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Aftab Alam · SciRah

Researcher profile · OpenAlex

Aftab Alam

Rawalpindi Women University
Department of Chemistry, Rawalpindi Women University, Rawalpindi, Pakistan
University of Malakand
Department of Chemistry, Rawalpindi Women University, Rawalpindi, Pakistan
PK

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Aftab Alam — researcher profile on SciRah

ORCID iD 0000-0003-0475-2376

Citations: 2,155
h-index: 30
i10-index: 58
Works: 108

From OpenAlex.

Synthesis and biological activitySynthesis and Characterization of Heterocyclic CompoundsNatural Antidiabetic Agents Studies

Most-cited papers

Synthesis, molecular docking and DFT analysis of novel bis-Schiff base derivatives with thiobarbituric acid for α-glucosidase inhibition assessment
Saba Gul, Faheem Jan, Aftab Alam, Abdul Shakoor +5 more
2024Scientific Reports106 citations Open access
OpenAlex
Bio-Oriented Synthesis of Novel (S)-Flurbiprofen Clubbed Hydrazone Schiff’s Bases for Diabetic Management: In Vitro and In Silico Studies
Aftab Alam, Mumtaz Ali, Najeeb Ur Rehman, Saeed Mahmud Ullah +8 more
2022Pharmaceuticals88 citations Open access
OpenAlex
Flurbiprofen derivatives as novel α-amylase inhibitors: Biology-oriented drug synthesis (BIODS), in vitro, and in silico evaluation
Momin Khan, Aftab Alam, Khalid Mohammed Khan, Uzma Salar +6 more
2018Bioorganic Chemistry87 citations
OpenAlex
Synthesis, molecular structure and urease inhibitory activity of novel bis-Schiff bases of benzyl phenyl ketone: A combined theoretical and experimental approach
Rashid M Ahmad, Momin Khan, Aftab Alam, Ahmed A. Elhenawy +5 more
2023Saudi Pharmaceutical Journal70 citations Open access
OpenAlex
Synthetic Transformation of 2-{2-Fluoro[1,1′-biphenyl]-4-yl} Propanoic Acid into Hydrazide–Hydrazone Derivatives: In Vitro Urease Inhibition and In Silico Study
Sajjad Ahmad, Momin Khan, Muhammad Ishaq Ali Shah, Mahboob Ali +3 more
2022ACS Omega68 citations Open access
OpenAlex
Novel Bis-Schiff’s base derivatives of 4-nitroacetophenone as potent α-glucosidase agents: Design, synthesis and in silico approach
Aftab Alam, Mumtaz Ali, Abdul Latif, Najeeb Ur Rehman +10 more
2022Bioorganic Chemistry65 citations
OpenAlex
Exploring the synthesis, molecular structure and biological activities of novel Bis-Schiff base derivatives: A combined theoretical and experimental approach
Sana Gul, Aftab Alam, Zainab Zainab, Mohammad Assad +6 more
2024Journal of Molecular Structure62 citations
OpenAlex
Novel Polyhydroquinoline-Hydrazide-Linked Schiff’s Base Derivatives: Multistep Synthesis, Antimicrobial, and Calcium-Channel-Blocking Activities
Zainab Zainab, Haitao Yu, Najeeb Ur Rehman, Mumtaz Ali +9 more
2022Antibiotics62 citations Open access
OpenAlex
Biooriented Synthesis of Ibuprofen-Clubbed Novel Bis-Schiff Base Derivatives as Potential Hits for Malignant Glioma: In Vitro Anticancer Activity and In Silico Approach
Muhammad Ayaz, Aftab Alam, Zainab Zainab, Mohammad Assad +9 more
2023ACS Omega53 citations Open access
OpenAlex
Novel flurbiprofen clubbed oxadiazole derivatives as potential urease inhibitors and their molecular docking study
Sajjad Ahmad, Momin Khan, Aftab Alam, Amar Ajmal +6 more
2023RSC Advances52 citations Open access
OpenAlex
Multifaceted bioactivity of thiosemicarbazide derivatives: Synthesis, characterization, and DFT investigations on inhibition of α-amylase, hydroxyl radical scavenging, and iron chelating activities with molecular docking insights
Sana Idris, Faheem Jan, Mahnoor Waheed, Aftab Alam +5 more
2024Journal of Molecular Structure50 citations
OpenAlex
Exploring the synthesis, structure, spectroscopy and biological activities of novel 4-benzylidene-1-(2-(2,4-dichloro phenyl)acetyl) thiosemicarbazide derivatives: An integrated experimental and theoretical investigation
Mahnoor Waheed, Sana Idris, Faheem Jan, Aftab Alam +6 more
2023Saudi Pharmaceutical Journal50 citations Open access
OpenAlex
Antioxidant Activity, Molecular Docking and Quantum Studies of New Bis ‐Schiff Bases Based on Benzyl Phenyl Ketone Moiety
Rashid M Ahmad, Aftab Alam, Momin Khan, Tahseen Ali +2 more
2023ChemistrySelect49 citations Open access
OpenAlex
Discovery of (S)-flurbiprofen-based novel azine derivatives as prostaglandin endoperoxide synthase-II inhibitors: Synthesis, in-vivo analgesic, anti-inflammatory activities, and their molecular docking
Aftab Alam, Mumtaz Ali, Zainab Zainab, Abdul Latif +7 more
2023Bioorganic Chemistry49 citations
OpenAlex
Bio-Oriented Synthesis of Novel Polyhydroquinoline Derivatives as α-Glucosidase Inhibitor for Management of Diabetes
Faiz Talab, Saeed Mahmud Ullah, Aftab Alam, Sobia Ahsan Halim +7 more
2023ACS Omega47 citations Open access
OpenAlex
Synthesis of new bis(dimethylamino)benzophenone hydrazone for diabetic management: In-vitro and in-silico approach
Momin Khan, Ghulam Ahad, Aftab Alam, Saeed Ullah +9 more
2023Heliyon44 citations Open access
OpenAlex
Synthesis and characterization of biologically active flurbiprofen amide derivatives as selective prostaglandin-endoperoxide synthase II inhibitors: In vivo anti-inflammatory activity and molecular docking
Aftab Alam, Mumtaz Ali, Najeeb Ur Rehman, Abdul Latif +7 more
2022International Journal of Biological Macromolecules42 citations
OpenAlex
Design, Synthesis, Crystal Structure, In Vitro and In Silico Evaluation of New N′-Benzylidene-4-tert-butylbenzohydrazide Derivatives as Potent Urease Inhibitors
Sajjad Ahmad, Momin Khan, Najeeb Ur Rehman, Muhammad Ikram +6 more
2022Molecules41 citations Open access
OpenAlex
Synthesis, Urease Inhibitory Activity, Molecular Docking, Dynamics, MMGBSA and DFT Studies of Hydrazone‐Schiff Bases Bearing Benzimidazole Scaffold
Abdul Shakoor, Faheem Jan, Sudais Rahman, Mumtaz Ali +11 more
2024Chemistry & Biodiversity40 citations
OpenAlex
Thiosemicarbazone derivatives as potent antidiabetic agents: Synthesis, in vitro, molecular docking and DFT investigations
Faheem Jan, Sana Idris, Mahnoor Waheed, Aftab Alam +3 more
2024Journal of Molecular Structure38 citations
OpenAlex
Exploring the anti-diabetic activity of benzimidazole containing Schiff base derivatives: In vitro α-amylase, α-glucosidase inhibitions and in silico studies
Abdul Shakoor, Ghulam Fareed, Imtiaz Ahmad, Ahmed A. Elhenawy +6 more
2024Journal of Molecular Structure37 citations
OpenAlex
Novel polyhydroquinoline Schiff’s base derivatives: synthesis, characterization, in vitro α-glucosidase inhibitory, and molecular docking studies
Nazish Shahab, Duanyang Kong, Mumtaz Ali, Aftab Alam +9 more
2023Research on Chemical Intermediates37 citations
OpenAlex
A study on green synthesis, characterization of chromium oxide nanoparticles and their enzyme inhibitory potential
Zainab Zainab, Shujaat Ahmad, Idrees Khan, Khalid Saeed +6 more
2022Frontiers in Pharmacology37 citations Open access
OpenAlex
Chalcones: As Potent α-amylase Enzyme Inhibitors; Synthesis, In Vitro, and In Silico Studies
Mahboob Ali, Momin Khan, Khair Zaman, Abdul Wadood +7 more
2020Medicinal Chemistry37 citations
OpenAlex
Novel acyl hydrazide derivatives of polyhydroquinoline as potent anti-diabetic and anti-glycating agents: Synthesis, in vitro α-amylase, α-glucosidase inhibition and anti-glycating activity with molecular docking insights
Sajjad Ur Rahman, Aftab Alam, Zahida Parveen, Zainab Zainab +8 more
2024Bioorganic Chemistry36 citations
OpenAlex
Synthesis, Antibacterial Activities and Theoretical Study of Polyhydroquinoline Derivatives
Muhammad Ismail, Rashid M Ahmad, Abdul Latif, Adnan Ali Khan +4 more
2023ChemistrySelect35 citations
OpenAlex
Para-Substituted Thiosemicarbazones as Cholinesterase Inhibitors: Synthesis, In Vitro Biological Evaluation, and In Silico Study
Momin Khan, Hina Gohar, Aftab Alam, Abdul Wadood +5 more
2023ACS Omega34 citations Open access
OpenAlex
Novel Benzimidazole Derivatives as Effective Inhibitors of Prolyl Oligopeptidase: Synthesis, in Vitro and in Silico Analysis
Abdul Shakoor, Aftab Alam, Faheem Jan, Momin Khan +7 more
2023Future Medicinal Chemistry31 citations
OpenAlex
Synthetic Transformation of 4-fluorobenzoic Acid to 4-fluorobenzohydrazide Schiff Bases and 1,3,4-Oxadiazole Analogs having DPPH Radical Scavenging Potential
Momin Khan, Zala Fazal, Aftab Alam, Mohammad Ibrahim +3 more
2022Letters in Drug Design & Discovery31 citations
OpenAlex
Synthesis of novel thiazole derivatives containing 3-methylthiophene carbaldehyde as potent anti α-glucosidase agents: In vitro evaluation, molecular docking, dynamics, MM-GBSA, and DFT studies
Najeeb Ullah, Aftab Alam, Zainab Zainab, Burak Tüzün +9 more
2024Journal of Molecular Structure30 citations
OpenAlex
Flurbiprofen clubbed schiff's base derivatives as potent anticancer agents: In Vitro and In Silico approach towards breast cancer
Aftab Alam, Faizullah Khan, Najeeb Ur Rehman, Zainab Zainab +6 more
2024Journal of Molecular Structure30 citations
OpenAlex
Discovering the anti-diabetic potential of thiosemicarbazone derivatives: In vitro α-glucosidase, α-amylase inhibitory activities with molecular docking and DFT investigations
Saba Gul, Ahmed A. Elhenawy, Qaisar Ali, Munir Ur Rehman +4 more
2024Journal of Molecular Structure27 citations
OpenAlex
Novel hydrazone schiff’s base derivatives of polyhydroquinoline: synthesis, in vitro prolyl oligopeptidase inhibitory activity and their Molecular docking study
Faiz Talab, Aftab Alam, Zainab Zainab, Naeem Ullah +8 more
2024Journal of Biomolecular Structure and Dynamics27 citations
OpenAlex
Synthesis of Novel Benzimidazole Analogs for Neurodegenerative Diseases by Targeting Prolyl Oligopeptidase
Abdul Shakoor, Aftab Alam, Mumtaz Ali, Naeem Ullah +7 more
2024ChemistrySelect26 citations Open access
OpenAlex
Polyhydroquinoline Derivatives for Diabetic Management: Synthesis, in Vitro and in Silico Approaches
Faiz Talab, Zainab Zainab, Aftab Alam, Mumtaz Ali +10 more
2023Future Medicinal Chemistry26 citations
OpenAlex
Synthesis, anticancer, α-glucosidase inhibition, molecular docking and dynamics studies of hydrazone-Schiff bases bearing polyhydroquinoline scaffold: In vitro and in silico approaches
Zainab Zainab, Faizullah Khan, Aftab Alam, Najeeb Ur Rehman +8 more
2024Journal of Molecular Structure24 citations
OpenAlex
Investigating Novel Thiophene Carbaldehyde Based Thiazole Derivatives as Potential Hits for Diabetic Management: Synthesis, In Vitro and In Silico Approach
Najeeb Ullah, Aftab Alam, Zainab Zainab, Ahmed A. Elhenawy +5 more
2024ChemistrySelect24 citations Open access
OpenAlex
Designing and Synthesis of Novel Fexofenadine‐Derived Hydrazone‐Schiff Bases as Potential Urease Inhibitors: In‐Vitro, Molecular Docking and DFT Investigations
Muhammad Ayaz, Aftab Alam, Zainab Zainab, Ahmed A. Elhenawy +6 more
2024Chemistry & Biodiversity23 citations
OpenAlex
Synthesis of novel 2-mercapto-1,3,4-oxadiazole derivatives as potent urease inhibitors: In vitro and in silico investigations
Aziz Khan, Ahmed A. Elhenawy, Munir Ur Rehman, Manawwer Alam +3 more
2024Journal of Molecular Structure21 citations Open access
OpenAlex
Synthesis of Some Novel 4-bromobenzoic Acid Clubbed Hydrazone Schiff Base Derivatives as Potent α-amylase Inhibitors: In vitro and In silico Studies
Momin Khan, Faima Alam, Aftab Alam, Abdul Wadood +6 more
2024Letters in Drug Design & Discovery21 citations
OpenAlex
Synthesis and Molecular Docking Study of Hydrazone Schiff Bases of α‐Naphthalene‐Containing Alkyl Phenyl Ether Fragment as Potent α‐Amylase and α‐Glucosidase Inhibitors
Tanzeela Ahmad Shah, Aftab Alam, Zainab Zainab, Mohammad Assad +7 more
2024ChemistrySelect20 citations
OpenAlex
Exploring the anti-diabetic potential of bis-Schiff base derivatives of benzimidazole: In-Vitro α-amylase, α-glucosidase inhibition, molecular docking, ADMET and DFT studies
Hamid Ullah, Aftab Alam, Ahmed A. Elhenawy, Imtiaz Ahmad +3 more
2025Computational Biology and Chemistry19 citations
OpenAlex
Experimental and computational profiling of novel bis-Schiff base derivatives bearing α-naphthalene moiety as potential tyrosinase inhibitors
Tanzeela Ahmad Shah, Tanzeela Ahmad Shah, Aftab Alam, Zainab Zainab +7 more
2024Journal of Molecular Structure19 citations
OpenAlex
Synthesis of novel (S)-flurbiprofen-based esters for cancer treatment by targeting thymidine phosphorylase via Biomolecular Approaches
Aftab Alam, Zainab Zainab, Majid Khan, Sobia Ahsan Halim +7 more
2024Journal of Molecular Structure14 citations
OpenAlex
Exploring 1,3,4-Oxadiazole derivatives of 3,4-Dihydroxyphenylacetic acid as potent α-glucosidase inhibitors: Synthesis, structure-activity relationship, molecular docking, and DFT studies
Hammad Khan, Hammad Khan, Faheem Jan, Aqsa Aqsa +10 more
2024Journal of Molecular Structure13 citations
OpenAlex
Investigating the Tyrosinase Inhibitory Activity of 4‐Bromobenzoic Acid Hydrazone‐Schiff Bases: In Vitro , Molecular Structure and Docking Studies
Faima Alam, Muhammad Ismail, Masroor Kamal, Fayaz Ur Rahman +4 more
2024ChemistrySelect13 citations
OpenAlex
Synthesis and Multi‐Target Inhibition of Bis ‐Schiff Bases of Barbituric Acid: in Vitro α‐glucosidase, α‐amylase Inhibitory Activities With Docking and DFT Studies
Mahnoor Zahir, Aftab Alam, Faheem Jan, Ajmal Khan +4 more
2024ChemistrySelect12 citations
OpenAlex
Synthesis, characterization, enzyme inhibition and molecular docking studies of benzothiazole derivatives bearing alkyl phenyl ether fragments
Muhammad Usman, Aftab Alam, Zainab Zainab, Majid Khan +7 more
2024Journal of Molecular Structure12 citations
OpenAlex
Synthesis of Flurbiprofen Based Amide Derivatives as Potential Leads for Diabetic Management: In Vitro α‐glucosidase Inhibition, Molecular Docking and DFT Simulation Approach
Aftab Alam, Zainab Zainab, Ahmed A. Elhenawy, Najeeb Ur Rehman +6 more
2024ChemistrySelect12 citations
OpenAlex
Flurbiprofen Derivatives as Potential DPPH and ABTS Radical Scavengers
Momin Khan, Aftab Alam, Uzma Salar, Sridevi Chigurupati +4 more
2023Russian Journal of Organic Chemistry12 citations
OpenAlex

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Citations per year

12 in 2026

20182026

Frequent co-authors

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Manzoor AhmadUniversity of Malakand×26
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Mumtaz AliUniversity of Malakand×25
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Mumtaz Ali — researcher profile on SciRah
Momin KhanAbdul Wali Khan University Mardan×22
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Momin Khan — researcher profile on SciRah
Zainab ZainabHebei Normal University

×21

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Zainab Zainab — researcher profile on SciRah

Ahmed Al‐HarrasiUniversity of Nizwa×21

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Ahmed Al‐Harrasi — researcher profile on SciRah

Ahmed A. ElhenawyAl-Azhar University×16

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Ahmed A. Elhenawy — researcher profile on SciRah

Najeeb Ur RehmanUniversity of Nizwa×15

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Najeeb Ur Rehman — researcher profile on SciRah

Abdul LatifUniversity of Malakand×14

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Abdul Latif — researcher profile on SciRah

Fawaz F. AlasmariKing Saud University×13

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Fawaz F. Alasmari — researcher profile on SciRah

Abdullah F. AlasmariKing Saud University×12

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Abdullah F. Alasmari — researcher profile on SciRah

Ajmal KhanUniversity of Nizwa×11

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Ajmal Khan — researcher profile on SciRah

Muhammad AyazUniversity of Malakand×10

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Muhammad Ayaz — researcher profile on SciRah

Affiliation history

Jiwaji University2021
Shandong University2024
Galgotias University2021
Abdul Wali Khan University Mardan2018–2023
Jamia Hamdard2000–2026
Abbottabad University of Science and Technology2025
Rawalpindi Women University2025–2026
University of Malakand2022–2026