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M. Canouil · SciRah

Researcher profile · Semantic Scholar

M. Canouil

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M. Canouil — researcher profile on SciRah

h-index: 32
Works: 76
Citations: 7,180

Most-cited papers

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
A. Mahajan, D. Taliun, Matthias Thurner, N. Robertson +111 more
2018Nature Genetics1,497 citations Open access
Semantic Scholar
A catalog of genetic loci associated with kidney function from analyses of a million individuals
M. Wuttke, Yong Li, Man Li, Karsten B. Sieber +324 more
2019Nature Genetics767 citations Open access
Semantic Scholar
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
M. Feitosa, A. Kraja, D. Chasman, Yun J. Sung +269 more
2018PLoS ONE764 citations Open access
Semantic Scholar
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A. Mahajan, C. Spracklen, Wei-Hua Zhang, M. Ng +345 more
2022Nature Genetics616 citations Open access
Semantic Scholar
Genetic drivers of heterogeneity in type 2 diabetes pathophysiology
Ken Suzuki, K. Hatzikotoulas, L. Southam, H. Taylor +360 more
2024Nature540 citations Open access
Semantic Scholar
The Trans-Ancestral Genomic Architecture of Glycemic Traits
Ji Chen, C. Spracklen, G. Marenne, Arushi Varshney +404 more
2021Nature Genetics465 citations Open access
Semantic Scholar
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
A. Mahajan, J. Wessel, Sara M. Willems, Wei Zhao +236 more
2017Nature Genetics403 citations Open access
Semantic Scholar
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Yun J. Sung, T. Winkler, L. de las Fuentes, Amy R. Bentley +293 more
2018American Journal of Human Genetics134 citations Open access
Semantic Scholar
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Amy R. Bentley, Yun J. Sung, Michael R. Brown, T. Winkler +298 more
2019Nature Genetics122 citations Open access
Semantic Scholar
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions
P. D. de Vries, Michael R. Brown, Amy R. Bentley, Yun J. Sung +262 more
2019112 citations
Semantic Scholar
A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity.
J. Bradfield, S. Vogelezang, J. Felix, A. Chesi +95 more
2019Human Molecular Genetics110 citations Open access
Semantic Scholar
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
N. Pervjakova, Gunn-Helen Moen, M. Borges, T. Ferreira +69 more
2022Human Molecular Genetics109 citations Open access
Semantic Scholar
Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.
L. Marselli, A. Piron, M. Suleiman, M. Colli +32 more
2020Cell Reports95 citations Open access
Semantic Scholar
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Tuomas O. Kilpeläinen, Amy R. Bentley, R. Noordam, Yun J. Sung +233 more
2019Nature Communications87 citations Open access
Semantic Scholar
Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension
Morgane Baron, Julie Maillet, Marlène Huyvaert, A. Dechaume +27 more
2019Nature Medicine85 citations Open access
Semantic Scholar
Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study
Agata Wesolowska-Andersen, C. Brorsson, R. Bizzotto, A. Mari +56 more
2022Cell Reports Medicine80 citations Open access
Semantic Scholar
Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes
A. Abderrahmani, L. Yengo, R. Caiazzo, M. Canouil +34 more
2017Diabetes80 citations Open access
Semantic Scholar
Hepatic DPP4 DNA Methylation Associates With Fatty Liver
C. Baumeier, S. Saussenthaler, A. Kammel, M. Jähnert +13 more
2016Diabetes74 citations
Semantic Scholar
Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion
F. Ndiaye, Ana Ortalli, M. Canouil, Marlène Huyvaert +18 more
2017Molecular Metabolism71 citations Open access
Semantic Scholar
Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles
M. Verbanck, M. Canouil, A. Leloire, Véronique Dhennin +4 more
2017PLoS ONE70 citations Open access
Semantic Scholar
Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice
Gaelle R. Carrat, Ming Hu, M. Nguyen-Tu, Pauline Chabosseau +22 more
2017American Journal of Human Genetics69 citations Open access
Semantic Scholar
Elevated circulating follistatin associates with an increased risk of type 2 diabetes
Chuan-Yan Wu, Y. Borné, Rui Gao, Maykel López Rodríguez +38 more
2021Nature Communications63 citations Open access
Semantic Scholar
Relationship between salivary/pancreatic amylase and body mass index: a systems biology approach
A. Bonnefond, L. Yengo, A. Dechaume, M. Canouil +16 more
2017BMC Medicine63 citations Open access
Semantic Scholar
Type 2 diabetes–associated variants of the MT2 melatonin receptor affect distinct modes of signaling
A. Karamitri, B. Plouffe, A. Bonnefond, Min Chen +13 more
2018Science Signaling62 citations
Semantic Scholar
Pathogenic variants in actionable MODY genes are associated with type 2 diabetes
A. Bonnefond, M. Boissel, A. Bolze, E. Durand +23 more
2020Nature Metabolism58 citations Open access
Semantic Scholar
Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
A. Mahajan, D. Taliun, Matthias Thurner, N. Robertson +102 more
2018bioRxiv56 citations Open access
Semantic Scholar
The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward
F. Ndiaye, Marlène Huyvaert, Ana Ortalli, M. Canouil +13 more
2019International Journal of Obesity49 citations Open access
Semantic Scholar
Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies
E. Tobi, D. Juvinao-Quintero, J. Ronkainen, Raffael Ott +47 more
2022Diabetes Care42 citations Open access
Semantic Scholar
SHP2 drives inflammation-triggered insulin resistance by reshaping tissue macrophage populations
Romain Paccoud, Céline Saint-Laurent, E. Piccolo, Mylène Tajan +29 more
2021Science Translational Medicine42 citations
Semantic Scholar
Identification of biomarkers for glycaemic deterioration in type 2 diabetes
R. Slieker, L. Donnelly, Elina Akalestou, Livia Lopez-Noriega +62 more
2023Nature Communications39 citations Open access
Semantic Scholar
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Yun J. Sung, L. de las Fuentes, T. Winkler, D. Chasman +277 more
2019Human Molecular Genetics39 citations Open access
Semantic Scholar
Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes
A. Khamis, M. Canouil, A. Siddiq, Hutokshi Crouch +16 more
2019Molecular Metabolism37 citations Open access
Semantic Scholar
High morbidity and mortality in children with untreated congenital deficiency of leptin or its receptor
S. Saeed, R. Khanam, Q. M. Janjua, J. Manzoor +13 more
2023medRxiv30 citations Open access
Semantic Scholar
Epigenome-Wide Association Study Reveals Methylation Loci Associated With Offspring Gestational Diabetes Mellitus Exposure and Maternal Methylome
M. Canouil, A. Khamis, E. Keikkala, S. Hummel +11 more
2021Diabetes Care28 citations Open access
Semantic Scholar
Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications
Ken Suzuki, K. Hatzikotoulas, L. Southam, H. Taylor +347 more
2023medRxiv27 citations Open access
Semantic Scholar
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
L. de las Fuentes, Yun J. Sung, R. Noordam, T. Winkler +218 more
2020Molecular Psychiatry22 citations Open access
Semantic Scholar
Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study.
Lise Folon, Morgane Baron, B. Toussaint, E. Vaillant +15 more
2023The Lancet Diabetes and Endocrinology21 citations Open access
Semantic Scholar
Rare Variant Analysis of Obesity-Associated Genes in Young Adults With Severe Obesity From a Consanguineous Population of Pakistan.
S. Saeed, Q. M. Janjua, A. Haseeb, R. Khanam +12 more
2022Diabetes21 citations Open access
Semantic Scholar
NACHO: an R package for quality control of NanoString nCounter data
M. Canouil, G. Bouland, A. Bonnefond, P. Froguel +2 more
2019Bioinform.20 citations Open access
Semantic Scholar
A framework for conducting GWAS using repeated measures data with an application to childhood BMI
K. Burrows, A. Heiskala, J. Bradfield, Z. Balkhiyarova +16 more
2024Nature Communications17 citations Open access
Semantic Scholar
Histone deacetylase 9 promoter hypomethylation associated with adipocyte dysfunction is a statin-related metabolic effect
A. Khamis, R. Boutry, M. Canouil, S. Mathew +6 more
2019bioRxiv17 citations Open access
Semantic Scholar
Functional genetics reveals the contribution of delta opioid receptor to type 2 diabetes and beta-cell function
Sarah Meulebrouck, Judith Merrheim, G. Quéniat, Cyril Bourouh +26 more
2024Nature Communications12 citations Open access
Semantic Scholar
Monogenic diabetes characteristics in a transnational multicenter study from Mediterranean countries.
M. Vaxillaire, A. Bonnefond, S. Liatis, L. Ben Salem Hachmi +20 more
2020Diabetes Research and Clinical Practice10 citations Open access
Semantic Scholar
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion
Ming Hu, Inês Cebola, Gaelle R. Carrat, Shuying Jiang +14 more
2021Cell Reports9 citations Open access
Semantic Scholar
Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants
Alan Hegron, E. Huh, X. Deupi, B. Sokrat +13 more
2021ACS Pharmacology & Translational Science9 citations Open access
Semantic Scholar
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a new regulator of insulin secretion
Ming Hu, Inês Cebola, Gaelle R. Carrat, Shuying Jiang +14 more
2019bioRxiv9 citations Open access
Semantic Scholar
Genome-wide Association Study of Change in Fasting Glucose over time in 13,807 non-diabetic European Ancestry Individuals
Ching-Ti Liu, J. Merino, D. Rybin, Daniel A. DiCorpo +46 more
2019Scientific Reports8 citations Open access
Semantic Scholar
Variable Clustering in High-Dimensional Linear Regression: The R Package clere
L. Yengo, J. Jacques, C. Biernacki, M. Canouil
2016The R Journal6 citations Open access
Semantic Scholar
Identification of myokines susceptible to improve glucose homeostasis after bariatric surgery.
L. Orioli, M. Canouil, K. Sawadogo, Li Ning +9 more
2023European Journal of Endocrinology5 citations Open access
Semantic Scholar
Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose
M. Canouil, B. Balkau, R. Roussel, P. Froguel +1 more
2018Frontiers in Genetics5 citations Open access
Semantic Scholar

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