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D. Carini · SciRah

Researcher profile · Semantic Scholar

D. Carini

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D. Carini — researcher profile on SciRah

h-index: 24
Works: 75
Citations: 5,233

Most-cited papers

Angiotensin II receptors and angiotensin II receptor antagonists.
P. Timmermans, P. Wong, Andrew T. Chiu, W. Herblin +6 more
1993Pharmacological Reviews1,951 citations
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives.
D. Carini, J. Duncia, P. Aldrich, Andrew T. Chiu +6 more
1991Journal of Medicinal Chemistry385 citations Open access
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists. XI. Pharmacology of EXP3174: an active metabolite of DuP 753, an orally active antihypertensive agent.
P. Wong, W. Price, Andrew T. Chiu, J. Duncia +4 more
1990Journal of Pharmacology and Experimental Therapeutics331 citations
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists. VII. Cellular and biochemical pharmacology of DuP 753, an orally active antihypertensive agent.
Andrew T. Chiu, D. E. Mccall, W. Price, P. Wong +6 more
1990Journal of Pharmacology and Experimental Therapeutics329 citations
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists. VIII. Characterization of functional antagonism displayed by DuP 753, an orally active antihypertensive agent.
P. Wong, W. Price, Andrew T. Chiu, J. Duncia +4 more
1990Journal of Pharmacology and Experimental Therapeutics281 citations
Semantic Scholar
The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives.
J. Duncia, Andrew T. Chiu, D. Carini, George B. Gregory +6 more
1990Journal of Medicinal Chemistry221 citations Open access
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists. IX. Antihypertensive activity in rats of DuP 753, an orally active antihypertensive agent.
P. Wong, W. Price, Andrew T. Chiu, J. Duncia +4 more
1990Journal of Pharmacology and Experimental Therapeutics211 citations
Semantic Scholar
Hypotensive action of DuP 753, an angiotensin II antagonist, in spontaneously hypertensive rats. Nonpeptide angiotensin II receptor antagonists: X.
P. Wong, W. Price, Andrew T. Chiu, J. Duncia +4 more
1990HYPERTENSION177 citations Open access
Semantic Scholar
Discrimination of angiotensin II receptor subtypes by dithiothreitol.
Andrew T. Chiu, D. E. Mccall, Tam T. Nguyen, D. Carini +7 more
1989European Journal of Pharmacology137 citations
Semantic Scholar
Nonpeptide Angiotensin II Receptor Antagonists: Studies With EXP9270 and DuP 753
P. Wong, W. Price, Andrew T. Chiu, D. Carini +4 more
1990HYPERTENSION130 citations Open access
Semantic Scholar
(Trimethylsilyl)cyclopentene annulation: a regiocontrolled approach to the synthesis of five-membered rings
R. Danheiser, D. Carini, A. Basak
1981123 citations
Semantic Scholar
Scope and stereochemical course of the (trimethylsilyl)cyclopentene annulation
R. Danheiser, D. Carini, David M. Fink, A. Basak
198390 citations
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists. I. Pharmacological characterization of 2-n-butyl-4-chloro-1-(2-chlorobenzyl)imidazole-5-acetic acid, sodium salt (S-8307).
Pancras C. Wong, Andrew T. Chiu, W. Price, M. Thoolen +4 more
1988Journal of Pharmacology and Experimental Therapeutics88 citations
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists. III. Structure-function studies.
Andrew T. Chiu, J. Duncia, D. E. Mccall, P. Wong +5 more
1989Journal of Pharmacology and Experimental Therapeutics81 citations
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists: N-[(benzyloxy)benzyl]imidazoles and related compounds as potent antihypertensives.
D. Carini, J. Duncia, A. L. Johnson, Andrew T. Chiu +3 more
1990Journal of Medicinal Chemistry69 citations
Semantic Scholar
Scope and stereochemical course of the addition of (trimethylsilyl)allenes to ketones and aldehydes. A regiocontrolled synthesis of homopropargylic alcohols
R. Danheiser, D. Carini, Carrie A. Kwasigroch
198669 citations
Semantic Scholar
Angiotensin II Receptor Antagonists From Discovery to Antihypertensive Drugs
P. Timmermans, D. Carini, Andrew T. Chiu, J. Duncia +5 more
1991HYPERTENSION65 citations
Semantic Scholar
(Trimethylsilyl)allenes as propargylic anion equivalents: synthesis of homopropargylic alcohols and ethers
R. Danheiser, D. Carini
198059 citations
Semantic Scholar
Discovery of losartan, the first angiotensin II receptor antagonist.
P. B. M. W. M. Timmermans, J. Duncia, D. Carini, Andrew T. Chiu +3 more
1995Journal of Human Hypertension56 citations
Semantic Scholar
Pharmacology of DuP 532, a selective and noncompetitive AT1 receptor antagonist.
P. Wong, S. Hart, Andrew T. Chiu, W. Herblin +4 more
1991Journal of Pharmacology and Experimental Therapeutics50 citations
Semantic Scholar
Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3
Eddy W. Yue, C. Higley, Dimeo Susan, D. Carini +15 more
200245 citations Open access
Semantic Scholar
Practical synthesis and regioselective alkylation of methyl 4(5)-(pentafluoroethyl)-2-propylimidazole-5(4)-carboxylate to give DuP 532, a potent angiotensin II antagonist
M. Pierce, D. Carini, George F. Huhn, G. Wells +1 more
199339 citations
Semantic Scholar
Identification of selective inhibitors of cyclin dependent kinase 4.
D. Carini, R. Kaltenbach, Jie Liu, P. Benfield +15 more
2001Bioorganic & Medicinal Chemistry Letters38 citations Open access
Semantic Scholar
Potent imidazole angiotensinII antagonists: acyl sulfonamides and acyl sulfamides as tetrazole replacements
E. M. Naylor, P. Chakravarty, Colleen A. Costello, R. Chang +11 more
199424 citations
Semantic Scholar
Inhibitors of HIV-1 attachment: The discovery and structure-activity relationships of tetrahydroisoquinolines as replacements for the piperazine benzamide in the 3-glyoxylyl 6-azaindole pharmacophore.
Jacob J. Swidorski, Zheng Liu, Z. Yin, Tao Wang +11 more
2016Bioorganic & Medicinal Chemistry Letters22 citations
Semantic Scholar
(N-acyl-N-alkyl)glycyl borolysine analogs: A new class of potent thrombin inhibitors
R. Galemmo, J. Fevig, D. Carini, J. Cacciola +14 more
199617 citations
Semantic Scholar
Nonpeptide Angiotensin II Receptor Antagonists: The Discovery of a Series of N‐(Biphenylylmethyl)imidazoles as Potent, Orally Active Antihypertensives.
D. Carini, J. Duncia, P. Aldrich, Andrew T. Chiu +9 more
199117 citations
Semantic Scholar
The discovery and development of angiotensin II antagonists.
D. Carini, David D. Christ, J. Duncia, M. Pierce
1998Pharmaceutical biotechnology15 citations
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists: a novel class of antihypertensive agents.
P. B. Timmermans, D. Carini, Andrew T. Chiu, J. Duncia +5 more
1990Blood & Vessel15 citations
Semantic Scholar
Nonpeptide Angiotensin II Receptor Antagonist: Losartan
Ronald D. Smith, J. Duncia, Robert J. Lee, D. Christ +6 more
199314 citations
Semantic Scholar
S1 heterocyclic thrombin inhibitors
C. Dominguez, D. Carini, P. Weber, R. Knabb +3 more
199713 citations
Semantic Scholar
Balanced angiotensin II receptor antagonists. III. The effects of substitution at the imidazole 5-position.
J. Santella, J. Duncia, C. Ensinger, Mary K. VanAtten +5 more
199413 citations
Semantic Scholar
The preparation of (perfluoroalkyl)imidazoles as nonpeptide angiotensin II receptor antagonists
D. Carini, Andrew T. Chiu, P. Wong, A. L. Johnson +2 more
199313 citations
Semantic Scholar
Nonpeptide angiotensin II receptor antagonists: the discovery of DMP 581 and DMP 811
D. Carini, Ardecky Rj, C. Ensinger, J. Pruitt +5 more
199412 citations
Semantic Scholar
EXP 6803, A Nonpeptide Angiotensin II Receptor Antagonist
P. Wong, W. Price, Andrew T. Chiu, N. Wong +4 more
198911 citations
Semantic Scholar
Balanced angiotensin II receptor antagonists. I. The effects of biphenyl “ortho”-substitution on AT1/AT2 affinities
Mi-Mi L. Quan, R. Olson, D. Carini, C. Ellis +8 more
19947 citations
Semantic Scholar
Developments in antiviral drug design, discovery and development in 2004.
N. Meanwell, M. Belema, D. Carini, S. D'Andrea +9 more
2005Current Drug Targets - Infectious Disorders6 citations
Semantic Scholar
Angiotensin II receptor blocking imidazoles and their combinations with diuretics and NSAIDs
D. Carini, P. Wong, J. Duncia
19893 citations
Semantic Scholar
Synthesis and evaluation of indenopyrazoles as cyclin-dependent kinase inhibitors. 3. Structure activity relationships at C3(1,2).
Eddy W. Yue, C. Higley, S. Dimeo, D. Carini +15 more
2002Journal of Medicinal Chemistry2 citations
Semantic Scholar
Pharmacology and pharmacokinetics of a novel nonpeptide angiotensin II receptor antagonist--DMP 811.
Pancras C. Wong, Shiew-Mei Huang, Robert J. Ardecky, D. Carini +6 more
1995Clinical and experimental hypertension2 citations
Semantic Scholar
Reviewer Acknowledgment for Volume 9
J. Aho, J. Aitken, Sarah Albright, S. Ambrosio +39 more
2017Anatomical Sciences Education1 citations Open access
Semantic Scholar
Practical Synthesis and Regioselective Alkylation of Methyl 4(5)‐( Pentafluoroethyl)‐2‐propylimidazole‐5(4)‐carboxylate to give DuP 532, a Potent Angiotensin II Antagonist.
M. Pierce, D. Carini, George F. Huhn, G. Wells +1 more
20101 citations
Semantic Scholar
S1 Heterocyclic Thrombin Inhibitors.
C. Dominguez, D. Carini, P. Weber, R. Knabb +3 more
19971 citations
Semantic Scholar
(N‐Acyl‐N‐alkyl)glycyl Borolysine Analogues: A New Class of Potent Thrombin Inhibitors.
R. A. Jun. Galemmo, J. Fevig, D. Carini, J. Cacciola +14 more
19971 citations
Semantic Scholar
Emilia-Romagna Regional Blood System accreditation as an example of improvement through application of specific requirements: a retrospective analysis
Pilade Cortellazzi, D. Carini, L. Bolzoni, E. Cattadori +1 more
2021BMJ Open Quality0 citations Open access
Semantic Scholar
Optimized suspension of vehicles, and related kits
D. Carini, D. Fattori
20150 citations
Semantic Scholar
Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors
D. Carini, C. Burton, S. Seitz
20060 citations
Semantic Scholar
Macrocyclic isochinolinpeptidinhibitoren of the Hepatitis C virus
F. Mcphee, J. Campbell, Wenying Li, D. AndreaStanley +6 more
20040 citations
Semantic Scholar
Comparative QSAR: Angiotensin II Antagonists
A. Kurup, Rajni Garg, D. Carini, C. Hansch
20010 citations
Semantic Scholar
Nd growth inhibitory agent
D. Nugiel, D. Carini, Eddy W. Yue, S. Dimeo
19990 citations
Semantic Scholar

Frequent co-authors

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R. Wexler×22
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R. Wexler — researcher profile on SciRah
P. Wong×21
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J. Duncia×20
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Andrew T. Chiu×19
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×16

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A. L. Johnson — researcher profile on SciRah

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W. Price — researcher profile on SciRah

P. Timmermans×15

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G. Wells — researcher profile on SciRah

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M. Pierce — researcher profile on SciRah

P. B. Timmermans×5

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P. B. Timmermans — researcher profile on SciRah

Andrew T. Chiu×5

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Andrew T. Chiu — researcher profile on SciRah

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W. Herblin — researcher profile on SciRah