tanger +4 more
20090 citations
Semantic Scholar
A tissue reconstitution model to assess the contribution of tumor cell-intrinsic and-extrinsic factors in conditional mouse models of breast cancer
B. Evers, E. Speksnijder, Eva Schut, M. Ciampricotti +5 more
20090 citations
Semantic Scholar

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