Synthesis of novel (S)-flurbiprofen-based esters for cancer treatment by targeting thymidine phosphorylase via Biomolecular Approaches

Aftab Alam^a, Zainab Zainab^b, Majid Khan^{c d}, Sobia Ahsan Halim^d, Najeeb Ur Rehman^d, Muhammad Ayaz^a, Ajmal Khan^d, Mumtaz Ali^a✉, Abdul Latif^a, Ahmed Al‐Harrasi^d✉, Manzoor Ahmad^d✉

1. ^aDepartment of Chemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan
2. ^bCollege of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang 050024, China
3. ^cDepartment of Biochemistry, University of Malakand, P.O. Box 18800, Dir Lower, Khyber Pakhtunkhwa, Pakistan
4. ^dNatural and Medical Sciences Research Center, University of Nizwa, P.O. Box 33, PC 616, Birkat Al Mauz, Nizwa, Sultanate of Oman
5. ✉Corresponding author