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Scott N. Furlan · SciRah

Researcher profile · Semantic Scholar

Scott N. Furlan

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Scott N. Furlan — researcher profile on SciRah

h-index: 23
Works: 90
Citations: 2,009

Most-cited papers

Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD
Benjamin K. Watkins, M. Qayed, Courtney Mccracken, Brandi Bratrude +42 more
2021Journal of Clinical Oncology198 citations Open access
Semantic Scholar
Chimeric Antigen Receptor T Cell-Mediated Neurotoxicity in Non-Human Primates
A. Taraseviciute, V. Tkachev, R. Ponce, C. Turtle +19 more
2018Cancer Discovery198 citations Open access
Semantic Scholar
Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression
Steven J. Wu, Scott N. Furlan, Anca B. Mihalas, Hatice S. Kaya-Okur +11 more
2021Nature Biotechnology169 citations Open access
Semantic Scholar
Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: implications for development of immunotherapy
N. Lieberman, Kole R. DeGolier, H. Kovar, Amira Davis +8 more
2018Neuro-Oncology169 citations Open access
Semantic Scholar
A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis.
Megan E. Sheehy, A. McDermott, Scott N. Furlan, P. Klenerman +1 more
2001JIM - Journal of Immunological Methods168 citations
Semantic Scholar
Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.
A. Saha, Roddy S. O'Connor, G. Thangavelu, S. Lovitch +31 more
2016Journal of Clinical Investigation86 citations Open access
Semantic Scholar
HIV-Specific CD8+ T Cell Function in Children with Vertically Acquired HIV-1 Infection Is Critically Influenced by Age and the State of the CD4+ T Cell Compartment1
J. Sandberg, N. Fast, K. Jordan, Scott N. Furlan +7 more
2003Journal of Immunology77 citations
Semantic Scholar
Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia
E. J. Bertrums, Jenny L. Smith, L. Harmon, R. Ries +33 more
2023Haematologica75 citations Open access
Semantic Scholar
Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant
V. Tkachev, Scott N. Furlan, Benjamin K. Watkins, Daniel J. Hunt +14 more
2017Science Translational Medicine74 citations Open access
Semantic Scholar
Transcriptome Analysis of GVHD Reveals Aurora Kinase A as a Targetable Pathway for Disease Prevention
Scott N. Furlan, Benjamin K. Watkins, V. Tkachev, R. Flynn +17 more
2015Science Translational Medicine57 citations Open access
Semantic Scholar
Spatiotemporal single-cell profiling reveals that invasive and tissue-resident donor CD8+ memory T cells drive gastrointestinal acute graft-versus-host disease
V. Tkachev, J. Kaminski, E. L. Potter, Scott N. Furlan +24 more
2021Science Translational Medicine52 citations Open access
Semantic Scholar
Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice.
C. Pennell, J. Barnum, Cameron McDonald-Hyman, A. Panoskaltsis-Mortari +14 more
2018Molecular Therapy51 citations Open access
Semantic Scholar
CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates
Benjamin K. Watkins, V. Tkachev, Scott N. Furlan, Daniel J. Hunt +20 more
2018Journal of Clinical Investigation51 citations Open access
Semantic Scholar
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target
Quy H Le, B. Hadland, Jenny L. Smith, Amanda Leonti +29 more
2022Journal of Clinical Investigation46 citations Open access
Semantic Scholar
Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia
Benjamin J. Huang, Jenny L. Smith, J. Farrar, Yi-Cheng Wang +22 more
2022Nature Communications42 citations Open access
Semantic Scholar
Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells.
Scott N. Furlan, Benjamin K. Watkins, V. Tkachev, S. Cooley +12 more
2016Blood40 citations Open access
Semantic Scholar
IL2 enhances ex-vivo expanded regulatory T cell persistence after adoptive transfer
Scott N. Furlan, Karnail Singh, Christina Lopez, V. Tkachev +6 more
2019bioRxiv38 citations Open access
Semantic Scholar
CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis.
S. Kaliyaperumal, Benjamin K. Watkins, Prachi Sharma, Scott N. Furlan +12 more
2014Blood32 citations Open access
Semantic Scholar
Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity
Simone A. Minnie, Olivia G. Waltner, Kathleen S. Ensbey, Nicole S. Nemychenkov +19 more
2022Science immunology30 citations Open access
Semantic Scholar
Cancer-associated fibroblast-like tumor cells remodel the Ewing sarcoma tumor microenvironment
Emma D. Wrenn, April A. Apfelbaum, E. Rudzinski, Xuemei Deng +12 more
2023Clinical Cancer Research28 citations Open access
Semantic Scholar
NOTCH1 signaling during CD4+ T-cell activation alters transcription factor networks and enhances antigen responsiveness.
Alec B. Wilkens, Elena Fulton, M. Pont, G. Cole +6 more
2022Blood25 citations Open access
Semantic Scholar
CSF1R inhibition promotes neuroinflammation and behavioural deficits during graft-versus-host disease in mice.
Rachael C Adams, Dylan Carter-Cusack, Genesis T Llanes, Christopher R. Hunter +11 more
2023Blood24 citations Open access
Semantic Scholar
Retinoic acid signaling acts as a rheostat to balance Treg function
G. Thangavelu, G. Andrejeva, Sara Bolivar-Wagers, Sujeong Jin +21 more
2022Cellular & Molecular Immunology23 citations Open access
Semantic Scholar
Changes in CD4+ T-Cell Differentiation Phenotype During Structured Treatment Interruption in Patients With Chronic HIV-1 Infection
Thomas Alexander, G. M. Ortiz, M. Wellons, Andrew S. Allen +8 more
2003Journal of Acquired Immune Deficiency Syndromes23 citations Open access
Semantic Scholar
EWS::FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma
April A. Apfelbaum, Feinan Wu, Allegra G. Hawkins, Brian Magnuson +13 more
2022Clinical Cancer Research22 citations Open access
Semantic Scholar
The Knife’s Edge of Tolerance: Inducing Stable Multilineage Mixed Chimerism But With A Significant Risk of CMV Reactivation and Disease in Rhesus Macaques
H. Zheng, Benjamin K. Watkins, V. Tkachev, Shan Yu +15 more
2016American Journal of Transplantation21 citations Open access
Semantic Scholar
Enrichment of activated monocytes in cerebrospinal fluid during antiretroviral therapy
J. Neuenburg, Scott N. Furlan, P. Bacchetti, R. Price +1 more
2005AIDS (London)18 citations Open access
Semantic Scholar
Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation
Lucrezia Colonna, C. Peterson, John B. Schell, Judith M Carlson +35 more
2018Nature Communications17 citations Open access
Semantic Scholar
CD8 T cell effector maturation in HIV-1-infected children.
K. Jordan, Scott N. Furlan, Veronica D. Gonzalez, A. Karlsson +5 more
2006Virology15 citations Open access
Semantic Scholar
Notch signaling drives intestinal graft-versus-host disease in mice and non-human primates
V. Tkachev, A. Vanderbeck, E. Perkey, Scott N. Furlan +27 more
2023Science Translational Medicine14 citations Open access
Semantic Scholar
TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice
Simone A. Minnie, Olivia G. Waltner, Kathleen S. Ensbey, S. Olver +15 more
2022Journal of Clinical Investigation14 citations Open access
Semantic Scholar
Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses.
G. Thangavelu, Chao Wang, Michael Loschi, A. Saha +23 more
2020Blood12 citations Open access
Semantic Scholar
Peritransplant glucocorticoids redistribute donor T cells to the bone marrow and prevent relapse after haploidentical SCT
T. Inoue, M. Koyama, K. Kaida, K. Ikegame +19 more
2021JCI Insight10 citations Open access
Semantic Scholar
CBFB-MYH11 fusion transcripts distinguish acute myeloid leukemias with distinct molecular landscapes and outcomes
Benjamin J. Huang, Jenny L. Smith, Yi-Cheng Wang, Kassra Taghizadeh +20 more
2021Blood Advances10 citations Open access
Semantic Scholar
IL-6–mediated endothelial injury impairs antiviral humoral immunity after bone marrow transplantation
Ping Zhang, Peter Fleming, C. Andoniou, Olivia G. Waltner +27 more
2024Journal of Clinical Investigation9 citations Open access
Semantic Scholar
Multiply restimulated human thymic Treg express distinct signature Treg transcription factors without evidence of exhaustion
K. Hippen, Scott N. Furlan, R. Roychoudhuri, E. Wang +11 more
2021Cytotherapy9 citations Open access
Semantic Scholar
Single-cell analysis of chromatin silencing programs in developmental and tumor progression
Steven J. Wu, Scott N. Furlan, Anca B. Mihalas, Hatice S. Kaya-Okur +12 more
2020bioRxiv8 citations Open access
Semantic Scholar
Open‐Label Phase II Trial of Amprenavir, Abacavir, and Fixed‐Dose Zidovudine/Lamivudine in Newly and Chronically HIV‐1‐Infected Patients
R. Kost, A. Hurley, Lin-Qi Zhang, M. Vesanen +7 more
2001Journal of Acquired Immune Deficiency Syndromes7 citations
Semantic Scholar
Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors
Scott N. Furlan, R. Mandraju, Travis Brewer, Kole T. Roybal +5 more
2014mAbs6 citations Open access
Semantic Scholar
EZH2-Mediated MHC Class II Silencing Drives Immune Evasion in AML with t(16;21) (FUS-ERG)
Nate J. Buteyn, Connor G. Burke, Jenny L. Smith, R. Ries +8 more
2021Blood5 citations
Semantic Scholar
Open-label phase II trial of amprenavir, abacavir, and fixed-dose zidovudine/lamivudine in newly and chronically HIV-1--infected patients.
R. Kost, A. Hurley, Lin-Qi Zhang, M. Vesanen +7 more
20015 citations Open access
Semantic Scholar
High-capacity sample multiplexing for single cell chromatin accessibility profiling
Gregory T. Booth, R. Daza, S. Srivatsan, J. McFaline-Figueroa +5 more
2023BMC Genomics4 citations Open access
Semantic Scholar
Functional consequence and therapeutic targeting of cryptic ALK fusions in monosomy 7 acute myeloid leukemia
Makia K Manselle, R. Ries, Tiffany A. Hylkema, Amanda Leonti +3 more
2023Pediatric Blood & Cancer3 citations
Semantic Scholar
Integrative Analysis of Single-Cell RNA-Seq and ATAC-Seq Data across Treatment Time Points in Pediatric AML
Lisa Wei, Diane L. Trinh, R. Ries, Dan Jin +5 more
2020Blood3 citations Open access
Semantic Scholar
Pilot Trial of Interferon-γ and Donor Lymphocyte Infusion to Treat Relapsed Myeloblastic Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation
E. Geramita, Kedwin Ventura, Shruti S. Bhise, Erika Moore +5 more
2023Transplantation and Cellular Therapy2 citations Open access
Semantic Scholar
Pharmacologic Blockade of Notch/Delta-like Ligand 4 Signaling Protects from Gastrointestinal Acute Graft-Versus-Host Disease in Non-Human Primates
V. Tkachev, F. Kuhnert, Scott N. Furlan, H. Zheng +14 more
2018Blood2 citations Open access
Semantic Scholar
Delineating tissue-specific alloimmunity during acute GVHD
V. Tkachev, Scott N. Furlan, E. L. Potter, B. Zheng +13 more
2018Journal of Immunology2 citations
Semantic Scholar
Preventing Primate GvHD Using a Novel Antagonistic Anti-CD28 Antibody Plus Rapamycin: Downregulation of CD8 Activation and Preservation of the Naïve Cell Phenotype Predicts GvHD-Free Survival
Benjamin K. Watkins, Aneesah P. Garrett, Jingyang Chen, Scott N. Furlan +3 more
20142 citations
Semantic Scholar
Erratum to “A novel technique for the fluorometric assessment of T lymphocyte antigen specific lysis” [J. Immunol. Methods 249 (2001) 99–110]
Megan E. Sheehy, A. McDermott, Scott N. Furlan, P. Klenerman +1 more
20012 citations Open access
Semantic Scholar
Identification of a Relapse Signature in t(8;21) Pediatric AML
Logan K. Wallace, Jack H. Peplinski, R. Ries, Benjamin J. Huang +4 more
2023Blood1 citations Open access
Semantic Scholar

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