Synthesis of novel thiazole derivatives containing 3-methylthiophene carbaldehyde as potent anti α-glucosidase agents: In vitro evaluation, molecular docking, dynamics, MM-GBSA, and DFT studies

Najeeb Ullah^a, Aftab Alam^a, Zainab Zainab^b, Burak Tüzün^c, Najeeb Ur Rehman^d, Muhammad Ayaz^a, Ahmed A. Elhenawy^{e f}, Ajmal Khan^d, Sajjad Ur Rahman^a, Mumtaz Ali^a, Abdul Latif^a, Ahmed Al-Harrasi^d✉, Manzoor Ahmad^a✉

1. ^aDepartment of Chemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan
2. ^bCollege of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang 050024, China
3. ^cPlant and Animal Production Department, Technical Sciences Vocational School of Sivas, Sivas Cumhuriyet University, Sivas, Turkey
4. ^dNatural and Medical Sciences Research Center, University of Nizwa, Nizwa 616, Oman
5. ^eChemistry Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Cairo, Egypt
6. ^fChemistry Department, Faculty of Science, Al-Baha University, Al-Bahah 65731, Saudi Arabia
7. ✉Corresponding author